Ivabratco
Ivabratco Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Ivabratco is a brand name. Its generic name is Ivabradine.
Ivabratco Introduction and Uses
Ivabratco is an antiarrhythmic drug used in the treatment of symptomatic stable angina, specifically in those patients having hypertension and a resting heart rate of 75 beats per minute or greater. It is a selective if inhibitor – acting on the If current in the sinoatrial node of the heart. Its primary effect is to reduce heart rate, and in doing so, reduce the oxygen demand on the myocardium by up to 10–15%.
Mechanism of Action
Ivabratco acts by selectively inhibiting the If current within the sinoatrial node, a specialized group of cells in the heart responsible for setting the pace of the heartbeat. The If current determines the slow-inward diastolic depolarization of the cells, meaning it determines how often the cells depolarize. By inhibiting the If current, the heart rate is decreased which reduces the oxygen demand of the myocardium.
How Long Does It Take to Work?
The effects of ivabradine can be seen within two hours of ingestion and its effect on heart rate is usually seen within two days. It is recommended to take the medication on an empty stomach to achieve the fullest effect.
Absorption
Ivabratco is rapidly absorbed from the gut but its rate of absorption is not affected by food intake. After maximal absorption, the concentration of ivabradine in the circulation increases slowly and reaches its peak concentration after four to six hours.
Route of Elimination
Ivabratco is primarily eliminated through biliary excretion. Following a single dose of ivabradine, approximately 68% of the dose was eliminated in the bile. The remainder of the dose is excreted in the urine and feces.
Dosage
Ivabratco is available as oral tablets with doses ranging from 2.5 mg to 15 mg. The usual recommended dose for the treatment of stable angina is 7.5 mg once daily taken on an empty stomach. The dose can be titrated up to a maximum of 15 mg once daily if necessary.
Administration
Ivabratco should be taken with a full glass of water and should be taken on an empty stomach, i.e. at least two hours after eating or two hours before eating, for maximum effect. To reduce the risk of dizziness, it is important to take this medication exactly as prescribed.
Side Effects
The most common side effects of ivabradine include dizziness, headache, nausea, bradycardia, fatigue, diarrhea, abdominal pain and dyspepsia. Patients should seek medical attention if these side effects persist or become worse. Rarely, serious side effects such as swelling, breathing difficulty and palpitations may occur.
Toxicity
The toxicity of ivabradine has not been established. There have been no reported cases of overdose with this drug. In the event of an overdose, symptomatic treatment is recommended.
Precautions
Patients with certain medical conditions should not take ivabradine, including those with severe bradycardia, severe hypotension, moderate to severe renal impairment, or heart failure of NYHA class III or IV. In addition, patients taking certain medications such as calcium channel blockers, vasodilators, beta-blockers, and certain antibiotics should not take ivabradine.
Interaction
Ivabratco can interact with certain drugs, including calcium channel blockers, vasodilators such as nitroglycerin, certain antibiotics, beta-blockers, and digoxin. The combination of these drugs could cause an excessive bradycardia and hypotension. Close medical monitoring is recommended for patients taking these medications.
Disease Interaction
Patients with certain diseases should not take ivabradine, including those with severe bradycardia, severe hypotension, moderate to severe renal impairment, or heart failure of NYHA class III or IV. Certain medications, such as calcium channel blockers, vasodilators, beta-blockers, and certain antibiotics, can also interact with ivabradine and should be avoided in these patients.
Drug Interaction
Certain drugs, including calcium channel blockers, vasodilators, beta-blockers, and certain antibiotics, can interact with ivabradine and should be avoided. Ivabratco should not be used concomitantly with other If current inhibitors due to the risk of additive bradycardic effect.
Food Interactions
The rate of absorption of ivabradine is not affected by food intake, but it is recommended to take on an empty stomach for maximum effect.
Pregnancy Use
Ivabratco has not been studied in pregnant women and its use is not recommended. Animal studies have shown some evidence of fetotoxicity but a risk to humans has not been established.
Lactation Use
Ivabratco has not been studied in women who are breastfeeding and its use is not recommended.
Acute Overdose
There are no known reports of an overdose of ivabradine and its toxicity has not been established. Symptomatic treatment should be initiated if an overdose is suspected.
Contraindication
Ivabratco is contraindicated in patients with severe bradycardia, severe hypotension, moderate to severe renal impairment, or heart failure of NYHA class III or IV, as well as in patients taking certain medications such as calcium channel blockers, vasodilators, beta-blockers, and certain antibiotics.
Use Direction
Ivabratco should be taken with a full glass of water and should be taken on an empty stomach, i.e. at least two hours after eating or two hours before eating, for maximum effect. The dose should be reduced in patients with renal impairment. The dose should be gradually reduced and/or discontinued in patients with a reduction in heart rate or increase in blood pressure.
