Lozicum

Lozicum Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Lozicum is a brand name. Its generic name is Lorazepam.

Introduction of Lozicum

Lozicum is a benzodiazepine medication that is commonly used to treat a variety of conditions, including anxiety, alcohol withdrawal, or seizures. It is available in both orally administered tablet and injectable form. It depresses the central nervous system and is used as a sedative, for muscle relaxation, and to control seizures.

Uses for Lozicum

Lozicum is mainly used to treat anxiety, insomnia, seizure disorders, muscle related disorders or issues with alcohol withdrawal. It can also be used as a sedative before medical procedures.

Mechanism of Action

Lozicum works by affecting the brain's GABA receptors, which increases the effects of GABA (gamma-aminobutyric acid). It causes the brain to become more relaxed and calm.

How Long Does it Take to Work

The effects of lorazepam may appear within 20 minutes of taking the medication. Its effects may last up to 6 hours after taking the medication.

Absorption

Lozicum is well absorbed when taken by mouth and its absorption is not affected by food.

Route of Elimination

Lozicum is eliminated mainly through the kidneys as unchanged (active) drug.

Dosage

The usual adult dosage of lorazepam ranges from 0.5 to 2 mg per day, taken two to three times a day. It is recommended to start at the lowest possible dose and gradually increase it to the desired effect.

Administration

Lozicum can be taken orally (in tablet form) or can be injected intramuscularly.

Side Effect

Common side effects of lorazepam include drowsiness, dizziness, confusion, headache, weakness, drymouth, coordination problems. More serious side effects may include changes in behavior or depression.

Toxicity

Overdosing on lorazepam can be dangerous and may result in respiratory depression, coma, or death.

Precautions

Before taking lorazepam, it is important to inform your doctor of your full medical history as well as any medications that you are currently taking. People with certain medical conditions, such as severe liver or kidney disease, may not be able to take lorazepam.

Interactions

Lozicum may interact with a variety of medications, including antihistamines, antidepressants, and antipsychotics. It can also interact with alcohol, as well as certain herbal supplements.

Disease Interactions

Lozicum should be used with caution in people with certain underlying illnesses, such as glaucoma, asthma, or depression. It can also affect people with liver or kidney disease, or chronic respiratory diseases.

Drug Interactions

Lozicum should not be used in combination with certain other medications and substances, including alcohol and certain opioids.

Food Interactions

Food does not appear to significantly affect the absorption of lorazepam.

Pregnancy Use

Lozicum is a category D drug in pregnant women and should not be taken during pregnancy. If taken in the third trimester, it may cause neonatal respiratory depression.

Lactation Use

It is not known if lorazepam is excreted into human milk. Therefore, breastfeeding is usually not recommended during treatment with lorazepam.

Acute Overdose

Signs and symptoms of acute overdose with lorazepam include confusion, impaired coordination, oversedation, and respiratory depression. If overdose occurs, contact a poison control center immediately.

Contraindications

Lozicum is contraindicated in people with a known hypersensitivity to benzodiazepines. It should not be taken by people with a history of drug abuse.

Use Directions

Lozicum should be taken as prescribed by your doctor. Follow the instructions on the label. Do not take more or less than the prescribed dose. Do not stop taking the medication suddenly as this may cause withdrawal symptoms.

Storage Condition

Lozicum should be stored in a cool, dry place at room temperature and protected from light.

Volume of Distribution

The volume of distribution (Vd) is the amount of lorazepam that enters the bloodstream after being administered. The Vd of lorazepam is 1-2 L/kg.

Half Life

The half-life of lorazepam is 12-18 hours. This indicates how long it takes for the drug to be reduced by half in your system.

Clearance

The clearance of lorazepam is 0.5-1 L/hr/kg. This indicates how quickly the drug is eliminated from your system.

Here you find in details version of Lozicum

Some Frequently Asked Questions About Lozicum

What is Lozicum?

Lozicum is a powerful benzodiazepine that is most commonly used to treat a range of anxiety disorders.

What is the usual recommended dosage for Lozicum?

The usual starting recommended dose for adults is 2 mg to 4 mg per day, given in divided doses.

What are the side effects of Lozicum?

Common side effects of Lozicum include drowsiness, lightheadedness, confusion, dizziness, and appetite and weight changes.

What are the most common uses for Lozicum?

Lozicum is most commonly used to treat anxiety disorders, seizures, and trouble sleeping (insomnia).

Is Lozicum addictive?

Lozicum is a potentially addictive medication. It is important to take Lozicum as prescribed to minimize the risk of addiction.

What is the difference between Lozicum and Xanax (Alprazolam)?

Lozicum and Xanax both belong to the same family of drugs (benzodiazepines) and have similar effects. Lozicum has a longer half-life than Xanax, meaning that it has a longer-lasting effect.

What should I do if I miss a dose of Lozicum?

If you miss a dose of Lozicum, take it as soon as you remember, unless it is close to the time for your next dose. In that case, skip the missed dose and take the next dose as usual.

What should I avoid while taking Lozicum?

You should avoid drinking alcohol, operating heavy machinery or driving while taking Lozicum, as it can potentiate the effects of Lozicum and increase the risk of adverse reactions.

Can Lozicum be taken with other medicines?

Lozicum may interact with certain other medicines, and so it is important to talk to your doctor before taking any other medicines while taking Lozicum.

Are there any alternatives to Lozicum?

