Mirabegron

Mirabegron Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Mirabegron is a brand name. Its generic name is Mirabegron.

Mirabegron

Mirabegron is a drug used for the treatment of overactive bladder. It is a type of medication known as a beta 3 agonist, and it works by stimulating beta 3 adrenergic receptors in the bladder, which triggers bladder muscles to relax. Mirabegron helps reduce frequent urination as well as urgency and leakage associated with overactive bladder.

Uses for

Mirabegron is used to treat people who suffer from overactive bladder. It is used to treat symptoms of urine leakage, frequent urination during the day, night, and sudden urges to urinate.

Mechanism of Action

Mirabegron works by stimulating beta 3 adrenergic receptors in the bladder muscles, which signals them to relax. This helps reduce symptoms of overactive bladder such as frequent urination, urgency of urination, and leakage of urine. The drug helps to prevent involuntary contraction of the bladder muscles and improve the patient's bladder control.

How Long Does it Take to Work?

Mirabegron usually starts to work within 1 to 4 weeks after starting the medication, depending on the individual person. Most people feel relief of their symptoms within a few weeks of taking this medicine.

Absorption

Mirabegron is quickly and almost completely absorbed upon oral administration, with peak levels observed about 1.5-2 hours after administration. The drug is quickly distributed to body tissues and has a volume of distribution of 36 liters.

Route of Elimination

Mirabegron is primarily eliminated through the urine. About 65% of the drug is eliminated unchanged in the urine, and about 30% is eliminated as metabolites. About 5% of the drug is eliminated in the feces.

Dosage

Mirabegron is available in tablet form and is usually taken once daily. The recommended starting dose is 25 mg per day, taken with or without food. The dose may be increased to a maximum of 50 mg per day if needed.

Administration

Mirabegron is taken orally with or without food. It is important to take the drug as prescribed by your doctor. Do not stop taking the drug or change the dose without first consulting with your doctor.

Side Effects

Common side effects of mirabegron may include headache, dizziness, dry mouth, abdominal pain, nausea, constipation, and insomnia. Other more serious side effects include increased heart rate, changes in vision, and chest pain.

Toxicity

Even though Mirabegron is generally considered to be safe in therapeutic doses, an overdose of this medication can cause symptoms of toxicity. Overdose symptoms may include headache, dizziness, lightheadedness, fainting, flushing, visual disturbances, difficulty breathing, and increased heart rate. If these symptoms are observed, seek immediate medical attention.

Precautions

It is important to consult your doctor before taking Mirabegron if you have certain conditions, such as high blood pressure, heart problems, or if you are pregnant or breastfeeding. Mirabegron should also be used with caution in people who have kidney or liver problems, as it may worsen these conditions.

Interactions

Alcohol and other drugs may interact with Mirabegron. Tell your doctor about all the medications you are taking, including prescription and non-prescription medications, vitamins, and herbal products as they may interact with Mirabegron.

Disease Interaction

Patients with certain diseases should use Mirabegron with caution. These diseases include high blood pressure, heart problems, and kidney or liver disease. Mirabegron may worsen these medical conditions and should be taken only after consulting with your doctor.

Drug Interactions

Mirabegron may interact with certain medications, including opioids, blood pressure medicines, antibiotics, antifungals, HIV/AIDS medications, and seizure medications. Let your doctor know about any medication you are currently taking before starting Mirabegron.

Food Interactions

Mirabegron is not known to interact with food. However, it is recommended to take it with food to reduce the risk of stomach upset.

Pregnancy Use

Mirabegron is not recommended for use in pregnant women, as it may cause harm to the unborn baby. Women who are pregnant or plan on becoming pregnant should consult their doctor before taking this medication.

Lactation Use

It is unknown whether or not mirabegron is secreted in the breast milk. Therefore, breastfeeding women should consult their doctor before taking this medication.

Acute Overdose

If an acute overdose of mirabegron is suspected, a healthcare provider should be contacted immediately. Symptomatic and supportive measures should be taken as necessary.

Contraindications

Mirabegron is contraindicated in patients who are allergic to this medication, those with uncontrolled hypertension, and those who have severe coronary artery disease. It is also contraindicated in patients with severe liver impairment.

Use Directions

Mirabegron should be taken only under the guidance of your doctor. The usual recommended dose is 25-50mg once daily, taken with or without food. Do not abruptly stop taking this medication without consulting your doctor.

