Tenebetic M
Tenebetic M Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Tenebetic M is a brand name. Its generic name is Metformin + Teneligliptin.
Introduction
Tenebetic M is an oral combination medication used to treat Type 2 diabetes. It helps to control blood glucose by reducing the production of glucose in the liver and increasing the uptake of glucose into the body's cells. It is approved for use in adults, but not approved in children or in pregnant women.
Uses for
Tenebetic M is used to treat adults with Type 2 diabetes. It is used when diet and exercise alone cannot control the blood glucose levels, and when the patient is not responding to other medications.
Mechanism of Action
Tenebetic M works by reducing the production of glucose in the liver and increasing the uptake of glucose into the body's cells. Metformin works by blocking an enzyme called gluconeogenesis which is responsible for the production of glucose in the liver. Teneligliptin works by increasing the release of a hormone called incretin which stimulates the beta cells in the pancreas to produce more insulin, leading to more efficient use of glucose in the body.
How Long Does It Take to Work?
Tenebetic M can take between 1 and 4 weeks to take effect. It may take longer to reach optimal blood glucose levels, depending on the individual.
Absorption
Tenebetic M is rapidly absorbed when taken orally, with peak concentrations occurring within 1-2 hours of dosing. Both components of the medication are absorbed in the small intestine.
Route of Elimination
Metformin or Teneligliptin are eliminated primarily through the kidneys, with peak concentrations occurring within 2-3 hours of dosing.
Dosage
The recommended dosage for Tenebetic M is one tablet twice daily. Each tablet contains 500 mg of metformin and 20 mg of teneligliptin.
Administration
Tenebetic M should be taken with food to reduce the risk of gastrointestinal side effects. It should be taken as prescribed and not be stopped or changed without speaking to a doctor first.
Side Effect
The most common side effects of Tenebetic M include nausea, vomiting, stomach pain, loss of appetite, diarrhea, headache, dizziness, drowsiness, and low blood sugar (hypoglycemia). Other possible side effects include allergic reactions, blurred vision, loss of appetite, and a decrease in red blood cell count (hematocrit).
Toxicity
Tenebetic M has a low toxicity level and is generally well tolerated by the body. The risks of overdose are rare, however, patients should seek medical help if they experience any symptoms of overdose, such as severe abdominal pain, nausea, vomiting, or confusion.
Precautions
Patients should inform their doctor of any medical conditions they have, including kidney or liver disease, diabetes, or anemia. Women who are pregnant or breast-feeding should not use Tenebetic M, as it could be unsafe for the developing fetus. Patients should not drink alcohol while taking this medication.
Interaction
Tenebetic M may interact with other medications such as probenecid, amiloride, rifampin, antibiotics, diuretics, anticoagulants, or aspirin. Patients should inform their doctor of any medications they are taking, both prescription and non-prescriptions, prior to taking Tenebetic M.
Disease Interaction
Tenebetic M can interact with certain diseases such as diabetes, kidney or liver disease, or anemia. Patients should inform their doctor of any health problems prior to taking Tenebetic M.
Drug Interaction
Tenebetic M may interact with other medications such as probenecid, amiloride, rifampin, antibiotics, diuretics, anticoagulants, steroids, or aspirin. Patients should inform their doctor of any medications they may be taking prior to taking Tenebetic M.
Food Interactions
Tenebetic M may interact with certain foods such as dairy products, high-fat, or high-sugar foods. Patients should limit their intake of these types of foods and beverages while taking this medication.
Pregnancy Use
Tenebetic M is not recommended for use in pregnant women, as it could cause harm to the developing baby. Women who are pregnant or plan to become pregnant should speak to their doctor before using this medication.
Lactation Use
Tenebetic M is not recommended for use while breastfeeding, as it can pass into breast milk and could cause harm to a nursing baby. Women who are breastfeeding should speak to their doctor before using this medication.
Acute Overdose
The signs and symptoms of an acute overdose of Tenebetic M include increasing drowsiness, rapid pulse, and vomiting. If a patient experiences any of these symptoms after taking this medication, they should seek medical help immediately.
