Nevol

Nevol Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Nevol is a brand name. Its generic name is Nebivolol.

Nevol

Nevol is an antihypertensive medicine which belongs to the beta-blocking class of drugs. It is mainly used to treat hypertension (high blood pressure). It works by blocking a hormone in the body called noradrenaline (norepinephrine), thus reducing heart rate and the force of heart muscle contraction, resulting in a decrease in heart pressure.

Uses for

Nevol is primarily indicated to treat mild to moderate high blood pressure (hypertension). It may also be indicated for the following conditions:

• Angina (chest pain)
• Congestive heart failure
• Atrial fibrillation
• Coronary artery disease

Mechanism of Action

Nevol works by blocking the action of the hormone noradrenaline (norepinephrine). By blocking the action of noradrenaline onBeta-1 receptors in the heart, Nevol reduces the force of muscle contraction in the heart and also reduces the heart rate. This results in the reduction of heart pressure and gives relief from hypertension.

How Long Does It Take to Work?

Nevol works quickly and the effects can be seen within an hour of taking the medicine. However, it usually takes about 4 weeks for the full effects to be seen. This is generally the time frame necessary for the medicine to reach the therapeutic levels in the body.

Absorption

Nevol is readily absorbed from the gastrointestinal tract. The peak plasma concentration is usually reached within 1-2 hours after an oral dose.

Route of Elimination

Nevol is mainly eliminated through the urine and/or feces. Around 15-20% of the administered dose is excreted through the urine as unchanged drug.

Dosage

The recommended dosage for treating hypertension is 5-20 mg taken once daily. The dosage may be increased gradually as per the doctor’s instructions. It is important to take the dose regularly and at the same time each day for the best effect.

Administration

Nevol should be taken orally with or without food. The tablet should not be chewed or crushed as this may reduce the effectiveness. It is also important to follow the doctor’s instructions and advice as different people may need different doses to get the desired effect.

Side Effect

Nevol may cause side effects in some people. The most common side effects are fatigue, headaches, dizziness, and dry mouth. Less common side effects include nausea, vomiting, diarrhoea, and skin rashes. If these side effects persist or worsen, contact your doctor.

Toxicity

Nevol is generally safe and well tolerated. However, overdosage may cause symptoms such as hypotension (low blood pressure), bradycardia (slow heart rate), and coma. In the event of an overdose, seek medical attention immediately.

Precautions

• Nevol should be used with caution in elderly patients, as it may increase the risk of falls and fractures.
• The use of Nevol in pregnant women is not recommended as it may cause fetal harm.
• Nevol should be used with caution in patients with asthma or other breathing problems, since it may cause difficulty breathing.
• People with kidney or liver disease should consult their doctor before using Nevol.

Interaction

Nevol may interact with other medicines, herbs, vitamins, minerals, or dietary supplements, so it is important to inform your doctor about any medicines you may be taking. Also, certain drugs may interfere with how Nevol works, so contact your doctor if you are taking any of the following:

• MAO inhibitors (e.g. isocarboxazid, phenelzine, tranylcypromine, etc.)
• Beta-blockers (e.g. propranolol, atenolol, metoprolol, etc.)
• Angiotensin-converting enzyme (ACE) inhibitors (e.g. benazepril, enalapril, lisinopril, etc.)
• Calcium channel blockers (e.g. diltiazem, verapamil, etc.)
• Tricyclic antidepressants (e.g. amitriptyline, nortriptyline, etc.)

Disease Interaction

Nevol may interact with certain diseases, so it is important to inform your doctor about any conditions you have. People with asthma, heart block, bradycardia, heart failure, or certain other diseases should use this medicine cautiously and with close monitoring.

Drug Interaction

Nevol may interact with certain drugs, so it is important to inform your doctor about any medications you may be taking. Also, some drugs may interfere with the way Nevol works, so contact your doctor if you are taking any of the following: Tricyclic antidepressants, antipsychotic drugs, anti-seizure drugs, anti-anxiety medicines, beta-blockers, and calcium channel blockers.

Food Interactions

Nevol is not known to interact with food. However, it is best to take Nevol at the same time each day, preferably after food.

Pregnancy Use

Nevol should not be used in pregnant women, as it may cause harm to the fetus. It is best to consult your doctor before taking this medicine during pregnancy.

