Iloperidona

Iloperidona Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Iloperidona is a brand name. Its generic name is Iloperidone.

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Iloperidona Introduction

Iloperidona is a medication used to treat schizophrenia. It is an atypical antipsychotic drug that was approved by the U.S. Food and Drug Administration in 2009. It is believed to act on certain dopamine and serotonin receptors within the brain. Iloperidona works by changing the activity of certain chemicals in the brain, which helps to improve symptoms such as confusion, delusions, and hallucinations.

Uses for Iloperidona

Iloperidona is used to treat symptoms of schizophrenia. It may also be used in combination with other medications to treat bipolar disorder.

Mechanism of Action

Iloperidona is believed to act on several dopamine and serotonin receptors within the brain. By blocking the activity of these receptors, Iloperidona may reduce symptoms of schizophrenia, such as delusions, hallucinations, and confusion. Iloperidona may also reduce symptoms of bipolar disorder.

How Long Does It Take to Work?

It takes approximately 4 to 6 weeks for Iloperidona to become fully effective. It is important to stay on the prescribed dosage and not to stop taking Iloperidona suddenly.

Absorption

Iloperidona is absorbed in the intestines and metabolized in the liver before entering the bloodstream. On average, it takes about 6 hours for the medication to reach maximum effectiveness.

Route of Elimination

Iloperidona is eliminated through the kidneys. Its metabolites are excreted in the urine.

Dosage

The recommended dosage of Iloperidona depends on the individual’s age, response to therapy, and other medications or supplements taken. Generally, iloperidone is started at a dosage of 1 to 2 mg taken twice daily. The total daily dosage should not exceed 12 mg. Dosages can be increased in increments of 2 mg at intervals of three to four days.

Administration

Iloperidona should be taken orally with food and water. It may be taken with or without meals. It is important to take the medication at the same time each day.

Side Effects

Common side effects of Iloperidona include weight gain, dry mouth, dizziness, headache, constipation, and drowsiness. These side effects usually resolve over time and are usually not severe. Other more serious side effects include changes in vision, muscle spasms, trouble breathing, chest pain, increased heart rate, and symptoms of low blood pressure (dizziness, lightheadedness, fainting).

Toxicity

Overdose of Iloperidona can cause severe symptoms, including dangerously low blood pressure, irregular heart rhythm, difficulty breathing, coma, and even death. If overdose is suspected, call the Poison Help line at 1-800-222-1222.

Precaution

Before taking Iloperidona, it is important to inform your doctor about all other medications that you are taking.Iloperidona may interact with other medications and may increase the risk of cardiovascular problems.Patients with heart, liver, or kidney problems should take special caution while taking Iloperidona.

Interaction

It is important to inform your doctor about all medications, supplements, and vitamins that you are taking, as well as any health problems. Iloperidona may interact with other drugs and can increase the risk of cardiovascular problems.

Disease Interaction

Iloperidona can interact with a variety of conditions and diseases. These include liver and kidney disease, diabetes, seizures, high or low blood pressure, and conditions that predispose to dangerous changes in heartbeat, such as heart attack, stroke, and a disorder of the electrical system of the heart known as long QT interval. It is important to inform your doctor of all medical conditions before taking Iloperidona.

Drug Interaction

Iloperidona may interact with other drugs, including blood thinners, seizure medications, antibiotics, and certain antidepressants. It may also interact with drugs such as warfarin, quinidine, and carbamazepine. Patients taking any of these medications should inform their doctor before taking Iloperidona.

Food Interactions

It is generally safe to take Iloperidona with food, but it may interact with food containing tyramine. Tyramine is found in aged cheeses, smoked fish, certain wines, and certain beers. Eating food with tyramine while taking Iloperidona can increase your risk of high blood pressure. It is important to talk to your doctor before taking Iloperidona with food containing tyramine.

Pregnancy Use

Iloperidona may be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Patients should inform their doctor if they are pregnant or plan to become pregnant before taking Iloperidona.

Lactation Use

It is not known if Iloperidona is present in breast milk. Patients should inform their doctor if they are breastfeeding before taking Iloperidona.

Acute Overdose

Symptoms of acute overdose with Iloperidona include dizziness, drowsiness, blurred vision, confusion, rapid heartbeat, muscle spasms, agitation, and difficulty speaking. Patients experiencing an acute overdose of Iloperidona should seek immediate medical attention.

Contraindication

People with a known hypersensitivity to Iloperidona or any of its components should not take this medication. Iloperidona may also interact with other drugs and can cause dangerous changes in heartbeat, so patients should inform their doctor of all medications and supplements that they are taking before taking Iloperidona.

Use Direction

Iloperidona should be taken orally with food and water. It may be taken with or without meals. It is important to take the medication at the same time each day and not to stop taking it suddenly.

Storage Condition

Iloperidona should be stored in a cool, dry place away from direct sunlight and away from children and pets. Do not store in the bathroom or near any sources of moisture or heat.

Volume of Distribution

The volume of distribution of Iloperidona is 2.3 to 3.1 L/kg.

Half Life

The half life of Iloperidona is 8 to 17.5 hours.

Clearance

The average clearance of Iloperidona is 17.3 L/hr.

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