Panim Cr

Panim Cr Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Panim Cr is a brand name. Its generic name is Nimesulide.

Panim Cr

Panim Cr is a nonsteroidal anti-inflammatory drug (NSAID) indicated for pain relief, fever and inflammation associated with several inflammatory diseases. It was first introduced in clinical use in early 1990s. It is available in the form of tablets, orally disintegrating tablets, suspensions or syrups.

Uses For

Panim Cr is generally used for the relief of acute and chronic pain relief associated with various infections such as dental pain, dysmenorrhea (painful menstrual cramps),musculoskeletal conditions like arthritis, tendinitis, bursitis and acute gouty arthritis. It is also used for symptomatic relief of fever like spongy fever and recurrent fever.

Mechanism of Action

Panim Cr works by inhibiting the inflammatory enzyme, cyclooxygenase (COX). This enzyme is responsible for the production of prostaglandins which are necessary for the inflammatory process. By inhibiting this enzyme, COX-2 mediates the anti-inflammatory effects of Panim Cr.

How Long Does It Take to Work?

Panim Cr typically takes about 30 minutes to an hour to become effective. The onset of action varies among individuals depending on the type and intensity of the pain.

Absorption

Panim Cr is quickly and completely absorbed after oral administration. It reaches the peak serum level within 1-2 hours. The plasma half-life of Panim Cr is approximately 1 hour.

Route of Elimination

Panim Cr is mainly eliminated through the faecal route, with only a small fraction being eliminated through the urine.

Dosage

The recommended dose of Panim Cr is 10-25mg twice a day, with an increase of up to 50mg per dose after 3-5 days if required. The maximum daily dose should not exceed 100mg. It should be taken with food to reduce gastric irritation.

Administration

Panim Cr can be taken orally or rectally, depending on the form. It is available in the form of tablets, orally disintegrating tablets, suspensions or syrups for oral administration. It can also be administered intramuscularly, subcutaneously or intravenously.

Side Effect

Common side effects associated with Panim Cr use include nausea, vomiting, abdominal pain, headache, dizziness, rash, itching, dry mouth and increased risk of gastrointestinal bleeding and ulceration. Other rare but serious side effects include, insomnia, depression, anxiety, blurred vision, confusion, hallucination, anaphylaxis and liver injury.

Toxicity

The most severe toxic effect due to Panim Cr overdose is liver injury with prolonged use of high doses. Other toxicities that may occur due to overdose include gastrointestinal bleeding, convulsions, hypotension, shock, nephrotoxicity and respiratory depression.

Precaution

Panim Cr should be taken with caution in patients with pre-existing gastrointestinal bleeding, liver and kidney ailments. It should be used with caution in elderly and in children, as it has a higher risk of gastrointestinal bleeding in these patients. It should not be used in pregnant and breastfeeding women as it can affect the foetus or baby.

Interaction

Panim Cr can interact with other drugs like antiplatelet agents, high blood pressure medications, and cyclosporine. So, it should be taken with caution when taken with other medications. Also, it should be taken with caution in patients with allergy to other non steroidal anti-inflammatory drugs,and should not be taken if you are taking aspirin.

Disease Interaction

Panim Cr should be used with caution in patients with bleeding disorders, heart or kidney diseases, as it can cause a further increase in the risk of serious side effects. Also, it should not be used if you have a history of asthma, as it can trigger an asthma attack.

Drug Interaction

Panim Cr may interact with other medications like anticoagulants, aspirin, corticosteroids, antimalarials, lithium, aspirin, phenytoin, phenobarbital and warfarin. So, if you are taking any of these drugs, you should inform your doctor.

Food Interactions

Panim Cr should be taken with food to reduce stomach irritation. Alcohol should be avoided while using Panim Cr; as it can increase the risk of stomach bleeding.

Pregnancy Use

Panim Cr should not be used during pregnancy as it can affect the health of the baby or the mother. The risks associated with taking Panim Cr are more than the benefits during pregnancy. So, it is recommended to avoid taking Panim Cr during pregnancy.

Lactation Use

Panim Cr should not be used during lactation as it can get into the breast milk, which may affect the baby. Also, the risks associated with taking Panim Cr are more than the benefits during lactation.

