Fluoximesterona
Fluoximesterona Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Fluoximesterona is a brand name. Its generic name is Fluoxymesterone.
Fluoximesterona
Fluoximesterona is an anabolic steroid that mimics the activity of the male hormone testosterone. It is primarily used to treat certain types of male hypogonadism (low levels of testosterone) to restore normal male hormone levels. It is available in multiple dosage forms, including tablets, intramuscular injection, and topical gel.
Uses For Fluoximesterona
Fluoximesterona is primarily used in the treatment of male hypogonadism. It also has some off-label uses, including treatment of female-to-male gender aspects and delayed puberty in boys.
Mechanism of Action
Fluoximesterona works by mimicking the function of testosterone in the body. It binds to androgen receptors, which allow for the uptake of testosterone into cells. This increases the production of proteins in the body, thereby leading to the development of male features, such as body hair and muscle growth.
How Long Does it Take to Work?
Fluoximesterona usually starts working within a few weeks of starting treatment. However, full effects on testosterone levels may take several months to appear.
Absorption
Fluoximesterona is rapidly and almost entirely absorbed from the gastrointestinal tract after oral administration. After systemic absorption, the compound is distributed to muscle, fatty tissues, brain, and other organs.
Route of Elimination
Fluoximesterona is mainly eliminated by the liver and excreted in the urine and feces.
Dosage
The recommended daily dose of fluoxymesterone is 25-100 mg per day, depending on the severity of symptoms and the response to treatment. It is usually taken by mouth once daily, with or without food. It should be swallowed whole with a full glass of water.
Administration
Fluoximesterona may be taken with or without food. It should be taken at the same time each day. It should not be crushed, chewed, or dissolved in water.
Side Effects
Common side effects of fluoxymesterone may include nausea, vomiting, headache, fever, joint pain, enlarged prostate, male pattern baldness, irregular menstrual periods, and facial hair growth in women.
Toxicity
High doses of fluoxymesterone may increase the risk of liver toxicity, as well as other adverse effects. In case of overdose, immediate medical help should be sought.
Precautions
Fluoximesterona should be used with caution in patients with kidney or liver impairment, diabetes, and heart problems. The safety and efficacy of fluoxymesterone in children or adolescents has not been established.
Interactions
Fluoximesterona should not be used with certain medications, including barbiturates, anticoagulants, and corticosteroids. It should also not be combined with other testosterone supplements as this may increase the risk of side effects.
Disease Interaction
Fluoximesterona may increase the risk of blood-clotting disorders, prostate cancer, and heart attack. It may exacerbate existing conditions such as diabetes, high blood pressure, and sleep apnea.
Drug Interactions
Fluoximesterona may interact with certain medications, including barbiturates, anticoagulants, and corticosteroids. Aspirin, ibuprofen, and other anti-inflammatory medications may increase the risk of side effects.
Food Interactions
Fluoximesterona may interact with certain foods, such as broccoli, Brussels sprouts, and soybeans. It may also interact with alcohol and certain dietary supplements.
Pregnancy Use
Fluoximesterona should not be used during pregnancy. It may harm a developing fetus, and can pass into breast milk.
Lactation Use
Fluoximesterona should not be used by women who are breastfeeding. It may pass into breast milk and harm a nursing baby.
Acute Overdose
Overdose of fluoxymesterone may result in symptoms such as nausea, vomiting, headache, fever, joint pain, and enlarged prostate. Emergency medical assistance should be sought if overdose is suspected.
Contraindication
Fluoximesterona should not be used in patients with known hypersensitivity to it, or to any of its inactive ingredients. It should also not be used in patients with prostate cancer, breast cancer, heart or liver disease, or any other medical conditions.
Use Direction
Fluoximesterona should be used exactly as prescribed by the healthcare provider. The dosage should not be changed without medical advice. The medication should not be stopped abruptly.
Storage Condition
Fluoximesterona should be stored at room temperature, away from direct sunlight, heat, and moisture. It should not be stored in the bathroom.
Volume of Distribution
The volume of distribution of fluoxymesterone is approximately 15.7 L/kg.
Half Life
The half-life of fluoxymesterone is approximately 8-12 hours.
Clearance
The clearance of fluoxymesterone is approximately 0.27-1.2 L/hr/kg.
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