Olmesan
Olmesan Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Olmesan is a brand name. Its generic name is Olmesartan.
Introduction
Olmesan is an angiotensin receptor blocker that is marketed as Benicar® and Benicar HCT® in the United States. It is a blood pressure medication that works by blocking certain hormones that cause narrowing of the blood vessels leading to reduced blood pressure. Olmesan specifically blocks angiotensin II, helping to reduce sodium and water retention, which decreases blood pressure. It can also help with kidney problems in people with high blood pressure (hypertension). Olmesan is also used to lower the risk of stroke, heart attack, or death in individuals with high blood pressure and a heart-related disease.
Uses for
Olmesan is used to treat hypertension (high blood pressure) in adults and children over 6 years of age. It can also be used to reduce the risk of stroke, heart attack, or death in individuals with high blood pressure and a heart-related disease. It may also be used to improve survival in individuals with left ventricular heart failure after a heart attack.
Mechanism of Action
Olmesan is an angiotensin receptor blocker (ARB) that works by blocking angiotensin II, a hormone that constricts the blood vessels and causes increased blood pressure. In blocking angiotensin II, olmesartan reduces blood vessel constriction and sodium and water retention, ultimately reducing blood pressure. In individuals with high blood pressure and a heart-related disease, olmesartan can help reduce the risk of stroke, heart attack, or death. It can also improve survival in individuals with left ventricular heart failure after a heart attack.
How Long Does it Take to Work?
Olmesan usually begins to lower blood pressure within 1-2 hours of ingestion and its effects can last for 24 hours. To reach maximum effectiveness of this medication, it may take 3-4 weeks. Blood pressure should be monitored regularly.
Absorption
Olmesan is rapidly and almost completely absorbed from the gastrointestinal tract and is completely converted to its active metabolite, olmesartan medoxomil. Peak plasma concentrations of olmesartan occur approximately 1-3 hours after administration.
Route of Elimination
Olmesan is primarily eliminated by the kidneys, with approximately 25% of a dose being excreted unchanged in the urine. The remainder of a dose is metabolized by the liver.
Dosage
The usual recommended dose for treating hypertension in adults is 20 mg once daily. For treating left ventricular heart failure, the usual recommended dose is 40 mg once daily. The dose may be increased to a maximum of 40 mg daily, if needed. For children aged 6-16 years with hypertension, the usual recommended dose is 5 mg once daily, which may be increased to a maximum of 20 mg daily, as needed. For some individuals, it is recommended to divide the daily dose into two smaller doses and take them at different times of the day.
Administration
Olmesan can be taken with or without food. It is best to take olmesartan at the same time each day.
Side Effect
Common side effects of olmesartan include lightheadedness, dizziness, upper respiratory tract infection, stuffy or runny nose, sore throat, stomach pain, diarrhea, constipation, muscle spasm, and joint pain. Some more serious side effects include chest pain, fast and irregular heartbeat, shortness of breath, and swelling of the feet, ankles, and legs.
Toxicity
In animal studies, high doses of olmesartan caused decreased heart rate and decreased sperm motility. There is no reported toxicity from olmesartan in humans.
Precaution
Before taking olmesartan, your doctor should be informed if you have any of the following conditions: if you are pregnant or planning to become pregnant, if you are breastfeeding, if you have kidney or liver problems, if you have a history of dehydration, if you are taking any medications, vitamins, or other supplements, if you have a history of heart or blood vessel disease, or if you have any allergies. Your doctor should also be informed of any medical emergency that you are suspecting and any current or recent illnesses.
Interaction
Olmesan can interact with other medications, vitamins, and herbal supplements. It is important to inform your doctor of any other medications, vitamins, or supplements you are taking. Olmesan should not be taken with other angiotensin receptor blockers, diuretics, lithium, aliskiren, or ACE inhibitors. It should also not be taken with other potassium-sparing diuretics such as spironolactone or amiloride.
Disease Interaction
Olmesan can interact with certain diseases or pre-existing conditions. Your doctor should be informed if you have any of the following conditions: kidney or liver impairment, diabetes, heart failure, thyroid problems, recent heart attack, or recent stroke.
