Ketoford Plus
Ketoford Plus Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Ketoford Plus is a brand name. Its generic name is Beclometasone + Ketoconazole.
Introduction
Beclomethasone (BEC)/Ketoconazole (KCN) is a combination of two drugs which help to treat a variety of conditions including asthma, allergies, psoriasis and dermatologic infections. BEC is an inhaled corticosteroid which suppresses inflammation in the respiratory system while KCN is an antifungal which works to inhibit the growth of fungi and bacteria.Uses
Beclomethasone/Ketoconazole is used to treat severe asthma, allergies, and dermatologic infections. It is not used for the treatment of bacterial infections.Mechanism of Action
Beclomethasone/Ketoconazole helps to reduce inflammation and the overproduction of certain chemicals in the body that can cause an allergic reaction. BEC works to inhibit the release of inflammatory molecules, such as leukotrienes, while KCN helps to block the growth of fungi and bacteria.How Long Does it Take to Work?
Beclomethasone/Ketoconazole takes effect within minutes and generally begins to reduce symptoms within 24 hours.Absorption
Beclomethasone/Ketoconazole is rapidly absorbed into the bloodstream and reaches peak concentrations within 1 to 4 hours after administration.Route of Elimination
Beclomethasone/Ketoconazole is eliminated via urine and feces.Dosage
The recommended dose of Beclomethasone/Ketoconazole range from 80-320 mcg and 2-4 mg, respectively. The total daily dose should not exceed 320 mcg of Beclometasone and 8 mg of Ketoconazole.Administration
Beclomethasone/Ketoconazole is usually administered as an oral suspension or solution. It should be taken with food or milk.Side Effects
Common side effects of Beclomethasone/Ketoconazole include nausea, headache, anxiety, muscle pain, dizziness, diarrhea, weight gain and increased risk of infection.Toxicity
Beclomethasone/Ketoconazole may cause liver damage if taken at high doses or if taken for an extended period of time.Precautions
Patients taking Beclomethasone/Ketoconazole should avoid contact with persons with infectious diseases and should not receive live immunizations. Patients should also avoid exposure to extreme temperatures, alcohol and tobacco products.Interaction
Beclomethasone/Ketoconazole may interact with other medications, including antifungals, antibiotics, chemotherapeutics, diuretics, NSAIDs, salicylates, and sympathomimetics.Disease Interaction
Beclomethasone/Ketoconazole may cause or exacerbate certain medical conditions, including congestive heart failure, diabetes, glaucoma, hypertension, and osteoporosis.Drug Interaction
Beclomethasone/Ketoconazole may increase the effects or side effects of certain medications.Food Interactions
Beclomethasone/Ketoconazole should be taken with food or milk to increase its absorption.Pregnancy Use
Beclometasone/Ketoconazole should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.Lactation Use
Beclometasone/Ketoconazole is not recommended for use in nursing mothers as it may be excreted in breast milk.Acute Overdose
Acute overdose of Beclomethasone/Ketoconazole may cause fever, confusion, and vomiting. Seek medical attention if an overdose is suspected.Contraindications
Beclomethasone/Ketoconazole is contraindicated in patients with a known hypersensitivity to either component or any of the excipients.Dosage and Administration
Beclomethasone/Ketoconazole should be taken in the dosage and duration prescribed by the doctor. The maximum daily dose should not exceed 320 mcg of Beclometasone and 8 mg of Ketoconazole.Storage Condition
Beclomethasone/Ketoconazole should be stored away from light, heat and moisture.Volume of Distribution
The volume of distribution of Beclomethasone/Ketoconazole is approximately 8 L/kg.Half Life
The half-life of Beclomethasone/Ketoconazole is approximately 8 hours.Clearance
The clearance of Beclomethasone/Ketoconazole is approximately 1 L/kg/hr.Here you find in details version of Ketoford Plus