Febuxostat Accord

Febuxostat Accord Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Febuxostat Accord is a brand name. Its generic name is Febuxostat.

Introduction

Febuxostat Accord is used to reduce uric acid levels in adult patients with chronic gout. It is available in both tablet and capsule form. It is manufactured in the United States by Zydus Cadila.

Uses for

Febuxostat Accord is used to reduce the uric acid levels in adult patients with chronic gout, and help reduce flares of gout pain and reduce the need for gout medication.

Mechanism of Action

Febuxostat Accord works by inhibiting xanthine oxidase, an enzyme involved in the production of uric acid. By inhibiting this enzyme, it helps to reduce the levels of uric acid in the blood.

How Long Does it Take to Work?

It usually takes 1-2 weeks for Febuxostat Accord to reduce levels of uric acid. It may take longer for some patients to experience a reduction in gout pain.

Absorption

Febuxostat Accord is well absorbed after oral administration, with the maximum levels reached in the blood in 3-5 hours.

Route of Elimination

Febuxostat Accord is eliminated primarily through the kidneys, with over 80% of the administered dose excreted in urine.

Dosage

The usual dose for adults is 40-80 mg once daily or 40 mg twice a day. The selected dosage should be individualized. The dose may be increased or decreased based on response to therapy. For patients with mild hepatic impairment, a maximum daily dose of 40 mg should not be exceeded. For patients with moderate or severe hepatic impairment, a maximum daily dose of 20 mg should not be exceeded.

Administration

Febuxostat Accord should be taken by mouth as a whole capsule or tablet, with or without food.

Side Effect

The most common side effects of Febuxostat Accord include headache, diarrhea, nausea, vomiting, stomach pain, and rash. In rare cases, serious liver injury, heart attack, and allergic reactions have been reported.

Toxicity

Febuxostat Accord is generally well tolerated when used as prescribed. In rare cases, serious liver injury, heart attack, and allergic reactions have been reported.

Precaution

Patients should be monitored for elevated liver enzymes, and stopped if an increase is detected. Febuxostat Accord should not be used in patients with severe liver or kidney diseases.

Interaction

Febuxostat Accord may interact with other medications, including diuretics, nonsteroidal anti-inflammatory drugs (NSAIDS), and aspirin. Patients should inform their healthcare provider of any other medications they are taking.

Disease Interaction

Febuxostat Accord should not be used in patients with a known hypersensitivity to the drug, severe liver or kidney impairment, or moderate to severe heart failure.

Drug Interaction

Febuxostat Accord may interact with other medications, including diuretics, NSAIDS, warfarin, and aspirin. Patients should inform their healthcare provider of any other medications they are taking.

Food Interaction

Febuxostat Accord should be taken with food or on an empty stomach.

Pregnancy Use

Febuxostat Accord should not be used during pregnancy unless specifically indicated.

Lactation Use

It is not known whether Febuxostat Accord is excreted in human milk. So, Febuxostat Accord should not be used in the lactating women unless specifically indicated.

Acute Overdose

Symptoms of an acute overdose include confusion, dizziness, nausea, vomiting, and abdominal pain. Seek medical attention immediately if an overdose is suspected.

Contraindication

Febuxostat Accord is contraindicated in patients with a known hypersensitivity to the drug, severe liver or kidney impairment, or moderate to severe heart failure.

Use Direction

Follow the directions on the prescription label carefully and take Febuxostat Accord exactly as prescribed. The usual dose for adults is 40-80 mg once daily or 40 mg twice a day.

Storage Condition

Store at room temperature in a dry, dark place.

Volume of Distribution

Febuxostat Accord is widely distributed in body tissues and organs.

Half Life

The half-life of Febuxostat Accord is 12-15 hours.

Clearance

Febuxostat Accord is eliminated primarily through the kidneys, with over 80% of the administered dose excreted in urine.

Here you find in details version of Febuxostat Accord

Some Frequently Asked Questions About Febuxostat Accord

What is Febuxostat Accord?

Febuxostat Accord is a medication used to lower high levels of uric acid in the blood. It is a xanthine oxidase inhibitor, which means it helps to block the production of uric acid in the body. It is used to treat gout and chronic gouty arthritis.

How does Febuxostat Accord work?

Febuxostat Accord works by inhibiting the enzyme xanthine oxidase, which is responsible for the production of uric acid in the body. By inhibiting this enzyme, it helps to reduce the production of uric acid, which is the cause of gout and gouty arthritis.

