Progenta Ee

Progenta Ee Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Progenta Ee is a brand name. Its generic name is Gentamicin.

Progenta Ee Introduction

Progenta Ee is an antibiotic in the aminoglycoside family. It is usually prescribed to treat a variety of bacterial infections. It works by inhibiting the growth of bacteria. Progenta Ee is available in injection, ointment, capsule, and eye drop form.

Uses for Progenta Ee

Progenta Ee is used to treat serious bacterial infections including pneumonia, meningitis, septicemia, endocarditis, and urinary tract infections. It is also used to prevent post-operative infections.

Mechanism of Action

Progenta Ee works by inhibiting bacterial protein synthesis. It binds to and alters the ribosomes in bacterial cells, blocking vital processes leading to cell death.

How Long Does it Take to Work?

The effects of gentamicin begin within one to two hours after administration. Depending on the severity of infection, improvement may be noticed in as early as 24 hours.

Absorption

Progenta Ee is poorly absorbed when taken orally. When administered intravenously (IV), it is rapidly and completely absorbed.

Route of Elimination

Progenta Ee is eliminated mainly in the kidney, with only a small amount being excreted in the faeces.

Dosage

The dosage of gentamicin varies depending on the individual and the type of infection being treated. Typical doses in adults and children over 12 years of age include:

  • IV route: 2-3 mg/kg per day, divided into 2 or 3 doses a day
  • Oral route: 2-3 mg/kg/day, divided into 2 or 3 doses a day.

Administration

Progenta Ee can be administered intravenously (IV) or orally. It can also be administered transdermally as an ointment to treat infected skin.

Side Effects

Common side effects of gentamicin include nausea, vomiting, abdominal pain, diarrhea, rash, itching, headache, dizziness, vertigo, and tinnitus.

Toxicity

Progenta Ee is potentially toxic. It can cause permanent hearing loss, kidney damage, and neuromuscular paralysis. It is important not to exceed the recommended dose.

Precaution

Progenta Ee should be used with caution in people with impaired renal or hepatic function, as well as those with hearing impairment. It should not be used to treat viral infections.

Interaction

Progenta Ee can interact with certain drugs, such as other antibiotics, seizure medications, and diuretics. Tell your doctor about all medications you are taking to avoid potential drug interactions.

Disease Interaction

Progenta Ee can increase the risk of kidney damage in people with diabetes. It can also increase the risk of hearing impairment in people with myasthenia gravis and muscular dystrophy.

Drug Interaction

Progenta Ee can interact with other medications including antibiotics, seizure medications, and diuretics. Tell your doctor about all drugs you are taking to avoid potential drug interactions.

Food Interactions

Progenta Ee may interact with certain foods, such as dairy products. It is important to take gentamicin on an empty stomach or several hours after meals.

Pregnancy Use

Progenta Ee is generally considered safe to use during pregnancy. However, it should be used with caution in women with preterm labor, as extra caution should be taken to prevent early delivery.

Lactation Use

Progenta Ee is generally considered safe to use while breastfeeding. However, it is important to tell your doctor if you are breastfeeding before taking gentamicin.

Acute Overdose

Overdosing on gentamicin can cause hearing loss, kidney damage, nephrotoxicity, and central nervous system toxicity. If an overdose is suspected, seek medical attention immediately.

Contraindications

Progenta Ee should not be used by people with previous allergy to gentamicin or other aminoglycosides. It should also be avoided in patients who suffer from neuromuscular diseases.

Use Direction

Progenta Ee should be taken exactly as prescribed by your doctor. Do not take more or less than the recommended dose, and do not stop taking gentamicin without consulting your doctor.

Storage Conditions

Progenta Ee should be stored in a cool, dry, dark place (preferably a refrigerator). Keep out of the reach of children and pets.

Volume of Distribution

The volume of distribution (Vd) for gentamicin is 0.36-0.6 liters/kg. This means that gentamicin is widely distributed throughout the body and can reach all body tissues.

Half Life

The half-life of gentamicin is 2-3 hours. This means that half of the drug will be eliminated from the body in 2-3 hours after administration.

Clearance

The clearance of gentamicin from the body is relatively rapid (3-5 mL/min/kg). Therefore, frequent dosing is necessary to maintain an effective therapeutic concentration.

Here you find in details version of Progenta Ee

Some Frequently Asked Questions About Progenta Ee

1. What is Progenta Ee?

Progenta Ee is an antibiotic used to treat a wide range of infections caused by certain bacteria.

2. How does Progenta Ee work?

Progenta Ee works by killing bacteria or preventing their growth. It does this by preventing the bacteria from making proteins that they need to survive and multiply.

