Dogmatil
Dogmatil Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Dogmatil is a brand name. Its generic name is Sulpiride.
Dogmatil Introduction
Dogmatil is an antipsychotic medicine and antidepressant that is mainly used to treat major depressive episodes and schizophrenia. It works by blocking certain receptors in the brain which makes less dopamine available and to reduce the effects of dopamine.
Uses for Dogmatil
Dogmatil is used for the treatment and prevention of manic episodes, schizophrenia, major depressive disorder, psychomotor agitation, dyskinesia, hallucinations, and Tourette’s syndrome.
Mechanism of Action
Dogmatil functions as an antagonist to dopamine receptors. It is believed to act as an antagonist to D2 receptors, blocking their action and thereby reducing the levels of dopamine in the brain. This is thought to reduce symptoms of mania, schizophrenia, depression, and psychomotor agitation.
How Long Does It Take to Work?
The effects of sulpiride can be felt within a few days. However, it may take up to six weeks for sulpiride to reach its full effect.
Absorption
Dogmatil is rapidly and almost completely absorbed from the gastrointestinal tract. Peak plasma concentrations occur 1-3 hours after oral administration.
Route of Elimination
Dogmatil is metabolized in the liver and eliminated mainly by the kidneys. Approximately 60% of an oral dose is recovered in the urine and 40% in the feces.
Dosage
The recommended dose of Dogmatil for adults is 200-1200 mg/day taken in two or three divided doses, depending on the individual response. For adolescents, the recommended dose is 50-300 mg/day. For children, the recommended dose is 25-150 mg/day. The dose should be adjusted according to the patient’s response and symptom relief.
Administration
Dogmatil should be taken orally with or without food. It is important to take it regularly in order to get the maximum benefit.
Side Effect
Common side effects of sulpiride include drowsiness, dry mouth, dizziness, constipation, vomiting, blurred vision, nausea, and restlessness. Other serious side effects may include allergic reactions, increased suicidal thoughts, low blood pressure, difficulty breathing, and sudden vision changes.
Toxicity
Dogmatil is generally safe and well-tolerated. It has a low potential for toxicity, even at supratherapeutic doses. In rare cases, overdose may cause nerve damage and other serious health complications.
Precaution
Before taking sulpiride, patients should inform their doctor of any pre-existing health conditions or allergies. Patients should also be aware of any potential drug interactions and be monitored regularly for changes in symptoms or side effects.
Interaction
Dogmatil may interact with other medicines and dietary supplements. Taking certain combinations of drugs can increase the risk of side effects or reduce efficacy. Patients should consult with their healthcare provider before taking any medications or dietary supplements.
Disease Interaction
Dogmatil may interact with certain diseases and medical conditions. Patients should discuss any pre-existing illnesses or medical conditions with their healthcare provider before taking sulpiride. In particular, patients should mention any history of liver or kidney disease, heart problems, diabetes, thyroid disease, or glaucoma.
Drug Interaction
Dogmatil may interact with certain medications and affect their efficacy. Patients should discuss any medications they are taking with their healthcare provider before taking sulpiride. Some of the drugs that may interact with sulpiride include Heamaglutinin Inhibitors, Antipsychotics, Mood Stabilizers, Selective Serotonin Reuptake Inhibitors (SSRIs), and Serotonin Norepinephrine Reuptake Inhibitors (SNRIs).
Food Interactions
Some foods may interact with sulpiride and alter its efficacy or increase the risk of side effects. Patients should avoid alcohol and grapefruit juice while taking sulpiride. Patients should also limit the consumption of caffeine and other stimulants, as these can increase the risk of side effects.
Pregnancy Use
Dogmatil is classified as a pregnancy Category C drug, meaning it may be unsafe during pregnancy. Patients should inform their healthcare provider if they become pregnant while taking sulpiride.
Lactation Use
Dogmatil is classified as a pregnancy Category D drug, meaning it is not recommended to be taken while breastfeeding. Patients should discuss with their healthcare provider whether breast-feeding is safe while taking sulpiride.
Acute Overdose
Immediate medical attention should be sought if an overdose is suspected. Common symptoms of an overdose include restlessness, confusion, tremors, speech problems, nausea, vomiting, and drowsiness.
Contraindication
Dogmatil should not be taken by patients with a known hypersensitivity or allergy to the drug. It should also not be taken by patients with liver or kidney impairment, heart disease, glaucoma or a personal or family history of Long QT Syndrome.
Use Direction
Dogmatil should be taken exactly as prescribed by a healthcare provider. Patients should take it twice or three times daily with or without food. Patients should not take more than the recommended dose and should never share their dose with others.
Storage Condition
Dogmatil tablets should be stored at room temperature, away from moisture and heat. Patients should keep the tablets in their original container and should not allow them to become outdated or expired.
Volume of Distribution
The volume of distribution of Dogmatil is 2-3 L/kg.
