Flexi SR

Flexi SR Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Flexi SR is a brand name. Its generic name is Aceclofenac.

Introduction

Flexi SR is a non-steroidal anti-inflammatory drug (NSAID) used to manage pain, swelling, and inflammation due to various medical conditions. It is the racemic mixture of the two forms of a compound. It was developed in 1968 and approved for medical use in 1993.

Uses

Flexi SR is used to treat symptoms of osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis. It is also used in the treatment of musculoskeletal disorders, such as neck and back pain, sports injuries, sprains and strains, tendinitis, and bursitis.

Mechanism of Action

Flexi SR works by blocking the production of prostaglandins, hormones that cause inflammation and pain. By blocking this action, it reduces the pain and inflammation caused by these conditions.

How Long Does It Take to Work?

Flexi SR typically takes up to 2 weeks for its effect to be fully manifested. However, most patients experience relief within a few days.

Absorption

Flexi SR is rapidly absorbed from the gastrointestinal tract. It is metabolized in the liver and excreted in the urine and feces.

Route of Elimination

Flexi SR is secreted in the urine and feces. It is also partially metabolized by the liver.

Dosage

Flexi SR is available in 50 mg, 100 mg, and 200 mg doses. The recommended dose is one to two tablets taken orally every 8-12 hours as needed for pain relief. The maximum daily dose is 800 mg per day. The dose may be increased or decreased based on individual response and tolerance.

Administration

Flexi SR tablets should be taken orally, with or without food, as directed by your doctor. The tablets should be swallowed whole and should not be chewed or crushed.

Side Effects

Common side effects of Flexi SR include gastrointestinal discomfort, nausea, headache, dizziness, and rash. Serious side effects include difficulty breathing, chest pain, and liver or kidney problems. Contact your doctor if you experience severe or persistent side effects.

Toxicity

Flexi SR is generally well-tolerated, however, overdoses can result in serious toxicity. Symptoms of overdose include blurred vision, difficulty breathing, confusion, seizures, and coma. Seek immediate medical attention if you or someone you know has overdosed on this medication.

Precaution

Flexi SR should be taken with caution if you have a history of kidney, liver, or gastrointestinal disorder, asthma, dehydration, or blood clotting disorder. You should also avoid taking alcohol or other medications that can irritate the stomach while taking aceclofenac.

Interactions

Flexi SR may interact with certain other medications. Be sure to inform your doctor of any medications, supplements, or vitamins you are currently taking. This medication may also interact with other medical conditions or lifestyle choices.

Drug Interactions

Flexi SR can interact with certain other medications, including anti-inflammatory drugs, antidepressants, blood thinners, antibiotics, antifungal medications, and vitamin supplements. Be sure to tell your doctor and pharmacist about all medications you are currently taking, including any over-the-counter medications.

Food Interactions

Flexi SR may interact with certain foods. It is important to talk to your doctor about any dietary restrictions or food interactions that may occur when taking this medication.

Pregnancy Use

Flexi SR should not be used during pregnancy as it may cause harm to the fetus. Women who are pregnant or planning to become pregnant should not take this medication.

Lactation Use

Flexi SR should not be used during lactation as it may be secreted into breast milk. Women who are breastfeeding should not take this medication.

Acute Overdose

Overdose of aceclofenac can be potentially life-threatening. Symptoms of overdose include, blurred vision, difficulty breathing, confusion, seizures, and coma. Seek immediate medical attention if you or someone you know has overdosed on this medication.

Contraindication

Flexi SR should not be used in people with a history of stomach or intestinal ulcer, liver and kidney disease, and patients with a history of hypersensitivity to other drugs including Flexi SR.

Use Direction

Flexi SR should be taken exactly as prescribed by your doctor. Do not take more or less of the medication than directed. Do not take the medication more or less frequently than directed.

Storage Condition

Flexi SR should be stored at room temperature, away from light, moisture, and heat. Keep away from children and pets.

Volume of Distribution

Flexi SR has a large volume of distribution and is widely distributed throughout the body.

Half Life

The elimination half-life of aceclofenac is approximately 6 hours.

Clearance

Flexi SR is cleared from the body primarily by the kidneys. The oral clearance of the drug is approximately 40 mL/min.

Here you find in details version of Flexi SR

Some Frequently Asked Questions About Flexi SR

What is Flexi SR?

