Hidine

Hidine Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Hidine is a brand name. Its generic name is Olopatadine.

Introduction

Hidine (also known by its brand name, Patanol) is a medication used to treat allergic conjunctivitis, a type of eye inflammation caused by allergies. It is a topical antihistamine and mast cell stabilizer combination which works to reduce the release of allergy-causing substances from cells. It acts to alleviate symptoms like itching, tearing, and swelling of the eyes.

Uses and Mechanism of Action

Hidine is used to treat itchy, watery, red eyes that are caused by allergic conjunctivitis. It works by blocking the release of inflammatory substances from mast cells of the conjunctiva. It also blocks the action of histamine, a substance which plays a key role in the development of allergic inflammation.

How Long Does it Take to Work?

Hidine is usually effective within 30 minutes to 4 hours after administration. It is recommended to follow the instructions of your doctor when using the medication.

Absorption

Hidine is rapidly absorbed after topical administration and has an absolute bioavailability of 30%.

Route of Elimination

Hidine is eliminated through the feces and urine, primarily by metabolism and urinary excretion.

Dosage

The recommended dosage of Hidine is 1 or 2 drops in each affected eye times daily. The dosage may vary depending on the age of the person, severity of symptoms, and response to treatment.

Administration

Hidine should be administered to the affected eye(s). It is important to shake the bottle before using. The tip of the bottle should be touched with the fingertip and not the eye's inner surfaces. The bottle should not be used to touch the eye(s) and should be replaced if it becomes contaminated.

Side Effects

Common side effects associated with the use of Hidine include dry eyes, burning or stinging in the eyes, blurry vision, increased sensitivity to light, and temporary blurred vision. Other serious side effects that require immediate medical attention include chest tightness, wheezing, difficulty breathing, swelling of the face, lips, or tongue, and eye pain.

Toxicity

Hidine is usually well tolerated. However, an overdose can lead to side effects such as irritation and blurred vision. In case of an overdose, seek medical attention right away.

Precautions and Contraindications

Before using Hidine, inform your doctor of any allergies, chronic illnesses, current medications, or pre-existing conditions. It should not be used in individuals with glaucoma, untreated angle-closure glaucoma, or in individuals with known hypersensitivity to any of its components. It should also not be used in children younger than 3 years of age.

Interactions

Hidine should not be used in combination with other eye medications. It may interact with other medications, including drugs used to treat depression, HIV, certain antibiotics, antifungal medications, alpha blockers, and oral steroids. Inform your doctor of any other medications you may be taking, including any over-the-counter medications.

Drug Interactions

The combined use of Hidine with other drugs can lead to serious side effects. Therefore, inform your doctor of any other medications or supplements you may be taking. Hidine should not be used with the antibiotics tetracycline, doxycycline, and rifampin.

Food Interactions

Hidine has no known food interactions. However, it is advised to avoid alcohol and grapefruit as they may increase the risk of side effects.

Pregnancy and Lactation Use

It is not known if Hidine is safe for use during pregnancy or lactation. Therefore, it is important to inform your doctor of any pregnancy or lactation periods before using the medication.

Acute Overdose

In case of an overdose, contact a poison control center immediately. Symptoms of an overdose may include abdominal pain, nausea, vomiting, diarrhea, blurred vision, and eye irritation.

Use Directions

Follow the instructions of your doctor when using Hidine. The dosage is usually 1 or 2 drops in each affected eye up to 4 times daily and differs depending upon the severity of symptoms and response to treatment. The medication should be stored at a controlled room temperature between 59-86 degrees F. Avoid letting the bottle touch any surfaces, and keep it away from children's reach.

Storage Conditions

Hidine should be stored at a controlled room temperature between 59-86 degrees F. Keep it away from direct heat, moisture, and light. Avoid letting the bottle touch any surfaces, and keep it away from children's reach.

Volume of Distribution

The volume of distribution for Hidine is approximately 43.9 L/kg.

Half Life

The elimination half-life of Hidine is approximately 6.9 hours.

Clearance

The clearance of Hidine is 4.2-7.7 L/hr/kg.

Here you find in details version of Hidine

Some Frequently Asked Questions About Hidine

What is Hidine?

Hidine is an antihistamine medication primarily used for the treatment of allergic conjunctivitis such as itchy, red, or watery eyes.

What are the side effects of Hidine?

Common side effects of Hidine include headache, blurred vision, dry eyes, bitter or unusual taste in the mouth, and dry mouth.

How should Hidine be stored?

Hidine should be stored at room temperature, away from direct sunlight and out of reach of children.

How often should Hidine be taken?

Hidine should be taken as directed by your doctor, usually 1 to 2 times a day.

What should I do if I miss a dose of Hidine?

If you miss a dose of Hidine, take it as soon as you remember. Do not take a double dose to make up for a missed dose.

Can I take Hidine with other medications?

It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Does Hidine interact with alcohol?

Alcohol and Hidine may interact and lead to increased side effects or decreased effectiveness. It is recommended that you do not drink alcohol while taking Hidine.

What is the recommended dosage of Hidine?

