Robidone
Robidone Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Robidone is a brand name. Its generic name is Hydrocodone.
Robidone
Robidone is an opioid pain medication used to treat moderate to severe pain. It is typically used when other medications aren’t strong enough to provide sufficient pain relief. It can be prescribed in the form of a pill, tablet, liquid, or injection. The most common brand names for this medication are Vicodin, Lortab, and Hycodan.
Uses for
Robidone is used as a pain reliever and is sometimes prescribed for symptoms of a cold or flu. It may also be used as a cough suppressant in certain patients. It is also effective in treating moderate to severe chronic pain, such as in people with cancer.
Mechanism of Action
Robidone works by attaching to opioid receptors in the brain to initiate its effects. It causes an increase in dopamine activity, which is responsible for its pain-relieving effects. It can also act on the respiratory center in the brain to suppress a cough.
How Long Does It Take To Work?
The effects of taking hydrocodone can be felt within about 15 to 30 minutes after taking it. However, it can take longer for the effects to be fully experienced. It also takes different amounts of time for the effects to wear off, depending on the dosage and how it’s taken.
Absorption
Robidone is rapidly and almost completely absorbed after it is taken orally. The peak level of hydrocodone in the bloodstream occurs approximately 1 hour after it is taken.
Route of Elimination
Robidone is primarily eliminated by hepatic metabolism. It is also eliminated in the urine and the feces in smaller amounts.
Dosage
The recommended starting dose of hydrocodone for adults is 5 mg to 10 mg taken orally every 4 to 6 hours as needed for pain relief. The maximum recommended dose of hydrocodone is 80 mg per day for adults.
Administration
Robidone can be taken orally in the form of a pill, tablet, liquid, or injection. It should be taken with food or milk to help prevent stomach upset.
Side Effect
Common side effects of taking hydrocodone include dizziness, drowsiness, constipation, nausea, vomiting, and headache. It can also cause sweating, dry mouth, and hypertension. In rare cases, it may cause an allergic reaction or worsen existing breathing problems.
Toxicity
Taking too much hydrocodone can cause severe symptoms of overdose such as breathing problems, confusion, fainting, coma, and even death. Overdose often occurs when hydrocodone is combined with other drugs, such as alcohol or benzodiazepines.
Precautions
Before taking hydrocodone, it is important to inform your doctor if you are pregnant, breastfeeding, or have any allergies. It is also important to let your doctor know if you have asthma, COPD, or any liver or kidney problems. Additionally, it is important to avoid driving or operating machinery while taking this medication due to its sedative effects.
Interactions
The effects of taking hydrocodone with other drugs can be unpredictable. Therefore, it is important to inform your doctor about any other medications that are being taken at the same time. Robidone can interact with other drugs, such as alcohol, antidepressants, muscle relaxants, and antihistamines.
Disease Interactions
Robidone may interact with certain diseases, such as breathing disorders, high blood pressure, mental health conditions, and seizure disorders. It is important to inform your doctor of any other medical conditions prior to taking this medication.
Drug Interactions
Robidone may interact with certain drugs, such as alcohol, antidepressants, muscle relaxants, and antihistamines. It is important to inform your doctor of any other medications that are being taken at the same time.
Food Interactions
Robidone should be taken with food or milk to help prevent stomach upset. It is also important to avoid drinking large amounts of alcohol while taking this medication due to its sedative effects.
Pregnancy Use
Robidone should not be used during pregnancy as it can pass through the baby’s placenta and cause the baby to become dependent on the drug. It can also cause premature labor and low birth weight.
Lactation Use
Robidone is excreted into breast milk and should not be used while breastfeeding. The effects on the baby are unknown and could be harmful.
Acute Overdose
It is important to seek medical attention immediately if an overdose of hydrocodone is suspected. Symptoms of an overdose include confusion, breathing problems, coma, and even death. It is important to never take more than the recommended dose of this medication.
Contraindication
Robidone should not be taken if a patient is allergic to it or any of its components. It should also be avoided in patients with breathing problems, mental health conditions, and seizure disorders.
Use Directions
It is important to follow the directions on the label exactly when taking hydrocodone. Do not take more or less medication than recommended by the doctor. Do not take it more often or for a longer period of time than prescribed by the doctor.
Storage Condition
Robidone should be stored in a cool, dry place out of reach of children. It should also be kept away from direct sunlight and heat.
Volume of Distribution
The volume of distribution of hydrocodone is 2.1 to 3.2 L/kg.
Half Life
The half life of hydrocodone is 3.8 to 4.5 hours.
Clearance
The clearance of hydrocodone is 2.3 to 3.7 mL/min/kg.
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