Evista
Evista Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Evista is a brand name. Its generic name is Raloxifene.
Evista Introduction
Evista is a selective estrogen receptor modulator (SERM), also known as a “designer estrogen,” approved for use in postmenopausal women for both the prevention and treatment of osteoporosis and for decreasing the risk of breast cancer. It works by competing with estradiol for binding sites on the estrogen receptor.Uses For
Evista is used for the prevention and treatment of osteoporosis in postmenopausal women. It is also used to reduce the risk of invasive breast cancer in postmenopausal women who have osteoporosis or who are at high risk for breast cancer.Mechanism of Action
Evista works by blocking the effects of the hormone estrogen on certain tissues in the body. This blocking effect is known as selective estrogen receptor modulator (SERM) activity. Evista binds to estrogen receptors and blocks the hormone’s actions in the uterus, breast, and other tissues.How Long Does it Take to Work?
Evista generally takes 6 to 12 months to start working. The bone-building effects may continue for up to 5 years after use is stopped.Absorption
Evista is well absorbed and reaches peak concentrations 2 to 4 hours after administration.Route of Elimination
Evista is primarily metabolized by the liver, and the metabolites are eliminated from the body largely via the kidney.Dosage
For the treatment and prevention of postmenopausal osteoporosis, the recommended dose of raloxifene is 60 mg once daily by mouth.Administration
Evista is available in a tablet form to be taken orally. The tablets should be taken with a full glass of water and should not be chewed or crushed.Side Effects
The most common side effects of raloxifene are hot flashes, leg cramps, increased sweating, constipation, and sleep disturbances. Less commonly, raloxifene has been linked to other side effects such as headache, gastrointestinal upset, dizziness, and fatigueToxicity
Evista is generally well tolerated when taken as directed, but serious toxicity has been reported in rare cases. The most common signs of overdose are nausea, vomiting, and abdominal pain.Precautions
Evista may interact with other medications, including certain antibiotics, antipsychotics, and anticoagulants and may increase the risk of stroke, blood clots, and heart attack. It is important to talk to your healthcare provider about any other medications and supplements you are taking before using raloxifene.Interaction
Evista can interact with some medications, including certain antibiotics, antipsychotics, and anticoagulants. These interactions may increase the risk of stroke, blood clots, and heart attack. It is important to talk to your healthcare provider about any other medications and supplements you are taking before using raloxifene.Disease Interaction
Evista may interact with certain diseases, including certain types of cancer, coronary artery disease, and stroke. Tell your healthcare provider if you have any of these conditions before starting raloxifene.Drug Interaction
Evista may interact with certain drugs, such as certain antibiotics, antipsychotics, and anticoagulants. These interactions may increase the risk of stroke, blood clots, and heart attack. It is important to talk to your healthcare provider about any other medications and supplements you are taking before using raloxifene.Food Interactions
Evista can interact with certain foods, such as grapefruit and grapefruit juice, which may increase the risk of side effects. It is important to talk to your healthcare provider before eating any foods that may interact with raloxifene.Pregnancy Use
Evista should not be used during pregnancy, as it may be harmful to the fetus.Lactation Use
Evista should not be used while breastfeeding, as it may harm the baby.Acute Overdose
Signs of an acute overdose of raloxifene may include nausea, vomiting, and abdominal pain. If you suspect an overdose of raloxifene, contact your healthcare provider or nearest emergency room immediately.Contraindication
Evista should not be used in people who are allergic to it or to any other ingredients in the medication. Additionally, raloxifene should not be used in women who are pregnant or breastfeeding or in people with a history of blood clots, stroke, or liver disease.Dose Direction
Evista is taken orally by mouth once a day, with or without food. The dose for the treatment and prevention of postmenopausal osteoporosis is 60 mg per day.Storage Condition
Evista should be stored at room temperature, away from heat and moisture. It should be kept out of the reach of children and pets.Volume of Distribution
The volume of distribution of raloxifene is approximately 26 liters.Half Life
The half-life of raloxifene is approximately 29 hours.Clearance
The clearance of raloxifene is approximately 5.8 ml/min/kg.Here you find in details version of Evista
Some Frequently Asked Questions About Evista
What is Evista?
Evista is a prescription medication that is used to treat and prevent osteoporosis in postmenopausal women. It is also used to reduce the risk of invasive breast cancer in certain women who are at high risk for the disease. Evista works by partially acting like the hormone estrogen in the body.
What does Evista treat?
Evista is used to treat and prevent osteoporosis in postmenopausal women and to reduce the risk of invasive breast cancer in certain women who are at high risk for the disease.
What are the side effects of Evista?
Common side effects of Evista include hot flashes, leg cramps, joint pain, tiredness, nausea, constipation, gas, stomach pain, and weight changes. Some serious side effects include signs of an allergic reaction, joint problems, vision changes, and swelling of your hands or feet.
How do I take Evista?
Evista usually comes in the form of a tablet. It is usually taken once a day with or without food. Make sure you follow the instructions on the label and do not take more or less than your doctor prescribed.
What if I forget to take my Evista?
If you forget to take your dose of Evista, take it as soon as you remember, unless it is almost time for your next dose. In that case, skip the missed dose and take your next dose at the regular time.
Are there any drug interactions I should be aware of with Evista?
Yes, certain medications may interact with Evista, including certain antibiotics, birth control pills, and anticoagulants. Be sure to tell your doctor about any other medications you are taking before starting Evista.
Is Evista safe?
Evista is generally safe when taken as prescribed. However, it can cause serious side effects in some people, including a serious allergic reaction, blood clots, and worsening of endometriosis. Be sure to talk to your doctor about any possible risks before taking Evista.
Does Evista cause weight gain?
