Cyclogyl

Cyclogyl Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Cyclogyl is a brand name. Its generic name is Cyclopentolate.

Introduction

Cyclogyl is a synthetic anticholinergic drug. It is an acetylcholine receptor antagonist primarily used to decrease intraocular pressure in the diagnosis and treatment of certain kinds of plateau iris, pupillary dilation, anterior and posterior synechiae as well as treatment of esotropia. It is also prescribed for angle closure glaucoma.

Uses

Cyclogyl is used to treat a wide range of ophthalmologic conditions including, but not limited to, intraocular pressure, pupillary dilation, anterior and posterior synechiae, esotropia, and angle closure glaucoma.

Mechanism of Action

Cyclogyl works at acetylcholine receptors and acts as an antagonistic drug against acetylcholine. Its blocking action at cholinergic receptors prevents contraction of radial, circular, and longitudinal muscles, resulting in mydriasis (pupillary dilation), cycloplegia (paralysis of the muscles controlling accommodation for near vision), and decreased intraocular pressure. Cyclogyl is often combined with epinephrine to produce an even stronger mydriatic and cycloplegic effect.

How Long does it Take to Work?

Cyclogyl takes approximately 5-10 minutes to produce its maximal effects. However, its duration of action can last anywhere from days to weeks depending on the dosage and individual.

Absorption

Cyclogyl is rapidly and completely absorbed following topical application to the eyes and systemic absorption is minimal.

Route of Elimination

Cyclogyl is rapidly metabolized to inactive metabolites and is eliminated mainly through urine.

Dosage

The dosage of Cyclogyl depends upon the condition being treated and the particular patient’s response to treatment. The recommended dosage is 1 to 2 drops of she 0.5% ophthalmic solution in each affected eye, 1 to 3 times daily.

Administration

Cyclogyl must be administered accurately and carefully. Wash hands and apply a clean strip of gauze to the lower eyelid. Remain in a seated position and look up slightly. Squeeze two drops of the solution into the affected eye, being careful not to touch the eyelids with the dropper. Close the eyelid gently for 1 to 2 minutes and repeat in the other eye, if necessary.

Side Effects

Possible side effects from Cyclogyl include stinging, burning, itching, blurred vision, temporary increase in intraocular pressure, photophobia, discomfort, nausea, dry mouth, dizziness, confusion, agitation, irritability, and confusion.

Toxicity

Topical application of cyclopentolate may result in mild to moderate systemic toxicity, although serious toxicity from systemic absorption is considered rare. Symptoms of systemic toxicity include nausea, vomiting, rash, headache, delirium, hemolysis, amblyopia, tachycardia, and hypertension.

Precaution

Use caution when administering cyclopentolate to patients with high risk of angle closure glaucoma, patients with cardiovascular disease, or those with severe glaucoma. Patients should avoid driving, operating machinery, and other activities requiring clear vision during treatment with cyclopentolate. Use of contact lenses should be avoided during treatment. It is also important to inform the patient that the effects of cyclopentolate can take several days to wear off.

Interactions

Drug interactions have not been reported with Cyclogyl. However, other ophthalmic medications should not be used within five minutes of each other due to the possibility of interaction.

Disease Interaction

Cyclogyl should be used cautiously in patients with cardiovascular disease, as mydriasis and increased heart rate can worsen existing heart conditions.

Drug Interaction

Drug interactions have not been reported with Cyclogyl. However, other ophthalmic medications should not be used within five minutes of each other due to the possibility of interaction.

Food Interactions

Cyclogyl has no known food interactions.

Pregnancy Use

Cyclogyl should be used with caution in pregnant women. Clinical studies investigating the safety of Cyclogyl during pregnancy have not been performed.

Lactation Use

The safety of Cyclogyl during lactation has not been established. Patients should consult their health care provider before using Cyclogyl while nursing.

