Doxobron

Doxobron Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Doxobron is a brand name. Its generic name is Doxofylline.

Introduction

Doxobron is an oral synthetic xanthine derivative used to treat and prevent wheezing or long-term breathing difficulty in people with asthma or other chronic pulmonary diseases such as COPD or emphysema. It is classified as a bronchodilator.

Uses for

Doxobron’s primary use is to help to open the airways in the lungs as it works as a bronchodilator. It is used in conditions such as asthma, chronic obstructive pulmonary disease (COPD), bronchitis, emphysema, and chronic bronchitis. In addition, Doxobron can also be used to treat nasal congestion, recurrent respiratory infections and difficulty in breathing during exercise.

Mechanism of Action

Doxobron works mainly by opening up the airways in the lungs. It achieves this by inhibiting the chemicals that cause the airways to become constricted or narrow. This relaxes the muscles in the airways allowing them to open wider, which makes it easier for the air to flow in and out of the lungs. This helps to reduce symptoms of asthma and other breathing difficulties as well as reducing the frequency of asthma attacks.

How Long Does it Take to Work?

Doxobron usually takes around 30 minutes to begin to take effect. The maximum effect is usually reached within one to four hours and the effects can last for up to six hours.

Absorption

Doxobron is rapidly and completely absorbed from the gastrointestinal tract. Peak plasma concentrations are reached within 1-2 hours of administration.

Route of Elimination

Doxobron is metabolised in the liver and is eliminated mainly by the kidneys. About 10-20% of the administered dose is excreted unchanged in the urine.

Dosage

The dosage of Doxobron will depend on the individual. It is available as 50, 100 and 400 mg tablets and can be taken once or twice a day. It is recommended to take the lowest dose that is effective in controlling the condition. For adults, the usual starting dose is 100 mg twice a day and the maximum dose is 400 mg twice a day.Children aged 6 years and above should take 6-12 mg/kg/day in two to three divided doses.

Administration

Doxobron should be taken exactly as your doctor has prescribed. It should be swallowed as a whole tablet with a glass of water and should not be crushed or chewed. The tablet should be taken before a meal or at bedtime.

Side Effect

The most common side effects of Doxobron are headache, nausea, vomiting, abdominal pain, diarrhoea, and loss of appetite. Other side effects include dizziness, insomnia, dry mouth, and rash.

Toxicity

Doxobron is not usually toxic in therapeutic doses, although an overdose of the drug may lead to serious side effects such as confusion, hallucinations, seizures, tachycardia, and respiratory depression. An overdose can be fatal if not treated immediately.

Precaution

Doxobron should be taken with caution in patients with kidney or liver impairment. It should be used with caution in patients with diabetes, as it may cause a decrease in blood sugar levels. Patients should be advised to monitor blood sugar levels. Patients with a history of seizures should also use caution when taking this drug.

Interaction

Doxobron can interact with certain medications, such as anticoagulants, oral contraceptives, and certain antibiotics. Alcohol can also interact with this drug and should be avoided. Patients should inform their doctor or pharmacist of all medications they are taking.

Disease Interaction

Doxobron should be used with caution in patients with certain diseases as it may worsen symptoms or cause side effects. These include diabetes, kidney or liver impairment, heart failure, an overactive thyroid, and certain eye diseases.

Drug Interactions

Doxobron can interact with certain drugs, including anticoagulants, diuretics, oral contraceptives, certain antibiotics, and other xanthine derivatives. Patients should inform their doctor or pharmacist of all medications they are taking.

Food Interactions

Food should be taken at least 2 hours (1 hour before or 1 hour after) after taking Doxobron to decrease its effects. Patients should avoid caffeine-containing foods and drinks such as coffee, tea, and chocolate during the course of treatment.

Pregnancy Use

Doxobron should be used with caution during pregnancy as it can cross the placenta and potentially cause harm to the fetus. It is not recommended for use during the first trimester of pregnancy.

Lactation Use

It is unknown whether Doxobron is excreted in human breast milk. Therefore, caution should be exercised when administering this drug to nursing mothers.

Acute Overdose

An acute overdose of Doxobron can lead to serious side effects such as confusion, hallucinations, seizures, tachycardia, and respiratory depression. Treatment of an overdose usually includes supportive care and symptomatic treatment.

Contraindication

Doxobron is contraindicated in patients with known hypersensitivity to xanthine derivatives, as well as in patients with severe liver or kidney impairment.