Acute Overdose

Acute overdose of Panim Cr may lead to symptoms like nausea, vomiting, drowsiness, abdominal pain, dizziness, sweating, and confusion. Liver and kidney toxicity can also occur due to prolonged use or overdose. In case of acute overdose, immediate medical attention should be sought.

Contraindication

Panim Cr should not be used in patients with hypersensitivity to this drug, those with pre-existing liver, kidney, and heart diseases, and those with gastrointestinal bleeding or ulcers. It should also not be used in pregnant and breastfeeding women, and in patients taking aspirin.

Use Directions

Panim Cr should be administered as per the doctor’s advice. It should not be taken in excess of the recommended dose, and should be taken with food to reduce the risk of gastrointestinal side effects. It should also be stored at room temperature and should be kept away from direct sunlight.

Storage Condition

Panim Cr should be stored at room temperature away from direct sunlight and moisture. It should be kept out of reach of children and pets.

Volume of Distribution

The volume of distribution of Panim Cr is 0.3 L per kg.

Half Life

The half life of Panim Cr is 1 hour.

Clearance

The clearance of Panim Cr is 1.2 mL per minute per kg.

Here you find in details version of Panim Cr

Some Frequently Asked Questions About Panim Cr

What is Panim Cr?

Panim Cr is a non-steroidal anti-inflammatory drug (NSAID) used to treat pain, fever, and inflammation.

Who manufactures Panim Cr?

Panim Cr is manufactured and marketed by various pharmaceutical companies.

What are the uses of Panim Cr?

Panim Cr is used to treat symptoms of arthritis, menstrual cramps, and other types of pain. It is also used to reduce fever.

What are the side effects of Panim Cr?

Common side effects of Panim Cr include nausea, vomiting, diarrhea, stomach pain, indigestion, headache, dizziness, and rash. Serious side effects may include heart attacks, strokes, and kidney damage.

Is Panim Cr safe to use?

Panim Cr should only be used under the supervision of a medical doctor. It is important to follow all the instruction provided by your doctor.

How long should I take Panim Cr?

The duration of treatment with Panim Cr must be determined by your doctor. It should not be used longer than the recommended period.

Does Panim Cr interact with any other drugs?

Panim Cr may interact with other drugs, including certain antibiotics, blood thinners, diuretics, and medications for high blood pressure. It is important to tell your doctor about any medications you are taking before taking Panim Cr.

What are the warnings associated with Panim Cr?

Panim Cr should not be used in people with conditions such as asthma, bleeding or blood clotting problems, or heart problems. It is also not recommended for people who are pregnant or breastfeeding. It should be avoided in people with liver or kidney disease.

What is the dosage of Panim Cr?

The dosage of Panim Cr will depend on the condition being treated, your age, and other factors. It is important to follow your doctor’s instructions carefully when taking this medication.

What should I do if I miss a dose of Panim Cr?

If you miss a dose of Panim Cr, take it as soon as possible. Do not take two doses at the same time. If it is close to your next scheduled dose, skip the missed dose and continue with your regular schedule.

What should I do if I overdose on Panim Cr?

If you or someone else has overdosed on Panim Cr, seek immediate medical attention. Symptoms of an overdose may include nausea, vomiting, dizziness, and abdominal pain.

Can Panim Cr be used in children?

Panim Cr is not recommended for use in children under 12 years of age. If your child needs a pain reliever, speak to your doctor about alternative medications.

Is Panim Cr available over-the-counter?

No, Panim Cr is not available over-the-counter. It requires a prescription from your doctor.

Can I take Panim Cr with food?

Yes, it is recommended to take Panim Cr with food or a glass of milk. This will help reduce the risk of stomach upset.

Does Panim Cr cause drowsiness?

Yes, Panim Cr may cause drowsiness or dizziness. It is important to avoid activities that require mental alertness, such as driving or operating machinery, until you know how the medication affects you.

Can Panim Cr be taken with alcohol?

No, it is not recommended to mix Panim Cr with alcohol. Alcohol can increase the risk of side effects from this medication.

What should I avoid while taking Panim Cr?

