Optafenac

Optafenac Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Optafenac is a brand name. Its generic name is Nepafenac.

Optafenac Introduction

Optafenac is a non-steroidal anti-inflammatory drug (NSAID) indicated for the treatment of inflammation and pain associated with ocular surgery. It is also approved for the treatment of postoperative inflammation and for the symptomatic treatment of pain associated with cataract extraction.

Uses for Optafenac

The primary uses for Optafenac are the prevention and treatment of postoperative inflammation and pain associated with ocular surgery. It is also used for the treatment of conditions such as iritis, chorioretinitis, and macular edema, as well as complications related to cataract extraction.

Mechanism of Action of Optafenac

Optafenac works by inhibiting the activity of cyclooxygenase (COX)-1 and COX-2, two enzymes involved in the body’s production of prostaglandins, substances that can cause inflammation, pain, and fever.

How Long does it Take for Optafenac to Work?

Optafenac typically begins to work within minutes, though its exact effects may vary depending on the condition being treated and the patient’s individual response.

Absorption of Optafenac

Optafenac is rapidly and well absorbed when applied to the eye. Its peak concentration in the eye is reached within 5 minutes after application.

Route of Elimination of Optafenac

Optafenac is rapidly metabolized in the ocular tissue and is primarily eliminated via the kidneys.

Dosage of Optafenac

Optafenac is available as an ophthalmic solution, 0.1% in a unit dose container for single use only. The recommended dosage is one drop in the affected eye three times a day, approximately 8 to 12 hours apart.

Administration of Optafenac

Optafenac should be applied to the affected eye in the form of an eye drop immediately before any type of ocular surgery. It should also be applied to the affected eye four times a day (approximately 8 to 12 hours apart) for up to two weeks after the surgery. Clean your hands and the affected eye with warm water and a mild soap before applying the drops. Apply gentle pressure to the inside corner of the eye (near the nose) for one to two minutes to prevent the medication from entering the tear duct and entering the rest of the body.

Side Effects of Optafenac

The most common side effects of Optafenac include: eye pain, itching, redness, increased intraocular pressure, and eye discharge. Less common side effects may include a allergic reaction, eye infection, blurred vision, increased sensitiviy to light, and dry eyes.

Toxicity of Optafenac

Optafenac is generally considered to be safe and well-tolerated. However, long-term use may lead to higher systemic absorption, and consequently, higher risk of serious adverse events.

Precaution of Optafenac

Optafenac should be used cautiously in patients with a known history of bleeding disorders, high blood pressure, or cardiac or renal disease. Patients should inform their physician of any concomitant medication they are taking before using Optafenac.

Interaction of Optafenac

Optafenac is known to interact with certain drugs including Vitamin C, anticoagulants, and diuretics. Optafenac may also interact with other NSAIDs, corticosteroids, and antibiotic medications.

Disease Interactions with Optafenac

Optafenac may interact with certain diseases, including bleeding disorders, high blood pressure, and renal or cardiac diseases. As Optafenac may cause increased systemic absorption, caution should be exercised when used in these patients.

Drug Interactions with Optafenac

Optafenac may interact with certain drugs, including anticoagulants, diuretics, Vitamin C, NSAIDs, and corticosteroids. It is important to tell your doctor about all medications you are taking before using Optafenac.

Food Interactions with Optafenac

Optafenac is not known to interact with any dietary foods. However, it is important to follow all dietary instructions given by your doctor while using the medication.

Pregnancy Use of Optafenac

Optafenac should be used with caution in pregnant women, as its safety in such patients has not been established. Tell your doctor if you are pregnant before using the medication.

Lactation Use of Optafenac

Optafenac should not be used by women who are breastfeeding as it is not known if the medication is passed through breast milk. Talk to your doctor before using Optafenac if you are breastfeeding.

Acute Overdose of Optafenac

Optafenac is not generally associated with acute overdose. However, if an overdose is suspected, contact a healthcare provider immediately additional medical advice.

Contraindication of Optafenac

Optafenac is contraindicated in patients with known hypersensitivity to any component of the drug. It should also not be used in patients with a confirmed diagnosis of an eye infection, corneal abrasion, or dermatitis of the eye.

Use Directions of Optafenac

When using Optafenac, patients should follow their doctor’s directions and any printed instructions supplied with the medication. Before using the medication, the eye should be washed with warm water and a mild soap to remove any debris.