Flexi SR is a non-steroidal anti-inflammatory drug (NSAID) used for treating pain and inflammation in conditions such as rheumatoid arthritis, ankylosing spondylitis, and osteoarthritis.

What is the mechanism of action of Flexi SR?

Flexi SR is thought to work by inhibiting the activity of the enzyme cyclooxygenase (COX). Inhibition of COX leads to decreased synthesis of pro-inflammatory and painmediating prostaglandins, resulting in a reduction in inflammation and pain.

What is the dosage of Flexi SR?

The recommended adult dose of Flexi SR is 100 to 200 mg twice daily or as directed by the physician.

What are the side effects of Flexi SR?

The common side effects of Flexi SR include stomach upset, heartburn, nausea, vomiting, diarrhea, drowsiness, headache, constipation, joint pain, rash and itching.

What should be avoided while taking Flexi SR?

Alcohol should be avoided while taking Flexi SR as it can increase the risk of stomach ulcers and bleeding. ACE inhibitors, anticoagulants, diuretics, NSAIDs, and corticosteroids should also be avoided while taking Flexi SR.

Can Flexi SR be used for migraine?

Flexi SR is not usually recommended for the treatment of migraine headaches, although some patients may find it to be effective. Patients should discuss this with their doctor to determine if Flexi SR is an appropriate treatment.

Can I take Flexi SR with paracetamol?

Yes, it is safe to take Flexi SR with paracetamol. However, it is important to follow the dosages as prescribed by your doctor, and not to exceed the recommended dosages.

Can I take Flexi SR during pregnancy?

Flexi SR is not recommended during the first and third trimester of pregnancy. There is limited data on its use and safety during the second trimester of pregnancy, and it should be used only if the potential benefits outweigh the risks.

Is Flexi SR a muscle relaxant?

No, Flexi SR is not a muscle relaxant. It is a non-steroidal anti-inflammatory drug (NSAID) used to reduce pain and inflammation in conditions such as rheumatoid arthritis, ankylosing spondylitis, and osteoarthritis.

Can Flexi SR be used for headaches?

Flexi SR is not usually recommended for the treatment of headache. Patients should discuss this with their doctor to determine if Flexi SR is an appropriate treatment.

What are the serious side effects of Flexi SR?

Serious side effects of Flexi SR include signs of allergic reactions (hives, difficulty breathing, swelling of the face, lips, tongue, or throat), chest pain, increased blood pressure, shortness of breath, and bloody or black, tarry stools.

What is the difference between Flexi SR and Ibuprofen?

Flexi SR and ibuprofen are both non-steroidal anti-inflammatory drugs (NSAIDs) used for reducing pain and inflammation. The main difference between them is that Flexi SR is thought to have fewer gastrointestinal side effects than ibuprofen.

Can I take Flexi SR if I have high blood pressure?

Yes, you can take Flexi SR if you have high blood pressure. However, it is important to follow the dosages as prescribed by your doctor, and not to exceed the recommended dosages.

Is Flexi SR safe?

Flexi SR is generally safe and well-tolerated when taken at prescribed doses. However, it can cause side effects such as stomach upset, heartburn, nausea, vomiting, diarrhea, drowsiness, headache, constipation, joint pain, rash and itching.

Can Flexi SR be used to treat fever?

No, Flexi SR is not usually recommended for the treatment of fever. It is used to reduce pain and inflammation associated with conditions such as rheumatoid arthritis, ankylosing spondylitis, and osteoarthritis.

How long does Flexi SR take to work?

Flexi SR usually starts to work within a few hours of taking it. Maximum effects are usually seen within 1-2 weeks.

Can I take Flexi SR with warfarin?

No, it is not recommended to take Flexi SR with warfarin as it could increase the risk of bleeding. If you are taking warfarin then you should discuss this with your doctor before taking Flexi SR.

What is the maximum daily dose of Flexi SR?

The maximum daily dose of Flexi SR is 400 mg per day. Higher doses are not recommended and patients should not exceed the recommended dose.

Is Flexi SR available over the counter?

No, Flexi SR is a prescription medication available only through a doctor's prescription.

Is Flexi SR a strong painkiller?

Flexi SR is a medium strength painkiller used for treating pain and inflammation in conditions such as rheumatoid arthritis, ankylosing spondylitis, and osteoarthritis.

Can Flexi SR be used to treat gout?

