Omnipaque 350

Omnipaque 350 Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Omnipaque 350 is a brand name. Its generic name is Iohexol.

Introduction

Omnipaque 350 is a low-osmolar contrast media used in X-ray imaging procedures. It is an ionic, non-ionic, water-soluble contrast medium used in radiography and computed tomography (CT) scans. It is also used to assist in the diagnosis of certain vascular diseases and other conditions.

Uses For

Omnipaque 350 is used to improve the quality of medical images and as a diagnostic aid to assist in the detection of abnormal tissues, blood vessels, or organs. It can also be used to provide information about the size, shape, location, and function of various organs and tissues.

Mechanism of Action

Omnipaque 350 works by decreasing the beam attenuation of X-ray radiation, thereby improving the visibility of target organs and tissues. The contrast agent also has a high radiolabeling efficiency, allowing it to bind to and accumulate in the target organs and tissues. This reduces the scatter radiation, which further increases image visibility.

How Long Does it Take to Work

Omnipaque 350 begins to work almost as soon as it is administered; however, the exact time it takes to reach peak contrast activity varies depending on the imaging procedure and the patient’s condition. In general, most CT and radiography scans take between 15-30 minutes to complete.

Absorption

Omnipaque 350 is rapidly absorbed into the bloodstream following intravenous administration. It is then taken up by the target organs and tissues and binds to and accumulates in them, allowing for high-quality images.

Route of Elimination

Omnipaque 350 is rapidly excreted in the urine following imaging procedures, with most of it being eliminated within 24 hours.

Dosage

Dosage for Omnipaque 350 depends on the imaging procedure and the patient's condition. In general, the recommended dose for a CT scan is between 4.4-66.6 milligrams per kilogram ( mg/kg ) of body weight. Parenteral administration requires injection through an intravenous line.

Administration

Omnipaque 350 must be administered via a parenteral route. It is typically administered intravenously either through a vein or through an infusion pump, depending on the patient’s condition and the imaging procedure.

Side Effects

Common side effects of Omnipaque 350 include nausea, vomiting, rash, itching, hives, and anaphylaxis. More serious side effects may include renal impairment, seizures, and cardiac arrest.

Toxicity

Omnipaque 350 has a low toxicity profile and is generally well tolerated. The most common adverse effect is nausea; however, it is generally mild and passes quickly.

Precautions

Omnipaque 350 should be used with caution in people with kidney disease, as it may worsen pre-existing renal problems. It also has the potential to interact with certain medications, so it is important to inform the doctor about all medications the patient is currently taking.

Interactions

Omnipaque 350 can interact with certain medications, including those that affect the kidneys and those that reduce blood pressure. It is important to tell the doctor about all medications the patient is currently taking to prevent any potential interactions.

Disease Interactions

Omnipaque 350 should be used with caution in people with kidney disease, as it may worsen pre-existing renal problems. It is also contraindicated in people with an allergy to contrast media, as it can cause anaphylaxis.

Drug Interactions

Omnipaque 350 can interact with certain medications, including those that affect the kidneys, those that reduce blood pressure, and those that slow or stop the heart. It is important to tell the doctor about all medications the patient is currently taking to prevent any potential interactions.

Food Interactions

Omnipaque 350 should not be taken with food. The imaging procedure should be completed before eating.

Pregnancy Use

Omnipaque 350 has not been adequately studied in pregnant women. As such, the doctor should weigh the risks and benefits before using Omnipaque 350 in pregnant women.

Lactation Use

Omnipaque 350 should be used with caution in breastfeeding women, as it can pass into breast milk and cause an allergic reaction in nursing infants.

Acute Overdose

An acute overdose of Omnipaque 350 may cause symptoms such as nausea, vomiting, dizziness, and confusion. Treatment depends on the severity of the symptoms and may include supportive measures.

Contraindications

Omnipaque 350 is contraindicated in people with an allergy to contrast media, as it can cause anaphylaxis. It should also be used with caution in people with kidney disease, as it may worsen pre-existing renal problems.

Use Direction

Omnipaque 350 should be used as directed by a doctor. The dose and timing should be determined based on the type of imaging procedure and the patient’s condition.

Storage Condition

Omnipaque 350 should be stored at room temperature in its original container. It should not be exposed to light or temperatures higher than 30°C (86°F).

Volume of Distribution

Omnipaque 350 has a volume of distribution of approximately 0.3 liters/L.

Half Life

The half-life of Omnipaque 350 is 2.4 hours.

