Glocef
Glocef Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Glocef is a brand name. Its generic name is Cefixime.
Introduction
Glocef is an antibiotic used to treat a variety of bacterial infections. It belongs to the cephalosporin antibiotics group, and works by killing the bacteria that cause the infection.
Uses
Glocef is used to treat a variety of bacterial infections, including respiratory and urinary tract infections, skin infections, sexually transmitted diseases, and gonorrhea.
Mechanism of Action
Glocef works by interfering with the synthesis of the bacterial cell wall. This prevents the bacteria from forming the protective layer it needs to survive, and eventually causes the bacteria to die.
How Long Does it Take to Work?
Glocef typically starts to work within 48 hours. Depending on the severity and type of infection, it can take up to 7 days or longer for the symptoms to fully resolve.
Absorption
Glocef is absorbed in the small intestine and rapidly distributed throughout the body. Peak concentrations in the blood occur within 1-2 hours after taking a dose.
Route of Elimination
Glocef is eliminated primarily in the urine, with only a small amount being eliminated in the feces.
Dosage
The recommended dosage of cefixime for adults is 100-200 mg every 12 hours, or 400 mg once daily. For pediatric patients, the dose range is 5-10 mg/kg/day, divided every 12 hours. For children younger than 5, the dose should not exceed 400 mg per day.
Administration
Glocef should be taken with food for maximum absorption. It should be taken at the same time every day, and not skipped.
Side Effects
Common side effects of cefixime include nausea, vomiting, diarrhea, rash, dizziness, headache, stomach pain, and vaginitis. If any of these side effects are severe or persist, the patient should immediately seek medical attention.
Toxicity
Glocef is considered to have a low toxicity profile, with no known overdose cases reported. It is important to carefully follow the dosage instructions to avoid potential side effects and drug interactions.
Precaution
Patients with certain allergies or medical conditions should take extra precaution when taking cefixime. Patients allergic to cephalosporin antibiotics, or with kidney or liver problems, should consult their doctor before taking cefixime.
Interactions
Glocef may interact with certain medications, such as antacids or other antibiotics. It is important to tell your healthcare provider about all medications you're taking in order to reduce the risk of potential interactions.
Drug Interactions
Glocef may interact with other medications, including antibiotics, antacids, antidepressants, and diuretics. These medications can decrease the absorption of cefixime, potentially lowering its effectiveness.
Food Interactions
Glocef should be taken with food. Taking it on an empty stomach can decrease its absorption and potentially make it less effective.
Pregnancy Use
Glocef is classified as a pregnancy category B drug, meaning that its safety for use during pregnancy has not yet been established. It should only be used during pregnancy if the benefit outweighs the potential risks.
Lactation Use
Glocef is also classified as a lactation category B drug. The excretion of the drug into breast milk is unknown, and it should be used with caution in breastfeeding mothers.
Acute Overdose
An acute overdose of cefixime is unlikely to cause any serious side effects, but if an overdose is suspected, medical attention should be sought immediately.
Contraindication
Glocef is contraindicated in patients with a known hypersensitivity to the drug. It should also not be used in patients with severe kidney or liver disease.
Use Direction
Glocef should be taken as directed by your doctor. Do not take more than the recommended dose or use for longer than directed.
Storage Condition
Glocef should be stored at room temperature, away from moisture and heat. Keep it in the original container and out of reach of children.
Volume of Distribution
The volume of distribution for cefixime is 0.3 L/kg.
Half Life
The half life of cefixime is approximately 1.5 hours.
Clearance
The clearance of cefixime is 0.2 L/h/kg.
Here you find in details version of Glocef
Some Frequently Asked Questions About Glocef
What is Glocef?
Glocef is an antibiotic used to treat a wide range of bacterial infections, including upper respiratory, urinary tract, and ear infections. It is taken by mouth and is available in capsule and suspension form.
How long does it take for Glocef to work?
The effects of Glocef can typically be seen within 48 hours of taking the medication. However, it may take longer for the infection to fully clear up.
How often should I take Glocef?
Glocef should be taken exactly as prescribed by your doctor. Typically, you will take one dose by mouth once a day, or as directed by your doctor.
Is Glocef safe to take while pregnant?
It is generally considered safe to take Glocef while pregnant as it is unlikely to harm an unborn baby. However, it is important to speak to your doctor before taking any medication while pregnant.
What are the side effects of Glocef?
Common side effects of Glocef include feeling dizzy or lightheaded, nausea, vomiting, diarrhea, and abdominal pain. If you experience any of these side effects, contact your doctor.
What should I avoid while taking Glocef?
