Closum Md

Closum Md Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Closum Md is a brand name. Its generic name is Clobazam.

Closum Md

Closum Md is an anticonvulsant and anxiolytic medicine in the benzodiazepine family of drugs used to treat anxiety disorders, epileptic seizures, and behavioral problems in children. It is also used to relieve muscle pain and discomfort due to various conditions.

Uses

Closum Md is used to treat a number of conditions including anxiety disorders, epilepsy, and behavioral problems in children. It is also used to treat certain types of seizures, as an adjunct to other anti-epileptic medications.

Mechanism Of Action

Closum Md works by suppressing the abnormal electrical activity in the brain that causes seizures and other neurological disorders. It does so by binding to the benzodiazepine receptor in the brain and activating the neurotransmitter GABA. This leads to increased levels of GABA, which in turn decreases the excitability of neurons. The binding of Closum Md also enhances the inhibitory effects of the neurotransmitter dopamine.

How Long Does It Take To Work?

Closum Md usually takes effect within about an hour of ingestion. The peak effect usually occurs 2-4 hours after consumption.

Absorption

Closum Md is rapidly and completely absorbed in the gastrointestinal tract and is widely distributed in the body. The mean bioavailability of Closum Md is 70%.

Route Of Elimination

Closum Md is metabolized in the liver and excreted through the kidneys. It is primarily eliminated as its glucuronide conjugate, which is excreted in the urine.

Dosage

The dosage of clobazam depends on the indication and patient’s age and medical condition. The dose may be increased as tolerated, typically starting with 0.5-1 mg daily in adults and 0.25 mg per day in children. The maximum dose for adults is 20 mg per day while the maximum dose in children is 10 mg per day.

Administration

Closum Md can be administered orally, rectally or intramuscularly. The oral form of clobazam must be taken with or after food. It should be taken with a full glass of water.

Side Effect

Some of the common side effects of clobazam include drowsiness, dizziness, headache, nausea, difficulty focusing, vision changes, and changes in weight or appetite. More serious side effects include confusion, seizures, difficulty breathing, unusual behavior, and severe allergic reactions.

Toxicity

Overdosing on clobazam can be serious and even life-threatening. Symptoms of overdose include excessive drowsiness, disorientation, confusion, depression, changes in muscle tone, respiratory depression, and coma.

Precautions

Before taking clobazam, it is important to inform your healthcare provider about any other medications that you are taking, any allergies you may have, and any medical conditions such as liver or kidney disease. Closum Md may impair your thinking or reactions and make you drowsy. Do not drive or do anything that requires alertness until you know how this medication affects you. Closum Md should not be used in children younger than 6 years old.

Interactions

Closum Md can interact with other medications. Some medications that may interact with clobazam include MAO inhibitors, benzodiazepines, alcohol, opioids, barbiturates, narcotics, muscle relaxants, and anti-seizure medications. Make sure to inform your healthcare provider about any medications that you are taking.

Disease Interaction

Closum Md can interact with certain conditions or diseases, including liver or kidney disease, glaucoma, depression, psychosis, and suicidal thoughts or behavior. Your healthcare provider may need to adjust or reduce your dosage of clobazam if you have any of these conditions.

Drug Interaction

Drug interactions can occur if clobazam is taken with other medications, such as MAO inhibitors, alcohol, muscle relaxants, narcotics, barbiturates, or other anticonvulsant drugs. Make sure to tell your healthcare provider about any other medications that you are taking.

Food Interactions

Food can interact with clobazam, particularly grapefruit juice and other citrus fruits. These can decrease the effectiveness of clobazam. It is best to avoid these foods while taking clobazam.

Pregnancy Use

Closum Md is not recommended for use during pregnancy due to potential risks to the unborn baby. Talk to your healthcare provider about other medications that can be taken during pregnancy.

Lactation Use

Closum Md is not recommended for use in breastfeeding women due to the potential for harm to the infant. Talk to your healthcare provider about other medications that can be taken while breastfeeding.

Acute Overdose

In case of acute overdose, seek immediate medical attention. Symptoms of overdose include excessive drowsiness, disorientation, confusion, depression, changes in muscle tone, respiratory depression, and coma.

Contraindications

Closum Md should not be used in people with known hypersensitivity to benzodiazepines, as well as in those who are pregnant, breastfeeding, or have a history of drug or alcohol abuse. It should also be used with caution in those with hepatic or renal impairment.

