Cloxafu

Cloxafu Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Cloxafu is a brand name. Its generic name is Flucloxacillin.

Introduction

Cloxafu is an antibiotic belonging to the penicillin family. It is used to treat infections caused by both Gram positive and Gram negative bacteria. It is available in most countries either as a generic drug or as branded versions.

Uses

Cloxafu is primarily used to treat a wide range of bacterial infections including infections of the respiratory tract, skin, and urinary tract. It is also used to treat some sexually transmitted diseases such as gonorrhea.

Mechanism of Action

Cloxafu works by inhibiting synthesis of bacterial cell wall. It attaches itself to enzymes responsible for cross-linking peptidoglycans molecules. This prevents these enzymes from functioning, effectively killing the bacterial cell.

How Long Does it Take to Work

Cloxafu should start working within 12 to 24 hours of taking the medicine. However, it is important to take the medication as prescribed, and for the entire course of treatment, in order to get the full benefit.

Absorption

Cloxafu is absorbed through the walls of the upper gastrointestinal tract. It is rapidly absorbed, reaching a peak concentration in one hour.

Route of Elimination

Cloxafu is eliminated mainly through the urine. It is also excreted in bile.

Dosage

Cloxafu is available in various dosage forms and strengths. The dosage usually depends on the type and severity of the infection being treated, as well as the patient’s age, weight, and kidney function. Common oral dosage forms and strengths include 250 mg, 500 mg, and 750 mg capsules. Common IV dosage forms and strengths include 500 mg, 1 g, and 2 g vials. Dosage should be determined by a doctor or pharmacist.

Administration

The medication can be taken orally with or without food, or it can be administered intravenously. If administered IV, it should be diluted with a compatible IV solution, such as normal saline, and administered slowly.

Side Effect

Common side effects of Cloxafu may include nausea, diarrhea, vomiting, headache, and skin rash or itching. In rare cases it can cause severe allergic reactions or anaphylaxis. Serious side effects, such as watery or bloody diarrhea and flu-like symptoms, may require immediate medical attention.

Toxicity

Cloxafu is considered to have relatively low toxicity when taken at the recommended dose. Overdose may lead to nausea, vomiting, abdominal pain, and other symptoms.

Precaution

Cloxafu should be taken with caution if you are allergic to other medicines in the penicillin family, or if you have any other allergies. It should also be used with caution if you have preexisting kidney or liver problems.

Interaction

Cloxafu can interact with some other medications. It is important to tell your doctor or pharmacist about all medications, vitamins, and supplements you are taking before starting to take this medication.

Disease Interaction

Cloxafu should be used with caution if you have certain diseases such as diabetes, kidney disease, blood diseases, or liver disease.

Drug Interaction

Cloxafu may interact with other medications such as antacids, birth control pills, and some blood pressure medications.

Food Interactions

Cloxafu should be taken with food to minimize gastric irritation.

Pregnancy Use

Cloxafu is not recommended for pregnant women due to the potential risk of harm to the fetus.

Lactation Use

Cloxafu should not be used during lactation due to the potential risk of compromising the quality of breast milk.

Acute Overdose

In the case of an acute overdose, it is important to seek medical attention immediately. Symptoms may include nausea, vomiting, abdominal pain, and other symptoms.

Contraindication

Cloxafu is contraindicated in patients who are allergic to penicillins, cephalosporins, or any other antibiotic.

Use Direction

Cloxafu should be taken exactly as prescribed by your doctor or pharmacist. It should not be taken longer than the prescribed course of treatment as this increases the risk of developing bacterial resistance.

Storage Condition

Cloxafu should be stored at room temperature and away from direct sunlight.

Volume of Distribution

Cloxafu has a large volume of distribution. It is distributed into most body tissues and fluids, including saliva, semen, and cerebrospinal fluid.

Half Life

The half-life of flucloxacillin is 1.5 - 2 hours.

