Droperidolum
Droperidolum Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Droperidolum is a brand name. Its generic name is Droperidol.
Droperidolum Introduction
Droperidolum is an intravenous (IV) medication used to treat nausea, vomiting, and other symptoms of certain medical conditions such as schizophrenia, bipolar disorder, anxiety, and agitation. It is also used to treat headaches and vomiting associated with migraine headaches. It was first approved for in the United States in 1965.Uses for Droperidolum
Droperidolum is used to prevent and treat postoperative nausea and vomiting and used for treating schizophrenia, bipolar disorder, anxiety, and agitation. It has also been used to treat headaches and vomiting associated with migraine headaches.Mechanism of Action
Droperidolum works by blocking dopamine receptors in the brain, leading to reduced symptoms of agitation, anxiety, and nausea. It also works to reduce vomiting, migraine headaches, and excessive movement.How Long Does It Take to Work?
Droperidolum typically takes between 10 and 15 minutes to take effect after it is administered.Absorption
Droperidolum is rapidly and completely absorbed when administered intravenously.Route of Elimination
Droperidolum is rapidly metabolized in the liver and is primarily eliminated through urine.Dosage
The recommended dosage of Droperidolum is 0.125mg-2.5 mg given intravenously every 2-4 hours as needed.Administration
Droperidolum should be administered intravenously over 2 to 10 minutes.Side Effect
Common side effects of Droperidolum include drowsiness, dizziness, dry mouth, headache, confusion, blurred vision, and constipation. It may also cause restlessness, agitation, confusion, anxiety, tremor, and an irregular or fast heart rate.Toxicity
Prolonged use of Droperidolum can lead to a toxic reaction and severe cardiac and other side effects, including seizures, hallucinations, arrhythmias and torsade de pointes.Precaution
Patients should be monitored for signs of toxicity when taking Droperidolum. This medication should not be used in patients with a known history of QT prolongation, heart failure, or arrhythmias. It should be avoided in patients under 18 years of age and should not be used during pregnancy or while breastfeeding.Interaction
Droperidolum may interact with other medications such as narcotics, sedatives, MAO inhibitors, and other medications used to treat psychiatric disorders. It can also interact with alcohol, herbal supplements, and certain foods.Disease Interaction
Droperidolum may exacerbate certain underlying medical conditions such as cardiovascular disease, liver or kidney disease, Parkinson's disease, and schizophrenia.Drug Interaction
Droperidolum may interact with other drugs such as narcotic analgesics, sedatives, MAO inhibitors, and other medications used to treat psychiatric disorders.Food Interactions
Droperidolum may interact with certain foods such as alcohol, herbal supplements, and certain spices.Pregnancy Use
Droperidolum should not be used during pregnancy as it has been associated with congenital abnormalities.Lactation Use
Droperidolum should not be used while breastfeeding.Acute Overdose
An acute overdose of Droperidolum can lead to severe cardiac and other toxic reactions such as seizures, hallucinations, tachycardia, and arrhythmias. Treatments for an acute overdose include supportive measures such as cardiac monitoring and airway maintenance.Contraindication
Droperidolum should not be used in patients under 18 years of age and should not be used in those with a known history of QT prolongation, heart failure, or arrhythmias.Use Direction
Droperidolum should be used as directed by your physician. It should be administered intravenously over 2 to 10 minutes.Storage Condition
Droperidolum should be stored at room temperature in a tightly sealed container and away from heat and light.Volume of Distribution
The volume of distribution for Droperidolum is approximately 4.5 L/kg.Half Life
The half life of Droperidolum ranges from 3 to 5 hours.Clearance
The clearance of Droperidolum is approximately 16 ml/min per kg.Here you find in details version of Droperidolum
Some Frequently Asked Questions About Droperidolum
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