Pandolac XR

Pandolac XR Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Pandolac XR is a brand name. Its generic name is Etodolac.

Pandolac XR Introduction

Pandolac XR is a prescription medication used to treat mild to moderate pain, arthritis, and gout. It is in the family of medications called Nonsteroidal Anti-inflammatory Drugs (NSAIDs). Pandolac XR works by blocking the action of certain natural substances in the body to reduce pain and swelling. It is available as a 400 mg, 500 mg, and 600 mg tablet.

Uses for Pandolac XR

Pandolac XR is commonly used to treat pain caused by rheumatoid arthritis, osteoarthritis, gout, ankylosing spondylitis, and other musculoskeletal conditions. It can also be used to reduce fever and treat menstrual pain. Pandolac XR may help reduce joint pain, stiffness, and swelling, but it does not cure the underlying condition.

Mechanism of Action

Pandolac XR works by blocking the action of certain natural substances in the body, such as prostaglandins. Prostaglandins help your body regulate pain, inflammation, and fever. By blocking the action of prostaglandins, etodolac can help reduce pain, inflammation, and fever.

How Long Does It Take to Work?

It usually takes a few days for etodolac to start working. Most people feel some relief after 3-7 days, although it may take longer for some people. It is important to take etodolac exactly as prescribed by your doctor. Do not stop taking etodolac before the course is finished, even if you start to feel better.

Absorption

Pandolac XR is rapidly and completely absorbed from the gastrointestinal tract. Its maximum plasma concentration is reached 1-2 hours after oral administration.

Route of Elimination

Pandolac XR is eliminated mostly through the kidneys by active renal secretion and passive glomerular filtration. Some of the drug is also eliminated through the bile.

Dosage

The usual dosage of etodolac for adults is 200-400mg taken orally four times a day. The maximum daily dosage should not exceed 2,400mg. It is usually taken with food to prevent stomach upset. It is important to take etodolac exactly as prescribed by your doctor. Do not exceed the prescribed dosage.

Administration

Pandolac XR should be taken orally with or without food, usually four times a day, or as directed by your doctor. Swallow the tablets whole with a full glass of water.

Side Effect

The most common side effects of etodolac are nausea, stomach pain, heartburn, vomiting, diarrhea, gas, dizziness, drowsiness, headache, blurred vision, rash, itching, and increased or decreased blood pressure. Less common side effects include swelling, chest pain, and shortness of breath. Contact your doctor immediately if you experience any of these side effects.

Toxicity

The most serious side effect of etodolac is liver damage. Signs of liver damage include dark urine, yellowing of the skin or eyes, nausea, vomiting, stomach pain, and loss of appetite. Severe allergic reactions, which may be life-threatening, have also been reported. Contact your doctor immediately if you experience any of these side effects.

Precaution

Before taking etodolac, tell your doctor if you have or have ever had any medical conditions, especially kidney or liver problems. Also tell your doctor if you are pregnant, breastfeeding, or if you drink alcohol. Pandolac XR may not be appropriate for people with certain medical conditions, and should only be taken with caution.

Interaction

Pandolac XR can interact with other medications, vitamins, and herbs. Tell your doctor about all the medications and supplements you are taking before starting etodolac, so they can monitor for drug interactions. Do not start or stop any medication without talking to your doctor first.

Disease Interaction

People with certain medical conditions may have an increased risk of experiencing serious side effects when taking etodolac. These conditions include kidney or liver disease, asthma, bleeding or clotting disorders, high cholesterol, heart disease, hypertension, and diabetes. People who have had a stroke or a seizure or who drink more than 3 alcoholic beverages per day should not take etodolac.

Drug Interaction

Pandolac XR can interact with certain medications, including blood thinners, lithium, diuretics, corticosteroids, ACE inhibitors, and antifungal medication. If you are taking any of these medications, talk to your doctor or pharmacist before starting etodolac. Your doctor may need to adjust your dose or monitor you closely for side effects.

Food Interactions

Pandolac XR can interact with certain foods. These include alcohol, caffeine, and spicy, salty, or sugary foods. It is important to follow your doctor’s instructions regarding diet and medication.

Pregnancy Use

Pandolac XR should only be used during pregnancy if the potential benefit justifies the potential risk to the fetus. It is not recommended for use during the first and last trimester of pregnancy. Talk to your doctor if you are pregnant or planning to become pregnant while taking etodolac.

Lactation Use

It is not known if etodolac is excreted into breast milk. If you are breastfeeding while taking etodolac, talk to your doctor about the risks and benefits.

Acute Overdose

If you take too much etodolac, seek medical attention immediately. Symptoms of overdose can include nausea, vomiting, stomach pain, dizziness, drowsiness, confusion, shortness of breath, rapid heartbeat, and loss of consciousness.

Contraindication

Pandolac XR is contraindicated in people who have had a hypersensitivity reaction to it or any other NSAID in the past. It is also contraindicated in people with a history of gastrointestinal bleeding or other active gastrointestinal diseases, or those taking anticoagulants.

