PDGF-2
PDGF-2 Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? PDGF-2 is a brand name. Its generic name is Becaplermin.
PDGF-2 Introduction
PDGF-2 is a recombinant human platelet derived growth factor (PDGF) indicated for the treatment of skin ulcers and chronic non-healing wounds due to diabetes. It is a form of skin medication, also known as a stenomer or biosynthetic. PDGF-2 encourages wound healing by stimulating new tissue growth, collagen formation, and improved circulation to the wound area. PDGF-2 is clinically proven to be effective in healing diabetic foot ulcers and pressure sores.PDGF-2 Uses
PDGF-2 is used to treat skin ulcers or chronic non-healing wounds, including diabetic foot ulcers and pressure sores. It works by stimulating the growth of new tissue and collagen, and improving circulation to the affected area. PDGF-2 is typically used in combination with traditional woundcare treatments, such as debridement, compression, and wound care, for optimal results.PDGF-2 Mechanism of Action
PDGF-2 works by stimulating the growth of new tissue and collagen in the wound area. This helps to promote healing of skin ulcers and chronic non-healing wounds. PDGF-2 works by binding to a receptor on the surface of cells located in the wound area. This binding triggers a cascade of biochemical signals which result in increased cell proliferation and collagen synthesis, increased levels of new blood vessels, and enhanced recruitment of cells necessary for wound repair.How Long Does it Take for PDGF-2 to Work?
The exact amount of time it takes for PDGF-2 to work depends on the severity of the wound and the individual patient's response. In general, PDGF-2 is typically used in combination with traditional woundcare treatments, such as debridement, compression, and wound care, which can take several weeks to months to be effective.PDGF-2 Absorption, Route of Elimination, Dosage, and Administration
PDGF-2 is available as a topical gel. It is applied to the affected area once a day by applying a thin film of the medication to the wound using a gloved finger. The dosage of PDGF-2 is determined by the size of the wound. PDGF-2 is typically used in combination with other wound care treatments, and should be applied for up to 8 weeks or until the wound is healed.PDGF-2 Side Effects
Common side effects of PDGF-2 include skin redness, pain, burning, irritation, itching, swelling, or a rash at the application site. If these side effects are severe or persistent, notify your healthcare provider.PDGF-2 Toxicity
PDGF-2 is generally safe and well-tolerated when used as directed. There is no known risk of overdose or toxicity when it is applied as directed.PDGF-2 Precaution and Interactions
It is important to tell your doctor or healthcare provider about all other medications you are taking, including any vitamins, herbs, or supplements. PDGF-2 may interact with some medications such as certain antimicrobials, immunosuppressants, and antineoplastic agents.PDGF-2 Disease Interaction, Drug Interaction, Food Interactions, Pregnancy Use, Lactation Use
PDGF-2 is not recommended for use during pregnancy or lactation due to the lack of available data on its safety. PDGF-2 is also not recommended for use with antineoplastic agents, immunosuppressants, or certain antimicrobials. PDGF-2 should not be taken with food or beverages.PDGF-2 Acute Overdose
There is no known risk of an acute overdose with PDGF-2.PDGF-2 Contraindication
PDGF-2 is contraindicated in patients with a known hypersensitivity to PDGF-2 or any of its components.PDGF-2 Use Directions
PDGF-2 should be applied once daily by applying a thin film of the medication to the affected area using a gloved finger. PDGF-2 should be used in combination with other wound care treatments and should be used for up to 8 weeks or until the wound is healed.PDGF-2 Storage Conditions
PDGF-2 should be stored at room temperature away from light and moisture. Do not freeze PDGF-2.PDGF-2 Volume of Distribution, Half Life, Clearance
The volume of distribution, half life, and clearance of PDGF-2 are not known.Here you find in details version of PDGF-2
Some Frequently Asked Questions About PDGF-2
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http://www.pharmgkb.org/drug/PA164749511,
http://www.rxlist.com/cgi/generic2/becapler.htm,
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https://en.wikipedia.org/wiki/Becaplermin,