Drug Interaction
Olmesan can interact with certain drugs, vitamins, and herbal supplements. It is important to inform your doctor of any other medications, vitamins, or supplements you are taking. Olmesan should not be taken with other angiotensin receptor blockers, diuretics, lithium, aliskiren, or ACE inhibitors. It should also not be taken with other potassium-sparing diuretics such as spironolactone or amiloride.
Food Interactions
Olmesan may interact with certain foods and beverages. It is especially important to avoid high potassium foods such as avocados, bananas, and oranges, as well as high sodium foods such as processed or canned foods. Alcohol can also interact with olmesartan and should be avoided.
Pregnancy Use
Olmesan should not be used during pregnancy as it may harm a developing baby. It is important to inform your doctor if you are pregnant or planning to become pregnant.
Lactation Use
Olmesan should not be used while breastfeeding as it may pass into breast milk and cause harm to a nursing baby. It is important to inform your doctor if you are breastfeeding or plan to breastfeed.
Acute Overdose
For acute overdose, the signs and symptoms may include low blood pressure, dizziness, lightheadedness, and a slow heart rate. Treatment of an acute overdose may include supportive care, such as oxygen and intravenous fluids, as well as medications to reduce blood pressure and heart rate. It is important to seek medical attention immediately if you suspect an overdose.
Contraindication
Olmesan should not be used if you are allergic to the medication or any of its ingredients. It should also not be used if you are pregnant, breastfeeding, or planning to become pregnant. It should not be used with other angiotensin receptor blockers, diuretics, lithium, aliskiren, or ACE inhibitors.
Use Direction
Take olmesartan exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets. Do not take this medicine in larger or smaller amounts or for longer than recommended. It is important to take olmesartan at the same time each day.
Storage Condition
Store olmesartan at room temperature away from moisture, heat, and light. Keep the bottle tightly closed when not in use.
Volume of Distribution
The volume of distribution of olmesartan is approximately 55 L.
Half-life
The half-life of olmesartan is approximately 13 hours.
Clearance
The total body clearance of olmesartan is approximately 5.3 L/h.
Here you find in details version of Olmesan
Some Frequently Asked Questions About Olmesan
What is Olmesan?
Olmesan is an angiotensin receptor blocker (ARB) medication used to treat high blood pressure and is available in several countries around the world.
Is Olmesan a generic drug?
Yes, Olmesan is available in both brand and generic forms.
How does Olmesan work?
Olmesan is an ARB medication that works by blocking the action of angiotensin II, a chemical that is responsible for narrowing blood vessels. By blocking this action, blood vessels relax and allow for increased blood flow.
What are the side effects of Olmesan?
Common side effects of Olmesan include headache, nausea, fatigue, dizziness, and muscle pain. More serious side effects include low blood pressure, kidney problems, and liver problems.
What is the recommended dosage of Olmesan?
The recommended adult dosage of Olmesan is 20-40 mg per day. Your doctor may adjust your dosage based on your individual needs.
Is Olmesan safe to take while pregnant?
No, Olmesan has not been studied sufficiently in pregnant women. Women who are pregnant or are planning to become pregnant should talk to their doctor before taking Olmesan.
What should I do if I miss a dose of Olmesan?
If you miss a dose of Olmesan, take the missed dose as soon as possible. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule.
How long does it take for Olmesan to start working?
It usually takes about 2 to 4 weeks for Olmesan to reach a steady state in the body and begin to take effect.
What medications should I avoid while taking Olmesan?
You should avoid taking any potassium-sparing diuretics, lithium, certain antifungal medications, or NSAIDs while taking Olmesan. Talk to your doctor before starting any new medications while taking Olmesan.
What should I do if I experience dizziness while taking Olmesan?
If you experience dizziness while taking Olmesan, speak to your doctor about adjusting your dosage or switching to another medication. You should also avoid operating dangerous machinery while taking Olmesan.
Is Olmesan safe for people with diabetes?