Half Life
The elimination half-life of Dogmatil is 8-15 hours in adults and 4-9 hours in elderly patients.
Clearance
The clearance of Dogmatil is 6-9 L/hr/kg in adults and 3.3-4.3 L/hr/kg in elderly patients.
Here you find in details version of Dogmatil
Some Frequently Asked Questions About Dogmatil
What is Dogmatil?
Dogmatil is an antipsychotic medicine used to treat mental and emotional disorders, including schizophrenia. It works by changing the activity of certain natural substances in the brain.
How does Dogmatil work?
Dogmatil works by changing the activity of certain natural substances in the brain. It blocks the action of dopamine, a neurotransmitter chemical that can cause psychotic symptoms such as hallucinations, delusions, and disorganized thinking.
What is Dogmatil used to treat?
Dogmatil is used to treat schizophrenia and other mental and emotional disorders such as bipolar disorder and depression.
What are the side effects of Dogmatil?
Common side effects of Dogmatil include nausea, dry mouth, dizziness, headache, drowsiness, restlessness, anxiety, agitation, insomnia, and weight gain.
Is Dogmatil safe for long-term use?
Yes, Dogmatil is safe for long-term use, but it should be used with caution as it can cause side effects. It is important to talk to your doctor about the risks and benefits of using Dogmatil for long-term treatment.
How do I take Dogmatil?
Dogmatil should be taken as directed by your doctor. It is important to follow your doctor's instructions precisely. Do not take more or less than prescribed. Tell your doctor if you have any problems with taking Dogmatil or any other drugs.
What should I avoid while taking Dogmatil?
You should avoid drinking alcohol while taking Dogmatil, as it may increase the risk of side effects. You should also avoid driving or operating heavy machinery until you know how the medication affects you. Talk to your doctor or pharmacist about other substances to avoid while taking Dogmatil.
Is Dogmatil habit forming?
No, Dogmatil is not habit forming. However, you should take it as prescribed and not use it for longer than your doctor recommends.
Can I take Dogmatil while pregnant or breastfeeding?
No, Dogmatil should not be taken during pregnancy or whilst breastfeeding, as it may cause harm to the developing baby. Talk to your doctor if you are pregnant or breastfeeding before taking Dogmatil.
Does Dogmatil interact with other medications?
Yes, Dogmatil can interact with other medications. It is important to tell your doctor and pharmacist all the medications you are taking before starting Dogmatil to help minimize interactions. Additionally, you should also tell your doctor if you are taking any medications that can cause drowsiness, as Dogmatil can add to this effect.
What should I do if I miss a dose of Dogmatil?
If you miss a dose of Dogmatil, take it as soon as possible. If it is close to the time for your next dose, skip the missed dose and continue with your regular schedule. Do not take two doses at once.
What should I do if I overdose on Dogmatil?
If you think you have overdosed on Dogmatil, seek medical attention immediately. Symptoms of an overdose can include confusion, sweating, muscle stiffness, unusual movements, low blood pressure, seizures, and coma.
What are the storage conditions for Dogmatil?
Dogmatil should be stored at room temperature, away from light and moisture. Keep the medication in a secure place where it cannot be accessed by others. Do not keep it in the bathroom, near the kitchen sink, or in other damp places.
How long does it take for Dogmatil to work?
The effects of Dogmatil may vary from person to person. It usually takes several weeks to start feeling the full effects of the medication. It is important to keep taking the medication even if you feel like it is not working.
Are there any supplement or dietary restrictions when taking Dogmatil?
Yes, you should not take iron or multivitamin supplements while taking Dogmatil. You should also avoid drinking grapefruit juice and eating large amounts of grapefruit when taking this medication, as it can increase the risk of side effects.
Is there an alternative to Dogmatil?
Yes, other antipsychotic medications such as clozapine, risperidone, olanzapine, and quetiapine are also used to treat the same conditions. Talk to your doctor about the pros and cons of these medications and which one might be best for you.
What are the most common side effects of Dogmatil?
The most common side effects of Dogmatil include nausea, dry mouth, dizziness, headache, drowsiness, restlessness, anxiety, agitation, insomnia, and weight gain.
Can I take other medications with Dogmatil?
Yes, you can take other medications with Dogmatil, but you should always tell your doctor and pharmacist about all the medications you are taking before starting Dogmatil. Some medications can interact with Dogmatil and cause side effects. Talk to your doctor or pharmacist about other substances to avoid while taking Dogmatil.
Does Dogmatil have any withdrawal symptoms?
Yes, abruptly stopping Dogmatil can cause withdrawal symptoms such as confusion, anxiety, shakiness, tremors, increased heart rate, and insomnia. Talk to your doctor before stopping Dogmatil. Your doctor can help you stop it safely with a gradual decrease in dosage.
Does Dogmatil cause weight gain?
Yes, Dogmatil can cause weight gain in some people. Talk to your doctor about this and ways to manage it if it becomes a problem.