Contraindication
Tenebetic M is contraindicated in patients with kidney impairment or chronic renal failure, as this medication can lead to lactic acidosis. It is also contraindicated in patients with severe dehydration, hypoxemia, or congestive heart failure.
Use Directions
Patients should take Tenebetic M as prescribed, with or without food. Patients should not stop or change their dose without speaking to their doctor first. Patients should inform their doctor of any side effects they may experience.
Storage Condition
Tenebetic M should be stored at room temperature away from moisture and heat. It should be kept out of children's reach.
Volume of Distribution
Tenebetic M is widely distributed in the body, with peak concentrations occurring in the liver, muscle, and fat tissue. The drug is not protein-bound in the body.
Half Life
The half-life of Tenebetic M is 3.5-4.9 hours. Peak concentrations of the drug in the body occur within 1-2 hours of dosing.
Clearance
The clearance of Tenebetic M is approximately 10-14 L/h. It is eliminated mainly through the kidneys, with peak concentrations occurring within 2-3 hours of dosing.
Here you find in details version of Tenebetic M
Some Frequently Asked Questions About Tenebetic M
.1. What is Tenebetic M?
Tenebetic M is a combination medicine used to treat type 2 diabetes mellitus (non-insulin-dependent diabetes). It contains two active ingredients, metformin and teneligliptin, which work in different ways to lower blood glucose levels in people with type 2 diabetes.
2. Who should not take Tenebetic M?
Tenebetic M is not suitable for everyone and certain health conditions may mean that this medicine is not suitable for you, including if you have: kidney or liver problems, moderate or severe kidney disease, or an allergy to metformin or teneligliptin.
3. What are the potential side effects of taking Tenebetic M?
Common side effects of taking Tenebetic M include nausea, diarrhoea, headache, abdominal pain, flatulence, and taste disturbances. If you experience any serious side effects, including a rash or swelling of the face, lips, or tongue, rapid weight gain, or difficulty breathing, you should seek medical attention.
4. What is the dosage of Tenebetic M?
The recommended dose of Tenebetic M is one tablet taken twice a day. It is important that you take the tablets at the same time each day, with meals or as per doctor's instruction. Follow your doctor’s instructions as to how much of the medication to take and how often. Do not increase or reduce the dose on your own.
5. What are the precautions to follow while taking Tenebetic M?
Before taking Tenebetic M, tell your doctor or pharmacist if you have any allergies, take any other medicines, have any severe kidney or liver problems, are pregnant, breastfeeding or planning to become pregnant.
6. Can I take Tenebetic M if I have kidney disease?
Tenebetic M should not be taken if you have moderate or severe kidney disease. You should talk to your doctor before taking this medicine if you have any degree of kidney impairment.
7. Can I drink alcohol while taking Tenebetic M?
Drinking alcohol can increase the risk of serious side effects of Tenebetic M, such as lactic acidosis. So it is best to avoid drinking alcohol while taking Tenebetic M.
8. Can I breastfeed while taking Tenebetic M?
Tenebetic M may pass into your breast milk, so it is not recommended to take this medicine while breastfeeding. You should talk to your doctor if you are breastfeeding before taking Tenebetic M.
9. Does Tenebetic M increase the risk of hypoglycaemia?
Tenebetic M may increase the risk of hypoglycaemia (low blood sugar levels). To help reduce this risk, it is important to monitor your blood sugar levels regularly and contact your doctor if they become too low.
10. Can I take Tenebetic M with other medicines?
You should talk to your doctor before taking Tenebetic M if you are taking other medicines, such as insulin, as these medicines may interact with each other. Your doctor may need to adjust your dose or monitor your treatment carefully if you are taking other medicines.
11. Is Tenebetic M effective in treating type 2 diabetes?
Tenebetic M is effective in treating type 2 diabetes, as it works in different ways to help lower blood glucose levels. However, it is important to remember that taking this medicine alone may not be enough to manage blood glucose levels, and that changes to diet and exercise will also be necessary for effective management of type 2 diabetes.
12. What should I do if I miss a dose of Tenebetic M?
If you miss a dose of Tenebetic M, take the missed dose as soon as you remember. However, if it is already almost time for your next dose, skip the missed dose and just take the next dose at the usual time.