Use Direction

Doxobron should be taken as directed by the doctor or pharmacist. The tablets should be swallowed whole with a glass of water and should not be crushed or chewed. Take the drug at the same time every day and make sure to take the lowest dose that is effective in controlling the condition.

Storage Condition

Doxobron should be stored at a controlled room temperature of 15 to 30°C and must be kept away from light, moisture and heat. The tablets must be stored in a locked container and should be out of reach of children.

Volume of Distribution

The volume of distribution of Doxobron is approximately 0.6 L/kg. It is widely distributed into body tissues.

Half Life

The elimination half life of Doxobron is approximately 3.3 hours although it may vary in different individuals.

Clearance

The total clearance of Doxobron is approximately 17 mL/min/kg. The renal clearance is approximately 15 mL/min/kg.

Here you find in details version of Doxobron

Some Frequently Asked Questions About Doxobron

What is Doxobron?

Doxobron is a medicine used to treat breathing difficulties associated with asthma and chronic obstructive pulmonary disease (COPD). It works by relaxing the air passages and reducing the swelling of the lining of the airways.

Is Doxobron safe to take?

Yes, Doxobron is generally considered safe to take and is used to treat breathing difficulties associated with asthma and COPD. However, it is important to discuss any potential risks or side effects with your doctor before taking this medicine.

How do I take Doxobron?

Your doctor will provide you with instructions on how to take Doxobron correctly. It is important to follow these instructions and take the medicine as directed. In general, Doxobron is usually taken twice daily and should be taken with food.

What are the side effects of Doxobron?

Common side effects of Doxobron can include headache, nausea, stomach pain, and diarrhea. If you experience any severe or persistent side effects or if you have any questions regarding the medicine, contact your doctor as soon as possible.

Can I take Doxobron if I'm pregnant?

It is not recommended to take Doxobron if you are pregnant. If you become pregnant while taking this medicine, you should stop taking it and speak to your doctor right away.

What is the difference between Doxobron and Theophylline?

Both Doxobron and Theophylline are medicines used to treat breathing difficulties associated with asthma and COPD. Theophylline is a shorter-acting medicine than Doxobron and is usually taken four times a day. Doxobron is a longer-acting medicine and is typically taken twice a day.

Can I take other medications while taking Doxobron?

It is important to tell your doctor about all other medications you are taking before starting on Doxobron. Certain medications can interact with this medicine and may lead to unwanted side effects. Be sure to tell your doctor about all of the medications you are taking, including over-the-counter medicines, vitamins, and supplements.

Can I drink alcohol while taking Doxobron?

It is generally not recommended to drink alcohol while taking Doxobron. Alcohol can increase the risk of side effects and may also decrease the effectiveness of the medicine. If you have any questions or concerns, speak to your doctor.

How long does it take for Doxobron to work?

It usually takes about 48 to 72 hours for Doxobron to reach its full effect. If you have not noticed any improvement in your symptoms after this time, contact your doctor.

Is Doxobron habit-forming?

No, Doxobron is not considered to be habit-forming. However, it is important to take the medicine exactly as prescribed and not to take more than the recommended dosage.

What if I miss a dose of Doxobron?

If you forget to take a dose of Doxobron, take it as soon as you remember. If it is close to the time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.

Does Doxobron have any long-term side effects?

The long-term side effects of Doxobron vary depending on the person and the length of time they have been taking it. It is important to speak to your doctor about any potential risks or side effects before taking this medicine.

Can Doxobron cause headaches?

Yes, headaches are a common side effect of taking Doxobron. If you experience any severe or persistent headaches, speak to your doctor.

Can Doxobron make my breathing difficulties worse?

It is important to speak to your doctor if you experience any worsening of your breathing difficulties while taking Doxobron. Your doctor may need to adjust your dosage or recommend another medication.

Do I have to take Doxobron every day?

Yes, you should take Doxobron as directed by your doctor in order to maintain the best possible result. It is important to take this medicine every day as it takes some time for the drug to reach its full effect.

What should I do if I have an allergic reaction to Doxobron?

If you experience any allergic reactions to Doxobron such as difficulty breathing, swelling of the face, lips, or tongue, or hives, stop taking the medicine immediately and seek medical help. Be sure to let your doctor know if you have had any allergic reactions to this medicine in the past.

When can I expect to see results while taking Doxobron?

It typically takes about 48 to 72 hours for Doxobron to reach its full effect. If you have not noticed any improvements in your symptoms after this time, you should discuss this with your doctor.

Can I take Doxobron with other asthma medications?

It is generally safe to take Doxobron with other asthma medications. However, it is important to discuss this with your doctor before taking any other medicines, as they may interact with each other.

