Melfiat
Melfiat Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Melfiat is a brand name. Its generic name is Phendimetrazine.
Introduction
Melfiat is a sympathomimetic amine. It was originally approved by the Food and Drug Administration (FDA) as an appetite suppressant for the short-term treatment of obesity.Uses
Melfiat is used in the short-term management of exogenous obesity. It is used in combination with an individually tailored diet plan as part of a total weight-loss program.Mechanism of Action
Melfiat works by increasing certain neurotransmitters and hormones, including dopamine, epinephrine, and norepinephrine. This stimulates the hypothalamus, impacts hunger signals, and help to reduce appetite and calorie intake.How Long Does It Take to Work?
The effects of Melfiat should be noticed within an hour of taking the medication. The maximum effect can be felt about three hours after taking the medication.Absorption
Melfiat is rapidly absorbed from the gastrointestinal tract after oral administration. The peak plasma concentration may vary from about 0.2 to 1.4 mcg/ml.Route of Elimination
Melfiat is metabolized primarily by the liver. The metabolites are excreted in the urine and some are excreted in the feces.Dosage
Melfiat is available in a variety of dosage forms (e.g., tablets, capsules, and other solid dosage forms). The recommended dose for adults is 35 mg and 105 mg daily taken in 1–3 divided doses 30 minutes before meals. The daily dose should not exceed 105 mg.Administration
Melfiat should be administered orally, either dissolved in water or taken with food. Do not crush or chew the tablets.Side Effects
Common side effects of Melfiat include dry mouth, insomnia, nervousness, restlessness, blurred vision, dizziness, constipation, nausea, vomiting, and headaches.Toxicity
Melfiat has a low potential for toxicity. Overdose can be fatal, and symptoms may include convulsions, loss of consciousness, and coma.Precautions
Phenemtrazine should not be used in pregnant or nursing women. Those with a history of substance abuse or cardiovascular disease should also avoid using this medication.Interactions
Phenemtrazine may interact with other medications, including sedatives, monoamine oxidase inhibitors, tricyclic antidepressants, and opioid analgesics.Disease Interaction
Patients with a history of hyperthyroidism, hypertension, diabetes, or glaucoma should not take this medication. It should also be used with caution in those with a history of drug dependence or alcohol abuse.Drug Interaction
Phenemtrazine may interact with other drugs, including opioid analgesics, tricyclic antidepressants, monoamine oxidase inhibitors, and sedatives.Food Interactions
Melfiat should not be taken with alcohol or any other medication. Food should be consumed at least an hour after taking the medication in order to maximize results.Pregnancy Use
Melfiat should be avoided in pregnant women.Lactation Use
Melfiat should not be used by nursing mothers.Acute Overdose
Acute overdoses of Melfiat can be fatal. Symptoms of acute overdose include convulsions, loss of consciousness, and coma.Contraindication
Melfiat is contraindicated in pregnant and nursing women. It is also contraindicated in individuals with drug dependence or alcohol abuse.Use Direction
Melfiat should be taken according to doctor’s instructions. Do not crush or chew the tablets.Storage Condition
Tablets should be stored at room temperature, out of reach of children.Volume of Distribution
Melfiat is highly bound to plasma proteins.Half-Life
The half-life of Melfiat is approximately one to four hours.Clearance
The clearance of Melfiat is approximately 25 to 30 mL/min.Here you find in details version of Melfiat
Some Frequently Asked Questions About Melfiat
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