Mycophenolic Acid Morpholinoethyl Ester
Mycophenolic Acid Morpholinoethyl Ester Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Mycophenolic Acid Morpholinoethyl Ester is a brand name. Its generic name is Mycophenolate Mofetil.
Introduction
Mycophenolic Acid Morpholinoethyl Ester (MMF) is a medication used to treat certain immune-mediated conditions such as systemic lupus erythematosus or inflammatory bowel disease. It is also used to help prevent the rejection of organ transplant. It is an ester prodrug of mycophenolic acid, which works by suppressing or reducing the body's immune system.Uses
Mycophenolate mofetil is used to prevent rejection of organ transplants, such as kidney, heart, and liver, as well as to treat inflammatory bowel disease and lupus erythematosus.Mechanism of Action
Mycophenolic Acid Morpholinoethyl Ester works by blocking certain steps in the production of certain cells in the immune system. It prevents the activation and proliferation of certain lymphocytes that contribute to an immune response, leading to decreased inflammation in the body. It has also been found to reduce the rates of organ rejection in organ transplant patients.How long does it take to work?
The effects of mycophenolate mofetil can be quite variable, depending upon the underlying condition and the patient. In general, the medication may take anywhere from several days to several weeks to achieve its full effect.Absorption
Mycophenolate mofetil is rapidly and almost completely absorbed from the gastrointestinal tract with an absolute bioavailability of 80-90%. Peak serum concentrations are generally reached within 2-4 hours after administration.Route of Elimination
Mycophenolic Acid Morpholinoethyl Ester is mainly metabolised and eliminated through the kidneys in the form of mycophenolic acid.Dosage
The recommended dose of Mycophenolic Acid Morpholinoethyl Ester is based on weight and medical condition. Generally, it should be taken 2-3 times a day either in the form of a tablet or capsule (1g or 500mg). It should be taken with food and should not be chew, split, or crushed.Administration
Mycophenolate mofetil is generally taken orally with a meal or snack. It can also be taken in combination with other immunosuppressants, usually in the form of tacrolimus or cyclosporine.Side Effects
Common side effects of mycophenolate mofetil include: nausea, vomiting, diarrhea, abdominal pain, hair loss, fatigue, and headache. Other less common side effects include: dizziness, rashes or itching, depression, difficulty breathing, fever, and chest pain.Toxicity
The most common toxicities associated with mycophenolate mofetil are gastrointestinal disturbances. Mycophenolate mofetil is not known to have any serious long-term toxicities, however it is only recommended to be taken under the close supervision of a medical professional.Precautions
Mycophenolate mofetil should not be taken if you are pregnant, planning to become pregnant, breastfeeding, or are allergic to any of the ingredients in the medication. It is also important to tell your doctor if you have any liver, kidney or heart disease.Interaction
Mycophenolate mofetil is known to interact with many other medications, including certain antibiotics, antifungals, cholesterol-lowering medications, barbiturates, and hormones. Taking any of these medications could affect the efficacy of Mycophenolic Acid Morpholinoethyl Ester or increase the risk of side effects.Disease Interaction
Mycophenolate mofetil can reduce the effectiveness of certain vaccines, such as the measles, mumps, and rubella (MMR) vaccine. It can also worsen conditions such as lupus, diabetes, and certain types of cancer such as lymphoma.Drug Interaction
Mycophenolate mofetil can interact with many other medications. This includes certain antibiotics, antifungals, cholesterol-lowering medications, hormones, and barbiturates. Be sure to tell your doctor if you take any of these medications before taking mycophenolate mofetil.Food Interaction
Mycophenolate mofetil is best taken with food, as grape fruit juice or certain foods with high concentrations of calcium, iron, dietary fiber, and vitamin D can possibly reduce the medication's absorption. Additionally, it is recommended to avoid alcohol while taking Mycophenolic Acid Morpholinoethyl Ester due to increased risk of side effects.Pregnancy Use
Mycophenolate mofetil is generally not recommended for pregnant women due to possible serious side effects.Lactation Use
Mycophenolate mofetil is not recommended for breastfeeding mothers due to the potential risk of passing the drug to their infants.Acute Overdose
High doses of Mycophenolate mofetil can lead to an increased risk of serious side effects. In case of an overdose, seek medical attention immediately and inform your doctor or pharmacist of the last dose taken.Contraindication
Mycophenolate mofetil is contraindicated in pregnant women as well as those with a known allergy to the medication. It is also contraindicated in patients with certain active infections or conditions that suppress the immune system.Use Direction
Take Mycophenolate mofetil exactly as prescribed by your doctor. Do not take more or less of it or take it for longer than recommended. Take it with food and follow all instructions on the prescription label.Storage Condition
Mycophenolate mofetil should be stored at room temperature between 59°F and 77°F (15°C and 25°C). It should be kept out of reach of children, and away from light and heat.Volume of Distribution
Mycophenolate mofetil has relatively large volume of distribution (9L-20L).Half Life
The half-life of Mycophenolate is 2-3 hours.Clearance
Mycophenolate mofetil is cleared primarily by the kidneys, with a reported renal clearance of 37-144 mL/min.Here you find in details version of Mycophenolic Acid Morpholinoethyl Ester
Some Frequently Asked Questions About Mycophenolic Acid Morpholinoethyl Ester
.What is Mycophenolic Acid Morpholinoethyl Ester?
