Lisurida
Lisurida Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Lisurida is a brand name. Its generic name is Lisuride.
Introduction
Lisurida is an antiparkinsonian and anti-smooth-muscle drug used to treat Parkinson’s disease. It belongs to the class of drugs known as ergoline derivatives or dopamine receptor agonists. It was first approved in the United States in 1994.Uses For
Lisurida is an antiparkinsonian and anti-smooth-muscle drug used to treat Parkinson’s disease. It works by stimuating both D2 and D3 dopamine receptors with similar efficacy as bromocriptine and cabergoline. It also increases the synthesis and release of dopamine in the striatal area which can reduce the motor symptoms of Parkinson’s disease.Mechanism Of Action
Lisurida binds to dopamine receptors in the brain, which stimulates the central dopamine system and increases dopamine release. This increase in dopamine leads to the suppression of the abnormal movements associated with Parkinson’s. The exact mechanism of action is not fully understood.How Long Does It Take To Work?
Studies have shown that Lisurida can take up to four weeks to be effective in reducing the motor symptoms of Parkinson’s. It is important to remember that it is a slow-acting drug, so it may take some time to see results.Absorption
Lisurida is well absorbed with a bioavailability of 64%. Food does not significantly affect its absorption.Route Of Elimination
Lisurida is metabolized in the liver by phase I and II enzymes and is eliminated mainly in the urine.Dosage
The usual starting dosage of lisuride is 0.2 to 0.4 mg per day, divided into 2 or 3 doses. The dosage may then be increased by 0.2 to 0.4mg per day every two weeks up to a maximum of 5.6 to 7.2 mg per day. For maintenance therapy, doses of 1.8 to 2.4 mg per day are generally appropriate for most patients.Administration
Lisurida is taken orally, usually in the form of a tablet. It should be taken with or without food.Side Effect
Common side effects of lisuride include nausea, vomiting, dizziness, headache, blurred vision. It may also cause drowsiness. Less common side effects include constipation, excessive sweating, dry mouth, reversible mental confusion, incoordination, restlessness and emotional swings.Precaution
Lisurida should be used with caution in people with a history of glaucoma, psychosis, or mania. It may also exacerbate psychotic symptoms. Lisurida should not be used by women who are pregnant or lactating.Interaction
Lisurida may interact with other medications, including certain antipsychotics, antacids, MAO inhibitors, and antibiotics. Therefore, it is important to tell your healthcare provider know all the medications you are taking.Disease Interaction
Lisurida may worsen symptoms of psychosis or mania in people with a history of these conditions. It should be used with caution in people with glaucoma, as it may worsen the condition.Drug Interaction
Lisurida may interact with certain medications, such as antibiotics, MAO inhibitors, and antacids. Therefore, it is important to make sure your healthcare provider is aware of all the medications you are taking.Food Interactions
Food has no effect on the absorption of lisuride. It can, however, interact with certain foods, such as high-protein or high-fat foods. Therefore, it is important to check with your healthcare provider if you are taking lisuride and eating certain foods.Pregnancy Use
Lisurida is not recommended for use in pregnant women, as the effects on the fetus are unknown.Lactation Use
Lisurida is not recommended for use in lactating women, as the effects on the infant are unknown.Acute Overdose
An acute overdose of lisuride is unlikely to cause life-threatening effects. However, symptoms may include drowsiness, confusion, weakness, dizziness, nausea, and blurred vision.Contraindication
Lisurida is contraindicated in people with a history of psychosis, mania, or glaucoma. It is also contraindicated in women who are pregnant or lactating.Use Direction
Lisurida must be taken exactly as prescribed by your physician. Make sure to tell your healthcare provider about all the medications you are taking, and never stop taking lisuride without consulting your doctor.Storage Conditions
Lisurida should be stored at room temperature, away from heat, moisture, and direct light. It should not be stored in the bathroom or kitchen.Volume Of Distribution
The volume of distribution for lisuride is about 1000 L.Half Life
The half-life of lisuride is 3 to 6 hours.Clearance
The clearance of lisuride is approximately 500 ml/min.Here you find in details version of Lisurida
Some Frequently Asked Questions About Lisurida
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