Ilopride
Ilopride Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Ilopride is a brand name. Its generic name is Iloperidone.
etcIlopride Introduction
Ilopride is a medication used to treat schizophrenia. It is an atypical antipsychotic drug that was approved by the U.S. Food and Drug Administration in 2009. It is believed to act on certain dopamine and serotonin receptors within the brain. Ilopride works by changing the activity of certain chemicals in the brain, which helps to improve symptoms such as confusion, delusions, and hallucinations.
Uses for Ilopride
Ilopride is used to treat symptoms of schizophrenia. It may also be used in combination with other medications to treat bipolar disorder.
Mechanism of Action
Ilopride is believed to act on several dopamine and serotonin receptors within the brain. By blocking the activity of these receptors, Ilopride may reduce symptoms of schizophrenia, such as delusions, hallucinations, and confusion. Ilopride may also reduce symptoms of bipolar disorder.
How Long Does It Take to Work?
It takes approximately 4 to 6 weeks for Ilopride to become fully effective. It is important to stay on the prescribed dosage and not to stop taking Ilopride suddenly.
Absorption
Ilopride is absorbed in the intestines and metabolized in the liver before entering the bloodstream. On average, it takes about 6 hours for the medication to reach maximum effectiveness.
Route of Elimination
Ilopride is eliminated through the kidneys. Its metabolites are excreted in the urine.
Dosage
The recommended dosage of Ilopride depends on the individual’s age, response to therapy, and other medications or supplements taken. Generally, iloperidone is started at a dosage of 1 to 2 mg taken twice daily. The total daily dosage should not exceed 12 mg. Dosages can be increased in increments of 2 mg at intervals of three to four days.
Administration
Ilopride should be taken orally with food and water. It may be taken with or without meals. It is important to take the medication at the same time each day.
Side Effects
Common side effects of Ilopride include weight gain, dry mouth, dizziness, headache, constipation, and drowsiness. These side effects usually resolve over time and are usually not severe. Other more serious side effects include changes in vision, muscle spasms, trouble breathing, chest pain, increased heart rate, and symptoms of low blood pressure (dizziness, lightheadedness, fainting).
Toxicity
Overdose of Ilopride can cause severe symptoms, including dangerously low blood pressure, irregular heart rhythm, difficulty breathing, coma, and even death. If overdose is suspected, call the Poison Help line at 1-800-222-1222.
Precaution
Before taking Ilopride, it is important to inform your doctor about all other medications that you are taking.Ilopride may interact with other medications and may increase the risk of cardiovascular problems.Patients with heart, liver, or kidney problems should take special caution while taking Ilopride.
Interaction
It is important to inform your doctor about all medications, supplements, and vitamins that you are taking, as well as any health problems. Ilopride may interact with other drugs and can increase the risk of cardiovascular problems.
Disease Interaction
Ilopride can interact with a variety of conditions and diseases. These include liver and kidney disease, diabetes, seizures, high or low blood pressure, and conditions that predispose to dangerous changes in heartbeat, such as heart attack, stroke, and a disorder of the electrical system of the heart known as long QT interval. It is important to inform your doctor of all medical conditions before taking Ilopride.
Drug Interaction
Ilopride may interact with other drugs, including blood thinners, seizure medications, antibiotics, and certain antidepressants. It may also interact with drugs such as warfarin, quinidine, and carbamazepine. Patients taking any of these medications should inform their doctor before taking Ilopride.
Food Interactions
It is generally safe to take Ilopride with food, but it may interact with food containing tyramine. Tyramine is found in aged cheeses, smoked fish, certain wines, and certain beers. Eating food with tyramine while taking Ilopride can increase your risk of high blood pressure. It is important to talk to your doctor before taking Ilopride with food containing tyramine.
Pregnancy Use
Ilopride may be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Patients should inform their doctor if they are pregnant or plan to become pregnant before taking Ilopride.
Lactation Use
It is not known if Ilopride is present in breast milk. Patients should inform their doctor if they are breastfeeding before taking Ilopride.
Acute Overdose
Symptoms of acute overdose with Ilopride include dizziness, drowsiness, blurred vision, confusion, rapid heartbeat, muscle spasms, agitation, and difficulty speaking. Patients experiencing an acute overdose of Ilopride should seek immediate medical attention.
Contraindication
People with a known hypersensitivity to Ilopride or any of its components should not take this medication. Ilopride may also interact with other drugs and can cause dangerous changes in heartbeat, so patients should inform their doctor of all medications and supplements that they are taking before taking Ilopride.
Use Direction
Ilopride should be taken orally with food and water. It may be taken with or without meals. It is important to take the medication at the same time each day and not to stop taking it suddenly.
Storage Condition
Ilopride should be stored in a cool, dry place away from direct sunlight and away from children and pets. Do not store in the bathroom or near any sources of moisture or heat.
Volume of Distribution
The volume of distribution of Ilopride is 2.3 to 3.1 L/kg.
Half Life
The half life of Ilopride is 8 to 17.5 hours.
Clearance
The average clearance of Ilopride is 17.3 L/hr.
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