Mycophenolic Acid Morpholinoethyl Ester is an immunosuppressive medication used to prevent the rejection of organ transplants by suppressing the body’s immune system. It works by preventing the growth of white blood cells, which are a part of the body’s immune response.
What are the side effects of Mycophenolic Acid Morpholinoethyl Ester?
The most common side effects of Mycophenolic Acid Morpholinoethyl Ester are nausea, abdominal pain, vomiting, diarrhea, and headaches. Other rarer side effects can include hair loss, changes in blood counts, high cholesterol, weight gain, and liver problems.
What is the recommended dosage of Mycophenolic Acid Morpholinoethyl Ester?
The recommended dosage of Mycophenolic Acid Morpholinoethyl Ester varies depending on the individual, the type of transplant, and other factors. Your doctor will be able to advise you on the best course of action.
What is Mycophenolic Acid Morpholinoethyl Ester used for?
Mycophenolic Acid Morpholinoethyl Ester is primarily used to prevent organ rejection in people who have undergone transplants, such as kidney transplants or heart transplants.
What is the difference between Mycophenolic Acid Morpholinoethyl Ester and Mycophenolic Acid?
Mycophenolic Acid Morpholinoethyl Ester is the active ingredient in Mycophenolic Acid. Mycophenolic Acid Morpholinoethyl Ester is converted into its active form, Mycophenolic Acid, by enzymes in the body. Mycophenolic Acid Morpholinoethyl Ester is more stable than Mycophenolic Acid and has a longer shelf-life.
Is Mycophenolic Acid Morpholinoethyl Ester a chemotherapy drug?
No, Mycophenolic Acid Morpholinoethyl Ester is not a chemotherapy drug. It is an immunosuppressant drug and does not kill cancer cells directly.
What is the difference between Mycophenolic Acid Morpholinoethyl Ester and Cyclosporine?
Mycophenolic Acid Morpholinoethyl Ester and Cyclosporine are both immunosuppressant drugs used to prevent the rejection of transplanted organs. While Cyclosporine can be taken orally, Mycophenolic Acid Morpholinoethyl Ester must be taken intravenously or as a capsule. Mycophenolic Acid Morpholinoethyl Ester is generally safer to use than Cyclosporine.
How often should I take Mycophenolic Acid Morpholinoethyl Ester?
Your dosage and frequency of use should be determined by your doctor. Generally, Mycophenolic Acid Morpholinoethyl Ester is taken twice a day, with meals.
What should I do if I miss a dose of Mycophenolic Acid Morpholinoethyl Ester?
If you miss a dose of Mycophenolic Acid Morpholinoethyl Ester, take it as soon as you remember. If it is close to the time for your next dose, skip the missed dose and take your next dose when due.
What should I avoid while taking Mycophenolic Acid Morpholinoethyl Ester?
You should avoid taking any other medications while taking Mycophenolic Acid Morpholinoethyl Ester, unless your doctor has approved it. You should also try to avoid alcohol and smoking while taking Mycophenolic Acid Morpholinoethyl Ester.