What is the recommended dose of Febuxostat Accord?

The recommended dose of Febuxostat Accord is 80mg once daily. For patients with certain conditions, the dose may be increased to 120 mg per day. It is important to follow your doctor's instructions carefully when taking Febuxostat Accord.

What are the side effects of Febuxostat Accord?

The most common side effects of Febuxostat Accord include nausea, diarrhea, abdominal pain, indigestion, and headache. Other more serious side effects include a severe allergic reaction (anaphylaxis), liver damage, and decreased blood cell counts.

Can Febuxostat Accord be taken with other medications?

Febuxostat Accord can potentially interact with other medications. Therefore, it is important to tell your doctor about any medications you are taking when discussing Febuxostat Accord. Your doctor will then advise on whether or not it is safe to take the medication with other medications.

Should Febuxostat Accord be taken with food?

Febuxostat Accord can be taken with or without food. However, it is important to follow your doctor's instructions when taking the medication.

Can Febuxostat Accord be taken with alcohol?

It is not recommended to take Febuxostat Accord with alcohol as this can increase the risk of side effects. If you plan on drinking alcohol while taking Febuxostat Accord, it is best to speak to your doctor for advice.

Can Febuxostat Accord cause an allergic reaction?

It is possible to have an allergic reaction to Febuxostat Accord. Symptoms of an allergic reaction include rash, itching, hives, swelling of the face, lips, tongue, or throat, difficulty breathing, or tightness in the chest. If you experience any of these symptoms while taking Febuxostat Accord, seek medical attention immediately.

Can pregnant women take Febuxostat Accord?

It is not recommended for pregnant women to take Febuxostat Accord as it is not known whether it is safe during pregnancy. Therefore, it is important to speak to your doctor before taking this medication if you are pregnant.

Can Febuxostat Accord be used in children?

Febuxostat Accord is not recommended for use in children under the age of 18. If you think your child may benefit from taking Febuxostat Accord, speak to your doctor for advice.

Can Febuxostat Accord cause joint pain?

Febuxostat Accord is not known to cause joint pain, however, if you experience joint pain while taking this medication it is important to speak to your doctor for further advice.

How long does it take for Febuxostat Accord to work?

It usually takes a few days to a few weeks for Febuxostat Accord to start having an effect. However, it can take up to 3 months for Febuxostat Accord to reach full effect, so it is important to follow your doctor's advice and instructions when taking the medication.

Does Febuxostat Accord lower uric acid levels permanently?

Febuxostat Accord does not lower uric acid levels permanently. However, if taken regularly it can help to keep uric acid levels down and prevent future flare ups.

Are there any new drugs similar to Febuxostat Accord?

Yes, there are several new drugs similar to Febuxostat Accord that are currently in clinical trials. These drugs are generic versions of Febuxostat Accord and are intended to provide the same efficacy and safety as the current drug.

Does Febuxostat Accord interact with other medications?

Yes, Febuxostat Accord can potentially interact with other medications. It is important to tell your doctor about any other medications you are taking when discussing Febuxostat Accord.

Can Febuxostat Accord be taken long-term?

Yes, Febuxostat Accord can be taken long-term, however, it is important to follow your doctor's instructions carefully when taking this medication.

Is Febuxostat Accord covered by insurance?

It depends on the type of insurance coverage you have. Contact your insurance provider to find out whether or not Febuxostat Accord is covered by your plan.

What are the possible side effects of Febuxostat Accord?

The most common side effects of Febuxostat Accord include nausea, diarrhea, abdominal pain, indigestion, and headache. Other more serious side effects include a severe allergic reaction (anaphylaxis), liver damage, and decreased blood cell counts.

Can Febuxostat Accord get rid of gout?

Febuxostat Accord can help to reduce the symptoms of gout, however, it is not a cure for gout. It is important to follow your doctor's instructions when taking this medication.

How long should I take Febuxostat Accord?

Your doctor will advise on how long you should take Febuxostat Accord for. It is important to follow your doctor's instructions carefully when taking this medication.

Does Febuxostat Accord have any drug interactions?

Yes, Febuxostat Accord can potentially interact with other medications. It is important to tell your doctor about any other medications you are taking when discussing Febuxostat Accord.

Can Febuxostat Accord be taken with other medicines for gout?

Yes, Febuxostat Accord can be taken with other medicines for gout. However, it is important to follow your doctor's advice when combining this medication with other treatments for gout.