Can Doxobron help with difficulty breathing due to COPD?

Yes, Doxobron is used to treat breathing difficulties associated with chronic obstructive pulmonary disease (COPD). It works by relaxing the air passages and reducing the swelling of the lining of the airways.

What should I do if I experience an irregular heartbeat while taking Doxobron?

If you experience an irregular heartbeat or palpitations while taking Doxobron, stop taking the medicine and seek medical help right away. Be sure to let your doctor know if you have had any heart problems in the past.

Does Doxobron cause drowsiness?

Yes, drowsiness is a potential side effect of taking Doxobron. If you experience any drowsiness, you should not operate any heavy machinery or vehicles.

Can I take Doxobron while breastfeeding?

It is generally not recommended to take Doxobron while breastfeeding. If you are breastfeeding and need to take this medicine, you should discuss this with your doctor.

What if I forget to take Doxobron?

If you forget to take a dose of Doxobron, take it as soon as you remember. If it is close to the time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.

Can I take Doxobron while pregnant?

It is not recommended to take Doxobron if you are pregnant. If you become pregnant while taking this medicine, you should stop taking it and speak to your doctor right away.

Is it safe to take Doxobron with other medications?

It is important to tell your doctor about all other medications you are taking before starting on Doxobron. Certain medications can interact with this medicine and may lead to unwanted side effects. Be sure to tell your doctor about all of the medications you are taking, including over-the-counter medicines, vitamins, and supplements.

How much Doxobron should I take?

Your dose of Doxobron will depend on your medical condition and response to treatment. The dose may also be affected by other medications you are taking. You should always follow the instructions of your doctor and take the medicine exactly as directed.

What should I avoid while taking Doxobron?

It is important to avoid alcohol while taking Doxobron, as it may increase the risk of side effects and decrease the effectiveness of the medicine. Additionally, you should not operate any heavy machinery or vehicles, as the medicine may cause drowsiness.

Can I take Doxobron without food?

It is generally recommended to take Doxobron with food. Taking the medicine with food can help to reduce stomach upset and improve absorption of the drug. If you have any questions or concerns, speak to your doctor.

Does Doxobron have any serious side effects?

Yes, there are potential serious side effects associated with the use of Doxobron. These side effects can include shortness of breath, chest pain, irregular heartbeat, seizure, and rash. If you experience any of these symptoms, stop taking the medicine and seek medical help right away.

Can I take other asthma medications while on Doxobron?

It is generally safe to take other asthma medications while taking Doxobron. However, it is important to discuss this with your doctor before taking any other medicines, as they may interact with each other.

How long can I take Doxobron for?

The length of time you can take Doxobron for depends on your condition and response to treatment. It is important to follow your doctor’s instructions and not to stop taking the medication without their advice.

Can I take Doxobron while taking other medications?

It is important to tell your doctor about all other medications you are taking before starting on Doxobron. Certain medications can interact with this medicine and may lead to unwanted side effects. Be sure to tell your doctor about all of the medications you are taking, including over-the-counter medicines, vitamins, and supplements.

Can Doxobron cause nausea?

Yes, nausea is a potential side effect of taking Doxobron. If you experience any nausea, you should consult with your doctor. Your doctor may advise you to take the medicine with food or with an antacid.

What if I overdose on Doxobron?

If you overdose on Doxobron, seek medical help right away. Overdosing on this medicine may lead to serious side effects, such as difficulty breathing, chest pain, and irregular heartbeat.

Can Doxobron make my asthma symptoms worse?

It is important to speak to your doctor if you experience any worsening of your asthma symptoms while taking Doxobron. Your doctor may need to adjust your dosage or recommend a different medication.

Does Doxobron help with shortness of breath?

Yes, Doxobron is used to treat breathing difficulties associated with asthma and COPD, including shortness of breath. It works by relaxing the air passages and reducing the swelling of the lining of the airways.

Is Doxobron available over the counter?

No, Doxobron is not available over-the-counter. You must obtain this medicine through prescription from your doctor.

Should I take Doxobron in the morning or at night?

The timing of your dose of Doxobron is important and you should follow your doctor’s instructions regarding when to take the medicine. Generally, Doxobron is usually taken twice daily and should be taken with food.

Are there any safety precautions I should be aware of while taking Doxobron?

Yes, there are some safety precautions you should be aware of while taking Doxobron. These include avoiding alcohol, operating any heavy machinery or vehicles, and letting your doctor know if you have heart or kidney problems. Additionally, it is important to not take more than the recommended dosage of the medicine.