Does Mycophenolic Acid Morpholinoethyl Ester interact with any other medications?
Yes, Mycophenolic Acid Morpholinoethyl Ester can interact with other medications, so you should always tell your doctor about any other medications you are taking, including vitamins, herbal supplements, and non-prescription medications.
Does Mycophenolic Acid Morpholinoethyl Ester cause weight gain?
Weight gain is a rare side effect of Mycophenolic Acid Morpholinoethyl Ester. If you experience this, it is important to talk to your doctor about it.
Can I take Mycophenolic Acid Morpholinoethyl Ester while pregnant?
No, Mycophenolic Acid Morpholinoethyl Ester is not recommended for use during pregnancy, as it can cause serious harm to an unborn baby.
Can I take Mycophenolic Acid Morpholinoethyl Ester while breastfeeding?
No, it is not recommended to take Mycophenolic Acid Morpholinoethyl Ester while breastfeeding, as it can pass into breastmilk and could harm a nursing baby.
Can I take Mycophenolic Acid Morpholinoethyl Ester with other immunosuppressant drugs?
Yes, Mycophenolic Acid Morpholinoethyl Ester can be taken with other immunosuppressant drugs, such as Cyclosporine, Tacrolimus, and Sirolimus. However, it is important to talk to your doctor before taking any other medications while taking Mycophenolic Acid Morpholinoethyl Ester.
What are the symptoms of an allergic reaction to Mycophenolic Acid Morpholinoethyl Ester?
The symptoms of an allergic reaction to Mycophenolic Acid Morpholinoethyl Ester can include hives, rash, chest tightness, difficulty breathing, and swelling of the face, lips, tongue, or throat. If you experience any of these symptoms, it is important to seek medical help right away.
What should I do if I experience stomach pain or nausea while taking Mycophenolic Acid Morpholinoethyl Ester?
If you experience stomach pain or nausea while taking Mycophenolic Acid Morpholinoethyl Ester, it is important to talk to your doctor. They may recommend additional treatments to help reduce these symptoms.
Does Mycophenolic Acid Morpholinoethyl Ester cause hair loss?
Hair loss is a rare side effect of Mycophenolic Acid Morpholinoethyl Ester. If you experience this, it is important to talk to your doctor about it.
Can I take other medications while taking Mycophenolic Acid Morpholinoethyl Ester?
Yes, you can take some other medications while taking Mycophenolic Acid Morpholinoethyl Ester, however it is important to talk to your doctor before taking any other medications, including vitamins, over-the-counter medications, and herbal supplements.
Can Mycophenolic Acid Morpholinoethyl Ester cause fertility problems?
Yes, Mycophenolic Acid Morpholinoethyl Ester can cause fertility problems in men and women. If you are planning on getting pregnant, it is important to talk to your doctor about this.
What should I do if I experience blurred vision while taking Mycophenolic Acid Morpholinoethyl Ester?
If you experience blurred vision while taking Mycophenolic Acid Morpholinoethyl Ester, it is important to talk to your doctor. They may need to adjust your dosage or change your medication.
Will I need to have blood tests while taking Mycophenolic Acid Morpholinoethyl Ester?
Yes, you may need to have periodic blood tests to monitor the effectiveness of Mycophenolic Acid Morpholinoethyl Ester. Your doctor will be able to advise you on how often these tests should be done.
Does Mycophenolic Acid Morpholinoethyl Ester increase the risk of infection?
Yes, Mycophenolic Acid Morpholinoethyl Ester can increase the risk of infection, as it suppresses the body’s immune system. It is important to talk to your doctor about any symptoms of infection, such as fever or chills.
Does Mycophenolic Acid Morpholinoethyl Ester cause bone marrow depression?
Yes, Mycophenolic Acid Morpholinoethyl Ester can cause bone marrow depression, which can lead to a decrease in the production of red and white blood cells. If you experience any symptoms of bone marrow depression, such as fatigue or difficulty fighting off infections, it is important to talk to your doctor.
Can I stop taking Mycophenolic Acid Morpholinoethyl Ester without talking to my doctor?
