Enoxacin

Enoxacin Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Enoxacin is a brand name. Its generic name is Enoxacin.

Enoxacin

Enoxacin is a synthetic fluoroquinolone antibiotic used to treat a variety of bacterial infections.It is typically used to treat infections of the chest, urinary tract, skin, and joints.

Uses

Enoxacin is typically used to treat infections of the chest, urinary tract, skin, and joints, however, it can also be used to treat various other bacterial infections.

Mechanism of Action

Enoxacin inhibits bacterial DNA gyrase, an enzyme that is essential for DNA replication. By inhibiting this enzyme, enoxacin prevents bacterial DNA replication, thereby stopping bacterial growth.

How Long Does It Take To Work?

Enoxacin typically begins to work within 24 hours, however, it may take longer for certain infections.

Absorption

Enoxacin is readily absorbed from the gastrointestinal tract, achieving peak concentrations in the blood within 1 to 3 hours.

Route of Elimination

Enoxacin is primarily eliminated in the urine via the kidney. About 75-90% of a dose is excreted unchanged in the urine.

Dosage

The usual adult dosage is 400 mg twice daily for mild to moderate urinary tract infections. For severe infections, a dosage of 400 mg three times daily is recommended. For pediatric use, the usual dosage is 10 mg/kg body weight or 15-25 mg/kg/d divided into two doses. The dose should not exceed 400 mg per day.

Administration

Enoxacin should be taken orally with a full glass of water. The capsules should be swallowed whole and not crushed or chewed.

Side Effects

Common side effects include nausea, vomiting, diarrhea, abdominal pain, headache, and dizziness. Serious side effects may include allergic reactions, liver damage, central nervous system reactions, increased sensitivity of the skin to sunlight, and tendon damage.

Toxicity

Enoxacin is generally considered safe and well-tolerated. Overdose may cause nausea, vomiting, diarrhea, abdominal cramps, hallucinations, and dizziness. In case of overdose, general supportive measures should be taken and the patient should be monitored closely.

Precautions

• Enoxacin should be used with caution in pregnant and breastfeeding women.
• Enoxacin should be used with caution in patients with a history of liver or kidney disease.
• Enoxacin should be used with caution in patients with a history of epilepsy or a history of psychiatric disorders.
• Enoxacin should be used with caution in patients being treated with other drugs that may interact with enoxacin.

Interactions

Enoxacin has the potential to interact with a variety of drugs, including antacids, cimetidine, antidiabetic drugs, theophylline, and warfarin. Concomitant use of these drugs should be avoided or monitored closely.

Disease Interaction

Enoxacin may be contraindicated in patients with a history of liver or kidney disease and those with a history of epilepsy or other neurological disorders.

Drug Interaction

Enoxacin has the potential to interact with a variety of drugs, including antacids, cimetidine, antidiabetic drugs, theophylline, and warfarin. Concomitant use of these drugs should be avoided or monitored closely.

Food Interactions

Enoxacin should be taken a least two hours before or after meals. Grapefruit juice should be avoided as it may increase the risk of adverse effects.

Pregnancy Use

Enoxacin should be used with caution in pregnant women as it has potential risks. Women should notify their doctor if they are pregnant or breastfeeding before taking this medication.

Lactation Use

Enoxacin should be used with caution in breastfeeding women as it has potential risks. Women should notify their doctor if they are pregnant or breastfeeding before taking this medication.

Acute Overdose

In case of an acute overdose, general supportive measures should be taken and the patient should be monitored closely.

Contraindication

Enoxacin is contraindicated in patients with a known hypersensitivity to quinolone antibiotics.

Use Direction

Enoxacin should be taken orally twice daily with a full glass of water one hour before or two hours after meals. The capsules should be swallowed whole and not crushed or chewed.

Storage Condition

Enoxacin should be stored at room temperature between 15-30°C (59-86°F). It should be kept away from light, moisture and heat.

Volume of Distribution

Enoxacin has an average volume of distribution of about 2.2 liters/kg.

Half Life

Enoxacin has an elimination half-life of 4-9 hours.

Clearance

Enoxacin has an average clearance of 0.2 liters/hour/kg.

Here you find in details version of Enoxacin

Some Frequently Asked Questions About Enoxacin

What is enoxacin?

Enoxacin is an antibiotic medication used to treat certain types of infections caused by bacteria. It is used to treat bacterial infections of the bladder, prostate, stomach, intestines, skin, and respiratory tract. The drug is also sometimes used to prevent opportunistic infections in people with HIV.

What is the brand name of enoxacin?

The brand name of enoxacin is Penetrex.

What types of bacteria does enoxacin fight?

Enoxacin is used to fight certain types of bacteria including Escherichia coli, Klebsiella pneumoniae, Proteus mirabilis, Salmonella, Shigella, and Staphylococcus.

How should enoxacin be taken?

Enoxacin can be taken orally or intravenously. The usual dose is 200 mg taken four times daily for 7 to 10 days. It is important to take enoxacin exactly as prescribed by your doctor.

What should I do if I miss a dose of enoxacin?

If you miss a dose of enoxacin, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and take your next dose at the usual time. Do not take two doses at the same time.

What should I avoid while taking enoxacin?

Avoid alcohol while taking enoxacin. Alcohol may increase the side effects of enoxacin. It is also important to avoid taking any other medications unless your doctor has approved them.

What are the possible side effects of enoxacin?