Storage Condition of Optafenac

Optafenac should be stored at room temperature away from direct light and moisture. The medication should also be kept out of the reach of children.

Volume of Distribution of Optafenac

The volume of distribution of Optafenac is not known.

Half Life of Optafenac

The half-life of Optafenac is approximately 4 hours.

Clearance of Optafenac

The clearance of Optafenac is not known.

Here you find in details version of Optafenac

Some Frequently Asked Questions About Optafenac

What is Optafenac?

Optafenac is a nonsteroidal anti-inflammatory (NSAID) eye drop used to treat the pain and swelling associated with cataract surgery. It works by blocking the production of certain naturally occurring substances in the body that cause inflammation.

How does Optafenac work?

Optafenac works by blocking the production of certain naturally occurring substances in the body that cause inflammation. It is the only NSAID approved to be used after cataract surgery.

Who can use Optafenac?

Optafenac is for use only in adults after cataract surgery. It should not be used in children.

How often should I take Optafenac?

Optafenac is typically used every 8 to 12 hours, starting one day before your cataract surgery and continuing until the eye doctor or surgeon tells you to stop. Be sure to follow all instructions from your eye doctor or surgeon when using Optafenac.

What are the possible side effects of Optafenac?

Common side effects of Optafenac include eye irritation or burning, redness of the eye, blurred vision, scratchiness in the eyes, and eye discharge. If you experience any of these side effects, talk to your doctor.

Are there any precautions to take while using Optafenac?

You should not use Optafenac if you are allergic to any of its ingredients. Be sure to tell your doctor or eye doctor if you have a history of allergies, asthma, or any other serious medical conditions. Do not use more or less than recommended when taking Optafenac.

Can I use other eye medications in combination with Optafenac?

You should not use any NSAIDs, antibiotics, corticosteroids, or other prescribed medications in combination with Optafenac without first talking to your doctor. Additionally, do not use other eye drops while using Optafenac unless your doctor tells you to.

What should I do if I forget to take my dose of Optafenac?

If you miss a dose of Optafenac, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for the missed dose.

Should I avoid certain foods or drinks while using Optafenac?

No, there are no foods or drinks that you need to avoid while using Optafenac. However, you should not drink alcohol while using Optafenac as it can increase the risk of stomach bleeding.

Is there an alternative to Optafenac?

No, there is currently no alternative for Optafenac. However, your doctor may be able to prescribe you a similar medication that is more suitable for your condition.

What should I do if my eye irritation gets worse?

If your eye irritation gets worse while using Optafenac, talk to your doctor or eye doctor immediately as they may need to adjust your dose or switch you to a different medication.

Can I wear contacts while taking Optafenac?

No, it is recommended that you avoid wearing contacts while taking Optafenac. Optafenac may cause eye irritation or burning that could make wearing contacts uncomfortable.

Can Optafenac be used for pain or discomfort in my eye caused by allergies?

No, Optafenac is not recommended for the relief of pain or discomfort caused by allergies. You should consult your doctor to determine the best course of treatment for your allergy-related eye symptoms.

Is there any scientific evidence to support the use of Optafenac?

Yes, studies have shown that Optafenac may reduce pain and swelling associated with cataract surgery. Additionally, studies have also found that Optafenac may improve vision after cataract surgery.

What should I do if I experience an allergic reaction to Optafenac?

If you experience any signs of allergic reaction to Optafenac such as hives, difficulty breathing, or swollen eyes, you should immediately stop using Optafenac and seek medical attention.

Are there any foods or medications that interact with Optafenac?

You should not use other NSAIDs, antibiotics, corticosteroids, or other prescribed medications in combination with Optafenac without first talking to your doctor. Additionally, certain other medications such as oral corticosteroids, diuretics, and dihydroergotamine can also interact with Optafenac, so make sure to tell your doctor about all the medications you are taking.

Can I take Optafenac if I'm pregnant or breastfeeding?

No, Optafenac should not be used in pregnant or breastfeeding women unless explicitly directed to do so by a doctor. If you are pregnant or breastfeeding and need to take Optafenac, be sure to talk to your doctor about the potential risks.

Does Optafenac cause dry eye?