It is not known if Evista causes weight gain. Some people may experience minor weight changes while taking Evista, but this is not a common side effect of the drug. Talk to your doctor if you have any concerns.
How long does it take for Evista to work?
Evista begins to work within a few days of starting the medication. However, it may take several weeks or months to experience the full benefits of the drug.
Does Evista cause headaches?
Headaches are not a common side effect of Evista. However, some people may experience mild headaches while taking the drug. If you experience severe or persistent headaches while taking Evista, talk to your doctor.
Is Evista safe to take while breastfeeding?
No, it is not recommended to take Evista while breastfeeding. It is not known if the drug passes into breast milk and could potentially harm a nursing infant. Talk to your doctor about the best options for you.
How long can I take Evista?
How long you take Evista depends on your individual needs. Your doctor will decide how long you should take the medication.
Can I drink alcohol while taking Evista?
It is generally not recommended to drink alcohol while taking Evista. Alcohol can increase the risk of side effects from this medication, so it is best to avoid alcohol while taking it.
Is Evista a hormonal medication?
No, Evista is not a hormone. It works by partially acting like the hormone estrogen in the body.
How does Evista work?
Evista works by partially acting like the hormone estrogen in the body. It helps to reduce the risk of osteoporosis and invasive breast cancer in certain women.
Will Evista help with joint or muscle pain?
Evista may help to relieve joint and muscle pain caused by osteoporosis. However, it is not approved for this use. Talk to your doctor about other options if you are experiencing joint or muscle pain.
Does Evista help with hot flashes?
Yes, Evista may help with hot flashes. It is not approved for this use, but some studies have found that it may help reduce the frequency and severity of hot flashes in some postmenopausal women.
Can Evista help improve my bone density?
Yes, Evista can help improve your bone density. Studies have found that it can increase bone density in the spine and hips, and reduce the risk of fractures in postmenopausal women.
What is the recommended dosage of Evista?
The recommended dosage of Evista depends on your individual needs. Your doctor will decide the best dosage for you. The usual starting dose of Evista is 60 mg once a day.
Should I take Evista with food?
Evista can be taken with or without food. It is important to take it the same way each day to get the most benefit from the medication.
Can Evista cause constipation?
Yes, constipation is a common side effect of Evista. If you become constipated while taking Evista, be sure to drink plenty of fluids and eat a high-fiber diet.
Should I take any other medications while taking Evista?
Yes, you may need to take other medications while taking Evista, such as calcium and vitamin D supplements. Talk to your doctor about the best medications for you.
Can I take Evista with other osteoporosis medications?
Yes, it is safe to take Evista with other osteoporosis medications. Be sure to tell your doctor about any other medications you are taking before taking Evista.
What type of blood tests should I get while taking Evista?
Your doctor may recommend that you have a complete blood count (CBC) and some liver tests before and during treatment with Evista. These tests can help to monitor your health while taking the medication.
Are there any other uses for Evista?
Evista is approved to treat and prevent osteoporosis and to reduce the risk of invasive breast cancer in certain women at high risk for the disease. It is not approved for any other uses.
Is there a generic version of Evista?
Yes, there is a generic version of Evista called Evista. It is the same medication as Evista but is available at a lower cost.
Should I take Evista if I'm pregnant or planning to become pregnant?
Evista is not recommended for use in pregnant women. Talk to your doctor about the best options for you if you are pregnant or planning to become pregnant.
I'm 65 and have post-menopausal osteoporosis. Can I still take Evista?
Yes, Evista is approved for use in postmenopausal women. Talk to your doctor about whether Evista is right for you.
How long should I stay on Evista?
How long you stay on Evista depends on your individual needs. Generally, Evista should be taken for as long as it is helping to prevent fractures and/or reduce the risk of breast cancer. Talk to your doctor about the best course of action for you.
Can I take Evista with hormonal birth control?
It is not recommended to take Evista with hormonal birth control. Talk to your doctor about other options for birth control while taking Evista.
Will Evista lower my blood pressure?
Evista may help to lower high blood pressure in some people. However, it is not approved for this use. Talk to your doctor about other medications that may help to lower your blood pressure.
Does Evista affect cholesterol levels?
Yes, Evista can affect cholesterol levels. Studies have found that it can help to reduce levels of bad cholesterol (LDL) and increase levels of good cholesterol (HDL). Talk to your doctor about other medications that may help to lower your cholesterol.
Does Evista help with mood changes?
Evista may help to reduce tension, irritability, and fatigue in some people. However, it is not approved for this use. Talk to your doctor about other medications that may help with mood changes.
Can I take Evista with other medications?
Yes, you can take Evista with other medications. However, certain medications may interact with Evista, including certain antibiotics, birth control pills and anticoagulants. Be sure to tell your doctor about any other medications you are taking before taking Evista.
If I take Evista, will I need to have regular checkups?
Yes, it is recommended that you have regular checkups while taking Evista. Your doctor may recommend that you have a complete blood count (CBC) and some liver tests before and during treatment with Evista.
Can I take Evista if I'm breastfeeding?
No, it is not recommended to take Evista while breastfeeding. It is not known if the drug passes into breast milk and could potentially harm a nursing infant. Talk to your doctor about the best options for you.
Does Evista cause any withdrawal symptoms?
No, Evista does not usually cause any withdrawal symptoms when you stop taking it. However, some people may experience a return of some of the symptoms they were taking Evista to treat, such as hot flashes or joint pain. Talk to your doctor about any withdrawal symptoms you experience.
If I stop taking Evista, how soon will I start to feel better?
It may take some time to start feeling better after you stop taking Evista. Some people may start to feel better within a few days, while others may take longer. Talk to your doctor if you experience any withdrawal symptoms or if your symptoms do not improve.