Bontril PDM
Bontril PDM Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Bontril PDM is a brand name. Its generic name is Phendimetrazine.
Introduction
Bontril PDM is a sympathomimetic amine. It was originally approved by the Food and Drug Administration (FDA) as an appetite suppressant for the short-term treatment of obesity.Uses
Bontril PDM is used in the short-term management of exogenous obesity. It is used in combination with an individually tailored diet plan as part of a total weight-loss program.Mechanism of Action
Bontril PDM works by increasing certain neurotransmitters and hormones, including dopamine, epinephrine, and norepinephrine. This stimulates the hypothalamus, impacts hunger signals, and help to reduce appetite and calorie intake.How Long Does It Take to Work?
The effects of Bontril PDM should be noticed within an hour of taking the medication. The maximum effect can be felt about three hours after taking the medication.Absorption
Bontril PDM is rapidly absorbed from the gastrointestinal tract after oral administration. The peak plasma concentration may vary from about 0.2 to 1.4 mcg/ml.Route of Elimination
Bontril PDM is metabolized primarily by the liver. The metabolites are excreted in the urine and some are excreted in the feces.Dosage
Bontril PDM is available in a variety of dosage forms (e.g., tablets, capsules, and other solid dosage forms). The recommended dose for adults is 35 mg and 105 mg daily taken in 1–3 divided doses 30 minutes before meals. The daily dose should not exceed 105 mg.Administration
Bontril PDM should be administered orally, either dissolved in water or taken with food. Do not crush or chew the tablets.Side Effects
Common side effects of Bontril PDM include dry mouth, insomnia, nervousness, restlessness, blurred vision, dizziness, constipation, nausea, vomiting, and headaches.Toxicity
Bontril PDM has a low potential for toxicity. Overdose can be fatal, and symptoms may include convulsions, loss of consciousness, and coma.Precautions
Phenemtrazine should not be used in pregnant or nursing women. Those with a history of substance abuse or cardiovascular disease should also avoid using this medication.Interactions
Phenemtrazine may interact with other medications, including sedatives, monoamine oxidase inhibitors, tricyclic antidepressants, and opioid analgesics.Disease Interaction
Patients with a history of hyperthyroidism, hypertension, diabetes, or glaucoma should not take this medication. It should also be used with caution in those with a history of drug dependence or alcohol abuse.Drug Interaction
Phenemtrazine may interact with other drugs, including opioid analgesics, tricyclic antidepressants, monoamine oxidase inhibitors, and sedatives.Food Interactions
Bontril PDM should not be taken with alcohol or any other medication. Food should be consumed at least an hour after taking the medication in order to maximize results.Pregnancy Use
Bontril PDM should be avoided in pregnant women.Lactation Use
Bontril PDM should not be used by nursing mothers.Acute Overdose
Acute overdoses of Bontril PDM can be fatal. Symptoms of acute overdose include convulsions, loss of consciousness, and coma.Contraindication
Bontril PDM is contraindicated in pregnant and nursing women. It is also contraindicated in individuals with drug dependence or alcohol abuse.Use Direction
Bontril PDM should be taken according to doctor’s instructions. Do not crush or chew the tablets.Storage Condition
Tablets should be stored at room temperature, out of reach of children.Volume of Distribution
Bontril PDM is highly bound to plasma proteins.Half-Life
The half-life of Bontril PDM is approximately one to four hours.Clearance
The clearance of Bontril PDM is approximately 25 to 30 mL/min.Here you find in details version of Bontril PDM
Some Frequently Asked Questions About Bontril PDM
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