Corvela

Corvela Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Corvela is a brand name. Its generic name is Ranolazine.

Introduction

Corvela is a medication used to treat chronic angina (chest pain). It works by increasing the amount of oxygen that is available to the heart muscle during periods of physical exertion and stress. It is usually given as an extended-release tablet that is taken twice a day.

Uses

Corvela is used to treat chronic angina (chest pain) in adults. It works by increasing the amount of oxygen that is available to the heart muscle during periods of physical exertion and stress.

Mechanism of Action

Corvela works by inhibiting the late sodium current. This reduces extrusion of calcium ions from cells within the heart muscle, which increases the amount of oxygen available to the heart muscle.

How Long Does It Take to Work?

The effects of Corvela may be seen within a few hours after a single dose, but it usually takes 3-4 weeks of regular twice daily dosing for the full effects of Corvela to appear.

Absorption

Corvela is rapidly absorbed after oral administration, with peak concentrations occurring in 1-2 hours.

Route of Elimination

Corvela is excreted primarily in the urine as unchanged drug and as its metabolites.

Dosage

The typical dose of Corvela is 500 mg taken twice daily. The dose may be adjusted by your doctor based on your response to the medication.

Administration

Corvela should be taken twice daily with or without food. It should be taken at the same time each day to maintain an even level of the drug in your blood.

Side Effects

Common side effects of Corvela may include nausea, dizziness, headache, fatigue, constipation, and diarrhea.

Toxicity

There is no known specific antidote for overdose with Corvela. Treatment should be supportive and symptomatic.

Precautions

Corvela should not be used in patients with moderate or severe hepatic impairment.

Interactions

Corvela should not be used in combination with other medications that reduce the oxygen levels in the heart such as ranolazine nitroglycerin and other nitrates.

Disease Interactions

Corvela should not be used in patients with advanced kidney dysfunction or coronary artery disease.

Drug Interactions

Corvela may interact with certain medications such as antifungals, antibiotics, HIV medications, cancer treatments, seizure medications, and heart rhythm medications.

Food Interactions

Corvela should not be taken with high fat or high protein foods as it can affect the absorption of the drug.

Pregnancy Use

Corvela should not be used in pregnant women unless the potential benefit outweighs the risks.

Lactation Use

Corvela should not be used while breastfeeding as it is not known if it is safe for the infant.

Acute Overdose

Overdose of ranolazine may cause nausea, vomiting, dizziness, seizures, and coma. Treatment should be supportive and symptomatic.

Contraindication

Corvela is contraindicated in patients with moderate to severe hepatic impairment or advanced kidney dysfunction.

Use Directions

Corvela should be taken as directed by your doctor. It is typically taken twice daily with or without food.

Storage Condition

Corvela should be stored at room temperature away from moisture and heat.

Volume of Distribution

The volume of distribution for Corvela is 12 L.

Half Life

The half-life of Corvela is 8.2 hours.

Clearance

Corvela has a clearance of 4.5 L/hr.

Here you find in details version of Corvela

Some Frequently Asked Questions About Corvela

What is Corvela?

Corvela is an oral anti-anginal drug used to treat chronic angina (chest pain). It is meant to be taken in combination with other anti-anginal medications when all other treatments have failed to provide adequate relief for chest pain.

Who should take Corvela?

Corvela is approved for use in adults with chronic angina who are taking other anti-anginal medications. Your doctor will assess your medical history and any other medications you are taking before prescribing Corvela.

How do I take Corvela?

Corvela is usually taken twice daily with or without food. Do not change your dose or stop taking Corvela without consulting your doctor. If you miss a dose, take it as soon as you remember. Do not double your dose.

What are the side effects of Corvela?

Common side effects of Corvela include nausea, dizziness, headache, constipation, diarrhea, and fatigue. More serious side effects may include an irregular heartbeat, low blood pressure, and allergic reactions. If you experience any side effects, contact your doctor immediately.

What should I avoid while taking Corvela?

You should avoid drinking alcohol while taking Corvela as it can increase the risk of side effects. You should also avoid driving or operating machinery until you know how Corvela affects you. Do not take any other anti-anginal medications while taking Corvela without consulting your doctor.

What should I tell my doctor before taking Corvela?

Tell your doctor about any other medications you are taking, including over-the-counter medications, supplements, and herbal remedies. Inform your doctor if you have any allergies, kidney or liver disease, or heart problems. Also, tell your doctor if you are pregnant, planning to become pregnant, or breastfeeding before taking Corvela.

Is Corvela a controlled substance?

No, Corvela is not a controlled substance.

How does Corvela work?

Corvela works by improving the flow of oxygen-rich blood to the heart. It interferes with the normal cycle of fat metabolism in cells, which allows more energy to reach the heart muscles during strenuous activity. This increased energy helps reduce chest pains.

What should I do if I overdose on Corvela?

If you think you have overdosed on Corvela, contact your local poison control center or emergency room immediately. Symptoms of an overdose include confusion, dizziness, fainting, and an irregular heartbeat.