Storage Condition

Mirabegron should be stored at room temperature, away from direct light, moisture, and heat. Do not store in the bathroom. Keep out of the reach of children.

Volume of Distribution

The volume of distribution of Mirabegron is 36 liters.

Half Life

The half-life of Mirabegron is about 3.8 hours.

Clearance

The clearance of Mirabegron is approximately 10 litres/hour.

Here you find in details version of Mirabegron

Some Frequently Asked Questions About Mirabegron

What is Mirabegron?

Mirabegron is a prescription medication used to treat overactive bladder (OAB) in adults. It works by increasing the amount of urine your bladder can hold, which reduces your symptoms of OAB, such as sudden urges to urinate, frequent urination, and urinary incontinence.

How long does it take for Mirabegron to work?

It usually takes 2 to 4 weeks for Mirabegron to start working. However, it may take up to 8 weeks for the full effects to be seen. Since everyone responds differently to medication, the length of time until the drug starts working may vary from person to person.

What is the normal dosage of Mirabegron?

The normal dosage of Mirabegron is 50 mg taken once a day. Your doctor may adjust this dose depending on your symptoms and response to the medication.

What are the most common side effects of Mirabegron?

The most common side effects of Mirabegron include headache, dry mouth, constipation, stomach pain, and nausea. More serious side effects can include allergic reactions, vision problems, chest pain, and irregular heartbeat.

Can Mirabegron be used to treat urinary incontinence?

Yes, Mirabegron can be used to treat urinary incontinence. It works by increasing the amount of urine your bladder can hold, which reduces your symptoms of OAB, such as sudden urges to urinate, frequent urination, and urinary incontinence.

What should I do if I miss a dose of Mirabegron?

If you miss a dose of Mirabegron, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take the next dose at your regular time.

Can Mirabegron be taken with other medications?

Yes, Mirabegron may be taken with other medications. However, it is important to tell your doctor about all of the medications you are taking, as certain medications may interact with Mirabegron and cause serious side effects.

Can I drink alcohol while taking Mirabegron?

It is not recommended to drink alcohol while taking Mirabegron, as it may increase the risk of side effects or impair the effectiveness of the medication.

Is Mirabegron addictive?

No, Mirabegron is not known to be addictive. It is important to take Mirabegron as prescribed by your doctor and not to take more than the recommended dose.

What should I do if I experience side effects while taking Mirabegron?

If you experience side effects while taking Mirabegron, contact your doctor right away. Do not stop taking the medication without first talking to your doctor.

Can I take Mirabegron if I'm pregnant?

No, Mirabegron is not recommended for use by pregnant women. It is not known whether the drug can harm an unborn baby, so it is best to avoid taking the medication while pregnant.

Can I take Mirabegron if I'm breastfeeding?

No, Mirabegron is not recommended for use by breastfeeding women. It is not known whether the drug can affect breastmilk, so it is best to avoid taking the medication while breastfeeding.

Can Mirabegron be used to treat other conditions besides overactive bladder?

No, Mirabegron is not approved for use in treating any condition other than overactive bladder. It is important to talk to your doctor before taking Mirabegron for any other condition.

Does Mirabegron affect my blood pressure?

No, Mirabegron does not affect your blood pressure. However, if you have a history of high blood pressure or any other heart-related condition, it is important to talk to your doctor about the risks and benefits of taking this medication.

Will taking Mirabegron cause weight gain?

No, Mirabegron is not associated with weight gain. However, it is important to talk to your doctor if you are concerned about any changes in your weight or body fat.

Can I take Mirabegron if I have kidney problems?

No, Mirabegron is not recommended for use in people with kidney problems. Your doctor may be able to prescribe an alternative treatment if your kidney function is too impaired to take Mirabegron.

Will Mirabegron affect my kidneys?

No, Mirabegron is not known to affect the kidneys. However, if you have any questions or concerns about the effect of Mirabegron on your kidneys, it is important to talk to your doctor.

Do I need to take Mirabegron on an empty stomach?

No, Mirabegron can be taken with or without food. However, it is best to take the medication at the same time each day to maintain an even level of the drug in your body.

Can I get Mirabegron over-the-counter?

No, Mirabegron is a prescription medication and is not available over-the-counter. You must have a prescription from a doctor to be able to obtain this medication.

Is Mirabegron safe to take for a long period of time?

Yes, Mirabegron is generally considered to be safe to take for a long period of time. However, it is important to talk to your doctor about any risks or side effects that may occur with long-term use of this medication.

