Mylan-Bupropion XL
Mylan-Bupropion XL Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Mylan-Bupropion XL is a brand name. Its generic name is Bupropion.
Introduction and Uses
Mylan-Bupropion XL, sold under the brand name Wellbutrin, is used as an atypical antidepressant. It is also used to treat depression, seasonal affective disorder, and attention deficit hyperactivity disorder. Mylan-Bupropion XL can also be used as an augmentation therapy in cases of partial response to other agents.
Mechanism of Action
Mylan-Bupropion XL is a hydroxybupropion, containing a chlorinated phenylthiophene ring. It is thought to increase norepinephrine and dopamine in the brain, which are neurotransmitters associated with mood regulation and happiness. This modulation of the brain’s neurotransmitter levels may have a positive effect on the mood of individuals with depression.
How long does it take to work?
Mylan-Bupropion XL typically takes two to four weeks to begin its therapeutic effects. However, certain individuals may experience an alleviation of symptoms earlier or later than this window.
Absorption, Route of Elimination and Dosage
Mylan-Bupropion XL is available in immediate-release (IR), controlled-release (CR) or extended-release (XR) formulations. On the IR form, it is recommended to initially take 75mg twice daily for six to eight days, increasing to 150mg twice daily thereafter. On the CR or XR form, it is recommended to initially take 150mg once daily for four days, increasing to 300mg once daily thereafter. Mylan-Bupropion XL has a bioavailability of 55-77%, and is typically dosed with food or milk to decrease gastrointestinal upset. Mylan-Bupropion XL is typically eliminated by the kidney.
Administration, Side Effects, Toxicity, Precautions and Interactions
Mylan-Bupropion XL should be taken orally with water. Common side effects of bupropion include agitation, dry mouth, insomnia, headache, nausea, constipation, tremor, hallucinations and dizziness. Serious side effects can include seizures, suicidal thoughts or changes in behavior relating to depression. Overdose of bupropion can lead to life-threatening toxicity, and cases should be referred for immediate medical attention. Mylan-Bupropion XL can cause drug interactions with various medications, and conversely can interact with certain drugs to reduce the efficacy of bupropion. While some food interactions have been observed, bupropion does not typically alter the absorption or effectiveness of foods.
Disease Interactions, Drug Interactions, Pregnancy Use, Lactation Use, Acute Overdose, Contraindication, Use Direction, Storage Conditions, Volume of Distribution, Half-Life, and Clearance
Mylan-Bupropion XL may interact with other drugs, and caution should be exercised when taking bupropion with certain medications, such as antipsychotics, MAO inhibitors, or anticonvulsants. Mylan-Bupropion XL should be avoided during the first trimester of pregnancy, and otherwise should only be used if the potential benefits outweigh the potential risks. Mylan-Bupropion XL is excreted in breast milk, and caution should be taken if used while breastfeeding. In case of acute overdose, the patient should be referred for medical attention. Contraindications for bupropion include seizures, glaucoma, or a hypersensitivity or adverse reaction to this drug. Mylan-Bupropion XL is supplied as tablets and should be taken orally with water as prescribed by the prescribing physician. Mylan-Bupropion XL should be stored at controlled room temperature away from light and moisture and kept in the tight, original container when not in use. The volume of distribution of bupropion is 0.72-1.7 L/kg, and it has a terminal half-life of 8-24 hours. Its clearance from the body is 1.1 L/h/kg.
Here you find in details version of Mylan-Bupropion XL
Some Frequently Asked Questions About Mylan-Bupropion XL
What is Mylan-Bupropion XL?
Mylan-Bupropion XL is an antidepressant medication that is used to treat major depressive disorder, seasonal affective disorder, and to help people quit smoking.
How does Mylan-Bupropion XL work?
Mylan-Bupropion XL works as an antidepressant by increasing the levels of certain chemicals in the brain known as neurotransmitters. These chemicals help to balance mood and improve the symptoms of depression.
What are the side effects of Mylan-Bupropion XL?
Common side effects of bupropion include dry mouth, headaches, dizziness, nausea, constipation, anxiety, and insomnia. Other serious side effects include allergic reactions, changes in vision, seizures, and an increased risk of suicide or thoughts of suicide.
