Laxan

Laxan Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Laxan is a brand name. Its generic name is Lactulose.

Laxan

Laxan is a synthetic combination of two naturally-occurring sugars, glucose and galactose. It is used as a laxative to treat constipation and to reduce hepatic encephalopathy. The mechanism of action of lactulose is not fully understood, but it appears to either displace toxins or increase stool water content or both. Laxan can take up to 72 hours to take effect.

Absorption and Route of Elimination

Absorption of lactulose is incomplete, so most of it passes through the intestine without being absorbed. It is fermented by bacteria in the digestive tract absorbs some of it. The remainder, usually discharged in the stools, is metabolized by bacteria in the large intestine to lactic and acetic acids. These metabolites are rapidly absorbed and metabolized by the body.

Dosage and Administration

The recommended dosage of lactulose is 15-45ml per day (15mL for children under 2 years of age). It should be taken in three or four divided doses with 1-2 hours between doses, and on an empty stomach. Laxan can be taken with water, fruit juice, or milk.

Side Effects, Toxicity, and Precaution

The most common side effects of lactulose are stomach cramping, bloating, and diarrhea. It can also cause electrolyte disturbances, vitamin deficiencies, and dehydration. Laxan should be used with caution in patients with hepatic encephalopathy, as it may increase the level of ammonia in the blood. It should not be used in patients with severe electrolyte disturbance, malabsorption, or certain severe gastrointestinal diseases. It should also be used with caution in pregnant and lactating women.

Interaction

Laxan may interact with some medications, including laxatives, antibiotics, antacids, and other drugs that decrease peristalsis. It should also not be taken with oral vitamins and minerals, as it may decrease their absorption.

Disease Interactions

Laxan may worsen symptoms of some diseases, including renal impairment, intestinal obstruction, colitis, and Crohn's disease. It should also not be used in patients with diabetic ketoacidosis.

Drug Interactions

Laxan may reduce the absorption of some medications, including antibiotics, oral vitamin and mineral supplements, and antacids. It may also interfere with the effect of certain drugs, such as lithium and some cancer medications.

Food Interactions

Laxan may interact with some foods, including dairy products, and foods containing sorbitol. It is recommended to avoid these foods when taking lactulose.

Pregnancy and Lactation Use

Laxan is generally considered safe for pregnant and lactating women. However, it is recommended to consult with a healthcare professional before taking this medication during pregnancy or lactation.

Acute Overdose

An acute overdose of lactulose may lead to watery stools, electrolyte imbalance, abdominal pain, and nausea or vomiting. It is recommended to seek medical help if a person experiences any of these symptoms.

Contraindication

Laxan is contraindicated in patients with known hypersensitivity to it or any other components of its formulation, as well as in patients with severe electrolyte disturbances, malabsorption, and certain gastrointestinal diseases.

Use Direction

Laxan should be taken as directed by a healthcare professional. Generally, it is recommended to take 15-45ml (15mL for children under 2 years of age) with 1-2 hours between doses, on an empty stomach.

Storage Conditions

The drug should be stored in tightly closed containers in room temperature away from heat and moisture.

Volume of Distribution

Laxan is not highly lipophilic and thus not expected to distribute into the central nervous system. The volume of distribution is up to 10-20 L/kg.

Half Life

The elimination half-life is approximately 6.2 hours.

Clearance

The clearance of lactulose is about 0.1 L/hr/kg.

Here you find in details version of Laxan

Some Frequently Asked Questions About Laxan

What is Laxan?

Laxan is a non-digestible disaccharide sugar used as a medication and probiotic. Laxan is prescribed to treat constipation and hepatic encephalopathy. It is also used to prevent fecal impaction.

How does Laxan work?

Laxan works by decreasing the amount of ammonia in the gut and increasing the amount of fecal water in the bowels to make the stools softer and easier to pass. It also increases the amount of beneficial bacteria in the gut, which helps to reduce the amount of ammonia produced.

What are the possible side effects of taking Laxan?

The possible side effects of taking Laxan include bloating, gas, stomach cramps, and diarrhea. Rarely, more serious side effects such as low blood potassium levels, rapid heartbeat, and changes in blood glucose levels may occur. Be sure to talk to your doctor if any of these side effects occur.

What is the recommended dosage for adults taking Laxan?

The recommended dose for adults taking Laxan is 15-45 ml once or twice per day. Dosage needs to be adjusted according to response and effects.

How should I take Laxan?

Laxan should be taken with a full glass of water. It can also be mixed with other liquids such as juice or coffee. Laxan should be taken on an empty stomach or at least 1 hour before or 2 hours after a meal.

Can I take Laxan with other medications?

You should always consult your doctor before taking Laxan with other medications. Laxan may interact with other medications so it is best to discuss any potential interactions with your doctor before taking it.

What if I forget to take my dose of Laxan?

If you forget to take your dose of Laxan, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and take your regular dose at the usual time.

Is Laxan safe to take during pregnancy?

Laxan is considered safe to take during pregnancy, but should only be taken under a doctor’s supervision. Be sure to discuss any potential risks or interactions with your doctor.

Can children take Laxan?

Laxan is not recommended for children under the age of 2 years. Children over the age of 2 years may take Laxan but should do so only under the supervision of a doctor.

What are the common minor side effects of taking Laxan?

The common minor side effects of taking Laxan include stomach cramps, bloating, gas, and diarrhea. If any of these side effects become severe or do not go away, contact your doctor.

Can I drink alcohol while taking Laxan?

Alcohol may interfere with the effectiveness of Laxan. If you are taking Laxan, it is best to avoid or limit alcohol consumption.