Storage Condition
Ivabratco should be stored between 4 C and 25 C. It should be kept away from direct moisture, humidity, and light.
Volume of Distribution
The volume of distribution of ivabradine is 11 liters.
Half Life
The elimination half-life of ivabradine is 6 hours.
Clearance
The clearance of ivabradine is 5.9 liters/hour.
Here you find in details version of Ivabratco
Some Frequently Asked Questions About Ivabratco
What is Ivabratco?
Ivabratco is a prescription medication used to treat chronic stable angina (chest pain) associated with chronic coronary artery disease. It works by reducing the heart rate to improve blood flow to the heart and reduce symptoms of angina.
What is Ivabratco used for?
Ivabratco is used to treat chronic stable angina (chest pain) associated with chronic coronary artery disease. It works by reducing the heart rate to improve blood flow to the heart and reduce symptoms of angina.
Who is Ivabratco for?
Ivabratco is for adults with chronic stable angina pectoris (chest pain) associated with chronic coronary artery disease. It may not be appropriate for those with certain medical conditions, so it’s important to talk to your doctor before taking it.
How does Ivabratco work?
Ivabratco works by reducing the heart rate. It blocks some of the nerve signals that tell your heart to beat faster and harder, reducing the amount of work your heart has to do. This helps to reduce symptoms of angina and improve blood flow to the heart.
What are the side effects of Ivabratco?
The most common side effects of Ivabratco include headache, nausea, dizziness, tiredness, and diarrhea. Other possible side effects include flushing, rash, and palpitations. If any of these side effects become persistent or bothersome, speak to your doctor.
Is Ivabratco safe?
Yes, Ivabratco is generally safe when taken as prescribed. However, like all medications, it may not be right for everyone. It’s important to talk to your doctor before taking Ivabratco to make sure it is safe for you.
What is the dosage of Ivabratco?
The recommended starting dose for Ivabratco is 5 mg twice daily, taken with or without food. Your dose should be adjusted to a maximum of 7.5 mg twice daily depending on how you respond to the medication and any side effects you may experience.
Can I take other medications with Ivabratco?
Yes, you can take other medications with Ivabratco, but it’s important to talk to your doctor before combining it with any other medications. Certain medications may interfere with the way Ivabratco works or increase your risk of side effects.
What should I do if I miss a dose of Ivabratco?
If you miss a dose of Ivabratco, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the next dose at the regular time. Do not take a double dose of Ivabratco to make up for a missed dose.
Is Ivabratco available over the counter?
No, Ivabratco is not available over the counter. It is a prescription medication that must be prescribed by a doctor.
Should I take Ivabratco with food?
Ivabratco can be taken with or without food. However, it may be best to take it with food to reduce the risk of nausea.
What are the warnings and precautions associated with Ivabratco?
Ivabratco should not be used if you are pregnant or breastfeeding. It is also important to tell your doctor if you have any other medical conditions or allergies, and if you are taking any other medications, supplements, or herbal remedies.
Can I drink alcohol with Ivabratco?
It is not recommended to drink alcohol while taking Ivabratco as it can increase the risk of certain side effects. If you choose to drink alcohol while taking Ivabratco, it is important to do so in moderation.
Can I drive or operate machinery while taking Ivabratco?
Ivabratco can cause drowsiness and dizziness. It is best to avoid driving or operating machinery until you know how Ivabratco affects you.
How long does Ivabratco take to work?
It may take several weeks for Ivabratco to have its full effect. Talk to your doctor if you do not notice any improvements in your symptoms after taking the medication for a few weeks.
What are the storage requirements for Ivabratco
Ivabratco should be stored at room temperature between 59 to 86 degrees Fahrenheit (15 to 30 degrees Celsius). Keep it in a closed, airtight container, away from heat, moisture, and direct sunlight.
Can Ivabratco be crushed or split?
Do not crush or split the Ivabratco tablets. Swallow them whole with a glass of water. Talk to your doctor or pharmacist if you have any difficulty swallowing the medication.
What is the cost of Ivabratco?
The cost of Ivabratco varies depending on where it is purchased. It may be covered by your insurance or may require a co-pay. Talk to your doctor or pharmacist about any questions you may have about the cost of Ivabratco.
How should Ivabratco be stored?
Ivabratco should be stored at room temperature between 59 to 86 degrees Fahrenheit (15 to 30 degrees Celsius). Keep it in a closed, airtight container, away from heat, moisture, and direct sunlight.
Are there any interactions with Ivabratco and other medications?
