Gramicidin D
Gramicidin D Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Gramicidin D is a brand name. Its generic name is Gramicidin D.
Gramicidin D: Introduction
Gramicidin D is an antibiotic that is produced by the gut bacterium Bacillus brevis. It is a cationic peptide antibiotic that acts against gram-positive bacteria. Gramicidin D has multiple uses, and is used in ocular, oral, and topical treatments. Gramicidin D is used for the treatment of bacterial infections.
Gramicidin D: Uses
Gramicidin D is used in the treatment of infections caused by gram-positive organisms, including:
- Staphylococcus aureus
- Streptococcus pneumoniae
- Streptococcus pyogenes
- Bacillus subtilis
- Clostridium perfringens
Gramicidin D: Mechanism Of Action
Gramicidin D works by disrupting the bacterial cell wall. Gramicidin D acts by disrupting the cell membrane, which leads to cell death. Gramicidin D also interferes with DNA replication, which, in turn, inhibits bacterial growth.
Gramicidin D: How Long Does It Take To Work?
Gramicidin D begins to work quickly, and should begin to reduce bacterial numbers within a few hours. The full effects of Gramicidin D can be seen in 24-48 hours, depending on the organism being treated.
Gramicidin D: Absorption, Route of Elimination, Dosage, Administration
Gramicidin D is readily absorbed from the gastrointestinal tract after oral administration. Once absorbed, it is quickly eliminated in the urine and feces. The dosage and administration of Gramicidin D depend on the type of infection being treated and the severity of the infection. Gramicidin D should be taken as prescribed by a physician.
Gramicidin D: Side Effects
Gramicidin D is generally well tolerated. Common side effects include gastrointestinal upset, skin rash, and dizziness. If any of these side effects persist or worsen, it is important to contact a physician immediately.
Gramicidin D: Toxicity
Gramicidin D has low toxicity, and is not believed to cause toxicity in humans. Gramicidin D has not been linked to any serious health problems.
Gramicidin D: Precaution, Interaction, Disease Interaction, Drug Interaction
Gramicidin D should be used with caution in patients with known allergies to antibiotics. Gramicidin D may interact with other medications, including anticoagulants, cyclosporine, penicillins, and tetracyclines. Gramicidin D should not be used in patients with liver or kidney disease, as it can cause adverse reactions. Gramicidin D may also interact with other antibiotics or drugs including sulfonamides, macrolides, cephalosporins, and aminoglycosides.
Gramicidin D: Food Interactions, Pregnancy Use, Lactation Use
Gramicidin D has no known food interactions. However, caution should be used when taking Gramicidin D with food, as some foods can interfere with the absorption of antibiotics. Gramicidin D should not be used during pregnancy unless the potential benefits outweigh the risks. Gramicidin D should not be used while breastfeeding, as it can pass through breast milk.
Gramicidin D: Acute Overdose, Contraindication, Use Direction, Storage Condition
Gramicidin D overdose can cause nausea, vomiting, and diarrhea. In the event of an overdose, contact a physician immediately. Gramicidin D should not be used in patients with a known allergy to antibiotics. Gramicidin D should be taken as prescribed by a physician. Gramicidin D should be stored in a cool, dry place away from light and moisture.
Gramicidin D: Volume Of Distribution, Half Life, Clearance
The volume of distribution of Gramicidin D is not known. The half life of Gramicidin D is approximately 4 hours. The clearance of Gramicidin D is not well established.
Gramicidin D: Dosage Information
The dosage of Gramicidin D depends on the type of infection and the severity of the infection. Typical dosage ranges are as follows:
- Oral: 200-400mg every 12 hours.
- Topical: 0.1-1.0% solution applied every 8-12 hours.
- Ocular: 0.5% solution applied every 8-12 hours.
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