The recommended dosage of Hidine depends on your age, weight, and medical condition. Your doctor will determine the dosage that is best for you.

Is Hidine habit-forming?

Hidine is not habit-forming when taken as directed by a doctor.

Should I avoid certain activities while taking Hidine?

You should avoid driving or operating machinery while taking Hidine, as it can cause blurred vision, which can impair judgment.

Can I get Hidine over the counter?

Hidine is a prescription medication and cannot be purchased over the counter.

Is Hidine safe to take during pregnancy?

Hidine should not be used during pregnancy unless the potential benefit outweighs the potential risks to the fetus.

Will Hidine relieve my symptoms immediately?

Hidine may take several days to start working. It is important to take Hidine regularly to get the most benefit.

How long can I take Hidine for?

The length of treatment with Hidine will depend on your medical condition and response to treatment. It is important to follow your doctor’s instructions when taking Hidine.

Are there any serious side effects I should be aware of?

Serious side effects of Hidine include difficulty breathing, swelling of the face, throat, lips or tongue, and an irregular heartbeat. Seek medical attention immediately if you experience any of these symptoms.

Does Hidine affect fertility in men or women?

It is not known whether Hidine affects fertility in either men or women.

Can Hidine cause hair loss?

Hair loss is not a known side effect of Hidine, but it may occur in some individuals.

Will Hidine cause drowsiness or dizziness?

Hidine may cause drowsiness or dizziness, especially when taken with other medications that can cause drowsiness. It is important to take Hidine with caution and not drive or operate machinery if you experience these symptoms.

Does Hidine cause sweating?

Excessive sweating is not a known side effect of Hidine.

Will Hidine increase my heart rate?

Hidine may increase heart rate in some individuals. Contact your doctor if you experience an irregular or rapid heartbeat.

Is Hidine for short-term or long-term use?

Hidine can be used for either short-term relief of allergic conjunctivitis or for long-term prevention and treatment of chronic allergic conjunctivitis.

How does Hidine work?

Hidine works by blocking the effect of histamine, a natural substance in the body that causes allergic reactions. This reduces swelling and itching in the eyes associated with allergic conjunctivitis.

Is Hidine safe for children?

Hidine is not recommended for use in children younger than 2 years of age. Speak with your doctor before giving Hidine to a child.

Should I discontinue use of Hidine if my symptoms worsen?

If you find that your symptoms are worsening while taking Hidine, you should contact your doctor. Your doctor may adjust your dosage or recommend an alternate medication.

Is Hidine safe to use with contact lenses?

It is recommended that you do not wear contact lenses if you are using Hidine. Contact lenses may trap the Hidine in the eyes, increasing the risk of side effects.

Should I discuss other health conditions with my doctor before taking Hidine?

Yes, it is important to tell your doctor about all health conditions you have before starting Hidine. This includes any allergies, kidney or liver problems, and any other medications you may be taking.

Can Hidine be used to treat dry eyes?

Hidine is not specifically prescribed to treat dry eyes. Speak with your doctor if you are experiencing dry eyes to determine the best treatment plan for you.

Is Hidine safe for people with asthma or other respiratory conditions?

People with asthma or other respiratory conditions should be cautious when taking Hidine. If you experience any difficulty breathing or chest tightness while taking Hidine, contact your doctor.

Does Hidine cause headaches?

Headache is a common side effect of Hidine. If you experience a severe headache or one that lasts for more than a few days, contact your doctor.

Is Hidine habit-forming?

No, Hidine is not habit-forming when taken as prescribed.

Can I take Hidine with other antihistamines?

It is not recommended that you take Hidine with other antihistamines, as this can increase the risk of side effects.

What are the signs of an allergic reaction to Hidine?

Signs of an allergic reaction to Hidine include rash, hives, difficulty breathing, or swelling of the face, lips, tongue, or throat. If you experience any of these symptoms, seek medical attention immediately.

Can Hidine be used to treat hives?

No, Hidine is not recommended for the treatment of hives.

Can Hidine be used to treat itching?

Yes, Hidine can be used to treat itching caused by allergies or other skin conditions.

Can Hidine be used long-term?

Yes, Hidine can be used long-term for the treatment and prevention of chronic allergic conjunctivitis.

What should I do if I experience blurred vision while taking Hidine?

Blurred vision is a common side effect of Hidine. If you experience blurred vision, do not drive or operate machinery and contact your doctor.

Are there any foods or drinks I should avoid while taking Hidine?

You should avoid drinking alcohol while taking Hidine as it may increase the risk of side effects.

What is the most common side effect of Hidine?

The most common side effect of Hidine is headache.

Can Hidine be used to treat insect bites?

No, Hidine is not recommended for the treatment of insect bites.

Can Hidine be used to treat a sinus infection?

No, Hidine is not recommended for the treatment of a sinus infection.

Can I take anti-inflammatory medications while taking Hidine?

It is important to tell your doctor about any medications you are taking before starting Hidine, including anti-inflammatory medications.

Does Hidine have to be taken with food?

Hidine does not have to be taken with food, but if it causes an upset stomach, it may be taken with food or milk.