Platelet-derived Growth Factor Beta Polypeptide

Platelet-derived Growth Factor Beta Polypeptide Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Platelet-derived Growth Factor Beta Polypeptide is a brand name. Its generic name is Becaplermin.

Platelet-derived Growth Factor Beta Polypeptide Introduction

Platelet-derived Growth Factor Beta Polypeptide is a recombinant human platelet derived growth factor (PDGF) indicated for the treatment of skin ulcers and chronic non-healing wounds due to diabetes. It is a form of skin medication, also known as a stenomer or biosynthetic. Platelet-derived Growth Factor Beta Polypeptide encourages wound healing by stimulating new tissue growth, collagen formation, and improved circulation to the wound area. Platelet-derived Growth Factor Beta Polypeptide is clinically proven to be effective in healing diabetic foot ulcers and pressure sores.

Platelet-derived Growth Factor Beta Polypeptide Uses

Platelet-derived Growth Factor Beta Polypeptide is used to treat skin ulcers or chronic non-healing wounds, including diabetic foot ulcers and pressure sores. It works by stimulating the growth of new tissue and collagen, and improving circulation to the affected area. Platelet-derived Growth Factor Beta Polypeptide is typically used in combination with traditional woundcare treatments, such as debridement, compression, and wound care, for optimal results.

Platelet-derived Growth Factor Beta Polypeptide Mechanism of Action

Platelet-derived Growth Factor Beta Polypeptide works by stimulating the growth of new tissue and collagen in the wound area. This helps to promote healing of skin ulcers and chronic non-healing wounds. Platelet-derived Growth Factor Beta Polypeptide works by binding to a receptor on the surface of cells located in the wound area. This binding triggers a cascade of biochemical signals which result in increased cell proliferation and collagen synthesis, increased levels of new blood vessels, and enhanced recruitment of cells necessary for wound repair.

How Long Does it Take for Platelet-derived Growth Factor Beta Polypeptide to Work?

The exact amount of time it takes for Platelet-derived Growth Factor Beta Polypeptide to work depends on the severity of the wound and the individual patient's response. In general, Platelet-derived Growth Factor Beta Polypeptide is typically used in combination with traditional woundcare treatments, such as debridement, compression, and wound care, which can take several weeks to months to be effective.

Platelet-derived Growth Factor Beta Polypeptide Absorption, Route of Elimination, Dosage, and Administration

Platelet-derived Growth Factor Beta Polypeptide is available as a topical gel. It is applied to the affected area once a day by applying a thin film of the medication to the wound using a gloved finger. The dosage of Platelet-derived Growth Factor Beta Polypeptide is determined by the size of the wound. Platelet-derived Growth Factor Beta Polypeptide is typically used in combination with other wound care treatments, and should be applied for up to 8 weeks or until the wound is healed.

Platelet-derived Growth Factor Beta Polypeptide Side Effects

Common side effects of Platelet-derived Growth Factor Beta Polypeptide include skin redness, pain, burning, irritation, itching, swelling, or a rash at the application site. If these side effects are severe or persistent, notify your healthcare provider.

Platelet-derived Growth Factor Beta Polypeptide Toxicity

Platelet-derived Growth Factor Beta Polypeptide is generally safe and well-tolerated when used as directed. There is no known risk of overdose or toxicity when it is applied as directed.

Platelet-derived Growth Factor Beta Polypeptide Precaution and Interactions

It is important to tell your doctor or healthcare provider about all other medications you are taking, including any vitamins, herbs, or supplements. Platelet-derived Growth Factor Beta Polypeptide may interact with some medications such as certain antimicrobials, immunosuppressants, and antineoplastic agents.

Platelet-derived Growth Factor Beta Polypeptide Disease Interaction, Drug Interaction, Food Interactions, Pregnancy Use, Lactation Use

Platelet-derived Growth Factor Beta Polypeptide is not recommended for use during pregnancy or lactation due to the lack of available data on its safety. Platelet-derived Growth Factor Beta Polypeptide is also not recommended for use with antineoplastic agents, immunosuppressants, or certain antimicrobials. Platelet-derived Growth Factor Beta Polypeptide should not be taken with food or beverages.

Platelet-derived Growth Factor Beta Polypeptide Acute Overdose

There is no known risk of an acute overdose with Platelet-derived Growth Factor Beta Polypeptide.

Platelet-derived Growth Factor Beta Polypeptide Contraindication

Platelet-derived Growth Factor Beta Polypeptide is contraindicated in patients with a known hypersensitivity to Platelet-derived Growth Factor Beta Polypeptide or any of its components.

Platelet-derived Growth Factor Beta Polypeptide Use Directions

Platelet-derived Growth Factor Beta Polypeptide should be applied once daily by applying a thin film of the medication to the affected area using a gloved finger. Platelet-derived Growth Factor Beta Polypeptide should be used in combination with other wound care treatments and should be used for up to 8 weeks or until the wound is healed.

Platelet-derived Growth Factor Beta Polypeptide Storage Conditions

Platelet-derived Growth Factor Beta Polypeptide should be stored at room temperature away from light and moisture. Do not freeze Platelet-derived Growth Factor Beta Polypeptide.

Platelet-derived Growth Factor Beta Polypeptide Volume of Distribution, Half Life, Clearance

The volume of distribution, half life, and clearance of Platelet-derived Growth Factor Beta Polypeptide are not known.

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