Menotropins (FSH;LH)
Menotropins (FSH;LH) Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Menotropins (FSH;LH) is a brand name. Its generic name is Menotropins.
Meaning
Menotropins (FSH;LH) are a type of medication that contain follicle stimulating hormone (FSH) and luteinizing hormone (LH) and are used to stimulate the production of more than one egg in women during certain fertility procedures.
Uses
Menotropins (FSH;LH) are used to stimulate ovulation (the release of the egg from the ovary) and treat infertility in women. It is used in conjunction with other fertility treatments, such as in-vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI).
Mechanism of Action
Menotropins (FSH;LH) stimulate the egg follicles located in the ovary to produce more than one egg. FSH stimulates the growth and development of the follicles, while LH stimulates the release of the egg from the follicle. This combination of hormones is important in stimulating the egg follicles and ultimately producing the eggs necessary for fertility treatments.
How long does it take to work?
Menotropins (FSH;LH) typically take 7-14 days to stimulate the ovaries and produce the eggs necessary for fertility treatments.
Absorption
Menotropins (FSH;LH) are injected into the body and absorbed through the skin at the injection site.
Route of Elimination
Menotropins (FSH;LH) are broken down by the liver and eliminated from the body through the urine.
Dosage
The starting dose of menotropins varies based on the patient's age and ovarian reserve. The usual starting dose is 75-150 units administered daily by subcutaneous injection for 7 to 14 days. The dose may be increased or decreased depending on how the patient responds and the results of monitoring.
Administration
Menotropins (FSH;LH) are administered by subcutaneous injection. A doctor will teach the patient how to give the injections and the patient should follow the instructions closely.
Side Effects
- Hot flashes
- Fatigue
- Breast tenderness
- Fluid retention
- Headache
- Nausea/vomiting
- Visual disturbances
- Depression
- Ovarian Hyperstimulation Syndrome (OHSS)
Toxicity
Menotropins (FSH;LH) are generally well-tolerated at the recommended dosage. However, an overdose of the medication could cause an increase in side effects and should be avoided.
Precautions
- Women should not use menotropin if they are pregnant.
- It should be used with caution in women with a history of ovarian cysts or abnormal uterine bleeding.
- Menotropins (FSH;LH) can cause a decrease in potassium levels, so blood tests should be done to monitor potassium levels.
- Women should follow a strict follicle monitoring schedule during the treatment.
- Women should not take menotropin if they are allergic to it or any of its ingredients.
Interactions
Menotropins (FSH;LH) may interact with other medications, herbs, or supplements that increase or decrease its effectiveness. Some medicines and supplements that may interact with menotropins include: leuprolide, goserelin, cabergoline, melatonin, vitamin E, omega-3 fatty acid supplements, thiamine, and glucosamine.
Disease Interactions
Menotropins (FSH;LH) should be used with caution in women with a history of ovarian cysts or abnormal uterine bleeding.
Drug Interactions
Menotropins (FSH;LH) may interact with other medications, such as leuprolide, goserelin, cabergoline, and melatonin. It is important to inform your doctor of all medications, both prescription and over-the-counter, that you are taking before using menotropins.
Food Interactions
Menotropins (FSH;LH) may interact with certain foods or herbal supplements, so before taking menotropins it is important to inform your doctor of all food items, vitamins, and herbal supplements that you are taking.
Pregnancy Use
Menotropins (FSH;LH) should not be used during pregnancy. It can increase the risk of multiple births and birth defects.
Lactation Use
Menotropins (FSH;LH) are not recommended for use during lactation. It can increase the risk of multiple births and birth defects.
Acute Overdose
An overdose of menotropins can increase the risk of serious side effects and should be avoided. Symptoms of an overdose may include vomiting, nausea, pain in the abdomen, chest pain, and rapid pulse.
Contraindications
- Women who are pregnant or breastfeeding should not use menotropins.
- Women with certain conditions, such as ovarian cancer, liver disease or abnormal uterine bleeding should not use menotropins.
- Women with a history of ovarian cysts should not use menotropins.
- Women with an allergy to any of the ingredients in menotropins should not use the medication.
Use Directions
Menotropins (FSH;LH) should be injected into the skin of the abdomen or thigh area, as directed by your doctor. A doctor will guide you on how to properly inject the medication. Make sure to follow the instructions closely to avoid any complications or side effects.
Storage Conditions
Menotropins (FSH;LH) should be stored in the refrigerator or at room temperature, as directed by your doctor. It should also be kept out of direct sunlight and away from heat, moisture, and children.
Volume of Distribution
Menotropins (FSH;LH) have a volume of distribution of approximately 3.1 liters per kilogram.
Half Life
The half-life of menotropins is approximately 15-25 hours.
Clearance
The clearance of menotropins is approximately 0.17 liters per hour per kilogram.
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