Dulfre

Dulfre Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Dulfre is a brand name. Its generic name is Bisacodyl.

Dulfre Introduction

Dulfre is an over-the-counter laxative medication that helps to relieve constipation and treat hard, dry stools. It is available in tablet, suppository, and enema form. Dulfre can also be given intravenously and orally to treat fecal impaction. Dulfre is used for a variety of clinical situations, such as to promote bowel movement, relieve constipation, cleanse the bowel before a procedure,or to promote defecation in patients who cannot take oral medications. Dulfre is an anthraquinone derivative.

Uses for

Dulfre is used for a variety of conditions, including constipation, preparing the bowel for a medical procedure, and fecal impaction. Dulfre is also used to cleanse the bowel before a procedure.

Mechanism of Action

Dulfre works by irritating the lining of the large intestine, which results in the intestines contracting more frequently and with greater force, leading to increased peristalsis, the movement of the intestines to help move the stool out of the body. Dulfre has both a direct and indirect effect on the large intestine, which helps increase the movement of the intestines.

How Long Does it Take to Work

Dulfre is usually effective within 12 to 72 hours of taking the medication. When taken orally, most people will typically have results within 6 to 12 hours.

Absorption

Dulfre is rapidly absorbed after administration and has an onset of action of 1 to 6 hours. Oral bisacodyl is completely absorbed within 2 to 4 hours after taking.

Route of Elimination

Dulfre is eliminated from the body through the feces, in mostly unaltered form.

Dosage

For adults, the usual dosage of bisacodyl is 5 to 15 mg taken by mouth once or twice a day. For children and young adults, the dosage may range from 5 to 10 mg daily. For constipation in adults, the suggested dosage is usually 10 mg taken orally 1 to 3 times daily. For constipation in children younger than 12 years of age, the suggested dosage is 5 mg taken once or twice a day.

Administration

Dulfre is available as both a tablet and as a suppository. The tablets can be swallowed, taken with liquid, or chewed. The suppositories should be inserted rectally, where they dissolve and are rapidly absorbed. The suppository is usually used for relieving constipation when taking the medication orally isn't possible.

Side Effect

Common side effects of bisacodyl include cramps, stomach pain, nausea, diarrhea, and rectal discomfort. These side effects are typically mild and usually resolve without medical treatment.

Toxicity

Dulfre has a low risk of causing acute toxicity or adverse reactions; however, it can still cause gastrointestinal symptoms like abdominal pain, nausea, and vomiting.

Precaution

Individuals should not take bisacodyl if they have a history of hypersensitivity to any anthraquinone laxative or to any of bisacodyl’s excipients. Along with this, it is recommended to talk with your doctor first if you are pregnant or breastfeeding as bisacodyl can pass into your breast milk. In addition, bisacodyl is not recommended for children under 2 years old.

Interaction

Individuals should not use bisacodyl together with mineral oil, as this can lead to decreased absorption and effectiveness of bisacodyl. Dulfre can also interact with anticoagulants, antibiotics, analgesics, anti-inflammatories, antacids, diuretics, and anticonvulsants.

Disease Interaction

Dulfre should not be taken by individuals with the following conditions: gastrointestinal obstruction, inflammatory bowel disease, appendicitis, intestinal ulcers, diseased anal canal, rectal surgery, undiagnosed abdominal pain, and Crohn’s disease.

Drug Interaction

Potentially serious drug interactions may occur with bisacodyl and anticoagulants, antibiotics (such as tetracycline), analgesics (such as aspirin), anti-inflammatories (such as ibuprofen), antacids (such as calcium carbonate), diuretics (such as furosemide), and anticonvulsants (such as phenobarbital).

Food Interactions

Dulfre may interact with food and alcohol. Consumption of alcohol can interfere with the absorption of bisacodyl, leading to decreased effectiveness. Not enough is known about the interactions between foods and bisacodyl, and it is recommended to consult with a doctor before taking the medication.

Pregnancy Use

Dulfre is not recommended for use during pregnancy. It is unknown if the drug passes through the fetus, and there is not enough information to determine if the drug poses any risks to the fetus. It is recommended to consult a doctor before taking bisacodyl while pregnant.