Does Dogmatil cause depression?
Dogmatil can cause depression in some people. Talk to your doctor if you experience any signs of depression such as feelings of sadness, hopelessness, or loss of interest in activities while taking Dogmatil.
Can Dogmatil be used for anxiety?
No, Dogmatil is not approved for the treatment of anxiety disorders. Talk to your doctor about other medications that may be more suitable for the treatment of anxiety.
Can I drink alcohol while taking Dogmatil?
No, it is not recommended to drink alcohol while taking Dogmatil as it can increase the risk of side effects. Talk to your doctor before drinking alcohol while taking Dogmatil.
What happens if I stop taking Dogmatil suddenly?
If you stop taking Dogmatil suddenly, you may experience withdrawal symptoms such as confusion, anxiety, shakiness, tremors, increased heart rate, and insomnia. Talk to your doctor before stopping Dogmatil. Your doctor can help you stop it safely with a gradual decrease in dosage.
Is Dogmatil addictive?
No, Dogmatil is not considered to be addictive. However, you should use caution and take it as prescribed by your doctor, not more or less.
Can children take Dogmatil?
No, Dogmatil is not approved for use in children. Talk to your doctor about other medications that may be more suitable for children.
What is the recommended dosage for Dogmatil?
The recommended dosage of Dogmatil can vary from person to person. Your doctor will prescribe a dosage that is best for you. Do not take more or less than prescribed by your doctor.
Is there an injectable form of Dogmatil?
Yes, there is an injectable form of Dogmatil, known as Dogmatil LA. It is only available with a prescription from your doctor.
Is there a generic version of Dogmatil available?
Yes, there is a generic version of Dogmatil available in the US. Talk to your doctor or pharmacist about generic alternatives to Dogmatil.
How long does it take for Dogmatil to leave the body?
Dogmatil has an elimination half-life of between 12 to 24 hours. This means that it takes about one day for the drug to be completely eliminated from the body.
Does Dogmatil have any interaction with other drugs?
Yes, Dogmatil can interact with other drugs. It is important to tell your doctor and pharmacist about all the medications you are taking before starting Dogmatil to help minimize interactions. Additionally, you should also tell your doctor if you are taking any medications that can cause drowsiness, as Dogmatil can add to this effect.
Does Dogmatil cause sleepiness?
Yes, Dogmatil can cause sleepiness. If you experience sleepiness or drowsiness while taking Dogmatil, you should avoid driving, operating machinery, or performing other activities that require alertness.
Can I take over-the-counter medications while taking Dogmatil?
Yes, you can take over-the-counter medications with Dogmatil, but you should always tell your doctor and pharmacist about all the medications you are taking before starting Dogmatil to help minimize interactions. Additionally, you should also tell your doctor if you are taking any medications that can cause drowsiness, as Dogmatil can add to this effect.
Can I take herbal supplements while taking Dogmatil?
No, you should not take herbal supplements while taking Dogmatil, as they can interact with the medication and increase the risk of side effects. Talk to your doctor before taking any herbal supplements.
Can I take vitamins while taking Dogmatil?
No, you should not take iron or multivitamin supplements while taking Dogmatil. You should also avoid drinking grapefruit juice and eating large amounts of grapefruit when taking this medication, as it can increase the risk of side effects.
Can I take Dogmatil with food?
Yes, Dogmatil can be taken with food. However, it is best to take it with a full glass of water or milk to reduce the risk of stomach upset.
What other substances should I avoid while taking Dogmatil?
You should avoid drinking alcohol while taking Dogmatil, as it may increase the risk of side effects. You should also avoid driving or operating heavy machinery until you know how the medication affects you. Talk to your doctor or pharmacist about other substances to avoid while taking Dogmatil.
Does Dogmatil cause hair loss?
Yes, Dogmatil can cause hair loss in some people. Talk to your doctor if you experience hair loss while taking Dogmatil.
Does Dogmatil cause constipation?
Yes, Dogmatil can cause constipation in some people. Talk to your doctor if you experience constipation while taking Dogmatil.
Does Dogmatil cause diarrhea?
Yes, Dogmatil can cause diarrhea in some people. Talk to your doctor if you experience diarrhea while taking Dogmatil.
Does Dogmatil cause dry mouth?
Yes, Dogmatil can cause dry mouth in some people. Talk to your doctor if you experience dry mouth while taking Dogmatil.
Does Dogmatil cause weight loss?
No, Dogmatil does not typically cause weight loss, but it can cause weight gain in some people. Talk to your doctor about any changes in your weight while taking Dogmatil.
Does Dogmatil cause joint pain?
Yes, Dogmatil can cause joint pain in some people. Talk to your doctor if you experience joint pain while taking Dogmatil.
Can I take aspirin while taking Dogmatil?
Yes, you can take aspirin while taking Dogmatil, but you should always tell your doctor and pharmacist about all the medications you are taking before starting Dogmatil to help minimize interactions.