No, Optafenac does not typically cause dry eye. However, it may make existing dry eye symptoms worse, so tell your doctor if you are experiencing any dry eye symptoms before using Optafenac.

Does Optafenac cause drowsiness?

No, Optafenac does not typically cause drowsiness. However, if you experience any drowsiness after using Optafenac, you should talk to your doctor.

Can I wear eye makeup while using Optafenac?

Yes, you can wear eye makeup while using Optafenac. However, it is recommended to wait at least 15 minutes after applying Optafenac before applying makeup.

Can I go outside while using Optafenac?

Yes, you can go outside while using Optafenac. However, you should apply sunglasses to protect your eyes from the sun.

Can I swim while taking Optafenac?

Yes, you can swim while taking Optafenac. However, you should wear a swim cap to protect your eyes from the chlorine.

Can Optafenac be used for glaucoma?

No, Optafenac is not recommended for the treatment of glaucoma. You should consult your doctor to determine the best course of treatment for your glaucoma.

Can I take a shower or bath while using Optafenac?

Yes, you may take a shower or bath while using Optafenac. Just be sure to keep your eyes closed when showering or bathing to avoid getting Optafenac in your eyes.

Does Optafenac interact with any other drugs?

Yes, certain drugs such as oral corticosteroids, diuretics, and dihydroergotamine can interact with Optafenac, so be sure to tell your doctor about all the medications you are taking.

Will I experience any vision changes while taking Optafenac?

No, you should not experience any vision changes while taking Optafenac. However, if you do experience vision changes while taking Optafenac, you should talk to your doctor or eye doctor.

What should I do if my vision becomes blurred while using Optafenac?

If your vision becomes blurred while using Optafenac, you should talk to your doctor or eye doctor. Blurred vision is a possible side effect of Optafenac, and your doctor may need to adjust your dose or switch you to a different medication.

Can I use artificial tears while using Optafenac?

Yes, you can use artificial tears while using Optafenac. However, it is recommended to wait at least 15 minutes after applying Optafenac before using artificial tears.

Can I use eye drops containing preservatives while using Optafenac?

No, it is not recommended to use eye drops containing preservatives while using Optafenac. Preservatives can irritate the eyes, and could make using Optafenac uncomfortable.

Can I wear contact lenses while taking Optafenac?

No, it is recommended that you avoid wearing contact lenses while taking Optafenac. Optafenac may cause eye irritation or burning that could make wearing contacts uncomfortable.

Is there an age limit to using Optafenac?

Yes, Optafenac is for use only in adults after cataract surgery. It should not be used in children.

Will I need to use Optafenac for my entire cataract surgery recovery period?

No, you will not need to use Optafenac for your entire cataract surgery recovery period. Your doctor or eye doctor will determine when you can stop using Optafenac.

Can I use Optafenac if I have a history of epilepsy or seizure disorder?

No, it is not recommended to use Optafenac if you have a history of epilepsy or seizure disorder. Talk to your doctor before using any medications for pain or inflammation if you have a history of seizures or epilepsy.

Does Optafenac treat any other eye diseases?

No, Optafenac is not recommended for conditions other than pain and swelling associated with cataract surgery. You should consult your doctor to determine the best course of treatment for any other eye conditions.

Can my eye become infected while using Optafenac?

Yes, it is possible for your eye to become infected while using Optafenac. If you experience any signs of eye infection such as unusual pain, swelling, redness, or pus-like discharge, contact your doctor or eye doctor immediately.

Does Optafenac help to improve my vision?

Yes, studies have found that Optafenac may improve vision after cataract surgery. Additionally, Optafenac may also reduce pain and swelling associated with cataract surgery.

How long should I wait after using Optafenac before driving?

It is recommended to wait at least 15 minutes after applying Optafenac before driving. Optafenac may cause blurred vision, so it is important to give your eyes time to adjust before driving.

Can I use Optafenac if I have a history of stomach ulcers?

No, it is not recommended to use Optafenac if you have a history of stomach ulcers. Optafenac can irritate the stomach, and could make your ulcers worse. Talk to your doctor before using any medications for pain or inflammation if you have a history of stomach ulcers.

Can I get a prescription for Optafenac if I have an infection in my eye?

No, it is not recommended to use Optafenac if you have an infection in your eye. You should talk to your doctor immediately if you have an eye infection as you may need antibiotics or other medication to treat it.