There are several alternatives to Lozicum, including other anti-anxiety medications, cognitive-behavioral therapy, and relaxation techniques.

How quickly does Lozicum work?

The effects of Lozicum usually begin within 20 minutes of taking the medication and typically last for 3 to 8 hours.

What other conditions can Lozicum be used for?

Lozicum can be used to treat a variety of conditions, including epilepsy, alcohol withdrawal syndrome, and nausea and vomiting associated with cancer chemotherapy.

What is the shelf life of Lozicum?

The shelf life of Lozicum tablets is 3 to 5 years from the date of manufacture, and the shelf life of injectable Lozicum is 2 years from the date of manufacture.

Can Lozicum be taken while pregnant or breastfeeding?

Lozicum is not recommended for use in pregnant or breastfeeding women, due to potential risks to the fetus or infant.

Can I become resistant to Lozicum?

Over time, some people can become resistant to the effects of Lozicum, meaning that higher doses are needed to achieve the same effects. If this occurs, your doctor may suggest trying an alternative treatment.

Is Lozicum safe for long-term use?

Long-term use of Lozicum can lead to tolerance, dependence, and potential withdrawal symptoms if the medication is suddenly stopped. Therefore, Lozicum should only be taken as prescribed by a doctor.

When should Lozicum not be taken?

Lozicum should not be taken if you have a severe liver or kidney condition, or if you are allergic to benzodiazepines.

Are there any special instructions for taking Lozicum?

You should avoid alcohol and other CNS depressants while on Lozicum, and make sure to take it exactly as prescribed.

What are the common side effects of short-term use of Lozicum?

Common side effects of short-term use of Lozicum include drowsiness, lightheadedness, confusion, dizziness, and appetite and weight changes.

What are the common side effects of long-term use of Lozicum?

Common side effects of long-term use of Lozicum include memory impairment, difficulty concentrating, difficulty with coordination and balance, and depression.

Can Lozicum be taken with other medications?

Lozicum may interact with certain medications and should not be taken with other medications without consulting your doctor.

Can Lozicum be used to treat panic attacks?

Lozicum can sometimes be used to treat panic attacks, although there are other options that may be more effective.

What happens if I take an overdose of Lozicum?

An overdose of Lozicum can lead to serious symptoms and even death. If you or someone you know has taken an overdose, call 911 or contact your local poison control center.

Can Lozicum be used to treat insomnia?

Yes, Lozicum can be used to treat insomnia. However, it should only be used for short-term use, as longer use can cause rebound insomnia.

What are the withdrawal symptoms of Lozicum?

Withdrawal symptoms of Lozicum can include anxiety, insomnia, nausea, muscle pain, irritability, and hallucinations.

Is there a safe way to taper off Lozicum?

If you want to stop taking Lozicum, it is important to work with your doctor or psychiatrist to slowly and safely lower your dose over time in order to avoid potential withdrawal symptoms.

Can Lozicum be used to treat bipolar disorder?

Lozicum can be used for short-term treatment of extreme symptoms of bipolar disorder. However, it is usually not a recommended long-term treatment.

How long does Lozicum stay in your system?

The half-life of Lozicum is approximately 10 to 20 hours, meaning that it takes 10 to 20 hours for the body to remove half of the dose from the bloodstream.

Can Lozicum be used to treat ADHD?

No, Lozicum is not indicated for the treatment of ADHD and should not be used to treat ADHD.

What is the recommended starting dose for children taking Lozicum?

The recommended starting dose for children taking Lozicum is 0.05 mg/kg/day, given in divided doses.

Can I drink alcohol while taking Lozicum?

No, you should not drink alcohol while taking Lozicum, as the combination can increase the risk of serious side effects.

Can Lozicum cause weight gain?

Lozicum can cause weight gain as a side effect. If you are concerned about weight gain, it is important to talk to your doctor.

Can Lozicum be used to treat anxiety?

Yes, Lozicum is commonly used to treat anxiety disorders. It is important to talk to your doctor before taking Lozicum for anxiety.

Does Lozicum cause brain fog?

Yes, Lozicum can cause brain fog, as well as other cognitive side effects such as difficulty concentrating and memory loss.

When should I take Lozicum?

Lozicum should be taken exactly as prescribed by your doctor. Most commonly, it is taken several times a day as needed for anxiety or insomnia.

Can Lozicum help with migraine headaches?

Lozicum is sometimes used for acute treatment of migraine headaches. It should only be used for this purpose if recommended by your doctor.

Can Lozicum be used to treat muscle spasms?

Yes, Lozicum is occasionally used to treat muscle spasms and seizure activity. It should only be used for this purpose if recommended by your doctor.

Does Lozicum cause sleep apnea?

Yes, Lozicum can cause sleep apnea, as well as other sleep disturbances such as daytime drowsiness.

Can I take Lozicum if I have asthma?

Lozicum can cause respiratory depression and should be used with caution in people with asthma. It is important to talk to your doctor before starting Lozicum.

Does Lozicum interact with any foods?

No, Lozicum does not interact with any foods, but it is important to avoid drinking alcohol while taking Lozicum.

Can Lozicum be used to treat pain?

Yes, Lozicum can be used to treat certain types of pain, but it is usually prescribed as an adjunctive therapy and not as a standalone treatment.

What is the proper way to store Lozicum?

Lozicum should be stored in a tightly closed container at room temperature (15 to 30 degrees Celsius) away from light and children.