Lactation Use

It is not recommended to take bisacodyl while breastfeeding. Dulfre may pass into breast milk and can pose risks to the baby. It is recommended to speak with a doctor before taking bisacodyl while breastfeeding.

Acute Overdose

Symptoms of a bisacodyl overdose may include diarrhea, vomiting, abdominal pain, weakness, confusion, or loss of consciousness. In cases of an overdose, it is important to get medical help immediately.

Contraindication

Dulfre is contraindicated in individuals with gastrointestinal obstruction, inflammatory bowel disease, appendicitis, intestinal ulcers, diseased anal canal, rectal surgery, undiagnosed abdominal pain, and Crohn’s disease.

Use Direction

Dulfre should be taken as directed by the healthcare provider. The tablets or suppositories should be taken orally or inserted rectally, as directed. The tablets should be taken once or twice a day, while the suppositories should be taken twice a day. The dosage and length of treatment should follow the healthcare provider’s instructions.

Storage Condition

Dulfre tablets should be stored at room temperature, away from heat, light, and moisture. Suppositories should be stored in a dry place at room temperature, away from heat and moisture.

Volume of Distribution

The volume of distribution for bisacodyl is 18.7L/kg.

Half Life

The half-life of bisacodyl is 1.3 hours.

Clearance

The clearance of bisacodyl is 3.6 L/h/kg.

Here you find in details version of Dulfre

Some Frequently Asked Questions About Dulfre

What is Dulfre?

Dulfre is a type of medication used to treat constipation. It functions as a stimulant laxative, causing the muscles in your intestines to contract more often, allowing bowel movements to occur more quickly.

What is Dulfre used for?

Dulfre is primarily used to treat constipation. It can also be used to empty the bowels before certain procedures or examinations, such as a colonoscopy.

How long does it take for Dulfre to work?

Dulfre usually starts to work within 6 to 12 hours of taking the medication. Some people may experience relief sooner.

What forms does Dulfre come in?

Dulfre is available in tablet, liquid, and suppository form.

How should Dulfre be taken?

The tablets can be taken with a glass of water orally. The liquid form should be taken orally with a measuring spoon and the suppositories should be inserted rectally. Your doctor or pharmacist can provide you with specific instructions.

What are the side effects of Dulfre?

Common side effects can include stomach pain, cramps, bloating, gas, and diarrhea. If you experience any severe or persistent side effects, contact your doctor.

Can Dulfre be taken everyday?

No, Dulfre should not be taken everyday. It is usually recommended to take it only when you experience constipation.

Is Dulfre safe for children?

Dulfre is not recommended for use in children younger than 6 years old. Children 6 and older can take it if prescribed by their doctor.

Is Dulfre safe for pregnant/nursing women?

It is recommended to consult your doctor before taking Dulfre if you are pregnant or breastfeeding. While it is not known to be harmful, it is always better to be safe.

Who should not take Dulfre?

People with certain medical conditions should not take Dulfre, including those with stomach ulcers, severe dehydration, intestinal blockages, and acute inflammatory bowel disease.

Is Dulfre addictive?

No, Dulfre is not an addictive medication.

Does Dulfre have any interactions with other drugs?

Yes, Dulfre can interact with several drugs such as lithium, methotrexate, amiodarone, and some antibiotics. It’s important to tell your doctor about all medications you’re taking before starting to take Dulfre.

Can Dulfre be taken with food?

Yes, Dulfre can be taken with food or on an empty stomach.

Can Dulfre be taken with antacids (such as Tums)?

No, Dulfre should not be taken with antacids. Dulfre should not be taken within two hours before or after taking an antacid.

How long does it take for Dulfre to be out of the system?

Dulfre is typically taken for only a few days, and it usually takes about three days to be completely out of your system.

What is the dosage of Dulfre?

The typical dosage of Dulfre is 10 to 30 mg per day, usually taken as a single dose at bedtime. The dosage may be adjusted by your doctor depending on your condition and response to the medication.

What should I do if I miss a dose of Dulfre?

If you miss a dose of Dulfre, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and take it at your regular time.

What should I do if I overdose on Dulfre?

If an overdose is suspected, seek medical attention immediately. The symptoms of an overdose can include severe stomach pain, cramps, vomiting, and diarrhea.