The most common side effects associated with enoxacin are nausea, vomiting, diarrhea, abdominal pain, headache, and rash. Serious but rare side effects include anaphylaxis, Stevens-Johnson syndrome, and hepatitis. If you experience any of these symptoms, call your doctor immediately.

Is enoxacin safe for pregnant women?

The safety of enoxacin during pregnancy has not been established. If you are pregnant, it is important to tell your doctor before taking enoxacin.

Can I take enoxacin with other medications?

Before taking any medication with enoxacin, tell your doctor. Certain medications may interact with enoxacin, including blood thinners, antifungals, insulin, and face medicines.

Is enoxacin safe to take with alcohol?

No. Enoxacin should not be taken with alcohol due to its potential to increase the risk of side effects.

Can I take enoxacin if I have allergies?

It is important to tell your doctor if you have any allergies before starting enoxacin. Enoxacin may contain inactive ingredients that can cause an allergic reaction.

Can I give enoxacin to children?

Enoxacin is not recommended for use in children under 12 years of age. Before giving enoxacin to a child, it is important to talk to your doctor.

What should I do if I experience an allergic reaction to enoxacin?

If you experience an allergic reaction to enoxacin, stop taking the medication and contact your doctor immediately.

How long does it take for enoxacin to work?

It usually takes several days for enoxacin to start working. It is important to take the drug exactly as prescribed by your doctor.

Is enoxacin available in generic form?

Yes. Enoxacin is available in generic form.

What is the cost of enoxacin?

The cost of enoxacin varies depending on the brand and the pharmacy. It is typically covered by most insurance plans.

Are there any interactions with other drugs?

Yes. Enoxacin can interact with other drugs, including blood thinners, antifungals, insulin, and certain antibiotics. It is important to tell our doctor about all medications you are taking before starting enoxacin.

Does enoxacin have any special storage requirements?

Yes. Enoxacin should be stored at room temperature and away from direct light. It should also be kept in its original container with the tight-fitting lid.

What should I do if I have taken an overdose of enoxacin?

If you think you have taken an overdose of enoxacin, contact your doctor or poison control center right away. It is important to seek medical attention as soon as possible to prevent serious complications.

Can I take enoxacin with food or milk?

Yes. It is typically recommended to take enoxacin with food or with a glass of milk. Taking the drug with food can help prevent stomach upset.

How long will enoxacin remain in my system?

Enoxacin will typically remain in your system for up to 72 hours after the last dose. The amount of time the drug remains in your system may vary depending on your individual metabolism.

Can I donate blood while taking enoxacin?

No. You should not donate blood while taking enoxacin or for at least one month after the last dose.

Can I drink alcohol while taking enoxacin?

No. It is not advised to drink alcohol while taking enoxacin due to its potential to worsen side effects.

How is enoxacin metabolized in the body?

Enoxacin is metabolized mainly by the liver. Metabolites of the drug are eliminated mainly through urinary excretion.

Should I take enoxacin with a full glass of water?

Yes. It is important to take enoxacin with a full glass of water to help prevent nausea and other side effects.

Is enoxacin safe for breastfeeding women?

It is not advised to take enoxacin while breastfeeding. If you are breastfeeding, it is important to talk to your doctor before taking this medication.

Can elderly people take enoxacin?

Yes. However, elderly people are more likely to experience side effects from enoxacin. It is important to monitor elderly people closely while taking this medication.

Is enoxacin excreted through breast milk?

Yes. Enoxacin is excreted in breast milk, although in small quantities. If you are breastfeeding, it is important to talk to your doctor before taking enoxacin.

What is the half-life of enoxacin?

The half-life of enoxacin is approximately 4 hours.

Can enoxacin be used to treat viral infections?

No. Enoxacin is an antibiotic and is only effective in treating bacterial infections.

Can enoxacin cause dizziness?

Yes. Dizziness is a possible side effect of enoxacin. If you experience this side effect, stop taking enoxacin and contact your doctor immediately.

Can I take antacids while taking enoxacin?

You should not take antacids within 2 hours of taking enoxacin due to its potential to reduce the effectiveness of enoxacin.

What is the maximum dosage of enoxacin?

The maximum dosage of enoxacin is 800 mg per day.

Can enoxacin cause nausea?

Yes. Nausea is a common side effect of enoxacin. If you experience nausea, talk to your doctor about ways to manage the side effect.

Is enoxacin safe for people with kidney disease?

People with kidney disease should talk to their doctor before taking enoxacin. The medication may need to be taken at a lower dose or in smaller doses.

Can enoxacin cause a yeast infection?

Yes. Taking enoxacin can increase your risk of developing a yeast infection. Talk to your doctor if you experience any symptoms of a yeast infection while taking enoxacin.

How long can I take enoxacin?

The length of treatment with enoxacin depends on the type and severity of the infection. Generally, enoxacin is taken for 7 to 10 days.

Are there any natural alternatives to enoxacin?

No. Enoxacin is a prescription medication and there are no approved natural alternatives to the drug.

Can I stop taking enoxacin if I feel better?

No. It is important to take enoxacin for the entire duration prescribed by your doctor. Stopping the medication early may cause the infection to come back or worsen.

Is enoxacin safe for people with liver disease?

People with liver disease should talk to their doctor before taking enoxacin. The doctor may need to adjust the dose or frequency of the drug depending on the severity of the liver disease.

Can enoxacin cause drowsiness?

Yes. Drowsiness is a possible side effect of enoxacin. Avoid performing activities that require alertness until you are sure that the drug does not affect you.