Use Direction

Closum Md should be taken as directed by your healthcare provider. For oral administration, the tablet should be taken with food. It should not be taken more than the prescribed amount. The dose may need to be adjusted depending on your response to the medication.

Storage Condition

Closum Md should be stored at room temperature in a tightly closed container. Keep this medicine away from light, moisture, and heat. Do not store in the bathroom or near a sink. Keep away from children and pets.

Volume Of Distribution

Closum Md has a mean volume of distribution of 0.8 L/kg.

Half Life

The half-life of clobazam is 27-47 hours.

Clearance

The mean clearance of clobazam is 17 L/hr.

Here you find in details version of Closum Md

Some Frequently Asked Questions About Closum Md

What is Closum Md?

Closum Md is a benzodiazepine medication used to treat anxiety and seizures. It can also be prescribed to help control agitation related to schizophrenia or to treat insomnia.

Why is Closum Md prescribed?

Closum Md is used to reduce the intensity of seizures caused by certain forms of epilepsy, as well as to help manage anxiety and agitation related to schizophrenia.

How does Closum Md work?

Closum Md works by binding to receptors in the brain to reduce the number of nerve impulses reaching the brain, which can reduce the frequency and intensity of seizures or reduce anxiety and agitation.

What are the possible side effects of Closum Md?

Common side effects of Closum Md include drowsiness, fatigue, dizziness, blurred vision, dry mouth, and nausea. Less common side effects may include breathing issues, confusion, muscle weakness, headache, depression, and changes in behavior.

Is Closum Md habit-forming?

Yes, Closum Md can be habit-forming and should be taken exactly as prescribed by a doctor. It’s important to follow all instructions and your doctor’s recommendations carefully.

What is the recommended dosage of Closum Md?

The recommended starting dose of Closum Md is 10 mg per day (or 2.5 mg twice per day for children). Your doctor may adjust your dose depending on your condition and response to treatment.

How long does it take Closum Md to work?

Closum Md usually takes effect within 1 to 2 hours after taking it. The effects of Closum Md can last for up to 8 hours.

What should I avoid while taking Closum Md?

People taking Closum Md should avoid operating machinery, driving, and other activities that require alertness, coordination, or physical dexterity. Alcohol should also be avoided while taking Closum Md as it may increase the risk of side effects.

Does Closum Md interact with any other drugs?

Yes, Closum Md can interact with other medications, including some antidepressants, antibiotics, narcotics, anticonvulsants, anti-anxiety drugs, and antihistamines. Talk to your doctor about any potential drug interactions before taking Closum Md.

What is an overdose of Closum Md?

An overdose of Closum Md can cause symptoms such as confusion, sedation, coma, loss of muscular coordination, or breathing problems. If you think you or someone else may have overdosed on Closum Md, call 911 immediately.

What should I do if I miss a dose of Closum Md?

If you miss a dose of Closum Md, take it as soon as you remember, unless it’s close to the time for your next dose. In that case, just skip the missed dose and take your next dose as scheduled. Do not double your dose to make up for a missed dose.

What should I do if I think I am having an allergic reaction to Closum Md?

If you think you are having an allergic reaction to Closum Md, contact your doctor right away. Symptoms of an allergic reaction include hives, difficulty breathing, swelling of the face, lips, tongue, or throat.

Can I take Closum Md if I am pregnant or breastfeeding?

Closum Md should not be used by pregnant or breastfeeding women unless the benefits outweigh the risks. Tell your doctor if you are pregnant, planning to become pregnant, or breastfeeding so they can adjust your dose if necessary.

Can I take Closum Md with other medications?

Closum Md can interact with other medications, so tell your doctor about any drugs, vitamins, or supplements you are taking. Your doctor can then adjust your dose if necessary to avoid interactions.

Can children take Closum Md?

Yes, Closum Md is approved for use in children ages 2 and older. However, the dosage and side effects may be different for children than for adults.

Can I drink alcohol while taking Closum Md?

No, it is not advised to drink alcohol while taking Closum Md as it may increase the risk of side effects. Talk to your doctor if you have any questions about drinking alcohol while taking Closum Md.

Does Closum Md cause weight gain?