Use Direction

Pandolac XR should be taken exactly as prescribed by your doctor. Do not take more or less than the recommended dose. It may take a few days for etodolac to start working, so be sure to take it for the full course of treatment prescribed by your doctor.

Storage Condition

Pandolac XR should be stored at room temperature and in a dry place away from light and moisture. Keep out of reach of children and pets.

Volume of Distribution

The volume of distribution of etodolac is 0.36 L/kg.

Half Life

The half-life of etodolac is approximately 12 hours.

Clearance

The clearance of etodolac is 0.72 mL/min/kg.

Here you find in details version of Pandolac XR

Some Frequently Asked Questions About Pandolac XR

What is Pandolac XR?

Pandolac XR is a nonsteroidal anti-inflammatory drug (NSAID) used for the treatment of moderate to severe pain, fever, and inflammation. It is marketed as Lodine in the US, and as Etopan, Etopan XL, and Etogesic in India.

What is the dosage of Pandolac XR?

Pandolac XR comes in several different dosages. The dosage depends on the indication, but most commonly etodolac is comfortably taken as one to two tablets of 200-400mg twice daily.

What is the mechanism of action of Pandolac XR?

Pandolac XR works by inhibiting the body's production of certain key chemical mediators that trigger inflammation. It does this by blocking the enzyme cyclooxygenase (COX), which is responsible for producing prostaglandins, one of the primary mediators involved in the inflammatory response.

How long does it take for Pandolac XR to work?

It can take anywhere from 1-2 hours after taking a dose of etodolac for it to start working. The effects can last up to 8 hours.

What are the side effects of Pandolac XR?

Common side effects associated with taking etodolac include nausea, loss of appetite, stomach pain, heartburn, bloating, gas, constipation, and headache. Other more serious side effects may include ringing in the ears, swelling, weight gain, confusion, unusual fatigue or weakness, and shortness of breath.

Can I take other medications while taking Pandolac XR?

It is generally recommended to avoid taking other medications that have similar effects, such as ibuprofen, aspirin, naproxen, or other NSAIDs, while taking etodolac. Before taking any other medications, check with your doctor or pharmacist to make sure it is safe to do so.

What are the warnings associated with Pandolac XR?

Pandolac XR should not be taken by those who are allergic to aspirin or other NSAIDs. It should also not be taken by pregnant women or those who are currently taking blood thinners or who have a history of stroke. Tell your doctor about any other medications you are currently taking before taking etodolac. If you experience any serious side effect while taking etodolac, seek medical attention immediately.

Is Pandolac XR a controlled substance?

No, Pandolac XR is not a controlled substance, but it is only available with a prescription from a doctor.

What does Pandolac XR treat?

Pandolac XR is used to treat moderate to severe pain, fever, and inflammation. It may be used to treat acute and long-term pain associated with inflammation, such as joint and muscle pain, arthritis, and back pain. It may also be used to treat period pain.

Should Pandolac XR be taken with food or on an empty stomach?

Pandolac XR is usually taken with food or milk to reduce the potential for skin reactions and upset stomach. It is usually taken in divided doses several times throughout the day.

How should Pandolac XR be stored?

Pandolac XR should be stored at room temperature, away from excess heat and moisture. Keep the medication in its original container, tightly closed when not in use.

Is etodolac safe during breastfeeding?

It is generally not recommended to take etodolac while breastfeeding as it is not known if etodolac passes into breast milk. Talk to your doctor about other options.

Can I take Pandolac XR with ibuprofen?

No, it is not recommended to take Pandolac XR with ibuprofen or any other nonsteroidal anti-inflammatory drugs (NSAIDs). Taking two different NSAIDs increases your risk of bleeding or other serious side effects.

How long can I take Pandolac XR for?

It is recommended to take Pandolac XR for short-term treatment of acute pain and inflammation. The duration of taking Pandolac XR will depend on your condition and how you respond to the medication. Your doctor will be able to advise on the best course of treatment.

Can etodolac cause heartburn?

Yes, one of the possible side effects of Pandolac XR is heartburn. If you experience persistent heartburn while taking Pandolac XR then consult your doctor.

How quickly does etodolac start working?

Pandolac XR usually starts to work within 1-2 hours after taking a dose. The effects can last up to 8 hours.

Is etodolac an over-the-counter drug?

No, Pandolac XR is only available with a prescription from a doctor.

Will I become addicted to Pandolac XR?

No. It is not possible to become addicted to Pandolac XR. However, it is important to only take it as directed by your doctor to prevent any unwanted side effects.

What is the maximum dosage of Pandolac XR?

The maximum dosage of Pandolac XR is 600mg per day, and should not be exceeded. Speak to your doctor or pharmacist for advice about the best dosage for you.

What symptoms can Pandolac XR help with?

