Orciprenalinum
Orciprenalinum Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Orciprenalinum is a brand name. Its generic name is Orciprenaline.
Introduction
Orciprenalinum, also known as metaproterenol sulfate, is a β2-adrenergic agonist used to treat asthma, bronchitis, chronic obstructive pulmonary disease (COPD) and other respiratory ailments. It is an inhaled medication, and is available in the form of a metered-dose inhaler (MDI), nebulizer solution, or orally inhaled tablets or capsules.
Uses For
Orciprenalinum is used to prevent and treat the symptoms of conditions involving narrowed or constricted airways, such as asthma, bronchitis and COPD. It is used to prevent and reduce the frequency and severity of acute asthma attacks, as well as for the treatment of exercise-induced bronchospasm (EIB). Orciprenalinum is also used to prevent and treat breathlessness in patients with COPD.
Mechanism of Action
Orciprenalinum works by stimulating the β2-adrenergic receptors in the lungs. This causes the smooth muscles in the lungs to relax, resulting in widening of the airways and increased airflow. Orciprenalinum also reduces airway swelling and mucus production, which help improve airflow in the lungs.
How Long Does It Take to Work?
The effects of Orciprenalinum usually begin within minutes of taking an inhaled dose, and the maximum effect is usually seen within 15-30 minutes.
Absorption
Inhaled Orciprenalinum is rapidly and completely absorbed from the lungs. Inhaled doses are also rapidly eliminated from the body, usually within an hour.
Route of Elimination
Orciprenalinum is rapidly eliminated from the body, mainly through the kidneys. An inactive metabolite is also formed and eliminated in the feces.
Dosage
The recommended dosage of Orciprenalinum varies depending on the specific indication, as well as individual factors. In general, the usual dose for adult and pediatric patients aged 12 and over is the equivalent of 3-6 inhalations of an MDI, or 0.15-0.3 mg orally inhaled as tablets or capsules, every 4-6 hours as needed, up to a maximum cumulative daily dose of 12 inhalations or 0.6 mg.
Administration
Orciprenalinum is available in the form of a metered-dose inhaler (MDI), nebulizer solution, or orally inhaled tablets or capsules. It is important to carefully follow the instructions given by your healthcare provider when using Orciprenalinum.
Side Effects
Common side effects of Orciprenalinum include headaches, nausea and dizziness. Other side effects may include throat irritation, muscle cramps, increased heart rate and tremor. Severe side effects of Orciprenalinum include chest pain, wheezing, and an irregular heartbeat.
Toxicity
The toxic effects of Orciprenalinum are not fully known. However, overdoses may lead to serious side effects such as severe nausea and vomiting, tremors, confusion, muscle cramps, pain in the chest or throat, and a rapid or irregular heartbeat.
Precaution
Before taking Orciprenalinum, inform your healthcare provider if you are allergic to any of its ingredients, or if you are taking any other medications, including over-the-counter drugs. Do not use Orciprenalinum if you are pregnant, planning a pregnancy, or breastfeeding, as it may harm an unborn or nursing child.
Interaction
Orciprenalinum can interact with other medications and supplements, such as non-selective β-blockers, corticosteroids, and certain antipsychotic medications. Be sure to tell your healthcare provider about all medications and supplements you are taking before using Orciprenalinum.
Disease Interaction
Orciprenalinum can worsen certain medical conditions, such as diabetes, heart conditions, hypertension, and thyroid problems. Tell your healthcare provider about any existing medical conditions you have before taking Orciprenalinum.
Drug Interaction
Orciprenalinum may interact with certain drugs, such as non-selective β-blockers, corticosteroids, and certain antipsychotic medications. It is important to tell your healthcare provider about any other medications you are taking to avoid any potential drug interactions.
Food Interactions
Food does not interact with Orciprenalinum. However, it is important to follow any dietary instructions given by your healthcare provider.
Pregnancy Use
Orciprenalinum should not be used during pregnancy as it may harm an unborn baby. If you are pregnant or plan to become pregnant, discuss the risks and benefits of taking Orciprenalinum with your healthcare provider.
Lactation Use
Orciprenalinum should not be used by breastfeeding women. If you are breastfeeding or plan to breastfeed, discuss the risks and benefits of taking Orciprenalinum with your healthcare provider.
Acute Overdose
The signs and symptoms of an acute overdose of Orciprenalinum include nausea and vomiting, tremors, confusion, muscle cramps, pain in the chest or throat, and a rapid or irregular heartbeat. If you experience any of these symptoms, seek medical attention immediately.
Contraindication
Orciprenalinum is contraindicated in patients with known hypersensitivity to any of its ingredients, the use of monoamine oxidase inhibitors (MAOIs), or who have suffered a heart attack in the past 14 days. It is also contraindicated in patients with severe bronchospasm, tachyarrhythmias or severe CAD.
Use Direction
Carefully follow the instructions given by your healthcare provider when using Orciprenalinum. Do not exceed the recommended dose, as this may increase the risk of side effects.
Storage Condition
Store Orciprenalinum at room temperature, away from heat, light, and moisture. Do not freeze or store in direct sunlight.
Volume of Distribution
The volume of distribution of Orciprenalinum is not known.
Half-Life
The half-life of Orciprenalinum is not known.
Clearance
The clearance of Orciprenalinum is not known.
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