Pidgrel

Pidgrel Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Pidgrel is a brand name. Its generic name is Clopidogrel.

Introduction

Pidgrel is an antiplatelet medication used to reduce the risk of stroke and cardiovascular deaths in people with heart disease. It is also used to reduce the risk of recurring chest pain caused by a heart attack. Pidgrel works by preventing platelets in the blood from sticking together and forming clots that can lead to a stroke or heart attack.

Uses for

Pidgrel is used to reduce the risk of stroke and cardiovascular death in people with existing heart disease or who are at high risk of developing heart disease. It is also used to reduce the risk of recurrent chest pain caused by a heart attack. It is not used to treat chest pain when it occurs.

Mechanism of Action

Pidgrel prevents platelets from sticking together and forming clots that can lead to a stroke or heart attack. It does this by inhibiting the action of an enzyme called platelet activating factor (PAF). By blocking PAF, clopidogrel prevents the platelets from clumping together, which reduces the risk of stroke and heart attack.

How Long Does It Take To Work?

Pidgrel usually begins to work within 1 week of starting treatment. However, it may take up to 4 weeks for the full benefits of the medication to be seen.

Absorption

Pidgrel is rapidly and completely absorbed from the gastrointestinal tract after oral administration. The maximum plasma concentration is achieved 1 to 2 hours after oral administration.

Route of Elimination

Pidgrel is eliminated primarily by the liver. It is metabolized by the cytochrome P450 enzymes CYP2C19 and CYP3A4 and excreted in the feces. A small amount is also excreted in the urine.

Dosage

Pidgrel is taken orally in tablet form. The usual adult dose is 75 mg once daily without regard to meals. Dosage may be increased to 150 mg daily in some patients. The dose should not exceed 150 mg per day. Your doctor may adjust your dose based on your blood work or other medications you are taking.

Administration

Pidgrel should be taken with food. Swallow the tablet whole with a full glass of water. Do not break, crush, or chew the tablet.

Side Effect

Common side effects of Pidgrel include headache, dizziness, nausea, vomiting, diarrhea, constipation, rash, and fatigue. More serious side effects may include anemia, pancreatitis, gingival bleeding, heart rhythm disturbances, and thrombocytopenia.

Toxicity

Pidgrel has an LD50 of 5500 mg/kg in rats. Toxicity is rare except in cases of accidental overdose or in patients with liver or kidney damage taking large doses.

Precaution

Patients taking Pidgrel should avoid consuming alcohol as it can increase the risk of bleeding. Other drugs that may interact with Pidgrel include aspirin, NSAIDs, and warfarin. Tell your doctor about any medications you are taking before taking Pidgrel.

Interaction

Pidgrel may interact with other medications, including aspirin, NSAIDs, and warfarin. Tell your doctor about any medications you are taking before taking Pidgrel.

Disease Interaction

Pidgrel may interact with certain diseases, such as liver or kidney damage. It is important to tell your doctor about any diseases you may have before taking Pidgrel.

Drug Interaction

Certain drugs can interact with Pidgrel, including aspirin, NSAIDs, and warfarin. Tell your doctor about any medications you are taking before taking Pidgrel.

Food Interactions

Pidgrel should be taken with food. Avoid unhealthy fats (including trans fats) as they may reduce the absorption of Pidgrel and lower its effectiveness. Grapefruit and grapefruit juice may interact with Pidgrel and should be avoided.

Pregnancy Use

Pidgrel is classified as a Pregnancy Category C medication, which means that it is not known if it can harm an unborn baby. It is important to tell your doctor if you are pregnant or suspect you are pregnant before taking Pidgrel.

Lactation Use

Pidgrel should not be taken by breastfeeding women. It is not known if clopidogrel is excreted in human milk and it is not recommended for use during breastfeeding.

Acute Overdose

An overdose of clopidogrel may cause bleeding, difficulty breathing, or dizziness. If you or someone you know has taken an overdose of clopidogrel, seek immediate medical attention.

Contraindication

Pidgrel should not be used in patients who are hypersensitive to it, in patients with active bleeding, or in pregnant or breastfeeding women. Pidgrel should also not be used in patients who are taking anticoagulants such as warfarin.

Use Direction

Pidgrel is an oral medication taken once daily without regard to meals. The usual adult dose is 75 mg once daily but your doctor may adjust your dose based on your blood work or other medications you are taking. Swallow the tablet whole with a full glass of water. Do not break, crush, or chew the tablet.