How should Mirabegron be stored?

Mirabegron should be stored at room temperature, away from heat and moisture. Keep the medication in a tightly closed container, and do not leave it out in the open or near any sources of heat.

What should I do if I take an overdose of Mirabegron?

If you take an overdose of Mirabegron, seek medical attention immediately. Do not take any other medication or attempt to induce vomiting.

Can Mirabegron be used by children?

No, Mirabegron is not recommended for use by children. This medication is approved only for use by adults.

Does Mirabegron cause drowsiness or sleepiness?

No, Mirabegron is not known to cause drowsiness or sleepiness. However, if you do experience these symptoms while taking Mirabegron, contact your doctor right away.

How long can Mirabegron be taken?

The length of time that Mirabegron can be taken depends on your individual condition and response to the medication. It is important to talk to your doctor about the best ways to take Mirabegron for your condition.

Is Mirabegron a controlled substance?

No, Mirabegron is not a controlled substance. It is available by prescription only, and cannot be obtained without a valid prescription from a doctor.

Can Mirabegron cause digestive problems?

Yes, Mirabegron can cause digestive problems such as stomach pain, constipation, nausea, and diarrhea. If you experience any of these side effects while taking Mirabegron, contact your doctor right away.

Can Mirabegron cause frequent urination?

Yes, Mirabegron can cause frequent urination. However, this is actually the desired effect of the drug, as it helps to reduce the symptoms of overactive bladder such as sudden urges to urinate and urinary incontinence.

What other conditions can Mirabegron be used for?

Mirabegron is only approved for use in treating overactive bladder. It is not approved for use in treating any other condition, and it is important to talk to your doctor before taking Mirabegron for something other than overactive bladder.

Can Mirabegron be taken with high blood pressure medication?

Yes, Mirabegron can be taken with high blood pressure medication. However, it is important to tell your doctor about all of the medications you are taking, as certain medications may interact with Mirabegron and cause serious side effects.

Does Mirabegron increase blood sugar levels?

No, Mirabegron is not known to increase blood sugar levels. However, if you have diabetes or are at risk of developing diabetes, it is important to tell your doctor about this before taking this medication.

Does Mirabegron cause impotence?

No, Mirabegron is not known to cause impotence. However, if you experience impotence while taking Mirabegron, contact your doctor right away.

Does Mirabegron treat other bladder conditions besides overactive bladder?

No, Mirabegron is approved for the treatment of overactive bladder only. It is not approved for treatment of any other bladder condition, and it is important to talk to your doctor before taking the drug for something other than overactive bladder.

Does Mirabegron cause constipation?

Yes, Mirabegron can cause constipation. If you experience constipation while taking Mirabegron, contact your doctor right away.

Does Mirabegron cause blurred vision?

Yes, Mirabegron can cause blurred vision. If you experience blurred vision while taking Mirabegron, contact your doctor right away.

Can Mirabegron be taken with other bladder medications?

Yes, Mirabegron can be taken with other bladder medications. However, it is important to talk to your doctor about all of the medications you are taking, as certain medications may interact with Mirabegron and cause serious side effects.

Can Mirabegron be used to treat frequent urination?

Yes, Mirabegron can be used to treat frequent urination. It works by increasing the amount of urine your bladder can hold, which reduces your symptoms of OAB, such as sudden urges to urinate, frequent urination, and urinary incontinence.

Can Mirabegron cause headaches?

Yes, Mirabegron can cause headaches. If you experience headaches while taking Mirabegron, contact your doctor right away.

Can Mirabegron be taken with anticholinergic medications?

Yes, Mirabegron can be taken with anticholinergic medications. However, it is important to talk to your doctor about all of the medications you are taking, as certain medications may interact with Mirabegron and cause serious side effects.

What are the long-term effects of taking Mirabegron?

The long-term effects of taking Mirabegron are not known. It is important to talk to your doctor about any risks or side effects that may occur with long-term use of this medication.

Can Mirabegron be taken with diuretics?

Yes, Mirabegron can be taken with diuretics. However, it is important to talk to your doctor about all of the medications you are taking, as certain medications may interact with Mirabegron and cause serious side effects.

Can Mirabegron be taken with blood pressure medication?

Yes, Mirabegron can be taken with blood pressure medication. However, it is important to tell your doctor about all of the medications you are taking, as certain medications may interact with Mirabegron and cause serious side effects.