How long does it take for Corvela to work?

The effects of Corvela may be felt relatively quickly but it may take up to 8 weeks before the full effects can be experienced. It's important to take Corvela as prescribed and to continue taking it to get the most benefit.

What other medications may interact with Corvela?

Certain medications may interact with Corvela, including certain antibiotics, HIV medications, cholesterol-lowering medications, seizure medications, and medications for heart arrhythmia. Before taking Corvela, make sure to inform your doctor of any other medications you are taking.

Is Corvela available in generic form?

No, Corvela is not available in generic form.

Can I take Corvela while pregnant or breastfeeding?

No, Corvela is not recommended for use in pregnant or breastfeeding women as it may cause harm to the developing baby. Consult your doctor before taking Corvela if you are pregnant or breastfeeding.

Can I take Corvela with other medications for angina?

Corvela is meant to be taken in combination with other anti-anginal medications, so it is safe to take with other medications for angina. Be sure to inform your doctor of all medications you are taking to ensure there are no possible interactions.

Can Corvela be used to treat other conditions?

No, Corvela is specifically approved to treat chronic angina and should not be used to treat any other condition. If you are experiencing symptoms of other conditions, consult your doctor to discuss other treatment options.

Does Corvela have any long-term effects?

Currently there is not enough data to determine whether there are any long-term effects of taking Corvela. It is important to take Corvela exactly as prescribed by your doctor and to contact your doctor if you experience any persistent side effects.

Is there a generic form of Corvela available?

No, Corvela is not available in generic form.

Can Corvela be taken with other medications?

Corvela can be taken with other medications, but you should always inform your doctor of any other medications you are taking to ensure there are no potential interactions. Corvela should not be taken with any other anti-anginal medications.

Is Corvela safe to take long-term?

Corvela is generally safe to take long-term, but you should inform your doctor of any side effects you experience. It is important to take Corvela exactly as prescribed to get the maximum benefit.

What should I do if I miss a dose of Corvela?

If you miss a dose, take it as soon as you remember. Do not double your dose. If you have taken an extra dose, contact your doctor right away.

What are the symptoms of angina?

Symptoms of angina include chest pain or discomfort, feeling tired or weak, shortness of breath, anxiety, or pain in the jaw, neck, back, or arms. If you are experiencing these symptoms, contact your doctor to discuss treatment options.

How long does it take to see the effects of Corvela?

The effects of Corvela may be felt relatively quickly but it may take up to 8 weeks before the full effects can be experienced. It's important to take Corvela as prescribed and to continue taking it to get the most benefit.

What are the possible side effects of Corvela?

Common side effects of Corvela include nausea, dizziness, headache, constipation, diarrhea, and fatigue. More serious side effects may include an irregular heartbeat, low blood pressure, and allergic reactions. If you experience any side effects, contact your doctor immediately.

Is Corvela habit-forming?

No, Corvela is not habit-forming.

Can children take Corvela?

No, Corvela is not approved for use in children.

Can I drink alcohol while taking Corvela?

No, you should not drink alcohol while taking Corvela as it can increase the risk of side effects.

Is Corvela safe for people with kidney or liver conditions?

Corvela should be used with caution in people with kidney or liver conditions as they may be more likely to experience side effects. Consult your doctor to discuss the risks and benefits of taking Corvela if you have any kidney or liver conditions.

Can people with heart conditions take Corvela?

Corvela should be used with caution in people with heart conditions. Consult your doctor to discuss the risks and benefits of taking Corvela if you have any heart conditions.

Does Corvela cause weight gain?

No, Corvela does not typically cause weight gain.

Can Corvela be split or crushed?

No, Corvela should not be split or crushed. It should be taken as whole tablet. If you have difficulty swallowing a tablet, contact your doctor to discuss other options.

Is Corvela covered by insurance?

It depends on your insurance plan. Contact your insurance provider to find out if Corvela is covered by your plan.

What is the cost of Corvela?

The cost of Corvela will depend on your insurance coverage and pharmacy. Contact your insurance provider and pharmacy to find out the cost of Corvela.

Can Corvela be taken on an empty stomach?

Yes, Corvela can be taken with or without food.

Can Corvela be taken with food?

Yes, Corvela can be taken with or without food.

Can Corvela be used to prevent chest pain?

Yes, Corvela can be used to reduce chest pain caused by chronic angina.

Does Corvela interact with any herbs or supplements?

Yes, certain herbs and supplements may interact with Corvela. Be sure to inform your doctor of any herbs or supplements you are taking before taking Corvela.

Is Corvela effective at reducing chest pain?

Yes, Corvela is effective at reducing chest pain caused by chronic angina.

Does Corvela cause any withdrawal symptoms?

No, Corvela does not cause any withdrawal symptoms.

Can I breastfeed while taking Corvela?

No, Corvela is not recommended for use in breastfeeding women as it may cause harm to the developing baby. Consult your doctor before taking Corvela if you are breastfeeding.