Yes, Flexi SR can be used to treat gout. However, it is important to follow the dosage as prescribed by the doctor and not to exceed the recommended dosage.

Can Flexi SR be taken with food?

Yes, it is generally recommended to take Flexi SR with food or after meals to reduce the risk of stomach upset. It is important to follow your doctor's instructions when taking this medication.

Can I take Flexi SR before surgery?

No, it is not recommended to take Flexi SR before surgery as it may increase the risk of bleeding. You should discuss this with your doctor before taking this medication.

What should be done in case of an overdose?

If an overdose of Flexi SR is suspected then medical attention should be sought immediately. Symptoms of an overdose may include nausea, vomiting, dizziness, abdominal pain, and drowsiness.

What precautions should I take while using Flexi SR?

It is important to follow all the instructions and precautions provided by the doctor while taking Flexi SR. It is also important to keep your doctor updated about any medical conditions you have and be aware of any medications, supplements, or herbal remedies you are taking that could interact with Flexi SR.

What drug interactions can occur when taking Flexi SR?

Flexi SR may interact with certain drugs, such as ACE inhibitors, anticoagulants, diuretics, NSAIDs, and corticosteroids. It is important to discuss with your doctor any medications, supplements, or herbal remedies you are taking, to prevent any potential drug interactions.

Is Flexi SR safe for long-term use?

Flexi SR is generally safe when taken for a short period of time. Long-term use of Flexi SR can increase the risk of side effects, such as gastrointestinal bleeding, increased risk of heart attack, stroke, and kidney damage. If you are taking Flexi SR for a long-term period, it is important to discuss this with your doctor.

Can Flexi SR cause anemia?

Yes, long-term use of Flexi SR can cause anemia due to decreased production of red blood cells. If you are taking Flexi SR for long-term use, it is important to discuss with your doctor about the potential risks of anemia.

Can Flexi SR cause liver damage?

Yes, Flexi SR can cause liver damage in rare cases. If you experience any signs of liver damage such as yellowing of the eyes or skin, dark urine, or abdominal pain, you should seek medical attention immediately.

Can Flexi SR cause kidney damage?

Yes, long-term use of Flexi SR can cause kidney damage in rare cases. If you experience any signs of kidney damage such as decreased urination, nausea, vomiting, or fluid retention, you should seek medical attention immediately.

Can Flexi SR cause weight gain?

No, Flexi SR does not usually cause weight gain. However, it is possible for certain side effects, such as abdominal pain, nausea, and vomiting, to lead to decreased appetite and weight loss.

Can I take Flexi SR with aspirin?

No, it is not recommended to take Flexi SR with aspirin as it may increase the risk of stomach ulcers and bleeding. If you are taking aspirin then you should discuss this with your doctor before taking Flexi SR.

Can I take Flexi SR for menstrual cramps?

Yes, Flexi SR can be used to treat mild to moderate menstrual cramps. However, it is important to follow the dosage as prescribed by the doctor and not to exceed the recommended dosage.

Does Flexi SR cause drowsiness?

Yes, Flexi SR may cause drowsiness. If you experience drowsiness after taking this medication then it is important to avoid activities that require alertness such as driving or operating machinery.

Does Flexi SR interact with warfarin?

Yes, Flexi SR can interact with warfarin and increase the risk of bleeding. If you are taking warfarin then you should discuss this with your doctor before taking Flexi SR.

What is the onset of action of Flexi SR?

The onset of action of Flexi SR is usually within a few hours of taking it. Maximum effects are usually seen within 1-2 weeks.

How long does Flexi SR take to work?

The effects of Flexi SR may take a few hours to be felt. Maximum effects are usually seen within 1-2 weeks.

Is Flexi SR safe for children?

Flexi SR is not recommended for use in children under 12 years of age. If a child needs to take this medication then it should be taken only under the supervision of a doctor.

Can Flexi SR be taken with food?

Yes, it is generally recommended to take Flexi SR with food or after meals to reduce the risk of stomach upset. It is important to follow your doctor's instructions when taking this medication.

What is the half-life of Flexi SR?

The half-life of Flexi SR is approximately 8 to 12 hours.

Is Flexi SR addictive?

No, Flexi SR is not addictive.

Can I take Flexi SR if I have asthma?

Yes, you can take Flexi SR if you have asthma. However, it is important to discuss this with your doctor to ensure that Flexi SR is