What should I do if I experience severe side effects while taking Laxan?

If you experience severe side effects such as nausea, vomiting, dizziness, lightheadedness, rapid heartbeat, changes in blood glucose levels and/or low blood potassium levels, stop taking Laxan and contact your doctor immediately.

Can I take Laxan with antacids or laxatives?

It is not recommended to take Laxan with antacids or laxatives. If you are taking either of these medications, discuss them with your doctor before taking Laxan.

Can people with diabetes take Laxan?

People with diabetes may take Laxan, however it is recommended to monitor their blood sugar levels closely as it may have an effect on levels. It is best to discuss any potential interactions with a doctor before taking Laxan.

Is Laxan a laxative?

Laxan is not technically a laxative, but it is used to relieve constipation because it softens the stool and helps it pass more easily. It is therefore considered a type of softener.

Can I take other medications while taking Laxan?

You should always consult your doctor before taking any other medications while taking Laxan. Laxan may interact with other medications, so it is best to discuss any potential interactions with your doctor before taking it.

Can Laxan be used to treat diarrhea?

Laxan may be used to treat some types of diarrhea, however it is important to speak with your doctor first to discuss the most appropriate treatment. Taking too much lactulose can also cause diarrhea.

What are the long-term effects of taking Laxan?

The long-term effects of taking Laxan depend on the dosage and individual. The most common long-term effects are bloating, gas, and loose stools. Long-term use of Laxan may also lead to gastritis, electrolyte disturbances, and cholelithiasis (gallstones). Speak to your doctor if you have any concerns.

Can Laxan be used to treat constipation?

Yes, Laxan is often used to treat constipation by softening the stool and encouraging movement of the bowels. It is usually taken as a single dose at the same time each day.

What is the best time to take Laxan?

The best time to take Laxan is with a full glass of water either on an empty stomach or at least 1 hour before or 2 hours after a meal.

Should I take Laxan in the morning or evening?

The best time to take lactulose will depend on the individual. Some people may find that it works better for them if they take it in the morning, whereas others may prefer to take it in the evening.

Can Laxan be used for weight loss?

Laxan is not typically used for weight loss and there is no evidence to suggest that it can help with weight loss. It is best to speak to your doctor if you are considering taking a lactulose to aid weight loss.

What are the benefits of taking Laxan?

The main benefit of taking Laxan is that it is a non-digestible sugar used to treat constipation, hepatic encephalopathy and prevent fecal impaction. It works by decreasing the amount of ammonia in the gut and increasing the amount of fecal water in the bowels to make the stools softer and easier to pass. It also increases the amount of beneficial bacteria in the gut, which helps to reduce the amount of ammonia produced.

Can Laxan be used to reduce ammonia levels in the body?

Yes, Laxan is often used to reduce ammonia levels in the body by decreasing the amount of ammonia in the gut and increasing the amount of fecal water in the bowels to make the stools softer and easier to pass. It also increases the amount of beneficial bacteria in the gut, which helps to reduce the amount of ammonia produced.

Is there a generic form of Laxan available?

Yes, some generic forms of Laxan are available. It is best to speak to your doctor or pharmacist to determine which form is best for you.

Does Laxan have any potential interactions with other medications?

Yes, Laxan may have potential interactions with other medications. It is important to talk to your doctor or pharmacist before taking any other medications while taking lactulose.

Will Laxan cause bloating or gas?

Yes, bloating and gas are common side effects of taking Laxan. If these side effects become severe or do not go away, contact your doctor.

How long does it take Laxan to work?

The amount of time it takes for Laxan to work varies from person to person. In general, it takes around 6-8 hours for Laxan to start having an effect.

Are there any foods I should avoid while taking Laxan?

It is not generally recommended to avoid any specific foods while taking Laxan but it is best to speak to your doctor or pharmacist for advice on foods that could interfere with its effectiveness.

What is the active ingredient in Laxan?

The active ingredient in Laxan is a disaccharide sugar called lactulose.

Can Laxan be taken on an empty stomach?

Yes, Laxan can be taken on an empty stomach or at least 1 hour before or 2 hours after a meal.

Is there an appropriate storage temperature for Laxan?

Yes, Laxan should be stored at room temperature (15-30°C). It should not be refrigerated.

Is Laxan available over-the-counter?

Yes, Laxan is available over-the-counter in some countries. It is best to check with your local pharmacy or doctor for advice and availability.

Can I take Laxan before bed?

Yes, Laxan can be taken before bed. However, it is best to take it with a full glass of water as taking it with other liquids such as juice or coffee may interfere with its effectiveness.

Should I take Laxan with food?

It is not generally recommended to take Laxan with food as this may interfere with its effectiveness. It is best take it on an empty stomach or at least 1 hour before or 2 hours after a meal.

Can I take Laxan if I am allergic to milk or dairy products?

Yes, Laxan is suitable for people who are allergic to milk or dairy products, as it does not contain these ingredients.

Does Laxan have any interaction with other herbs and supplements?

Yes, Laxan may interact with other herbs and supplements. It is important to talk to your doctor or pharmacist before taking any other herbs or supplements while taking Laxan.

What if I take too much Laxan?

If you take too much Laxan, you may experience an increase in bloating, gas and loose stools. If you take more than your prescribed dose, seek medical attention immediately.

Should I take Laxan if I have Crohn's disease?

It is best to speak to your doctor before taking Laxan is you have Crohn's disease, as it may interact with other medications being taken. Your doctor may be able to recommend an alternative treatment.

What is the shelf life of Laxan?

The shelf life of Laxan is two years. It is important to make sure that you do not take Laxan beyond the expiration date.