Clearance

Cloxafu is cleared by both renal and non-renal mechanisms. It is primarily cleared by the kidneys, but it is also cleared by metabolism and excretion into bile.

Here you find in details version of Cloxafu

Some Frequently Asked Questions About Cloxafu

What is Cloxafu?

Cloxafu is a type of antibiotic, and it belongs to a group of medicines called 'penicillins'. It is used to treat bacterial infections, such as skin, chest, urine, and ear infections caused by susceptible organisms.

What is it used to treat?

Cloxafu is used to treat bacterial infections, such as skin, chest, urinary, and ear infections, caused by susceptible organisms.

How does Cloxafu work?

Cloxafu works by stopping the bacteria from multiplying and killing them. It also helps the body's own natural defenses to fight the infection.

How quickly does Cloxafu work?

Cloxafu usually starts working within a few days and will often work within 24 hours, but it might take slightly longer to get rid of all the bacteria causing the infection.

How long should I take Cloxafu?

It is important to take Cloxafu for as long as your doctor has prescribed it for you. This is usually 5 to 10 days after your symptoms have gone. Stopping the medicine too soon could make the infection come back.

Is Cloxafu the same as Penicillin?

No, Cloxafu is a type of penicillin, but it is a more powerful form of penicillin that is used to treat more serious bacterial infections.

Can I drink alcohol while taking Cloxafu?

It is not advisable to drink alcohol while taking any type of antibiotic. Alcohol can reduce the effectiveness of the antibiotic, and can also increase the risk of side effects such as nausea and vomiting.

Do I need to take Cloxafu with food?

Cloxafu does not need to be taken with food. However, if you experience any stomach discomfort or an upset stomach while taking the medicine, then taking it with food may help.

Can I take Cloxafu while pregnant?

Generally, Cloxafu is safe to take while pregnant, but it is important to speak to your doctor before taking any medication while pregnant.

Does Cloxafu have any side effects?

Cloxafu is generally well tolerated, but some people may experience side effects such as feeling sick, diarrhoea, stomach pain, and allergic reactions. Speak to your doctor if you experience any of these symptoms.

What should I do if I forget to take Cloxafu?

If you forget to take a dose, take it as soon as you remember. If it is close to the time for the next dose, skip the missed dose and take the next one when it is due. Do not take two doses at once.

Is Cloxafu available over the counter?

No, Cloxafu is a prescription-only medicine and is not available over the counter.

Is Cloxafu safe for children?

Cloxafu is generally safe for children, but it is important to speak to your doctor before giving any medication to a child.

Is Cloxafu available as a generic medicine?

Yes, Cloxafu is available in generic form and is usually cheaper than the branded version.

Is it safe to take Cloxafu long-term?

It is not advised to take Cloxafu for an extended period of time because it can cause antibiotic resistance in the body. If you have been prescribed Cloxafu for a long-term infection, make sure to take it as directed.

Can Cloxafu cause an allergic reaction?

Yes, an allergic reaction to Cloxafu is possible. Symptoms of an allergic reaction can include an itchy rash, swelling of the face, tongue, and throat, difficulty breathing, and dizziness. If you experience any of these symptoms, seek medical help immediately.

Can Cloxafu interact with other medicines?

Cloxafu can interact with certain medicines, such as antacids, or other antibiotics. It is important to tell your doctor about any other medicines you are taking before starting Cloxafu.

Can I take ibuprofen while taking Cloxafu?

It is not advised to take ibuprofen while taking Cloxafu as this can make it less effective. Speak to your doctor before taking any medicines while taking Cloxafu.

Can Cloxafu make my skin sensitive to the sun?

Yes, Cloxafu can make your skin more sensitive to sunlight. It is important to wear sunscreen when outside and avoid direct exposure to sunlight.

Does Cloxafu cause drowsiness?

No, Cloxafu does not cause drowsiness. However, some people may experience dizziness, so it is important to be careful when driving or operating machinery.

