Keplex

Keplex Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Keplex is a brand name. Its generic name is Cephalexin.

Introduction

Keplex is an antibiotic drug belonging to the cephalosporin class. It is used to treat bacterial infections caused by susceptible Gram-positive bacteria, including skin, respiratory, urinary tract, and bone infections. It is also often prescribed as an off-label remedy for UTI infections, acne, impetigo, and gum diseases.

Uses for

Keplex is primarily used in the treatment of infections caused by Gram-positive bacteria, such as streptococci and staphylococci. Some off-label uses for cephalexin include treatment of impetigo, gum diseases, and urinary tract infections.

Mechanism of Action

Keplex works by inhibiting the synthesis of peptidoglycan, which is an essential component of the bacterial cell wall. This action makes the cell wall weak and susceptible to destruction, leading to death of the bacterial cells.

How Long Does It Take To Work?

Keplex starts to work within 1 to 2 hours of taking the medicine. Symptoms of an infection should start to improve within a few days of taking the medication.

Absorption

Keplex is rapidly and completely absorbed following oral administration.

Route of Elimination

Keplex is eliminated through the kidneys by glomerular filtration and tubular secretion.

Dosage Information

Keplex is available in oral tablets and capsules in dosages of 250, 500, and 750 mg. For skin, bone, and urinary tract infections, the usual dose is 250-500mg twice daily or 500-750mg once daily. For respiratory infections, the usual dose is 250-500mg every 6-8 hours or 500-750mg every 12 hours.

Administration

Keplex should be taken with food and plenty of fluids to help prevent irritation of the stomach and intestines. If you miss a dose, take it as soon as you remember unless it is close to the time of your next dose. In that case, skip the missed dose and continue with your regular dosing schedule.

Side Effects

Common side effects of Keplex include nausea, vomiting, and diarrhea. Other side effects include rash, dizziness, headache, and abdominal pain. In rare cases, Keplex may also cause allergic reactions or liver damage. Call your doctor right away if you experience any unusual or severe symptoms.

Toxicity

Keplex is considered to be safe and well-tolerated. However, an overdose may lead to nausea, vomiting, and diarrhea. Severe overdose may result in liver damage, kidney damage, and coma.

Precaution

Patients with kidney and/or liver disease, asthma, and pregnant or breastfeeding women should take Keplex with caution, as they are more susceptible to its side effects. As the drug may interact with other medications, it is important to inform your physician if you are on any other medication, including over the counter drugs.

Interaction

Keplex may interact with other drugs and should not be administered with drugs that reduce the activity of bacteria, such as tetracyclines and macrolide antibiotics.

Disease Interaction

Keplex may interact with certain chronic diseases, such as kidney and liver disease. Patients with kidney or liver disease should take the medication with caution and under medical supervision.

Drug Interaction

Keplex may interact with other drugs, such as penicillin, tetracyclines, and macrolide antibiotics. It may also interact with drugs that reduce the activity of bacteria, such as chloramphenicol, probenecid, and allopurinol. It is important to inform your physician if you are taking any other medication before taking cephalexin.

Food Interactions

Keplex may interact with food and beverages. Taking it with food may decrease its effectiveness. It should not be taken with alcohol.

Pregnancy Use

Pregnant women should take cephalexin with caution and only after consulting their physician. This drug can be used during pregnancy if deemed necessary by the physician.

Lactation Use

Keplex should be used with caution in lactating women. It should not be used during the first trimester of pregnancy.

Acute Overdose

An overdose of cephalexin may lead to nausea, vomiting, and diarrhea. Severe overdoses may cause liver damage, kidney damage, and even coma in rare cases. Seek medical attention right away if you suspect an overdose.

Contraindication

Keplex should not be used in patients with known hypersensitivity or allergy to cephalosporins. It should also not be used in patients with kidney and liver disease.

Use Direction

Keplex should be used as directed by a physician. Take it with food and plenty of fluids to help prevent stomach irritation. Do not skip doses or stop taking the drug even if symptoms improve.

Storage Condition

Keplex should be stored at room temperature, away from heat and moisture. Keep all medicines out of reach of children.

Volume of Distribution

Keplex has a volume of distribution of 0.14-0.25 L/kg.

Half Life

The half life of cephalexin is 0.9-1.2 hours.

Clearance

The clearance of cephalexin is 0.07-0.55 L/h/kg.

Here you find in details version of Keplex

Some Frequently Asked Questions About Keplex

What is Keplex?

Keplex is a type of medication known as a cephalosporin antibiotic. It is used to treat certain types of bacteria infections.

What are the uses of Keplex?

Keplex is used to treat a wide range of bacterial infections in the body. These include infections of the skin, respiratory tract, urinary tract, ears, and bones. It can also be used to prevent or treat certain bacterial infections in the lungs.

What is the usual dosage of Keplex?

The usual dosage of Keplex is 250 mg every 6-8 hours for adults. The dosage may vary based on age, weight, and condition of the patient.

What are the side effects of Keplex?

The most common side effects of Keplex include nausea, vomiting, diarrhea, headache, and rash. More serious side effects include abdominal pain, difficulty breathing, dizziness, and seizures.

Is Keplex safe for pregnant women?

Keplex is safe for pregnant women when taken as directed by your doctor. It is important to tell your doctor if you are pregnant before taking this medication.

Can Keplex be used to treat a sinus infection?

Yes, Keplex can be used to treat a sinus infection. It works by killing the bacteria that cause the infection.

What should I do if I miss a dose of Keplex?

If you miss a dose of Keplex, take it as soon as you remember. If it is close to your next dose, skip the missed dose and continue with your regular schedule.

Is Keplex effective against strep throat?