Acute Overdose

Overdose of cyclopentolate can lead to mydriasis, cycloplegia, increased intraocular pressure, confusion, delirium, agitation, and hypertension. Treatment of overdose includes symptomatic and supportive care.

Contraindication

Cyclogyl should not be used in patients who are hypersensitive to the medication.

Use Direction

Cyclogyl must be used as directed by the doctor or pharmacist. Read the patient information leaflet for complete directions on use.

Storage Condition

Cyclogyl should be stored at room temperature, away from heat and light. Keep out of the reach of children.

Volume of Distribution

The volume of distribution for Cyclogyl is not known.

Half Life

The half life of Cyclogyl is not known.

Clearance

The clearance for Cyclogyl is not known.

Here you find in details version of Cyclogyl

Some Frequently Asked Questions About Cyclogyl

Where does Cyclogyl come from?

Cyclogyl is a type of anticholinergic medication. It is derived from plants of the nightshade family such as belladonna and jimsonweed.

What is Cyclogyl used for?

Cyclogyl is a medication used to reduce intraocular pressure in the eyes to treat glaucoma and to treat adjective spasms or paralysis of the eye muscles.

Is Cyclogyl a steroid?

No, Cyclogyl is not a steroid. It is an anticholinergic medication.

How long does Cyclogyl take to work?

Cyclogyl typically begins to work within a few minutes to an hour after it has been administered.

What are the side effects of Cyclogyl?

The most common side effects of Cyclogyl include blurred vision, dilation of the pupils (mydriasis), sensitivity to light (photophobia), headache, and eye irritation.

How much Cyclogyl should I take?

The appropriate dose of Cyclogyl depends on a variety of factors such as the condition being treated, age, weight, and other medications being taken. It is important to follow the directions on the prescription label and only take the prescribed amount.

Is Cyclogyl safe for use during pregnancy?

Cyclogyl is classified as a pregnancy category C medication, which means that it may be harmful to an unborn baby. Women who are pregnant or planning to become pregnant should speak to a doctor prior to taking Cyclogyl.

Is it ok to drive after taking Cyclogyl?

It is not recommended to drive vehicles or operate machinery after taking Cyclogyl, as it can cause blurred vision and drowsiness.

Should I avoid alcohol while taking Cyclogyl?

Yes, it is recommended to avoid alcohol while taking Cyclogyl, as it may increase the risk of side effects such as drowsiness and dizziness.

Is there an alternative to Cyclogyl?

Yes, there are other medications that are used to treat the same conditions as Cyclogyl. Speak with your doctor to determine the best treatment option for you.

Is it safe to use Cyclogyl for long periods of time?

It is recommended to follow the instructions on the prescription label and only take Cyclogyl for the recommended amount of time. Long-term use of Cyclogyl may increase the risk of side effects.

What should I do if I miss a dose of Cyclogyl?

If you miss a dose of Cyclogyl, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the next dose when it is due.

Can Cyclogyl be taken with other medications?

It is important to inform your doctor about all medications being taken, including prescription, over-the-counter, herbal, and vitamin supplements. Certain medications can interact negatively with Cyclogyl, so it is important to follow the instructions on the prescription label.

Can Cyclogyl be used to treat allergies?

No, Cyclogyl is not used to treat allergies. It is used to reduce intraocular pressure in the eyes to treat glaucoma and to treat adjective spasms or paralysis of the eye muscles.

Does Cyclogyl cause drowsiness?

Yes, Cyclogyl can cause drowsiness. It is important to avoid operating vehicles or machinery while taking Cyclogyl.

Can Cyclogyl be used in children?

Cyclogyl can be used in children over the age of three years as long as it is prescribed by a doctor. It should not be used in infants and young children.

What are the precautions for taking Cyclogyl?

It is important to take Cyclogyl exactly as prescribed by a doctor. It should not be taken more often than prescribed, and the dose should not be increased without first consulting a doctor. It is also important to inform your doctor of any medications being taken, including prescription, over-the-counter, herbal, and vitamin supplements.

