Floxacillin
Floxacillin Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Floxacillin is a brand name. Its generic name is Flucloxacillin.
Introduction
Floxacillin is an antibiotic belonging to the penicillin family. It is used to treat infections caused by both Gram positive and Gram negative bacteria. It is available in most countries either as a generic drug or as branded versions.Uses
Floxacillin is primarily used to treat a wide range of bacterial infections including infections of the respiratory tract, skin, and urinary tract. It is also used to treat some sexually transmitted diseases such as gonorrhea.Mechanism of Action
Floxacillin works by inhibiting synthesis of bacterial cell wall. It attaches itself to enzymes responsible for cross-linking peptidoglycans molecules. This prevents these enzymes from functioning, effectively killing the bacterial cell.How Long Does it Take to Work
Floxacillin should start working within 12 to 24 hours of taking the medicine. However, it is important to take the medication as prescribed, and for the entire course of treatment, in order to get the full benefit.Absorption
Floxacillin is absorbed through the walls of the upper gastrointestinal tract. It is rapidly absorbed, reaching a peak concentration in one hour.Route of Elimination
Floxacillin is eliminated mainly through the urine. It is also excreted in bile.Dosage
Floxacillin is available in various dosage forms and strengths. The dosage usually depends on the type and severity of the infection being treated, as well as the patient’s age, weight, and kidney function. Common oral dosage forms and strengths include 250 mg, 500 mg, and 750 mg capsules. Common IV dosage forms and strengths include 500 mg, 1 g, and 2 g vials. Dosage should be determined by a doctor or pharmacist.Administration
The medication can be taken orally with or without food, or it can be administered intravenously. If administered IV, it should be diluted with a compatible IV solution, such as normal saline, and administered slowly.Side Effect
Common side effects of Floxacillin may include nausea, diarrhea, vomiting, headache, and skin rash or itching. In rare cases it can cause severe allergic reactions or anaphylaxis. Serious side effects, such as watery or bloody diarrhea and flu-like symptoms, may require immediate medical attention.Toxicity
Floxacillin is considered to have relatively low toxicity when taken at the recommended dose. Overdose may lead to nausea, vomiting, abdominal pain, and other symptoms.Precaution
Floxacillin should be taken with caution if you are allergic to other medicines in the penicillin family, or if you have any other allergies. It should also be used with caution if you have preexisting kidney or liver problems.Interaction
Floxacillin can interact with some other medications. It is important to tell your doctor or pharmacist about all medications, vitamins, and supplements you are taking before starting to take this medication.Disease Interaction
Floxacillin should be used with caution if you have certain diseases such as diabetes, kidney disease, blood diseases, or liver disease.Drug Interaction
Floxacillin may interact with other medications such as antacids, birth control pills, and some blood pressure medications.Food Interactions
Floxacillin should be taken with food to minimize gastric irritation.Pregnancy Use
Floxacillin is not recommended for pregnant women due to the potential risk of harm to the fetus.Lactation Use
Floxacillin should not be used during lactation due to the potential risk of compromising the quality of breast milk.Acute Overdose
In the case of an acute overdose, it is important to seek medical attention immediately. Symptoms may include nausea, vomiting, abdominal pain, and other symptoms.Contraindication
Floxacillin is contraindicated in patients who are allergic to penicillins, cephalosporins, or any other antibiotic.Use Direction
Floxacillin should be taken exactly as prescribed by your doctor or pharmacist. It should not be taken longer than the prescribed course of treatment as this increases the risk of developing bacterial resistance.Storage Condition
Floxacillin should be stored at room temperature and away from direct sunlight.Volume of Distribution
Floxacillin has a large volume of distribution. It is distributed into most body tissues and fluids, including saliva, semen, and cerebrospinal fluid.Half Life
The half-life of flucloxacillin is 1.5 - 2 hours.Clearance
Floxacillin is cleared by both renal and non-renal mechanisms. It is primarily cleared by the kidneys, but it is also cleared by metabolism and excretion into bile.Here you find in details version of Floxacillin
Some Frequently Asked Questions About Floxacillin
What is Floxacillin?
Floxacillin is a type of antibiotic, and it belongs to a group of medicines called 'penicillins'. It is used to treat bacterial infections, such as skin, chest, urine, and ear infections caused by susceptible organisms.
What is it used to treat?
Floxacillin is used to treat bacterial infections, such as skin, chest, urinary, and ear infections, caused by susceptible organisms.
How does Floxacillin work?
Floxacillin works by stopping the bacteria from multiplying and killing them. It also helps the body's own natural defenses to fight the infection.
How quickly does Floxacillin work?
Floxacillin usually starts working within a few days and will often work within 24 hours, but it might take slightly longer to get rid of all the bacteria causing the infection.
How long should I take Floxacillin?
It is important to take Floxacillin for as long as your doctor has prescribed it for you. This is usually 5 to 10 days after your symptoms have gone. Stopping the medicine too soon could make the infection come back.
Is Floxacillin the same as Penicillin?
No, Floxacillin is a type of penicillin, but it is a more powerful form of penicillin that is used to treat more serious bacterial infections.
Can I drink alcohol while taking Floxacillin?
It is not advisable to drink alcohol while taking any type of antibiotic. Alcohol can reduce the effectiveness of the antibiotic, and can also increase the risk of side effects such as nausea and vomiting.
Do I need to take Floxacillin with food?
Floxacillin does not need to be taken with food. However, if you experience any stomach discomfort or an upset stomach while taking the medicine, then taking it with food may help.
Can I take Floxacillin while pregnant?
Generally, Floxacillin is safe to take while pregnant, but it is important to speak to your doctor before taking any medication while pregnant.
Does Floxacillin have any side effects?