Yes. Ivabratco may interact with certain medications, including beta-blockers, calcium channel blockers, and digoxin. It is important to talk to your doctor before taking any new medications while taking Ivabratco.
What are the signs of an allergic reaction to Ivabratco?
Signs of an allergic reaction to Ivabratco may include hives, difficulty breathing, rash, itching, swelling of the face, throat, tongue, or lips, or wheezing. If you experience any of these symptoms, stop taking Ivabratco and seek medical attention immediately.
Does Ivabratco lower blood pressure?
No, Ivabratco does not lower blood pressure. It is used to treat chronic stable angina (chest pain) associated with chronic coronary artery disease by reducing the heart rate.
Is Ivabratco safe for long-term use?
Ivabratco is generally safe for long-term use when taken as prescribed. However, it is important to talk to your doctor if you plan to take the medication for a long period of time.
Does Ivabratco cause weight gain?
No, Ivabratco does not cause weight gain. However, some people may gain weight while taking Ivabratco due to other side effects, such as fatigue and dizziness, which can lead to overeating.
Does Ivabratco cause erectile dysfunction?
No, there is no evidence that suggests Ivabratco causes erectile dysfunction. However, some men may experience decreased sexual desire or difficulty getting an erection while taking Ivabratco. If this occurs, talk to your doctor.
Does Ivabratco affect blood sugar levels?
No, Ivabratco does not affect blood sugar levels. However, some people with diabetes may experience changes in blood sugar levels while taking Ivabratco. It’s important to monitor your blood sugar levels closely while taking Ivabratco.
Can I take Ivabratco while breastfeeding?
No, Ivabratco should not be taken while breastfeeding. If you are breastfeeding, talk to your doctor before taking Ivabratco to discuss whether it is safe for you.
Is Ivabratco effective in treating angina?
Yes, Ivabratco is effective in treating angina (chest pain) associated with chronic coronary artery disease. It works by reducing the heart rate to improve blood flow to the heart and reduce symptoms of angina.
Can I take a pain reliever while taking Ivabratco?
Yes, it is generally safe to take a pain reliever such as ibuprofen or acetaminophen while taking Ivabratco. However, it’s important to talk to your doctor before taking any new medications while taking Ivabratco.
Does Ivabratco cause insomnia?
No, there is no evidence that Ivabratco causes insomnia. However, some people may experience insomnia or other sleep disturbances while taking Ivabratco. If this occurs, talk to your doctor.
Does Ivabratco cause constipation?
No, there is no evidence that Ivabratco causes constipation. However, some people may experience constipation or other gastrointestinal side effects while taking Ivabratco. If this occurs, talk to your doctor.
Does Ivabratco interact with alcohol?
Yes, it is not recommended to drink alcohol while taking Ivabratco as it can increase the risk of certain side effects. If you choose to drink alcohol while taking Ivabratco, it is important to do so in moderation.
What should I do if I experience side effects from taking Ivabratco?
If you experience any bothersome or persistent side effects while taking Ivabratco, talk to your doctor. Your doctor may adjust your dose or offer other treatments to help reduce your symptoms.
Can I take Ivabratco during pregnancy?
No, Ivabratco should not be used during pregnancy as it may cause harm to the fetus. Talk to your doctor if you are pregnant or planning to become pregnant before taking Ivabratco.
Does Ivabratco have any long-term effects?
No serious long-term effects have been reported with the use of Ivabratco. However, it is important to talk to your doctor before taking the medication for a long period of time.
How often should I take Ivabratco?
Ivabratco should be taken twice daily, with or without food. Your doctor will determine the right dosage for you based on your individual needs.
Is Ivabratco a blood thinner?
No, Ivabratco is not a blood thinner. It is used to treat chronic stable angina (chest pain) associated with chronic coronary artery disease by reducing the heart rate.
Does Ivabratco cause fatigue?
Yes, fatigue is a common side effect of Ivabratco. If you experience fatigue while taking Ivabratco, talk to your doctor as your dose may need to be adjusted.
Does Ivabratco cause hair loss?
No, there is no evidence that Ivabratco causes hair loss. If you experience any unusual hair loss, talk to your doctor.
Does Ivabratco cause dizziness?
Yes, dizziness is a common side effect of Ivabratco. If you experience dizziness while taking Ivabratco, talk to your doctor as your dose may need to be adjusted.
Can Ivabratco be taken with other heart medications?
Yes, Ivabratco can be taken with other heart medications, such as beta-blockers, calcium channel blockers, and digoxin. It is important to talk to your doctor before combining any medications.
Does Ivabratco cause headaches?
Yes, headache is a common side effect of Ivabratco. If you experience headaches while taking Ivabratco, talk to your doctor as your dose may need to be adjusted.