Pandolac XR is used to treat moderate to severe pain, fever, and inflammation. It may be used to treat acute and long-term pain associated with inflammation, such as joint and muscle pain, arthritis, and back pain. It may also be used to treat period pain.

What are the most common side effects of Pandolac XR?

The most common side effects associated with taking etodolac include nausea, loss of appetite, stomach pain, heartburn, bloating, gas, constipation, and headache. If you experience any of these side effects while taking etodolac, contact your doctor.

Can I drink alcohol while taking Pandolac XR?

No, it is not recommended to drink alcohol while taking Pandolac XR as it may increase your risk of developing stomach ulcers or other side effects. Talk to your doctor or pharmacist if you are unsure.

Does Pandolac XR interact with other medications?

Yes, Pandolac XR may interact with certain medications, including blood thinners, lithium, and corticosteroids. It is important to tell your doctor about all medications you are taking before starting Pandolac XR.

Is Pandolac XR safe for seniors?

Yes, Pandolac XR is generally safe for seniors. However, talk to your doctor before taking it to make sure that it is safe for you, and to determine the best dosage.

Can Pandolac XR be used to treat cold symptoms?

No, Pandolac XR is not used to treat cold symptoms, as it is an anti-inflammatory drug and not an antiviral or antibiotic. Speak to your doctor about the best over-the-counter or prescription options for treating cold symptoms.

Can Pandolac XR be taken with acetaminophen?

Yes, Pandolac XR can be taken with acetaminophen. However, it is important to talk to your doctor about all medications you are taking before starting treatment with Pandolac XR.

Can children take Pandolac XR?

No, Pandolac XR is not recommended for children due to the potential for serious side effects such as increased risk of stomach ulcers and kidney damage. Talk to your doctor or pharmacist for advice on the best course of treatment for your child.

Can Pandolac XR be used to treat gout?

Yes, Pandolac XR can be used to treat gout. However, it is important to talk to your doctor about all medications you are taking before starting treatment with Pandolac XR.

What are the active ingredients in Pandolac XR?

The active ingredient in Pandolac XR is etodolac. It may also contain inactive ingredients such as talc, carnauba wax, sugar, methylcellulose, polyethylene glycol, and gluten.

What is the best time of day to take Pandolac XR?

It is usually recommended to take etodolac twice daily, once in the morning and once in the evening. Taking etodolac with food or milk will also help to reduce the potential for skin reactions or stomach upset.

Does Pandolac XR come in a generic form?

Yes, Pandolac XR is available in a generic form. Talk to your doctor or pharmacist for advice about the best form of etodolac for you.

Can I take Pandolac XR while pregnant?

No, it is not recommended to take Pandolac XR while pregnant due to the potential for serious side effects for both mother and baby. Speak to your doctor for advice about other options.

How long does it take for Pandolac XR to leave the body?

It takes approximately 4-6 hours for Pandolac XR to be completely eliminated from the body. However, this can vary depending on individual factors.

Does Pandolac XR cause drowsiness?

Yes, Pandolac XR can cause drowsiness in some people. If you experience any drowsiness while taking Pandolac XR, it is important to avoid activities such as driving or operating machinery until you know how it affects you.

What is the discreet dose of etodolac?

The recommended dose of etodolac will depend on the condition being treated and the individual. The usual dose for adults is one to two tablets of 200-400mg taken twice daily or as instructed by your doctor.

Is etodolac a blood thinner?

No, Pandolac XR is not a blood thinner. However, it is important to tell your doctor if you are taking any blood thinning medications before taking etodolac.

Can I take Pandolac XR for a headache?

No, it is not recommended to take Pandolac XR for headache, as it is an anti-inflammatory drug and not designed specifically to treat headache pain. Speak to your doctor for advice about other treatments for headache.

Can Pandolac XR cause constipation?

Yes, one of the common side effects of Pandolac XR is constipation. If you experience persistent constipation while taking Pandolac XR then consult your doctor.

Can I take Pandolac XR for toothache?

No, Pandolac XR should not be taken for toothache, as it is not specifically designed to treat dental pain. Speak to your doctor or dentist for advice about other treatments for toothache.

What is the difference between etodolac and ibuprofen?

Pandolac XR and ibuprofen are both nonsteroidal anti-inflammatory drugs (NSAIDs) used to treat pain and inflammation. However, etodolac is weaker than ibuprofen, and has a slightly longer duration of action. It is important to talk to your doctor about the best treatment for your condition.

What happens if I take too much Pandolac XR?

Taking too much etodolac can cause serious side effects, including stomach ulcers, nausea, vomiting, dizziness, drowsiness, and kidney damage. If you experience any of these symptoms seek medical attention immediately.

Can I take Pandolac XR for a cold?

No, Pandolac XR is not used to treat colds, as it is an anti-inflammatory drug and not an antiviral or antibiotic. Speak to your doctor about the best over-the-counter or prescription options for treating cold