3. What is Progenta Ee used to treat?

Progenta Ee is used to treat a wide range of infections caused by certain bacteria, including skin, urinary tract, ear, respiratory, and intra-abdominal infections.

4. Who should not take Progenta Ee?

People who are allergic to Progenta Ee or any other antibiotic in the aminoglycoside family should not take Progenta Ee.

5. What are the potential side effects of Progenta Ee?

Common side effects of Progenta Ee include nausea, vomiting, diarrhea, and rash. Other possible side effects include dizziness, hearing loss, and kidney damage.

6. What should I do if I experience a side effect from taking Progenta Ee?

Contact your healthcare provider immediately if you experience any side effects while taking Progenta Ee.

7. Is there an age limit to taking Progenta Ee?

Progenta Ee is safe to use in both adults and children, but dosage may vary depending on a person’s age and body weight.

8. Is it safe to use Progenta Ee while pregnant or breastfeeding?

Progenta Ee should only be used during pregnancy and breastfeeding if the potential benefits outweigh the risks. Contact your healthcare provider for more information.

9. How is Progenta Ee taken?

Progenta Ee is usually taken by mouth in tablet or capsule form, or as an intravenous or intramuscular injection.

10. How often should Progenta Ee be taken?

The frequency and duration of treatment with Progenta Ee depend on the type and severity of the infection being treated. Your healthcare provider can provide specific dosing instructions.

11. What happens if I miss a dose of Progenta Ee?

If you miss a dose of Progenta Ee, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule.

12. What should I avoid while taking Progenta Ee?

You should avoid driving or operating hazardous machinery while taking Progenta Ee as it may cause dizziness. Alcohol should also be avoided while taking Progenta Ee.

13. Is Progenta Ee safe for long-term use?

Progenta Ee should not be used for long-term treatment unless absolutely necessary, as it may lead to the development of resistance to the antibiotic.

14. Is a prescription required for Progenta Ee?

Yes, a prescription is required for Progenta Ee.

15. Can Progenta Ee be bought over-the-counter?

No, Progenta Ee is a prescription-only medication and cannot be bought over-the-counter.

16. Is Progenta Ee available as a generic?

Yes, Progenta Ee is available as a generic medication.

17. Is Progenta Ee covered by insurance?

Yes, most insurance plans cover Progenta Ee.

18. How long does Progenta Ee take to work?

Progenta Ee usually starts to take effect within a few hours of taking the dose. It is important to complete the entire course of treatment prescribed by your healthcare provider.

19. Is Progenta Ee safe for children?

Yes, Progenta Ee is safe to use in both adults and children, but doses may vary depending on a person’s age and body weight.

20. Does Progenta Ee interact with any other drugs?

Progenta Ee can interact with other drugs and supplements, so it is important to tell your healthcare provider about all medications and supplements that you are taking before taking Progenta Ee.

21. Should I take Progenta Ee with food or on an empty stomach?

Progenta Ee should be taken with food to reduce the risk of stomach upset or nausea.

22. Can I drink alcohol while taking Progenta Ee?

No, drinking alcohol while taking Progenta Ee can increase the risk of side effects.

23. What should I do if I experience severe stomach pain or vomiting while taking Progenta Ee?

Contact your healthcare provider immediately if you experience severe stomach pain or vomiting while taking Progenta Ee.

24. Can I take Progenta Ee with other antibiotics?

No, taking Progenta Ee with other antibiotics can lead to serious side effects. Tell your healthcare provider about all the medications and supplements you are taking before starting Progenta Ee.

25. Is it safe to take Progenta Ee while breastfeeding?

Progenta Ee should only be used during breastfeeding if the potential benefits outweigh the risks. Talk to your healthcare provider for more information.

26. Is Progenta Ee safe to use if I have a pre-existing medical condition?

Progenta Ee should only be used if the potential benefits outweigh the risks to the patient. Talk to your healthcare provider if you have a pre-existing medical condition before taking Progenta Ee.

27. Is Progenta Ee safe for people with kidney or liver disease?

Progenta Ee can cause damage to the kidneys or liver if taken in high doses or for extended periods of time. People with kidney or liver disease should talk to their healthcare provider before taking Progenta Ee.

28. What should I do if I experience hearing loss while taking Progenta Ee?

Contact your healthcare provider immediately if you experience any hearing loss while taking Progenta Ee.

29. Can Progenta Ee be used to treat bacterial infections in the eye?

Progenta Ee can be used to treat bacterial infections in the eye, but it should not be used to treat viral or fungal infections.

30. Can Progenta Ee be used to treat sexually transmitted infections (STIs)?

Yes, Progenta Ee can be used to treat some STIs such as gonorrhea and chlamydia.