Clearance

Omnipaque 350 is cleared from the body primarily through the kidneys. Its renal clearance is approximately 0.14 liters/hr/kg.

Here you find in details version of Omnipaque 350

Some Frequently Asked Questions About Omnipaque 350

##What is Omnipaque 350?

Omnipaque 350 is a contrast agent used in X-ray, computed tomography (CT), and magnetic resonance imaging (MRI) imaging procedures. It is a water-soluble, organic iodine-containing compound that is much safer than the traditional barium-based contrast agents.

##How Does Omnipaque 350 Work?

Omnipaque 350 works by absorbing X-rays or magnetic fields, and thus increases the contrast and visibility of various structures within the body during imaging procedures, allowing for more accurate diagnosis.

##What Are The Benefits Of Omnipaque 350?

Omnipaque 350 has several advantages over the traditionally used barium-containing contrast agents. It is significantly less irritating to the respiratory tract and intestinal wall, it is safe and much less likely to cause an adverse reaction or complications, and it is much less expensive than barium-containing agents.

##What Are The Side Effects Of Omnipaque 350?

The most common side effects of Omnipaque 350 include nausea, headache, mild itching, and mild allergic reactions. There is also a risk of more serious side effects such as difficulty breathing, chest pain, chest tightness, skin rash, and hives. These side effects are rare, however, and generally occur in less than 4% of patients.

##Who Should Not Use Omnipaque 350?

Omnipaque 350 should not be administered in patients with known hypersensitivity to the drug or any of its components. Patients with impaired renal function or severe liver dysfunction should also not be given Omnipaque 350.

##What Are The Precautions Before Use Of Omnipaque 350?

Omnipaque 350 should be used with caution in patients with a history of asthma, bronchitis, or other respiratory problems. It should also not be used in pregnant or breastfeeding women unless absolutely necessary.

##How Is Omnipaque 350 Administered?

Omnipaque 350 can be administered intravenously or orally. It is important to drink plenty of fluids after administration to help flush the agent out of the body.

##How Long Does Omnipaque 350 Last In The Body?

The half-life of Omnipaque 350 is approximately 24 hours, meaning it will take 24 hours for half of the drug to be eliminated from the body.

##What Are The Dosage Instructions Of Omnipaque 350?

The dosages of Omnipaque 350 vary depending on the patient's age, body weight, and the procedure being performed. It is important to follow the dosage instructions given by your physician.

##Is Omnipaque 350 Safe For Children?

Omnipaque 350 is generally considered safe for use in children when administered at appropriate dosages. However, it is always best to speak to your pediatrician or healthcare provider before administering Omnipaque 350 to ensure the safety and accuracy of the procedure.

##What Are The Contraindications Of Omnipaque 350?

Omnipaque 350 should not be used in patients with a known hypersensitivity to the drug or any of its components. Patients with impaired renal function or severe liver dysfunction should also not be given Omnipaque 350.

##Are There Any Interactions Between Omnipaque 350 And Other Drugs?

Omnipaque 350 can interact with numerous drugs, including antibiotics, diuretics, and heart and blood pressure medications. It is important to inform your physician about any other drugs you are taking before being administered Omnipaque 350.

##What Should I Do If I Have An Adverse Reaction To Omnipaque 350?

If you experience any adverse reactions to Omnipaque 350, such as difficulty breathing, chest pain, chest tightness, skin rash, or hives, you should immediately contact your healthcare provider.

##What Are The Storage Conditions Of Omnipaque 350?

Omnipaque 350 should be stored at room temperature away from direct sunlight and moisture. It should also be kept out of reach of children and pets.

##What Is The Shelf Life Of Omnipaque 350?

The shelf life of Omnipaque 350 is 3 years from the date of manufacture. It is important to check the expiry date printed on the package before using Omnipaque 350.

##How Is Omnipaque 350 Supplied?

Omnipaque 350 is supplied in various forms, including powder for reconstitution, solutions in vials and prefilled syringes, tablets, and injection devices.

##What Are The Possible Drug Interactions Of Omnipaque 350?

Omnipaque 350 can interact with numerous drugs, including antibiotics, diuretics, and heart and blood pressure medications. It is important to inform your physician about any other drugs you are taking before being administered Omnipaque 350.

##How Often Can Omnipaque 350 Be Administered?

Omnipaque 350 can be administered as often as needed for imaging procedures, depending on the particular procedure and patient’s condition. It is important to follow the instructions of the healthcare provider.

##Can Omnipaque 350 Cause Damage To The Kidneys?