Lactation Use

Nevol should not be used while breastfeeding, as it may pass into the breast milk and affect the baby. It is best to consult your doctor before taking this medicine while breastfeeding.

Acute Overdose

In cases of an acute overdose, symptomatic treatment should be given and medical attention should be sought immediately. Symptoms of an overdose may include hypotension (low blood pressure), bradycardia (slow heart rate), and coma.

Contraindication

Nevol should not be used in people with allergy or hypersensitivity to the active ingredient, or with certain conditions such as asthma, heart block, bradycardia, heart failure, or uncontrolled severe hypertension.

Use Directions

Nevol should be taken orally as prescribed. The usual starting dose is 5-20 mg taken once daily, usually at the same time each day. The dosage may be adjusted as per your doctor’s instructions. It is important to take the dose regularly and at the same time each day for the best effect.

Storage Conditions

Nevol should be stored at room temperature and protected from light and moisture. It should also be kept out of the reach of children and pets.

Volume of Distribution

Nevol has an estimated volume of distribution of about 3.6L/Kg.

Half Life

The elimination half-life of Nevol is about 10 hours.

Clearance

Nevol has an estimated clearance rate of about 5.3L/hr/Kg.

Here you find in details version of Nevol

Some Frequently Asked Questions About Nevol

What is Nevol?

Nevol is a selective beta-1 receptor blocker and vasodilator drug used to treat high blood pressure and left ventricular dysfunction.

What is Nevol used for?

Nevol is used to treat high blood pressure and left ventricular dysfunction. It is also used off label to treat chest pain and migraine prevention.

What is the mechanism of action of Nevol?

Nevol works by blocking beta-1 adrenergic receptors in the heart, which decreases heart rate, reduces the amount of blood pumped from the heart, and lowers the force of contraction of the heart muscle. It also constricts blood vessels, which reduces blood pressure.

How long does Nevol take to work?

Nevol can start working as soon as 30 minutes after it is taken, however, the full effects may not be seen for several weeks.

Is Nevol a controlled substance?

No, Nevol is not a controlled substance.

Is Nevol safe?

Yes, Nevol is generally safe when taken as prescribed. However, like all medications, Nevol may cause side effects in some patients.

What are the side effects of Nevol?

Common side effects of Nevol include headache, fatigue, dizziness, low blood pressure, and nausea. More serious side effects of Nevol may include shortness of breath, chest pain, irregular heartbeat, and swelling of the ankles or feet.

Can I take Nevol while pregnant?

If you are pregnant or planning to become pregnant, you should consult with your doctor before taking Nevol. It is not known if Nevol is safe for use during pregnancy.

Can I take Nevol while breastfeeding?

You should consult with your doctor before taking Nevol while breastfeeding. It is not known if Nevol is safe for use while breastfeeding.

Does Nevol interact with any other medications?

Yes, Nevol may interact with other medications, including blood pressure medications, cholesterol medications, and certain antibiotics. You should always tell your healthcare provider about all other medications you are taking before starting Nevol.

Can I split Nevol tablets?

It is best to consult with your doctor or pharmacist before splitting Nevol tablets, as some tablets may be too small or fragile to accurately split.

When should I take Nevol?

Nevol is usually taken once daily, in the morning. It is important to take it at the same time each day and to follow all instructions on how to take Nevol.

What should I do if I miss a dose of Nevol?

If you miss a dose of Nevol, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.

What should I do if I overdose on Nevol?

If you think you may have overdosed on Nevol, contact your local poison control center or emergency room right away.

What are the storage requirements for Nevol?

Nevol tablets should be stored at room temperature, away from heat and moisture. Keep out of reach of children.

How long does Nevol stay in my system?

Nevol is usually cleared from the system within 24 hours, however, it may take longer in some individuals.

Can I drink alcohol while taking Nevol?

It is not recommended to drink alcohol while taking Nevol, as it can increase the risk of side effects.

Will Nevol lower my blood pressure too much?

Nevol is generally effective at lowering blood pressure. However, it is important to follow your doctor's instructions closely, as too much of a decrease in blood pressure can cause serious side effects.

Can I take Nevol with other blood pressure medications?