Storage Condition

Pidgrel should be stored at room temperature, away from heat and direct light. It should be tightly closed in a cool, dry place.

Volume of Distribution

The volume of distribution of clopidogrel is 11 liters.

Half Life

The half life of clopidogrel is approximately 7 hours.

Clearance

The clearance of clopidogrel is 11 liters/hour.

Here you find in details version of Pidgrel

Some Frequently Asked Questions About Pidgrel

What is Pidgrel?

Pidgrel is a medication used to reduce the risk of stroke and heart attack in people who are at high risk. It is an antiplatelet drug, meaning it helps to prevent blood clots, and is often prescribed in combination with aspirin.

Who should take Pidgrel?

Pidgrel is commonly prescribed to those with a history of heart attack, stroke, or peripheral artery disease. It may also be recommended for those who have recently had a stent inserted, or who have unstable angina. Your doctor can advise if Pidgrel is right for you.

How does Pidgrel work?

Pidgrel works by blocking platelets from clumping together and forming clots in the arteries. By reducing the formation of clots in the arteries, Pidgrel can help to prevent heart attack, stroke and other cardiovascular events.

What are the common side effects of Pidgrel?

The most common side effects of Pidgrel include headache, diarrhea, nausea, indigestion, stomach pain and constipation. If any of these symptoms persist or worsen, contact your doctor as soon as possible.

Can I drink alcohol while taking Pidgrel?

It is not recommended to drink alcohol while taking Pidgrel as it can increase the risk of side effects. Ask your doctor if it is safe for you to drink alcohol while taking Pidgrel.

When should I take Pidgrel?

Pidgrel is taken once daily, usually in the morning. It is important to take it at the same time each day to ensure it is effective and to help you remember to take it.

How long does it take for Pidgrel to work?

Pidgrel starts to work within a few hours of taking it. It may take up to two weeks for the full effects of the medication to be seen.

Can I take other medications while taking Pidgrel?

Always tell your doctor or pharmacist about any medications or supplements you are taking while taking Pidgrel. Some medicines may interact and cause serious side effects, so it is important to have your doctor check that it is safe to take other medications while Pidgrel.

Can women take Pidgrel?

Yes, women can take Pidgrel, but pregnant women should not take it as it may have adverse effects on the unborn baby. It is also important to tell your doctor if you are breastfeeding as Pidgrel may pass into breast milk and may harm a nursing baby.

What should I do if I forget to take my Pidgrel?

If you forget to take your Pidgrel, take it as soon as you remember and then take your next dose at the usual time. Do not take a double dose to make up for the missed dose.

What happens if I overdose on Pidgrel?

If you take more Pidgrel than prescribed, contact your doctor immediately or go to the emergency room. Overdosing on Pidgrel can cause serious side effects or death.

Does Pidgrel have any interactions with food or alcohol?

There are no known interactions between food and Pidgrel, but alcohol can increase the risk of adverse side effects. It is not recommended to drink alcohol while taking Pidgrel.

What are the most serious side effects of Pidgrel?

The most serious side effects of Pidgrel include difficulty breathing, signs of bleeding (nosebleeds, bleeding gums, blood in urine or stool), vision loss or changes, severe dizziness, fainting, or signs of an allergic reaction (hives, rash, itching, swelling). Seek immediate medical attention if you experience any of these symptoms.

Is there a generic form of Pidgrel available?

Yes, there is a generic form of Pidgrel available in the US. However, it is important to note that the generic forms may not have the same ingredients as the brand name version, and they may not be as effective. Talk to your doctor to find out more.

What is the cost of Pidgrel?

The cost of Pidgrel varies depending on the form and brand of the medication you choose. Talk to your doctor or pharmacist to find out the cost of your prescription.

Can I take Pidgrel with other medications?

Always tell your doctor or pharmacist about any medications or supplements you are taking while taking Pidgrel. Your doctor may need to adjust your dose of Pidgrel if you are taking other medications, and some medicines may interact and cause serious side effects, so it is important to have your doctor check that it is safe to take other medications while taking Pidgrel.

Can Pidgrel be used to treat other conditions?

No, Pidgrel should not be used for any condition other than those for which it is prescribed by your doctor. Do not take Pidgrel for any other purpose, and never give Pidgrel to someone else.

Does Pidgrel cause weight gain?