Can I take Cloxafu for a viral infection?

No, Cloxafu is an antibiotic and only works against bacterial infections. It will not work against a viral infection and should not be taken for one.

What should I do if I experience any side effects with Cloxafu?

If you experience any side effects while taking Cloxafu, speak to your doctor as soon as possible. The side effects should go away after you stop taking the medicine, but if they persist, you should seek medical advice.

Can Cloxafu be used to treat a sinus infection?

Cloxafu can be used to treat a sinus infection if it is caused by bacteria, but it will not be effective against a sinus infection caused by a virus.

Can I take Cloxafu if I have an intolerance to penicillin?

If you have an intolerance to penicillin, it is recommended that you do not take Cloxafu. Speak to your doctor about an alternative medication.

What is the usual dosage of Cloxafu?

The usual dose of Cloxafu is 250-500 mg, taken every 6 hours for adult doses and 250-500 mg, taken every 8 hours for children's doses. The exact dose will depend on your medical condition and the severity of the infection.

Should Cloxafu be taken with water?

Cloxafu can be taken with or without water, but it is important to take it as directed on the patient information leaflet.

Can Cloxafu be used to treat a urinary tract infection?

Yes, Cloxafu is commonly used to treat urinary tract infections caused by susceptible bacteria.

Can Cloxafu treat a tooth infection?

Yes, Cloxafu can be used to treat a tooth infection if it is caused by susceptible bacteria.

Is Cloxafu safe for elderly people?

Yes, Cloxafu is generally safe for elderly people, as long as it is taken as directed. However, it is important to speak to your doctor before taking Cloxafu if you are elderly, as they may need to adjust your dose.

Can Cloxafu cause diarrhea?

Yes, Cloxafu can cause diarrhea as a side effect. If you experience any other symptoms or the diarrhea persists, contact your doctor for advice.

Is Cloxafu safe for people with kidney disease?

Cloxafu is usually safe for people with kidney disease, but it is important to speak to your doctor before taking it. They may need to adjust your dose or monitor your kidney function.

Can I take Cloxafu for a sore throat?

Cloxafu is not usually prescribed for a sore throat, unless it is caused by a bacterial infection. If your sore throat is caused by a bacterial infection, speak to your doctor about the possibility of taking Cloxafu.

Can I take Cloxafu for a chest infection?

Yes, Cloxafu is commonly used to treat chest infections caused by susceptible bacteria.

Can Cloxafu treat an ear infection?

Yes, Cloxafu can be used to treat ear infections caused by susceptible bacteria.

What are the storage instructions for Cloxafu?

Cloxafu should be stored in a cool, dry, and dark place, away from direct sunlight. It should also be kept away from children and pets.

Can I take Cloxafu if I'm breast feeding?

It is generally safe to take Cloxafu while breast feeding, but you should speak to your doctor for advice. There may be an alternative medicine that you can take.

Can Cloxafu be taken with other antibiotics?

No, it is not recommended to take Cloxafu with other antibiotics, as this can reduce its effectiveness. Speak to your doctor before taking any other medicines while taking Cloxafu.

Does Cloxafu cause weight gain?

No, Cloxafu does not cause weight gain.

Can I take Cloxafu with paracetamol?

Yes, it is safe to take paracetamol while taking Cloxafu but do not take any other medicines, unless they have been approved by your doctor.

Is Cloxafu safe for people with diabetes?

Yes, Cloxafu is usually safe for people with diabetes, but it is important to speak to your doctor before taking any medication if you have diabetes.

Can I take Cloxafu on an empty stomach?

Yes, Cloxafu can be taken on an empty stomach. However, if you experience any stomach discomfort or an upset stomach while taking the medicine, then taking it with food may help.

Can Cloxafu be used to treat a skin infection?

Yes, Cloxafu can be used to treat skin infections caused by susceptible bacteria.