Can I take Febuxostat Accord while pregnant?

It is not recommended for pregnant women to take Febuxostat Accord as it is not known whether it is safe during pregnancy. Therefore, it is important to speak to your doctor before taking this medication if you are pregnant.

Can Febuxostat Accord be used to treat other conditions aside from gout?

No, Febuxostat Accord is only approved to treat gout and chronic gouty arthritis. It is not approved for the treatment of any other conditions.

Are there any foods that should be avoided if taking Febuxostat Accord?

Yes, foods high in purines and alcoholic beverages should be avoided if taking Febuxostat Accord. Purines are found in high levels in certain foods such as organ meats, anchovies, herring, mackerel, and red meats. Alcohol can increase the risk of side effects.

Can I use Febuxostat Accord to reduce joint pain?

Febuxostat Accord is not used to reduce joint pain, however it can help to reduce the symptoms of gout, which can help to improve joint pain. It is important to follow your doctor's instructions when taking this medication.

What is the recommended dose of Febuxostat Accord?

The recommended dose of Febuxostat Accord is 80mg once daily. For patients with certain conditions, the dose may be increased to 120 mg per day. It is important to follow your doctor's instructions carefully when taking Febuxostat Accord.

Is Febuxostat Accord safe for elderly people?

Yes, Febuxostat Accord is generally safe to use for elderly people, however, it is important to speak to your doctor about the risks and benefits before starting treatment.

Can I take Febuxostat Accord with other pain medications?

Yes, Febuxostat Accord can be taken in combination with other pain medications. However, it is important to tell your doctor about all medications you are taking when discussing Febuxostat Accord.

Is Febuxostat Accord the same as allopurinol?

No, Febuxostat Accord and allopurinol are different medications. Both are used to treat gout and chronic gouty arthritis, but they work differently. It is important to follow your doctor's advice when deciding which medication to take.

Should I avoid strenuous exercise if taking Febuxostat Accord?

Yes, it is recommended to avoid strenuous exercise when taking Febuxostat Accord as it can increase the risk of side effects. If you plan to exercise, it is best to speak to your doctor for advice.

Can Febuxostat Accord cause kidney stones?

It is possible to develop kidney stones while taking Febuxostat Accord, however this is usually rare. If you experience any symptoms of kidney stones (e.g., pain in the back or side, blood in the urine), seek medical attention immediately.

What should I do if I forget to take a dose of Febuxostat Accord?

If you forget to take a dose of Febuxostat Accord, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue to take the medication as usual.

Do I need to have regular blood tests while taking Febuxostat Accord?

Yes, it is important to have regular blood tests while taking Febuxostat Accord. Your doctor will advise on how often to have your blood tested in order to monitor your progress.

Can I take Febuxostat Accord if I have liver disease?

It is not recommended for people with moderate to severe liver disease to take Febuxostat Accord. If you have liver disease, speak to your doctor for advice.

Does Febuxostat Accord affect other organs in the body?

Febuxostat Accord is not known to affect other organs in the body, however, as with any medication, it is important to follow your doctor's instructions carefully when taking this medication.

Does Febuxostat Accord cause weight gain?

Febuxostat Accord is not known to cause weight gain, however, if you experience any changes in your weight or appetite while taking this medication, it is important to speak to your doctor for advice.

Can Febuxostat Accord be used with other gout treatments?

Yes, Febuxostat Accord can be used in combination with other treatments for gout. Speak to your doctor about the risks and benefits of combining this medication with other treatments.

How often should I take Febuxostat Accord?

The recommended dose of Febuxostat Accord is 80mg once daily. For patients with certain conditions, the dose may be increased to 120 mg per day. It is important to follow your doctor's instructions carefully when taking Febuxostat Accord.

Does Febuxostat Accord work right away?

It usually takes a few days to a few weeks for Febuxostat Accord to start having an effect. However, it can take up to 3 months for Febuxostat Accord to reach full effect, so it is important to follow your doctor's advice and instructions when taking the medication.

What should I do if I experience side effects with Febuxostat Accord?

If you experience any side effects while taking Febuxostat Accord, it is important to speak to your doctor for advice. You may need to adjust the dose or stop taking the medication depending on the severity of the side effects.

What should I do if I miss a dose of Febuxostat Accord?

If you forget to take a dose of Febuxostat Accord, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue to take the medication as usual.

What is the best way to take Febuxostat Accord?

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