How long does it take for Mylan-Bupropion XL to work?
It can take several weeks for Mylan-Bupropion XL to begin to take effect. However, some people may experience relief of symptoms within the first week of taking the medication.
What is the dosage of Mylan-Bupropion XL?
The usual recommended dose of Mylan-Bupropion XL is 100 to 150 mg per day, divided into two or three doses. Your doctor may prescribe different doses if necessary for your particular condition.
Can I take Mylan-Bupropion XL with other medications?
Yes, you can take Mylan-Bupropion XL with other medications, however it is important to speak to your doctor or pharmacist before taking any additional medications, especially if you are already taking other antidepressant medications.
What forms does Mylan-Bupropion XL come in?
Mylan-Bupropion XL is available in different forms, including tablets, sustained-release tablets, and extended-release tablets. It is also available as an oral suspension.
How should I take Mylan-Bupropion XL?
Mylan-Bupropion XL should be taken as prescribed by your doctor. Always follow the instructions on the label and speak to your doctor or pharmacist if you have any questions.
Can I overdose on Mylan-Bupropion XL?
Yes, it is possible to overdose on bupropion. Symptoms of an overdose may include nausea, vomiting, confusion, tremor, convulsions, and breathing difficulties. If you think you have taken too much of this medication, seek immediate medical attention.
Can Mylan-Bupropion XL cause weight gain?
Weight gain can be a side effect of Mylan-Bupropion XL, however not everyone experiences this side effect. It is important to speak to your doctor if you are experiencing significant weight gain while taking this medication.
Is Mylan-Bupropion XL safe to use during pregnancy?
Mylan-Bupropion XL should not be used during pregnancy, unless specifically directed by your doctor or healthcare provider. It is not recommended for women who are nursing, due to the potential for serious side effects in a nursing baby.
Can Mylan-Bupropion XL help me quit smoking?
Mylan-Bupropion XL may be prescribed to help people quit smoking. This medication works by reducing the physical and psychological craving for nicotine. Your doctor can help you create a personalized smoking cessation plan and determine the best dose of bupropion for you.
When should I take Mylan-Bupropion XL?
Mylan-Bupropion XL should be taken as directed by your doctor. Usually, it is taken twice a day, although extended-release tablets can also be taken once a day. It is important to take this medication at the same time each day for optimal effectiveness.
Does Mylan-Bupropion XL cause insomnia?
Insomnia is a common side effect of Mylan-Bupropion XL. If you are experiencing insomnia while taking this medication, you should talk to your doctor. They may be able to adjust your dose or prescribe a different medication.
How do I store Mylan-Bupropion XL?
Mylan-Bupropion XL should be stored at room temperature in a dry, dark place. It should not be kept in the bathroom, as this is an unsuitable environment and could adversely affect the medication. Keep the medication out of reach of children and always dispose of unused medication in a safe, secure manner.
Is Mylan-Bupropion XL a controlled substance?
No, Mylan-Bupropion XL is not a controlled substance. It is a non-narcotic medication.
Can I drink alcohol while taking Mylan-Bupropion XL?
No, it is not recommended to drink alcohol while taking Mylan-Bupropion XL, as this may increase the risk of side effects. If you must drink alcohol, speak to your doctor about how to do so safely while taking Mylan-Bupropion XL.
What should I do if I miss a dose of Mylan-Bupropion XL?
If you miss a dose of Mylan-Bupropion XL, take it as soon as possible. However, if it is close to time for your next dose, skip the missed dose and take your next one at the usual time. Do not take a double dose to make up for the missed one.
Does Mylan-Bupropion XL work for everyone?
No, Mylan-Bupropion XL may not work for everyone. It is important to follow the instructions of your doctor and discuss any concerns that you may have. There are other antidepressant medications available, so you and your doctor may decide to switch medications if Mylan-Bupropion XL does not seem to be effective.
Can Mylan-Bupropion XL cause depression?
No, Mylan-Bupropion XL is not known to cause depression. It is used to treat depression by increasing certain chemicals in the brain. However, if you are already taking this medication and notice an increase in depressive symptoms, speak to your doctor immediately.
