Endomal

Endomal Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Endomal is a brand name. Its generic name is Artemotil.

Endomal: Introduction

Endomal (generic name: bromfenac sodium) is a nonsteroidal anti-inflammatory drug (NSAID) used for the treatment of acute, chronic, and postoperative pain. It is commonly prescribed for the relief of back pain, shoulder pain, and knee pain.

Uses for Endomal

Endomal is used for the symptomatic relief of postoperative pain, chronic musculoskeletal pain, and cervical pain. It is also used for the relief of inflammation and swelling resulting from injury or disease.

Mechanism of Action

Endomal works by blocking the production of prostaglandins, hormone-like substances that can cause inflammation and pain. It works by inhibiting the action of cyclooxygenase (COX-1 & COX-2) enzymes, which catalyze the production of prostaglandins. Inhibiting these enzymes prevents the production of prostaglandins, thus reducing pain and inflammation.

How Long Does it Take to Work?

The maximum effect of Endomal is usually observed within 2-3 hours after administration, and the drug should start to take effect within 30 minutes of administration.

Absorption

Endomal is rapidly absorbed after oral administration and is well absorbed from the gastrointestinal tract. The peak plasma concentration is reached 1.5 to 3 hours after administration. The bioavailability of the drug is around 60%.

Route of Elimination

Endomal is eliminated from the body primarily by the kidneys. Approximately 40-50% of the administered dose is eliminated by the kidneys as unchanged drug or metabolites.

Dosage

The recommended dose of Endomal for adults is 10mg per day. It can be taken with or without food. Patients with renal impairment should take half the dose. Patients with liver impairment should not take the drug. Patients should not take more than the recommended dose.

Administration

Endomal should be taken orally once per day, preferably at the same time each day. It can be taken with or without food.

Side Effects

Common side effects of Endomal include headache, stomach pain, diarrhea, nausea, vomiting, and constipation. Serious side effects include rash, itching, painful urination, and difficulty breathing.

Toxicity

The toxic dose of Endomal has not been well established, and overdoses should be avoided. Symptoms of overdose include nausea, vomiting, abdominal pain, dizziness, and tachycardia.

Precautions

Patients should not take Endomal if they have a history of hypersensitivity to bromfenac or any other nonsteroidal anti-inflammatory drugs (NSAIDs). Patients with history of asthma, active peptic ulcer, bleeding problems, heart failure, and kidney or hepatic impairment should talk to their doctor before taking Endomal. Endomal should not be taken in combination with certain drugs, including other NSAIDs, corticosteroids, and anticoagulants.

Interactions

Endomal may interact with other drugs, including anticoagulants, corticosteroids, other NSAIDs, diuretics, lithium, and cyclosporine. These interactions can increase the risk of side-effects or decrease the effectiveness of the drug.

Disease Interaction

Patients with bleeding disorders, asthma, heart failure, and renal or hepatic impairment should talk to their doctor before taking Endomal.

Drug Interaction

Endomal should not be taken in combination with certain drugs, including other NSAIDs, corticosteroids, and anticoagulants. The drug should also not be taken in combination with alcohol.

Food Interactions

Food should be avoided while taking Endomal as it may reduce its absorption.

Pregnancy Use

The safety of Endomal in pregnant women has not been established; pregnant women should not take the drug unless it is absolutely necessary.

Lactation Use

The safety of Endomal during lactation has not been established; lactating women should not take the drug unless it is absolutely necessary.

Acute Overdose

Symptoms of overdose include nausea, vomiting, abdominal pain, dizziness, and tachycardia. Treatment of an overdose should be supportive and symptomatic.

Contraindication

Endomal is contraindicated in patients with a history of hypersensitivity to bromfenac or any other nonsteroidal anti-inflammatory drugs (NSAIDs).

Use Direction

Endomal should be taken orally once per day, preferably at the same time each day. It can be taken with or without food.

Storage Condition

Endomal should be stored at room temperature and away from direct sunlight. The tablets should be protected from moisture.

Volume of Distribution

The volume of distribution of Endomal is not known.

Half Life

The elimination half-life of Endomal is 6-12 hours.

Clearance

The clearance of Endomal is not known.

Here you find in details version of Endomal

Some Frequently Asked Questions About Endomal

What is Endomal?

Endomal is a branded prescription drug approved by the FDA for the treatment of early-onset migraine attack.

What are the ingredients in Endomal?

The active ingredient in Endomal is rizatriptan benzoate. It is also formulated with lactose monohydrate, magnesium stearate, hypromellose, microcrystalline cellulose, sodium starch glycolate and titanium dioxide.

How long does it take for Endomal to start working?

Endomal typically begins to work within 30 minutes of taking the dose.

What is the recommended dosage of Endomal?

The recommended dose of Endomal is 10 mg orally when needed for the treatment of a migraine attack, with a maximum dose of 30 mg per day.

What are the possible side effects of taking Endomal?

Common side effects with Endomal include nausea, dizziness, hallusination, and drowsiness.

Can Endomal be taken with other medications?

It is important to discuss all medications and supplements taken with your doctor before taking Endomal to reduce the risk of any drug interactions.

How many times a day should I take Endomal?