13. Can Tenebetic M cause an increase in body weight?
Tenebetic M can cause an increase in body weight in some people. If you experience an increase in weight while taking this medicine, talk to your doctor to see if any changes to your treatment plan are required.
14. Can Tenebetic M cause jaundice?
Although rare, Tenebetic M may be associated with jaundice (yellowing of the skin or eyes). This is a potentially serious side effect and you should seek medical advice if you experience any signs or symptoms of jaundice.
15. Is there a generic version of Tenebetic M available?
No, there is no generic version of Tenebetic M available. However, some generic versions of Metformin and Teneligliptin may be available separately.
16. What should I do if I experience blurred vision while taking Tenebetic M?
If you experience blurred vision while taking Tenebetic M, contact your doctor as soon as possible, as this may be a sign of a serious side effect. Do not drive or operate heavy machinery until your vision is restored.
17. Is Tenebetic M suitable for people with type 1 diabetes?
No, Tenebetic M is not suitable for people with type 1 diabetes. This medicine is only indicated for the treatment of type 2 diabetes.
18. Is Tenebetic M safe in pregnancy?
Tenebetic M is not recommended for use in pregnancy, as it may pose a risk to the unborn child. You should talk to your doctor before taking this medicine if you are pregnant or planning to become pregnant.
19. What should I do if I forget to take Tenebetic M for a few days?
If you forget to take Tenebetic M for a few days, it is important to get back on track with your medication as soon as possible. Take the missed dose as soon as you remember, and contact your doctor for advice on managing your overall diabetes treatment.
20. Can Tenebetic M cause liver damage?
Tenebetic M may cause liver damage in some people. If you experience any symptoms of liver damage, such as yellowing of the skin or eyes, dark urine, or jaundice, contact your doctor immediately.
21. Can Tenebetic M cause dehydration?
Tenebetic M can cause dehydration in some people. You should stay well hydrated while taking this medicine, and contact your doctor if you experience any signs or symptoms of dehydration, such as dizziness, headache, severe thirst, decreased or increased urination, or dark urine.
22. What are the signs and symptoms of lactic acidosis?
The signs and symptoms of lactic acidosis include nausea and vomiting, abdominal pain, fatigue, rapid breathing, unusual muscle pain, unusual sleepiness or sleep disturbances, confusion, difficulty breathing, dizziness, or an irregular heartbeat.
23. What happens if I take an overdose of Tenebetic M?
If you take an overdose of Tenebetic M, contact your doctor or go to an emergency department immediately. An overdose can cause serious side effects, such as lactic acidosis or hypoglycaemia.
24. Can I take Tenebetic M with food?
Yes, it is recommended that you take Tenebetic M with food, as this can help to reduce stomach upset. You should take the medicine at the same time each day, usually twice a day, depending on what your doctor has prescribed.
25. Are there any drug interactions associated with Tenebetic M?
Yes, Tenebetic M may interact with other medications. Always tell your doctor and pharmacist about any other medications, vitamins, or herbal supplements you are taking. They can advise you on any potential interactions that may occur.
26. Is Tenebetic M safe for elderly people?
Tenebetic M is generally considered safe for elderly people, although certain health conditions may mean that this medicine is not suitable for them. Always tell your doctor if you have any health conditions before taking Tenebetic M.
27. Does Tenebetic M cause constipation?
Tenebetic M may cause constipation in some people. If you experience constipation while taking this medicine, contact your doctor or pharmacist for advice on how to manage this.
28. Is Tenebetic M available over the counter?
No, you will need a prescription from a doctor to purchase Tenebetic M. It is not available over the counter. You should talk to your doctor to see if this medication is suitable for you.
29. What should I tell my doctor before taking Tenebetic M?
Before taking Tenebetic M, tell your doctor if you have any allergies, any other medicines you are taking, have any kidney or liver problems, or are pregnant, breastfeeding or planning to become pregnant.
30. Can Tenebetic M cause stomach pain?
Tenebetic M may cause abdominal pain in some people. If you experience any stomach pain while taking this medicine, contact your doctor for advice.