No, it is important to talk to your doctor before stopping any medication. Stopping Mycophenolic Acid Morpholinoethyl Ester suddenly can increase the risk of rejection of the transplanted organ. Your doctor will be able to advise you on the best course of action.
Does Mycophenolic Acid Morpholinoethyl Ester cause liver damage?
Yes, Mycophenolic Acid Morpholinoethyl Ester can cause liver damage. If you experience any symptoms of liver damage, such as yellowing of the eyes or dark urine, it is important to talk to your doctor.
Can I take Mycophenolic Acid Morpholinoethyl Ester with food?
Yes, you can take Mycophenolic Acid Morpholinoethyl Ester with food, as it can help to reduce nausea caused by the medication.
Can I take Mycophenolic Acid Morpholinoethyl Ester if I have diabetes?
Yes, you can take Mycophenolic Acid Morpholinoethyl Ester if you have diabetes. However, it is important to talk to your doctor about any other medications you are taking to manage your diabetes, as Mycophenolic Acid Morpholinoethyl Ester can interact with them.
How long does Mycophenolic Acid Morpholinoethyl Ester take to work?
Mycophenolic Acid Morpholinoethyl Ester can take up to several weeks for its full effects to be felt. Furthermore, the effects of Mycophenolic Acid Morpholinoethyl Ester can take up to several months for complete organ rejection prevention. Therefore, it is important to follow your doctor's instructions closely when taking Mycophenolic Acid Morpholinoethyl Ester.
Can I drink alcohol while taking Mycophenolic Acid Morpholinoethyl Ester?
No, it is not recommended to drink alcohol while taking Mycophenolic Acid Morpholinoethyl Ester, as drinking alcohol can increase the risk of side effects and reduce the effectiveness of the medication. It is important to talk to your doctor about any concerns you may have about drinking alcohol.
What are the long-term side effects of Mycophenolic Acid Morpholinoethyl Ester?
The long-term side effects of Mycophenolic Acid Morpholinoethyl Ester include an increased risk of infection, an increased risk of developing cancer, and an increased risk of liver, kidney, and bone marrow damage. If you experience any of these side effects, it is important to talk to your doctor.
Can I get a flu vaccine while taking Mycophenolic Acid Morpholinoethyl Ester?
Yes, you can get a flu vaccine while taking Mycophenolic Acid Morpholinoethyl Ester. However, it is important to talk to your doctor first to make sure that it is safe for you to do so.
Can Mycophenolic Acid Morpholinoethyl Ester cause muscle pain?
Yes, muscle pain is a rare side effect of Mycophenolic Acid Morpholinoethyl Ester. If you experience this, it is important to talk to your doctor.
Can Mycophenolic Acid Morpholinoethyl Ester cause anemia?
Yes, anemia is a rare side effect of Mycophenolic Acid Morpholinoethyl Ester. If you experience this, it is important to talk to your doctor.
Can I take over-the-counter medications while taking Mycophenolic Acid Morpholinoethyl Ester?
Yes, you can take some over-the-counter medications while taking Mycophenolic Acid Morpholinoethyl Ester. However it is important to talk to your doctor before taking any medications, including over-the-counter medications, vitamins, and herbal supplements.
Can I take vitamins while taking Mycophenolic Acid Morpholinoethyl Ester?
Yes, you can take some vitamins while taking Mycophenolic Acid Morpholinoethyl Ester. However, it is important to talk to your doctor before taking any medications, including vitamins, over-the-counter medications, and herbal supplements.
Can I take a non-steroidal anti-inflammatory drug (NSAID) while taking Mycophenolic Acid Morpholinoethyl Ester?
No, it is not recommended to take NSAIDs, such as ibuprofen or aspirin, while taking Mycophenolic Acid Morpholinoethyl Ester. These medications can interfere with the effectiveness of Mycophenolic Acid Morpholinoethyl Ester.
Can Mycophenolic Acid Morpholinoethyl Ester cause a decrease in white blood cell count?
Yes, Mycophenolic Acid Morpholinoethyl Ester can cause a decrease in white blood cell count, as it suppresses the body’s immune system. If you experience any symptoms of an infection, it is important to talk to your doctor.