Eflornithine

Eflornithine Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Eflornithine is a brand name. Its generic name is Eflornithine.

Eflornithine

Eflornithine is a medication used to reduce growth of unwanted facial and body hair in women. It blocks a natural substance called ornithine decarboxylase, which stimulates hair growth in certain areas of the body.

Uses For

The primary use of eflornithine is to reduce the growth of unwanted facial hair in women. It is used as a topical cream that is spread onto the areas where extra hair is growing.

Mechanism Of Action

Eflornithine works by blocking the action of a natural substance called ornithine decarboxylase, which is responsible for stimulating hair growth in certain areas of the body. Without this substance, the hair growth will be slower or stopped entirely.

How Long Does It Take To Work?

It typically takes 3-4 weeks for eflornithine to start working. Results may vary from person to person.

Absorption

Eflornithine is absorbed through the skin when applied topically. It reaches its highest blood concentrations in 2-3 hours following application.

Route Of Elimination

Eflornithine is broken down in the liver and then eliminated in the urine.

Dosage

Eflornithine is available as a 2% topical cream. The dose is 2-4 mg per cm2 of the affected area. Apply the cream once daily to the affected area.

Administration

Eflornithine is typically applied twice a day to the affected area, or as directed by your doctor. It should not be applied to broken, infected, or bleeding skin.

Side Effects

The most common side effects of eflornithine are burning, itching, and redness of the skin at the site of application. Other side effects include acne, rash, and hives.

Toxicity

When eflornithine is used as directed, it is generally well-tolerated. However, if ingested in large amounts, it may cause serious adverse reactions including seizures, coma, and death.

Precaution

Eflornithine should be used with caution in patients with a history of allergies, kidney or liver problems, or mental disorders. It should not be used on the face, neck, or genital areas, and should only be used as directed.

Interaction

Eflornithine may interact with other medications, herbs, and supplements. Before using it, inform your healthcare provider of all other medications, herbs, and supplements that you are taking.

Disease Interaction

Eflornithine may interact with certain diseases, such as kidney, liver, and mental disorders. Let your healthcare provider know if you have any of these conditions before using this medication.

Drug Interaction

Eflornithine may interact with certain drugs, so inform your doctor of any medications, herbs, and supplements that you are taking before starting this medication.

Food Interactions

Eflornithine is not known to interact with food. However, it is important to follow the directions on the medication’s label and talk to your doctor about any potential food interactions.

Pregnancy Use

Eflornithine is not recommended for use during pregnancy. It should be avoided except in cases of life-threatening conditions for which alternate treatments are not available.

Lactation Use

Eflornithine is not recommended for use while breastfeeding. The intervention of a health care provider is advised to determine if it is safe to use during this period.

Acute Overdose

If an overdose of eflornithine is suspected, seek emergency medical attention. Symptoms of an overdose may include seizures, coma, and death.

Contraindication

Eflornithine is contraindicated in patients with a known hypersensitivity to the active ingredient or any of the excipients contained in the product. It should not be used on the face, neck, or genital areas.

Use Direction

Eflornithine should be applied twice a day or as directed by your doctor. It should be used on clean, dry skin, avoiding broken, infected, or bleeding areas. Wash your hands before and after use.

Storage Condition

Eflornithine should be stored at room temperature in a cool, dry place. Keep it out of reach of children and pets.

Volume Of Distribution

The volume of distribution of eflornithine is not known.

Half Life

The half-life of eflornithine is not known.

Clearance

The clearance of eflornithine is not known.

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