Estora
Estora Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Estora is a brand name. Its generic name is Eszopiclone.
Estora Introduction
Estora (brand name Lunesta) is a nonbenzodiazepine hypnotic agent that is typically used to treat insomnia. It works to induce sleep by affecting certain brain chemicals in the body that are related to sleep. Estora is only intended for short-term use, as it can cause tolerance and dependence.
Uses For Estora
Estora is commonly prescribed for the treatment of insomnia. Common symptoms of insomnia include difficulty falling asleep, frequently waking up during the night, and not feeling well-rested upon waking up. Estora can help to mitigate these symptoms by helping to induce sleep faster and staying asleep longer.
Mechanism of Action
Estora works by binding to GABA-A receptors in the brain and is believed to interact with the neurotransmitter gamma-aminobutyric acid (GABA). This binding to the GABA-A receptors helps to reduce the amount of neuronal activity in the brain and as a result can induce sleep.
How Long Does It Take to Work?
Estora typically begins to work within 30-60 minutes after ingesting the medication.
Absorption
Estora is rapidly and completely absorbed into the bloodstream. Peak levels are reached within an hour to an hour and a half after taking the medication.
Route of Elimination
Estora is eliminated primarily via the kidneys and also in small amounts through the feces through bile acid conjugation.
Dosage
Estora is available as a tablet to be taken orally and comes in dosages of 1 mg, 2 mg, and 3 mg. The recommended starting dose is 2 mg and should not exceed more than 3 mg in a single dose. Lower doses are recommended for elderly patients or those with liver impairment.
Administration
Estora should be taken at bedtime as it can cause drowsiness. The medication should not be taken if activities requiring alertness such as driving, or operating machinery are required.
Side Effect
Common side effects associated with Estora include drowsiness, dizziness, lightheadedness, headache, diarrhea, dry mouth, and unusual dreams.
Toxicity
Estora has a low toxicity profile and the most common side effects are usually minor. Overdose symptoms can include confusion, slow breathing, and loss of consciousness.
Precaution
Estora can cause drowsiness and it is important to use caution when taking the medication if engaging in activities that require alertness, such as driving. Patients should also avoid alcohol while taking Estora as this may increase the side effects.
Interaction
Estora may interact with a number of medications, including sedatives, benzodiazepines, antifungals, birth control pills, and certain antibiotics. Patients should inform their doctor of any other medications they are taking prior to taking Estora.
Disease Interaction
Estora may interact with a number of diseases whereby the symptoms of the disease may be worsened when taking the medication. Diseases such as COPD, depression, kidney disease, liver disease, as well as certain mental health disorders should be discussed with the doctor prior to taking the medication.
Drug Interaction
Estora may interact with certain drugs and may increase the effects of other medications, such as opioids, benzodiazepines, and various other central nervous system depressants. Patients should inform their doctor of any drugs they are taking prior to taking Estora.
Food Interactions
Estora may interact with certain foods and patients should avoid taking it with grapefruit or grapefruit juice.
Pregnancy Use
Estora is contraindicated during pregnancy, as it can cause significant harm to the fetus. Therefore, women who are pregnant or planning to become pregnant should avoid taking Estora.
Lactation Use
Estora is not recommended for use during breastfeeding due to the potential risk to the infant.
Acute Overdose
Acute overdose of Estora can be life threatening and patients should seek immediate medical attention if an overdose is suspected. Symptoms of an overdose may include confusion, coma, slurred speech, and loss of consciousness.
Contraindication
Estora is contraindicated for anyone with a known hypersensitivity to the drug. It is also not recommended for anyone with severe respiratory depression or a history of substance abuse. Patients with renal or hepatic impairment should exercise caution when taking the drug.
Use Direction
Estora should be taken as directed by the patient's doctor and should be taken at bedtime. The tablet should be swallowed whole and not broken or dissolved. The dosage for the medication should also be discussed with the doctor prior to taking the medication.
Storage Condition
Estora should be stored at room temperature in a dry place. It should also be kept out of the reach of children and pets.
Volume of Distribution
Estora has a volume of distribution of about 0.3 L/kg.
Half Life
Estora has an elimination half-life of 6-12 hours in healthy adults.
Clearance
Estora has a renal clearance of 0.3 L/h/kg.
Here you find in details version of Estora
Some Frequently Asked Questions About Estora
What is Estora?
Estora is a prescription medication used to help people with insomnia fall asleep. It is a type of sleep medication that belongs to the class of drugs known as sedative-hypnotics.
How does Estora work?
Estora works by slowing down brain activity and calming the body. It helps people to fall asleep more quickly and stay asleep longer.
Who should not use Estora?
Estora should not be used by anyone under age 18, or by anyone who is alcohol dependent. It should also not be used by people who have a history of substance abuse or addiction.
Is Estora habit-forming?
Yes, Estora is habit-forming and can lead to physical and psychological addiction if not taken as prescribed. It is important to talk with your doctor about how to take Estora safely and correctly.
What are the side effects of Estora?
Common side effects of Estora include drowsiness, dizziness, headache, and nausea. Less common side effects include difficulty breathing, confusion, anxiety, and rapid heartbeat. If you experience any of these side effects, contact your doctor immediately.
Will Estora make me gain weight?
It is possible that Estora could lead to weight gain due to increased appetite. Talk to your doctor if you're concerned about your weight while using Estora.
Does Estora cause memory loss?