You should avoid activities that require mental alertness, such as driving or operating machinery, until you know how Panim Cr affects you. It is also important to avoid taking other medications that could interact with Panim Cr, unless instructed by your doctor.

Can Panim Cr cause weight gain?

There is no evidence that Panim Cr causes weight gain. However, it is possible to gain weight while taking Panim Cr if you are not careful with your diet.

What should I do if I experience an allergic reaction to Panim Cr?

If you experience any signs of an allergic reaction, such as hives, difficulty breathing, or swelling of the face, lips, tongue, or throat, stop taking the medication and contact your doctor immediately.

What should I tell my doctor before taking Panim Cr?

Before starting treatment with Panim Cr, it is important to tell your doctor about any other medications you are taking, your medical history, and any allergies you may have.

What form of Panim Cr is available?

Panim Cr is available in tablet, capsule, and oral suspension form.

What is the generic name of Panim Cr?

The generic name of Panim Cr is Panim Cr.

Does Panim Cr cause constipation?

Yes, Panim Cr may cause constipation. If you experience constipation while taking Panim Cr, speak to your doctor about other medications that may reduce this side effect.

Should Panim Cr be taken with food?

It is recommended to take Panim Cr with food or a glass of milk to reduce the risk of stomach upset.

What if I forget to take my dose of Panim Cr?

If you forget to take a dose of Panim Cr, take it as soon as you remember. If it is close to your next scheduled dose, skip the missed dose and continue with your regular schedule.

Is it safe to take Panim Cr while pregnant?

No, it is not recommended for pregnant women to take Panim Cr. Speak to your doctor about alternative medications.

Does Panim Cr cause dehydration?

Dehydration may be a side effect of Panim Cr use. It is important to drink plenty of fluids while taking this medication.

Can Panim Cr lower blood pressure?

Yes, Panim Cr may lower blood pressure. If you are taking medications to lower your blood pressure, speak to your doctor before taking Panim Cr.

Can I take Panim Cr with other NSAIDs?

No, it is not recommended to take Panim Cr with other NSAIDs. Taking multiple NSAIDs could increase your risk of side effects.

Should I take Panim Cr with food or on an empty stomach?

It is recommended to take Panim Cr with food or a glass of milk to reduce the risk of stomach upset.

Can Panim Cr be crushed or split?

You may be able to crush or split Panim Cr tablets. However, it is important to check with your doctor before doing so.

What are the possible drug interactions with Panim Cr?

Panim Cr may interact with certain antibiotics, blood thinners, diuretics, and medications for high blood pressure. It is important to tell your doctor about any medications you are taking before taking Panim Cr.

Is it safe to use Panim Cr long-term?

No, it is not recommended to use Panim Cr long-term. Long-term use of Panim Cr may increase the risk of side effects.

Can Panim Cr be used to treat stomach ulcers?

No, Panim Cr is not recommended for treating stomach ulcers. Speak to your doctor about other medications that may be more effective.

Can I take ibuprofen and Panim Cr together?

No, it is not recommended to take ibuprofen and Panim Cr together. Taking multiple NSAIDs could increase your risk of side effects.

Can I take Panim Cr while breastfeeding?

No, it is not recommended for breastfeeding women to take Panim Cr. Speak to your doctor about alternative medications.

Does Panim Cr cause kidney damage?

Yes, long-term use of Panim Cr may increase the risk of kidney damage. It is important to use this medication only under the guidance of your doctor.

Can Panim Cr be used to treat fever?

Yes, Panim Cr is used to treat fever by reducing inflammation and reducing body temperature.

Can Panim Cr cause skin rash?

Yes, Panim Cr may cause a skin rash. If you experience any skin rash while taking Panim Cr, contact your doctor immediately.

Can Panim Cr be taken with antibiotics?

Yes, Panim Cr can be taken with certain antibiotics. However, it is important to tell your doctor about any medications you are taking before taking Panim Cr.

Does Panim Cr elevate liver enzymes?

Yes, long-term use of Panim Cr may cause elevated liver enzymes. It is important to speak to your doctor if you experience any signs of liver problems while taking this medication.

Can I buy Panim Cr online?

No, Panim Cr is not available to buy online. It requires a prescription from your doctor.