What should I do if I experience an allergic reaction to Cyclogyl?

If you experience an allergic reaction to Cyclogyl, such as hives, difficulty breathing, or swelling of the face, lips, tongue, or throat, seek medical attention immediately.

What if I experience an increase in intraocular pressure after taking Cyclogyl?

If you experience an increase in intraocular pressure after taking Cyclogyl, seek medical attention immediately.

Can I wear contact lenses while taking Cyclogyl?

No, it is not recommended to wear contact lenses while using Cyclogyl. Speak with your eye doctor prior to inserting contact lenses.

Is there a generic version of Cyclogyl?

Yes, Cyclogyl is available in generic form.

What should I do if Cyclogyl does not seem to be working?

If Cyclogyl does not seem to be working, it is important to speak to your doctor for further advice.

Can I take Cyclogyl with a decongestant?

Yes, you can take Cyclogyl with a decongestant. However, it is important to inform your doctor about all medications being taken, including prescription, over-the-counter, herbal, and vitamin supplements.

Can I use eye drops after taking Cyclogyl?

Yes, you can use eye drops after taking Cyclogyl. However, it is important to always follow the instructions of your doctor.

What should I do if my vision does not improve after taking Cyclogyl?

If your vision does not improve after taking Cyclogyl, it is important to seek medical attention as soon as possible.

When will I notice the effects of Cyclogyl?

The effects of Cyclogyl can usually be noticed within a few minutes to an hour after taking it.

What is the difference between Cyclogyl and Atropine?

Atropine is another type of anticholinergic medication. It is generally longer-acting than Cyclogyl and is used to dilate the pupil.

Does Cyclogyl have any interaction with alcohol?

Yes, Cyclogyl should not be taken with alcohol, as it may increase the risk of side effects such as drowsiness and dizziness.

What are the common side effects of Cyclogyl?

The most common side effects of Cyclogyl include blurred vision, dilation of the pupils (mydriasis), sensitivity to light (photophobia), headache, and eye irritation.

Does Cyclogyl cause dry eyes?

Yes, Cyclogyl can cause dry eyes. If dry eyes become bothersome, speak with your doctor.

Does Cyclogyl have any interactions with other medications?

Yes, Cyclogyl can interact with certain medications. It is important to inform your doctor of all medications being taken, including prescription, over-the-counter, herbal, and vitamin supplements.

How long do the effects of Cyclogyl usually last?

The effects of Cyclogyl typically last around 4 to 6 hours.

How should I store Cyclogyl?

Cyclogyl should be stored at room temperature away from light and moisture.

Can I take Cyclogyl if I have glaucoma?

Yes, Cyclogyl can be used to treat glaucoma. Speak with your doctor to determine if Cyclogyl is the right treatment option for your condition.

Are there any interactions between Cyclogyl and food?

No, there are no known interactions between Cyclogyl and food.

Can I wear sunglasses while taking Cyclogyl?

Yes, it is recommended to wear sunglasses while taking Cyclogyl to protect the eyes from strong sunlight.

Should I stop taking Cyclogyl if I experience side effects?

If you experience side effects such as blurred vision, dilation of the pupils, sensitivity to light, headache, or eye irritation, speak to your doctor for further advice.

What should I do if I accidentally take more than the recommended dose of Cyclogyl?

If you accidentally take more than the recommended amount of Cyclogyl, seek medical attention immediately.

Can Cyclogyl be taken with other eye medications?

Yes, Cyclogyl can be taken with other eye medications. However, it is important to inform your doctor of all medications being taken, including prescription, over-the-counter, herbal, and vitamin supplements.

Can I take Cyclogyl if I have asthma?

Yes, Cyclogyl can be taken if you have asthma. However, it is important to inform your doctor of any medications being taken, including prescription, over-the-counter, herbal, and vitamin supplements.

Can Cyclogyl cause blurred vision?

Yes, blurred vision is a common side effect of Cyclogyl.