Weight gain is not a common side effect of Pidgrel, but it is possible. If you notice any changes in your weight while taking Pidgrel, contact your doctor.

Can I take over-the-counter medication while taking Pidgrel?

Always tell your doctor or pharmacist about any medications or supplements you are taking while taking Pidgrel. Some over-the-counter medicines may interact with Pidgrel and cause serious side effects, so it is important to have your doctor check that it is safe to take other medications while taking Pidgrel.

What should I do if I have an allergic reaction to Pidgrel?

If you experience any signs of an allergic reaction to Pidgrel, such as rash, itching, hives, swelling, or difficulty breathing, discontinue use and contact your doctor immediately.

Can I stop taking Pidgrel if I'm feeling better?

No, it is important to take Pidgrel as prescribed for the duration of your treatment. Do not stop taking the medication without first consulting your doctor, as it may cause an increased risk of stroke and heart attack.

Does Pidgrel cause hair loss?

Hair loss is not a common side effect of Pidgrel, but it is possible. If you notice unusual hair loss while taking Pidgrel, contact your doctor.

Can I take Pidgrel while pregnant?

No, it is not safe to take Pidgrel while pregnant as it may cause serious harm to the unborn baby. If you are pregnant, contact your doctor immediately.

Can I take Pidgrel if I have kidney or liver problems?

If you have kidney or liver problems, your doctor may need to adjust your dose of Pidgrel. Talk to your doctor before starting Pidgrel if you have any kidney or liver issues.

What should I do if I experience severe stomach pain while taking Pidgrel?

If you experience severe stomach pain while taking Pidgrel, contact your doctor immediately. Severe stomach pain can be a sign of bleeding, which can be serious.

Can I take Pidgrel if I have a history of bleeding disorders?

Pidgrel can increase the risk of bleeding, so it is important to tell your doctor if you have a history of bleeding disorders before taking Pidgrel. Your doctor can advise if it is safe for you to take this medication.

What should I do if I experience muscle weakness while taking Pidgrel?

If you experience muscle weakness while taking Pidgrel, contact your doctor immediately. Muscle weakness can be a sign of muscle breakdown, which can be serious.

Can I take Pidgrel if I'm breastfeeding?

Talk to your doctor before taking Pidgrel if you are breastfeeding. Pidgrel can pass into breast milk and it may harm a nursing baby. Your doctor can advise on whether or not it is safe for you to take Pidgrel while breastfeeding.

Can I take Pidgrel if I have diabetes?

Yes, you can take Pidgrel if you have diabetes, but your doctor may need to adjust your dose. It is important to tell your doctor if you have diabetes so they can ensure that Pidgrel is safe for you.

Does Pidgrel interact with other medications?

Pidgrel may interact with other medications, including prescription, over-the-counter and herbal medications. Always tell your doctor or pharmacist about any medications or supplements you are taking while taking Pidgrel. Some medicines may interact and cause serious side effects, so it is important to have your doctor check that it is safe to take other medications while taking Pidgrel.

How long should I take Pidgrel?

Your doctor will determine how long you should take Pidgrel. It is important to take Pidgrel for as long as prescribed in order to ensure it is effective. Do not stop taking Pidgrel without first consulting your doctor.

What is the usual dose of Pidgrel?

The usual dose of Pidgrel is 75mg once daily. Your doctor may prescribe a different dose if needed. Always follow your doctor's instructions when taking Pidgrel.

Can I take herbal supplements while taking Pidgrel?

Always tell your doctor or pharmacist about any medications or supplements you are taking while taking Pidgrel. Some herbal supplements may interact with Pidgrel and cause serious side effects, so it is important to have your doctor check that it is safe to take other medications while taking Pidgrel.

Can Pidgrel cause dizziness?

Dizziness is a common side effect of Pidgrel. If you experience severe or persistent dizziness, contact your doctor.

Does Pidgrel cause blurred vision?

Blurred vision is not a common side effect of Pidgrel, but it is possible. If you experience blurry vision while taking Pidgrel, contact your doctor.

Is Pidgrel effective in treating heart attack and stroke?

Pidgrel is an antiplatelet drug, meaning it helps to prevent blood clots. It can reduce the risk of heart attack and stroke in those who are at high risk. Your doctor can advise if Pidgrel is right for you.

Can Pidgrel cause skin rash?

Skin rash is not a common side effect of Pidgrel, but it is possible. If you experience a skin rash while taking Pidgrel, contact your doctor.