Can I take Mylan-Bupropion XL while breastfeeding?
No, Mylan-Bupropion XL is not recommended for women who are breastfeeding, as it can cause serious side effects in nursing babies. Speak to your doctor for more information.
When should I talk to my doctor about Mylan-Bupropion XL?
It is important to talk to your doctor if you are experiencing any serious side effects or if the medication does not seem to be helping with your symptoms. Your doctor may adjust your dose or suggest another medication.
Can I take Mylan-Bupropion XL if I have diabetes?
It is generally safe to take Mylan-Bupropion XL if you have diabetes, however it is important to consult with your doctor first. Mylan-Bupropion XL can sometimes affect blood sugar levels, so your doctor may adjust your dose of insulin, metformin, or other diabetes medication.
What should I do if I experience an allergic reaction to Mylan-Bupropion XL?
Stop taking the medication immediately and seek medical attention if you experience an allergic reaction, which may include difficulty breathing, swelling of the face, lips, tongue, or throat, or rash. It is important to tell your doctor right away if you experience any of these symptoms.
Can I take Mylan-Bupropion XL if I have liver disease?
No, it is not recommended to take Mylan-Bupropion XL if you have liver disease. Speak to your doctor for more information.
Is Mylan-Bupropion XL a sedative?
No, Mylan-Bupropion XL is not a sedative. It is an antidepressant medication that works by increasing certain chemicals in the brain.
Can I take Mylan-Bupropion XL if I have anxiety?
Yes, Mylan-Bupropion XL may be prescribed to treat anxiety, as well as depression. Your doctor may adjust your dose in order to optimize the effectiveness of the medication for your particular condition.
Can Mylan-Bupropion XL cause hair loss?
Yes, hair loss is a possible side effect of Mylan-Bupropion XL, although it is not common. Speak to your doctor is you are experiencing this side effect.
Can I take Mylan-Bupropion XL if I have high blood pressure?
Yes, Mylan-Bupropion XL can be taken to treat depression or anxiety if you have high blood pressure. However, it is important to tell your doctor so that they can monitor your blood pressure levels closely and adjust your dose of medication if necessary.
Can Mylan-Bupropion XL cause headaches?
Yes, headaches are a common side effect of Mylan-Bupropion XL. If you experience persistent or severe headaches while taking this medication, speak to your doctor.
Can I take other medications while taking Mylan-Bupropion XL?
Yes, you can take other medications while taking Mylan-Bupropion XL. However, it is important to tell your doctor about any medications that you are currently taking to make sure there are no interactions between them.
Can Mylan-Bupropion XL cause insomnia?
Yes, insomnia is a possible side effect of Mylan-Bupropion XL. Speak to your doctor if you are experiencing difficulty sleeping while taking this medication.
Does Mylan-Bupropion XL have any long-term side effects?
Long-term side effects of Mylan-Bupropion XL can include dry mouth, vision changes, and weight gain. Speak to your doctor if you are concerned about any long-term side effects of this medication.
Is Mylan-Bupropion XL addictive?
No, Mylan-Bupropion XL is not considered to be addictive. However, it is important to take this medication as prescribed by your doctor and not to drink alcohol while taking it.
Can Mylan-Bupropion XL cause weight loss?
Some people may experience weight loss while taking Mylan-Bupropion XL, however this is not common. Speak to your doctor if you are concerned about gaining or losing too much weight while taking this medication.
Can I take Mylan-Bupropion XL if I have kidney disease?
Yes, it is generally safe to take Mylan-Bupropion XL if you have kidney disease, however it is important to tell your doctor so that they can adjust your dose as necessary. Your doctor may also want to monitor your kidney function while you are taking Mylan-Bupropion XL.
Does Mylan-Bupropion XL cause anxiety?
No, Mylan-Bupropion XL is not known to cause anxiety, however anxiety may be a side effect of this medication. Speak to your doctor about any anxiety that you experience while taking this medication.
Can I open the Mylan-Bupropion XL tablets and sprinkle them on food?
No, it is not recommended to open the Mylan-Bupropion XL tablets and sprinkle them on food. This medication should be taken whole with plenty of fluids to prevent choking and potential side effects.