Yes, Keplex is effective against strep throat. It can be used to treat strep throat, as well as other bacterial infections.

What should be avoided while taking Keplex?

You should avoid alcohol while taking Keplex as it can increase the risk of side effects. You should also avoid taking other medications that can interact with Keplex such as antacids or probenecid.

Should I take Keplex with food?

You may take Keplex with food or on an empty stomach. However, taking it with food may help to reduce the risk of side effects.

Does Keplex interact with any other medications?

Yes, Keplex can interact with other medications, including some antibiotics. It is important to tell your doctor about any other medications you are taking before taking Keplex.

What other forms does Keplex come in?

Keplex is available as tablets, capsules, suspension, and as an injection. It is important to follow your doctor's instructions for taking the medication.

Is Keplex safe for children?

Yes, Keplex is safe for children when taken as directed. Your doctor will adjust the dosage depending on your child's age, weight, and medical condition.

What is the shelf life of Keplex?

The shelf life of Keplex depends on the specific formulation and dosage form. Generally, tablets, capsules, and suspension have a shelf life of 3-5 years.

Is Keplex a penicillin?

No, Keplex is not a penicillin. It belongs to a group of medications called cephalosporin antibiotics.

Is Keplex safe for people with kidney problems?

Yes, Keplex is safe for people with kidney problems when taken as prescribed by your doctor. Your doctor may adjust the dosage depending on your condition.

Is Keplex an over-the-counter medication?

No, Keplex is not an over-the-counter medication and must be prescribed by your doctor.

Can Keplex be used to treat urinary tract infections?

Yes, Keplex can be used to treat urinary tract infections. It works by killing the bacteria that cause the infection.

Can Keplex treat a tooth infection?

Yes, Keplex can be used to treat a tooth infection. However, it is important to consult your doctor or dentist for the correct diagnosis and treatment.

Do I need to finish the full course of Keplex?

Yes, it is important to finish the full course of Keplex as prescribed by your doctor. This will help to ensure that your infection is fully treated and will help to prevent any resistance to the medication.

Can I take Keplex while I am breastfeeding?

Yes, Keplex is safe to take while breastfeeding. However, you should tell your doctor if you are breastfeeding before taking this medication.

Is Keplex effective against viral infections?

No, Keplex is not effective against viral infections as it is an antibiotic, which only works on bacterial infections.

Can Keplex treat a strep throat?

Yes, Keplex can be used to treat strep throat and other bacterial infections.

Should I avoid any food while taking Keplex?

You should avoid eating dairy products such as milk, cheese, or yogurt while taking Keplex as they can reduce the effectiveness of the medication.

Can Keplex be used to treat a bacterial sinus infection?

Yes, Keplex can be used to treat a bacterial sinus infection. It works by killing the bacteria that cause the infection.

Can Keplex treat a chest infection?

Yes, Keplex can be used to treat a chest infection. You should see your doctor if the infection persists for more than five days or if it worsens.

Can Keplex cause an allergic reaction?

Yes, Keplex can cause an allergic reaction in some people. Symptoms of an allergic reaction include itching, rash, difficulty breathing, and swelling of the face, lips, or tongue.

Can Keplex be taken on an empty stomach?

Yes, Keplex can be taken on an empty stomach. However, taking it with food may help to reduce the risk of side effects.

Can Keplex cause diarrhea?

Yes, Keplex can cause diarrhea in some people. It is important to drink plenty of fluids while taking this medication to help prevent dehydration.

What is the recommended dose of Keplex for adults?

The recommended dose of Keplex for adults is 250 mg every 6-8 hours. Your doctor may adjust the dose depending on your age, weight, and medical condition.

Can Keplex cause yeast infections?

Yes, Keplex can cause yeast infections in some people. It is important to tell your doctor if you experience any signs of a yeast infection such as itching, burning, or white patches.

How long does it take for Keplex to work?

Keplex usually starts to work within one to two hours of taking the medication. Results can vary based on the type of infection and person's individual response to the medication.

How long should I take Keplex for?

You should take Keplex for as long as your doctor recommends. This may be different for each person and will depend on the type of infection being treated.

Is Keplex available in generic form?

Yes, Keplex is available in generic form. Generic medications have the same active ingredient as the brand name and are usually more affordable.

What are the most common side effects of Keplex?

The most common side effects of Keplex include nausea, vomiting, diarrhea, headache, and rash. More serious side effects include abdominal pain, difficulty breathing, dizziness, and seizures.

Can Keplex be used to treat a urinary tract infection?

Yes, Keplex can be used to treat a urinary tract infection. It works by killing the bacteria that cause the infection.

Are there any foods I should avoid while taking Keplex?

You should avoid eating dairy products such as milk, cheese, or yogurt while taking Keplex as they can reduce the effectiveness of the medication.

What are the signs of an allergic reaction to Keplex?

The signs of an allergic reaction to Keplex include itching, rash, difficulty breathing, and swelling of the face, lips, or tongue.

Can Keplex be used to treat a bladder infection?

Yes, Keplex can be used to treat a bladder infection. It works by killing the bacteria that cause the infection.

Can Keplex cause nausea?

Yes, Keplex can cause nausea in some people. It is important to drink plenty of fluids while taking this medication to help prevent dehydration.

Is Keplex safe for elderly patients?

Yes, Keplex is safe for elderly patients when taken as prescribed by your doctor. Your doctor may adjust the dosage depending on your age and medical condition.

Can Keplex be used to treat strep throat?

Yes, Keplex can be used to treat strep throat and other bacterial infections.

Can Keplex be used to treat a skin infection?

Yes, Keplex can be used to treat a skin infection. It works by killing the bacteria that cause the infection.