The recommended dose for Endomal is to take it as needed for the treatment of a migraine attack, with a maximum dose of 30 mg per day.

What is the generic name of Endomal?

The generic name of Endomal is Rizatriptan Benzoate.

Does Endomal cause weight loss?

No, Endomal does not cause weight loss.

Can Endomal be taken while pregnant?

It is not recommended to take Endomal while pregnant, unless it has been prescribed by a doctor.

Are there any long-term side effects associated with Endomal?

Long-term side effects of Endomal are rare, but serious side effects can occur including stroke, heart attack, liver problems, and increased blood pressure.

Can Endomal be taken with food?

Yes, Endomal can be taken with food or without food. It is important to take the medication as prescribed by your doctor.

What should I do if I miss a dose of Endomal?

It is important not to take a double dose of Endomal if you miss a dose. Contact your doctor or pharmacist if you have any questions about the missed dose.

Can I take Endomal with alcohol?

It is not recommended to take alcohol while taking Endomal. Alcohol can increase the risk of side effects and may cause your migraine to worsen.

Is Endomal available as a generic?

No, Endomal is not currently available as a generic.

Is Endomal covered by insurance?

Yes, some insurance plans may cover the cost of Endomal. Check with your insurance provider for specific coverage and eligibility.

Do I need a prescription for Endomal?

Yes, Endomal is only available with a valid prescription from a doctor.

What is the most common form of Endomal used?

The most common form of Endomal used is orally-dissolving tablets.

Does Endomal cause drowsiness?

Yes, drowsiness is a common side effect of Endomal. It is important to avoid driving or operating heavy machinery when taking Endomal.

What is the shelf life of Endomal?

The shelf life of Endomal tablets is 2 years. It is important to keep the medication in a cool, dry place and away from children.

How long does Endomal stay in my system?

The effects of Endomal typically last up to 6 hours but can remain in your system for up to 48 hours.

Can I take Endomal while breastfeeding?

It is not recommended to take Endomal while breastfeeding. Consult with your doctor for more information.

What are the most common reasons people take Endomal?

The most common reason people take Endomal is for the symptomatic treatment of migraine headaches.

What is the recommended dose of Endomal for adults?

The recommended dose for adults is 10 mg orally when needed for the treatment of a migraine attack, with a maximum dose of 30 mg per day.

Can I take Endomal if I have high blood pressure?

It is important to speak with your doctor before taking Endomal if you have high blood pressure or any other heart condition.

Can I take Endomal if I am taking other migraine medications?

It is important to discuss all medications and supplements taken with your doctor before taking Endomal to reduce the risk of any drug interactions.

How much does Endomal cost?

The cost of Endomal depends on the amount prescribed and the pharmacy. Check with your local pharmacy for more information about the cost of Endomal.

Are there side effects associated with taking too much Endomal?

Taking too much Endomal can lead to serious side effects such as difficulty breathing, irregular heart rate, seizure, and coma.

Can Endomal be taken with other migraine medications?

It is important to discuss all medications and supplements taken with your doctor before taking Endomal to reduce the risk of any drug interactions.

Does Endomal cause nausea?

Yes, nausea is a common side effect of Endomal. If you experience excessive nausea, it is important to contact your doctor.

Does Endomal need to be taken with food?

Endomal can be taken with food or without food. It is important to take the medication as prescribed by your doctor.

Is Endomal covered by Medicare?

Your Medicare coverage for Endomal will depend on your Medicare plan. Check with your Medicare plan for specific coverage and eligibility.

Can I take Endomal while on blood thinners?

It is important to discuss all medications and supplements taken with your doctor before taking Endomal to reduce the risk of any drug interactions.

Is Endomal a muscle relaxant?

No, Endomal is not a muscle relaxant. It is used to treat the symptoms of migraine headaches.

Are there any interactions between Endomal and blood pressure medications?

It is important to discuss all medications and supplements taken with your doctor before taking Endomal to reduce the risk of any drug interactions.

Age does Endomal start to work?

Endomal typically begins to work within 30 minutes of taking the dose.

Can I take Endomal if I have kidney disease?

It is important to speak with your doctor before taking Endomal if you have kidney disease or any other medical condition.

Can Endomal be used to prevent migraine attacks?

No, Endomal is not designed to prevent migraine attacks. It is used to treat the symptoms of migraine headaches.

What are the most common side effects of taking Endomal?

Common side effects with Endomal include nausea, dizziness, hallucinations, and drowsiness.

Is Endomal safe for children?

Endomal is not recommended for children younger than 18 years of age. Consult with your doctor before giving Endomal to a child.

Is Endomal safe for seniors?

It is important to speak with your doctor before taking Endomal if you are a senior, as it is not recommended for anyone older than 75 years of age.

What are the contraindications of taking Endomal?

The contraindications of taking Endomal include any allergic reaction to the drug, a history of stroke or transient ischemic attack, uncontrolled high blood pressure, and severe liver disease.

Can Endomal cause an increase in blood pressure?

Yes, an increase in blood pressure is a possible side effect of taking Endomal. It is important to monitor your blood pressure regularly while taking Endomal to reduce the risk of serious side effects.