Omnipaque 350 can cause renal damage in certain patients, such as those with pre-existing kidney damage or those with impaired renal function. It is important to discuss any existing kidney conditions with your physician before being administered Omnipaque 350.

##Are There Any Special Precautions And Warnings For Omnipaque 350?

Omnipaque 350 should be used with caution in patients with a history of asthma, bronchitis, or other respiratory problems. It should also not be used in pregnant or breastfeeding women unless absolutely necessary.

##What Are The Common Signs And Symptoms Of Overdose With Omnipaque 350?

The signs and symptoms of an Omnipaque 350 overdose may include severe headaches, nausea and vomiting, chest pain, difficulty breathing, and confusion. If you think you may have overdosed on Omnipaque 350, seek medical attention immediately.

##What Are The Usual Dosages Of Omnipaque 350 For Adults?

The usual dosage for adults is 0.5-1 mmol/kg, given intravenously. The exact dosage depends on patient's weight, body type, and the imaging procedure they are undergoing.

##What Should I Avoid While Taking Omnipaque 350?

You should avoid alcohol while taking Omnipaque 350 as it can increase the risk of adverse effects. You should also avoid consuming large amounts of dairy products for several days after the procedure as they can interfere with the contrast agent's action.

##Does Omnipaque 350 Contain Latex?

Omnipaque 350 does not contain latex. However, it is best to speak to your physician or pharmacist to make sure.

##What Is The Cost Of Omnipaque 350?

The cost of Omnipaque 350 varies depending on the form of the drug. In general, the cost ranges from $20-$200 per dose.

##Can Omnipaque 350 Be Administered Intravenously?

Yes, Omnipaque 350 can be administered intravenously. It is important to follow your physician's instructions carefully when administering Omnipaque 350 intravenously.

##What Are The Advantages Of Omnipaque 350 Over Barium?

Omnipaque 350 has several advantages over the traditionally used barium-containing contrast agents. It is significantly less irritating to the respiratory tract and intestinal wall, it is safe and much less likely to cause an adverse reaction or complications, and it is much less expensive than barium-containing agents.

##Do I Need To Drink Fluids After Taking Omnipaque 350?

Yes, it is important to drink plenty of fluids after taking Omnipaque 350 to help flush the drug out of your body system.

##Can Omnipaque 350 Cause Nausea?

Yes, nausea is one of the most common side effects of Omnipaque 350. However, this is usually mild and does not require medical intervention.

##What Is The Difference Between Omnipaque 350 And Iopamidol?

Omnipaque 350 and Iopamidol are similar contrast agents used in imaging procedures. The main difference between the two is that Omnipaque 350 is slightly more stable and has a longer shelf life.

##What Is The Maximum Dosage Of Omnipaque 350 For Infants?

The maximum dosage of Omnipaque 350 for infants is 0.3 mmol/kg. It is important to follow your physician's instructions carefully when administering Omnipaque 350 to infants and children.

##Can Omnipaque 350 Help Diagnose Kidney Stones?

Yes, Omnipaque 350 is often used to diagnose and monitor kidney stones during imaging procedures such as an X-ray, MRI, or CT scan. Omnipaque 350 helps increase the visibility of the stones, thus aiding in diagnosis.

##What Are The Symptoms Of An Allergic Reaction To Omnipaque 350?

The symptoms of an allergic reaction to Omnipaque 350 may include rash, hives, itching, swelling, breathing difficulty, or chest tightness. If you experience any of these symptoms, contact your doctor immediately.

##Does Omnipaque 350 Need To Be Refrigerated?

No, Omnipaque 350 does not need to be refrigerated. It should be stored at room temperature away from direct sunlight and moisture.

##Can Omnipaque 350 Affect Liver Function?

Yes, Omnipaque 350 can affect liver function. It is important to inform your physician about any pre-existing liver conditions before being administered Omnipaque 350.

##Can Omnipaque 350 Be Used In Pregnant Women?

Omnipaque 350 should only be used in pregnant women if absolutely necessary. It is important to speak to your doctor about any potential risks before being administered Omnipaque 350.

##Is Omnipaque 350 Safe For Patients With Diabetes?

Yes, Omnipaque 350 is generally safe for use in patients with diabetes. It is important to inform your physician about any pre-existing conditions when being administered Omnipaque 350.

##How Can I Prepare For An Omnipaque 350 Procedure?

It is important to hydrate before an Omnipaque 350 procedure. You may also need to fast for several hours before your procedure. It is important to follow your medical care team's instructions.