Yes, Olmesan is considered safe for people with diabetes. However, your doctor will monitor your blood glucose levels since Olmesan has been known to cause blood sugar fluctuations.
Will Olmesan help to lower cholesterol?
Olmesan can help to lower cholesterol, but it is not usually prescribed for this purpose. Your doctor may prescribe other medications to help to lower your cholesterol.
Does Olmesan have any interaction with alcohol?
Olmesan may increase the effects of alcohol, so it is recommended to avoid drinking while taking this medication.
Can I take Olmesan with other medications?
Yes, Olmesan can be taken with other medications. However, always tell your doctor about all medications (including over-the-counter drugs) and supplements that you are taking.
Is Olmesan safe for elderly patients?
Yes, Olmesan is generally considered safe for elderly patients. Your doctor may adjust your dosage based on your age and other medical conditions.
Does Olmesan cause dehydration?
No, Olmesan does not cause dehydration. However, you may experience some mild dehydration symptoms, such as dry mouth or thirst, while taking this medication. Make sure you drink plenty of fluids throughout the day to stay hydrated.
What is the maximum dosage of Olmesan?
The maximum daily dosage of Olmesan is 40 mg per day. Your doctor may adjust this dosage depending on your individual needs.
Does Olmesan cause weight gain?
No, Olmesan does not usually cause weight gain. However, it is possible to gain weight while taking this medication, so it is important to maintain a healthy diet and exercise regularly.
How long does Olmesan stay in your system?
Olmesan has a half-life of about 24 hours, meaning it takes about 24 hours for the medication to be reduced by half in the body. It can take up to 5 days for Olmesan to be completely cleared from the body.
Can I take Olmesan with ibuprofen?
It is generally not recommended to take Olmesan with ibuprofen. Talk to your doctor before taking any over-the-counter or prescription medications while taking Olmesan.
Is Olmesan a diuretic?
No, Olmesan is not a diuretic. Olmesan is an ARB medication used to treat high blood pressure.
Can Olmesan cause fatigue?
Yes, fatigue is a common side effect of Olmesan. If you experience fatigue while taking Olmesan, speak to your doctor about adjusting your dosage or switching to another medication.
Can I take Olmesan if I have a kidney disorder?
Yes, it is possible to take Olmesan if you have a kidney disorder. However, it is important to speak to your doctor before taking this medication, as it may worsen your condition.
Is Olmesan considered a controlled substance?
No, Olmesan is not a controlled substance. Olmesan is available over the counter in some countries.
Does Olmesan lower blood pressure quickly?
No, Olmesan does not lower blood pressure quickly. It usually takes about 2 to 4 weeks for Olmesan to reach a steady state and begin to take effect.
Is Olmesan considered a safe medication?
Yes, Olmesan is considered a safe medication when taken as directed. Be sure to talk to your doctor about any concerns or questions you may have.
Can I take Olmesan with lisinopril?
No, it is not recommended to take Olmesan with lisinopril. Taking both medications may increase your risk of low blood pressure or kidney problems.
Can Olmesan cause difficulty breathing?
No, Olmesan is not known to cause difficulty breathing. However, if you experience difficulty breathing while taking Olmesan, seek medical attention right away.
Can I take Olmesan on an empty stomach?
Yes, Olmesan can be taken on an empty stomach or with food. However, it is important to take it at the same time each day and with a full glass of water.
Should I take Olmesan with food?
It is not necessary to take Olmesan with food. However, you may find it easier to remember to take your medication if you take it with meals.
Can Olmesan cause diarrhea?
Yes, diarrhea is a common side effect of Olmesan. If you experience diarrhea while taking this medication, talk to your doctor about adjusting your dosage or switching to another medication.
Does Olmesan interact with other medications?
Yes, Olmesan may interact with certain medications, including potassium-sparing diuretics, lithium, certain antifungal medications, and NSAIDs. Talk to your doctor and pharmacist about all medications and supplements you are taking before starting Olmesan.
Can I take Olmesan if I have high cholesterol?
Yes, Olmesan can be taken by patients with high cholesterol. However, your doctor may also prescribe other medications specifically to help lower your cholesterol.