Does Dulfre have any side effects for elderly people?

Elderly people may be more sensitive to the side effects of Dulfre. Common side effects can include stomach pain, cramps, bloating, gas, and diarrhea. If you experience any severe or persistent side effects, contact your doctor.

Can Dulfre be taken with other laxatives?

No, Dulfre should not be taken with other laxatives or stool softeners. Talk to your doctor before taking any other medications while taking Dulfre.

Will Dulfre cause me to become dependent or addicted?

No, Dulfre is not an addictive medication, and it should not cause you to become dependent or addicted.

What are the symptoms of a Dulfre overdose?

The symptoms of a Dulfre overdose can include severe stomach pain, cramps, vomiting, and diarrhea. If an overdose is suspected, seek medical attention immediately.

Can Dulfre be used to treat fever?

No, Dulfre is not used to treat fever. It is a stimulant laxative specifically used to treat constipation.

What should I do if I experience abdominal pain after taking Dulfre?

If you experience abdominal pain after taking Dulfre, contact your doctor right away. This could be a sign of an adverse reaction.

Is Dulfre safe for long-term use?

No, Dulfre is not meant for long-term use. It is typically taken for only a few days, and should not exceed two weeks.

Can I take Dulfre while pregnant?

It is recommended to consult your doctor before taking Dulfre if you are pregnant. While it is not known to be harmful, it is always better to be safe.

Are there any special instructions for taking Dulfre?

Your doctor or pharmacist can provide special instructions for taking Dulfre based on your individual needs.

Can Dulfre be taken with other medications?

Yes, Dulfre can safely be taken with other medications. However, it is important to tell your doctor about all medications you’re taking before starting to take Dulfre, as it can interact with certain drugs.

Can Dulfre interact with alcohol?

Yes, alcohol can interact with Dulfre and cause adverse effects. It is best not to drink alcohol while taking Dulfre.

Can Dulfre be taken with vitamins or supplements?

Yes, Dulfre can safely be taken with vitamins and supplements. However, it is important to consult your doctor to make sure there are no interactions between Dulfre and any of your vitamins or supplements.

Is Dulfre an over-the-counter medication?

No, Dulfre is a prescription medication and must be taken according to your doctor’s instructions.

Is Dulfre a stimulant?

Yes, Dulfre is a stimulant laxative, meaning it causes the muscles in your intestines to contract more often, allowing bowel movements to occur more quickly.

Is Dulfre safe for people with kidney or liver problems?

Yes, Dulfre is safe for people with kidney or liver problems. However, it is important to talk to your doctor about your specific condition before taking the medication.

Can I take Dulfre with other laxative medications?

No, Dulfre should not be taken with other laxatives or stool softeners. Talk to your doctor before taking any other medications while taking Dulfre.

Can Dulfre be used to treat diarrhea?

No, Dulfre is not used to treat diarrhea. It is a stimulant laxative specifically used to treat constipation.

Are there any known drug interactions with Dulfre?

Yes, Dulfre can interact with several drugs such as lithium, methotrexate, amiodarone, and some antibiotics. It’s important to tell your doctor about all medications you’re taking before starting to take Dulfre.

Does Dulfre have any side effects?

Common side effects can include stomach pain, cramps, bloating, gas, and diarrhea. If you experience any severe or persistent side effects, contact your doctor.

Can Dulfre be used for weight loss?

No, Dulfre is not meant for weight loss and should not be used as such. Talk to your doctor if you have any questions about weight loss.

Can Dulfre be taken on an empty stomach?

Yes, Dulfre can be taken with food or on an empty stomach.

Are there any foods or drinks I need to avoid while taking Dulfre?

It is best to avoid alcohol while taking Dulfre, as it can interact with the medication and cause adverse effects. Carefully follow your doctor’s instructions and warnings.

Can Dulfre be used in the treatment of irritable bowel syndrome?

No, Dulfre is not typically used in the treatment of irritable bowel syndrome. Talk to your doctor if you have any questions about the treatment of irritable bowel syndrome.

Is Dulfre safe for people with diabetes?

Yes, Dulfre is safe for people with diabetes. However, it is important to talk to your doctor about any special instructions or precautions to take while taking Dulfre.