Estora has been known to cause memory loss, particularly in people taking it for extended periods of time. Talk to your doctor if you are concerned about memory loss when taking Estora.
Do I need a prescription for Estora?
Yes, Estora is a prescription medication and you will need a doctor’s prescription before you are able to purchase it.
Can I buy Estora over-the-counter?
No, Estora is only available with a prescription from your doctor.
Can I take Estora with alcohol?
It is not recommended to take Estora with alcohol. Alcohol can worsen the side effects of Estora, such as drowsiness and dizziness, and may put you at risk for more serious side effects.
Can I take Estora while pregnant?
It is not recommended to take Estora while pregnant, as it may cause harm to the unborn baby. Talk to your doctor about the risks and benefits of taking Estora.
Can I take Estora while breastfeeding?
It is not recommended to take Estora while breastfeeding, as it can pass into breast milk and may cause harm to the nursing baby. Talk to your doctor about the best treatment option for you.
How long does Estora last?
The effects of Estora usually last for up to 8 hours, depending on the dosage taken.
What should I do if I miss a dose of Estora?
If you miss a dose of Estora, you should take it as soon as you can. However, if it is almost time for your next dose, skip the missed dose and take your regular dose at the usual time.
How should I store Estora?
Estora should be stored at room temperature and should be kept away from moisture and heat. Keep the medication out of reach of children and pets.
Is Estora addictive?
Estora is a habit-forming drug that can lead to physical and psychological dependence. It is important to follow your doctor’s instructions when taking Estora.
What are the possible drug interactions of Estora?
Estora can interact with certain medications, such as antihistamines, sleep medications, and anti-anxiety medications. It is important to tell your doctor about all the medications you are taking before taking Estora.
What are the withdrawal symptoms of Estora?
Common withdrawal symptoms of Estora include insomnia, irritability, anxiety, nausea, headaches and stomach discomfort. You should talk to your doctor before stopping Estora, as they can provide a plan to slowly reduce your dosage.
What is the recommended dosage of Estora?
The dosage of Estora typically ranges from 1 mg to 3 mg. It is important to follow your doctor’s instructions and take the lowest effective dose.
Can Estora cause nightmares?
Estora can cause nightmares in some people. Talk to your doctor if you are experiencing nightmares while taking Estora.
Is Estora available as a generic drug?
Yes, Estora is available as a generic drug.
How long does it take for Estora to kick in?
It typically takes 30 to 60 minutes for Estora to start working.
What are the long-term effects of Estora?
Common long-term effects of Estora include confusion, memory loss, drowsiness, and sedation. If you experience any of these effects, you should contact your doctor.
What are the short-term effects of Estora?
Common short-term effects of Estora include drowsiness, dizziness, headache, nausea, and difficulty concentrating.
What is the drug classification of Estora?
Estora belongs to the class of drugs known as sedative-hypnotics.
Can Estora make me sleepy during the day?
Yes, Estora can make you sleepy during the day. It is important to take it exactly as prescribed and avoid taking it too close to your desired wake-up time.
Can I take Estora and other sleep medications together?
No, you should not take Estora and other sleep medications at the same time, as this can cause serious side effects. Talk to your doctor if you need to take multiple sleep medications.
Can I take Estora with antidepressants?
Estora can interact with certain antidepressants, so it is important to tell your doctor about all of the medications you are taking before taking Estora. Your doctor will be able to determine if it is safe to take Estora with your current medications.
Can Estora cause anxiety?
Estora can cause anxiety in some people. Talk to your doctor if you experience anxiety after taking Estora.
What are the benefits of taking Estora?
Estora can help people with insomnia fall asleep quicker and stay asleep longer. This can ultimately lead to increased concentration and productivity during the day, as well as improved overall quality of life.
Can Estora be used for long-term treatment of insomnia?
Estora is not recommended for long-term treatment of insomnia, as it can lead to physical and psychological dependence. Talk to your doctor about the best treatment option for you.
Can I take Estora if I have liver disease?
Estora can be dangerous for people with liver disease. Talk to your doctor if you have any liver issues before taking Estora.
Does Estora cause constipation?
Estora can cause constipation in some people. Talk to your doctor if you experience constipation while taking Estora.
Is Estora safe for long-term use?
Estora is not recommended for long-term use due to the risk of physical and psychological dependence. Talk to your doctor about the best treatment option for you.
Can I take Estora if I am pregnant or breastfeeding?
It is not recommended to take Estora if you are pregnant or breastfeeding, as it can cause harm to the unborn baby. Talk to your doctor about the risks and benefits of taking Estora.
Can I take over-the-counter medications with Estora?
Yes, some over-the-counter medications are safe to take with Estora, such as pain relievers or decongestants. It is important to talk to your doctor or pharmacist before taking any over-the-counter medications with Estora.
Can I drive while taking Estora?
Estora can cause drowsiness and impaired mental and physical abilities. It is not recommended to drive or operate heavy machinery while taking Estora.
What is the best way to take Estora?
It is important to take Estora exactly as prescribed by your doctor. Take the lowest effective dose and do not take it too close to your desired wake-up time.
Can I take Estora if I have a history of substance abuse?
Estora is not recommended if you have a history of substance abuse or addiction. Talk to your doctor about the safest treatment option for you.
How does Estora differ from other sleep medications?
Estora is a member of the sedative-hypnotic class of drugs, which means that it works by slowing down brain activity and calming the body. Other sleep medications, such as benzodiazepines, have different mechanisms of action and can be prescribed for different types of insomnia.