Yes, your doctor may prescribe Nevol in combination with other blood pressure medications. It is important to take all medications as prescribed and to inform your doctor of any side effects.

What are the differences between Nevol and other beta blockers?

Nevol is a selective beta-1 receptor blocker, meaning it blocks beta-1 receptors in the heart, while having less of an effect on other areas of the body. Other beta blockers may be non-selective, meaning they can block beta-1 and beta-2 receptors in the body.

Is Nevol effective for reducing the risk of heart disease?

Nevol may reduce the risk of death and heart attack in people with heart failure, particularly when taken in combination with other medications. Nevol is also used to reduce the risk of stroke and sudden death in people who have already had a heart attack.

Can I exercise while taking Nevol?

Yes, you can exercise while taking Nevol. However, you should discuss any regular exercise program with your doctor before starting it. Be sure to drink plenty of water while exercising and take breaks if needed.

What are the long-term effects of taking Nevol?

Nevol is generally well tolerated and the long-term effects are positive. Nevol has been found to reduce the risk of stroke, heart attack, and sudden death in people with heart failure.

Does Nevol cause weight gain?

Weight gain is not a common side effect of Nevol. However, some people do report gaining a small amount of weight while taking Nevol.

Can I take Nevol if I have asthma or COPD?

Nevol is not recommended for people with asthma or COPD. It is important to tell your doctor about all medical conditions before taking Nevol.

Is Nevol available as a generic drug?

Yes, Nevol is available as a generic drug.

What is the cost of Nevol?

The cost of Nevol depends on the dosage, the form, and the pharmacy. A generic version of Nevol is typically cheaper than the brand-name version.

Does Nevol cause frequent urination?

No, Nevol does not typically cause frequent urination. However, some people may experience side effects such as frequent urination or increased thirst while taking Nevol.

Does Nevol have anticoagulant properties?

No, Nevol does not have anticoagulant properties. People taking blood thinning medications such as warfarin should not take Nevol.

Can I take an antihistamine with Nevol?

Yes, most antihistamines are safe to take with Nevol. Be sure to tell your doctor about all medications, supplements, and vitamins you are taking before starting Nevol.

Can I take Nevol if I have diabetes?

Yes, Nevol is generally safe for people with diabetes. However, it is important to tell your doctor about any history of diabetes before taking Nevol.

What are the signs of an allergic reaction to Nevol?

Signs of an allergic reaction to Nevol may include difficulty breathing, rash, hives, swelling of the face or tongue, itching, or tightness in the chest. If you experience any of these symptoms, contact your healthcare provider immediately.

Can I take Nevol with vitamins or supplements?

Yes, but it is important to tell your doctor about any vitamins or supplements you are taking before starting Nevol. Some vitamins or supplements may interact with Nevol.

Can I take over-the-counter medications with Nevol?

Yes, it is generally safe to take over-the-counter medications with Nevol. However, it is important to tell your doctor about any over-the-counter medications you are taking before starting Nevol.

What is the difference between Nevol and other beta-blockers?

Nevol is a selective beta-1 receptor blocker, meaning it blocks beta-1 receptors in the heart, while having less of an effect on other areas of the body. Other beta-blockers may be non-selective, meaning they can block beta-1 and beta-2 receptors in the body.

What should I do if I experience side effects while taking Nevol?

If you experience side effects while taking Nevol, contact your doctor or healthcare provider right away. They may be able to adjust your dose or suggest other treatments to help alleviate the side effects.

Can I stop taking Nevol without consulting my doctor?

No, it is important to always talk to your doctor before stopping or changing your dose of Nevol. If you suddenly stop or reduce your Nevol dose, it may cause serious heart problems or even death.

Can elderly patients take Nevol?

Yes, Nevol is generally safe for elderly patients when taken as directed. However, your doctor may adjust your dose to account for any age-related physical changes. Be sure to visit your doctor regularly while taking Nevol.

Does Nevol cause dry eyes?

No, dry eyes is not a common side effect of Nevol. If you experience dry eyes while taking Nevol, contact your doctor.

Q Does Nevol interact with grapefruit or grapefruit juice?

Yes, Nevol may interact with grapefruit or grapefruit juice. It is important to discuss any dietary changes with your doctor before taking Nevol.