You should avoid alcohol and other medications with alcohol while taking Glocef as they can increase the risk of side effects. Additionally, you should avoid taking other antibiotics while taking Glocef as this can decrease the efficacy of the medication.
Can Glocef be used to treat a UTI?
Yes, Glocef is commonly used to treat urinary tract infections (UTIs), as it is an effective antibiotic for various bacterial infections. However, it is important to speak to your doctor before taking any medication for a UTI.
Is Glocef safe for children?
Although Glocef is FDA approved for use in adults, the safety and efficacy of Glocef in children has not been established. Therefore, it is important to speak to your doctor before giving Glocef to a child.
Is Glocef resistant to penicillin?
No, Glocef is not resistant to penicillin. It is a type of cephalosporin antibiotic, which is similar to penicillin in its mode of action.
Can I take Glocef with other medications?
Yes, you can take Glocef with other medications, but it is important to inform your doctor of any other medications you are taking. Additionally, do not take Glocef with any other antibiotics.
What if I miss a dose of Glocef?
If you miss a dose of Glocef, take it as soon as you remember. If it is close to the time for your next dose, skip the missed dose and take your next dose as scheduled.
Can I take Glocef while breastfeeding?
Yes, Glocef is safe to take while breastfeeding. However, it is important to inform your doctor of any medications you are taking while breastfeeding, including any Over The Counter (OTC) medications.
Is Glocef an antibiotic?
Yes, Glocef is an antibiotic used to treat a wide range of bacterial infections.
Can Glocef be used to treat pneumonia?
Yes, Glocef is effective for treating some cases of pneumonia. However, it is important to speak to your doctor to determine the most effective course of treatment.
What type of bacteria does Glocef treat?
Glocef is an effective antibiotic for treating a wide range of bacterial infections, including upper respiratory, urinary tract, and ear infections. It is effective against both gram-negative and gram-positive bacteria.
Is Glocef safe for dogs?
Glocef is not typically used to treat infections in dogs due to the concurrent risks and side effects. It is important to speak to your veterinarian before giving your dog any medication.
Can I take Glocef with milk?
Yes, it is safe to take Glocef with milk. However, you should avoid taking it with calcium-fortified beverages as this can reduce the absorption of the medication.
How do I store Glocef?
Glocef should be stored at room temperature away from light and excessive heat. Once opened, the suspension should be refrigerated and used within 10 days.
What is the dosage of Glocef?
The recommended dosage of Glocef is 400-800mg taken by mouth once daily or as directed by your doctor. It is important to speak to your doctor to determine the correct dosage for your condition.
Is Glocef a sulfa drug?
No, Glocef is not a sulfa drug. Sulfa drugs are sulfonamide antibiotics which contain a sulfonamide group, while Glocef is a cephalosporin antibiotic.
Can Glocef be used to treat gonorrhea?
Yes, Glocef is effective in treating gonorrhea. However, it is important to take the full course of the medication as prescribed by your doctor to ensure the infection is completely cleared.
What should I do if I experience an allergic reaction to Glocef?
If you experience any signs of an allergic reaction to Glocef such as difficulty breathing, rash, itching, or swelling, contact your doctor or seek medical help immediately.
Can I take Glocef with food?
Yes, it is safe to take Glocef with food or immediately after a meal. However, do not take it with calcium-fortified foods or beverages as this can reduce the absorption of the medication.
Can Glocef be used to treat a sinus infection?
Yes, Glocef is effective in treating a range of bacterial sinus infections. However, it is important to speak to your doctor to determine the most effective course of treatment.
Does Glocef have any drug interactions?
Yes, Glocef has been known to interact with certain medications and supplements, including methotrexate, probenecid, and antacids, so it is important to inform your doctor of all medications you are taking.
Does Glocef cause diarrhea?
Yes, Glocef can cause diarrhea as a side effect. If you experience any side effects, contact your doctor.
How long does Glocef stay in your system?
Glocef can remain in your system for up to 24 hours after you take it. Therefore, if you have missed a dose, it is important to take it as soon as possible.
What is the usual course of treatment for Glocef?
The usual course of treatment for Glocef is 7-10 days. It is important to take the full course of the medication as prescribed by your doctor for the infection to be cleared properly.
Is Glocef a penicillin?
No, Glocef is not a penicillin. It is a type of cephalosporin antibiotic, which is similar to penicillin in its mode of action.
Can I take Glocef if I have a penicillin allergy?
Yes, you can take Glocef if you have a penicillin allergy. Glocef is a type of cephalosporin antibiotic which is not related to penicillin.