Floxacillin is generally well tolerated, but some people may experience side effects such as feeling sick, diarrhoea, stomach pain, and allergic reactions. Speak to your doctor if you experience any of these symptoms.
What should I do if I forget to take Floxacillin?
If you forget to take a dose, take it as soon as you remember. If it is close to the time for the next dose, skip the missed dose and take the next one when it is due. Do not take two doses at once.
Is Floxacillin available over the counter?
No, Floxacillin is a prescription-only medicine and is not available over the counter.
Is Floxacillin safe for children?
Floxacillin is generally safe for children, but it is important to speak to your doctor before giving any medication to a child.
Is Floxacillin available as a generic medicine?
Yes, Floxacillin is available in generic form and is usually cheaper than the branded version.
Is it safe to take Floxacillin long-term?
It is not advised to take Floxacillin for an extended period of time because it can cause antibiotic resistance in the body. If you have been prescribed Floxacillin for a long-term infection, make sure to take it as directed.
Can Floxacillin cause an allergic reaction?
Yes, an allergic reaction to Floxacillin is possible. Symptoms of an allergic reaction can include an itchy rash, swelling of the face, tongue, and throat, difficulty breathing, and dizziness. If you experience any of these symptoms, seek medical help immediately.
Can Floxacillin interact with other medicines?
Floxacillin can interact with certain medicines, such as antacids, or other antibiotics. It is important to tell your doctor about any other medicines you are taking before starting Floxacillin.
Can I take ibuprofen while taking Floxacillin?
It is not advised to take ibuprofen while taking Floxacillin as this can make it less effective. Speak to your doctor before taking any medicines while taking Floxacillin.
Can Floxacillin make my skin sensitive to the sun?
Yes, Floxacillin can make your skin more sensitive to sunlight. It is important to wear sunscreen when outside and avoid direct exposure to sunlight.
Does Floxacillin cause drowsiness?
No, Floxacillin does not cause drowsiness. However, some people may experience dizziness, so it is important to be careful when driving or operating machinery.
Can I take Floxacillin for a viral infection?
No, Floxacillin is an antibiotic and only works against bacterial infections. It will not work against a viral infection and should not be taken for one.
What should I do if I experience any side effects with Floxacillin?
If you experience any side effects while taking Floxacillin, speak to your doctor as soon as possible. The side effects should go away after you stop taking the medicine, but if they persist, you should seek medical advice.
Can Floxacillin be used to treat a sinus infection?
Floxacillin can be used to treat a sinus infection if it is caused by bacteria, but it will not be effective against a sinus infection caused by a virus.
Can I take Floxacillin if I have an intolerance to penicillin?
If you have an intolerance to penicillin, it is recommended that you do not take Floxacillin. Speak to your doctor about an alternative medication.
What is the usual dosage of Floxacillin?
The usual dose of Floxacillin is 250-500 mg, taken every 6 hours for adult doses and 250-500 mg, taken every 8 hours for children's doses. The exact dose will depend on your medical condition and the severity of the infection.
Should Floxacillin be taken with water?
Floxacillin can be taken with or without water, but it is important to take it as directed on the patient information leaflet.
Can Floxacillin be used to treat a urinary tract infection?
Yes, Floxacillin is commonly used to treat urinary tract infections caused by susceptible bacteria.
Can Floxacillin treat a tooth infection?
Yes, Floxacillin can be used to treat a tooth infection if it is caused by susceptible bacteria.
Is Floxacillin safe for elderly people?
Yes, Floxacillin is generally safe for elderly people, as long as it is taken as directed. However, it is important to speak to your doctor before taking Floxacillin if you are elderly, as they may need to adjust your dose.
Can Floxacillin cause diarrhea?
Yes, Floxacillin can cause diarrhea as a side effect. If you experience any other symptoms or the diarrhea persists, contact your doctor for advice.
Is Floxacillin safe for people with kidney disease?
Floxacillin is usually safe for people with kidney disease, but it is important to speak to your doctor before taking it. They may need to adjust your dose or monitor your kidney function.
Can I take Floxacillin for a sore throat?
Floxacillin is not usually prescribed for a sore throat, unless it is caused by a bacterial infection. If your sore throat is caused by a bacterial infection, speak to your doctor about the possibility of taking Floxacillin.
Can I take Floxacillin for a chest infection?
Yes, Floxacillin is commonly used to treat chest infections caused by susceptible bacteria.
Can Floxacillin treat an ear infection?
Yes, Floxacillin can be used to treat ear infections caused by susceptible bacteria.
What are the storage instructions for Floxacillin?
Floxacillin should be stored in a cool, dry, and dark place, away from direct sunlight. It should also be kept away from children and pets.
Can I take Floxacillin if I'm breast feeding?
It is generally safe to take Floxacillin while breast feeding, but you should speak to your doctor for advice. There may be an alternative medicine that you can take.
Can Floxacillin be taken with other antibiotics?
No, it is not recommended to take Floxacillin with other antibiotics, as this can reduce its effectiveness. Speak to your doctor before taking any other medicines while taking Floxacillin.
Does Floxacillin cause weight gain?
No, Floxacillin does not cause weight gain.
Can I take Floxacillin with paracetamol?
Yes, it is safe to take paracetamol while taking Floxacillin but do not take any other medicines, unless they have been approved by your doctor.
Is Floxacillin safe for people with diabetes?
Yes, Floxacillin is usually safe for people with diabetes, but it is important to speak to your doctor before taking any medication if you have diabetes.
Can I take Floxacillin on an empty stomach?
Yes, Floxacillin can be taken on an empty stomach. However, if you experience any stomach discomfort or an upset stomach while taking the medicine, then taking it with food may help.
Can Floxacillin be used to treat a skin infection?
Yes, Floxacillin can be used to treat skin infections caused by susceptible bacteria.