Some people may experience weight gain while taking Closum Md, although weight gain is not listed as a common side effect. If you are concerned about weight gain, talk to your doctor.

Does Closum Md cause drowsiness?

Yes, drowsiness is a common side effect of Closum Md and can last up to 8 hours. Do not operate heavy machinery or drive while taking Closum Md if you experience drowsiness.

How long should I take Closum Md?

Closum Md should be taken as long as your doctor prescribes it. It is important to follow your doctor's instructions for taking Closum Md and not to stop taking it without consulting your doctor first.

What are the long-term effects of taking Closum Md?

The long-term effects of taking Closum Md have not been fully established. It is important to take Closum Md exactly as prescribed by your doctor and to not exceed the recommended dosage.

Can Closum Md be used to treat anxiety?

Yes, Closum Md can be used to treat anxiety. It is a benzodiazepine medication that works by binding to receptors in the brain to reduce the number of nerve impulses reaching the brain, which can reduce anxiety.

When should I take Closum Md?

Your doctor will advise you when to take Closum Md. It is typically taken one or two times per day, depending on your doctor’s instructions. It is important to take Closum Md at the same time each day to maintain a consistent level of the medication in your system.

What should I do if I experience serious side effects from taking Closum Md?

If you experience serious side effects from taking Closum Md, such as difficulty breathing or changes in behavior, contact your doctor or go to the emergency room right away.

Should I take Closum Md with food?

Closum Md can be taken with or without food. Your doctor will advise you on the best way to take it, but typically it is best to take it with food to reduce the risk of side effects.

How can I reduce my risk of experiencing side effects from Closum Md?

To reduce your risk of experiencing side effects from Closum Md, take it exactly as prescribed by your doctor. Avoid drinking alcohol and do not operate machinery while taking Closum Md. Talk to your doctor if you have any questions about taking Closum Md.

Are there any alternatives to Closum Md?

Yes, there are several alternatives to Closum Md, including other benzodiazepines and some anticonvulsants. Talk to your doctor about the best treatment for your condition.

Are there any drug interactions I should be aware of with Closum Md?

Yes, Closum Md can interact with other medications, including some antidepressants, antibiotics, narcotics, anticonvulsants, anti-anxiety drugs, and antihistamines. Talk to your doctor about potential drug interactions before taking Closum Md.

Are there any foods or drinks I should avoid while taking Closum Md?

It is important to avoid drinking alcohol while taking Closum Md as it may increase the risk of side effects. Talk to your doctor to find out if there are any other foods or drinks that you should avoid while taking Closum Md.

How should I store Closum Md?

Closum Md should be stored at room temperature, away from direct sunlight and moisture. Keep Closum Md out of reach of children and pets, and dispose of any unused medication properly.

Should I take other drugs while taking Closum Md?

Talk to your doctor before taking any other medications while taking Closum Md as some drugs can interact with each other and increase the risk of side effects. It is best to tell your doctor about any other drugs, vitamins, or supplements you are taking.

Can I take Closum Md if I have a history of depression?

Yes, Closum Md can be taken if you have a history of depression. However, it is important to tell your doctor about any mental health issues you may have as Closum Md can cause changes in mood or behavior.

Can I take herbal supplements while taking Closum Md?

It is best to check with your doctor before taking any herbal supplements while taking Closum Md, as some herbs can interact with Closum Md and increase the risk of side effects. Your doctor can advise you on the best course of action.

Does Closum Md work for everyone?

No, Closum Md may not work for everyone. Some people may experience no benefit from taking Closum Md, while others may experience both positive and negative effects. Talk to your doctor to discuss any concerns you may have about taking Closum Md.

Can Closum Md be used to treat insomnia?

Yes, Closum Md can be used to treat insomnia. It is a benzodiazepine medication that works by binding to receptors in the brain to reduce the number of nerve impulses reaching the brain, which can reduce anxiety and reduce the frequency of awakenings.

What are the signs of a Closum Md overdose?

Signs of a Closum Md overdose can include confusion, sedation, coma, loss of muscular coordination, or breathing problems. If you think you or someone else may have overdosed on Closum Md, call 911 immediately.

What are the withdrawal symptoms of Closum Md?

Withdrawal symptoms that can occur after stopping Closum Md may include headache, insomnia, nausea, vomiting, irritability, anxiety, dizziness, tremors, sweating, or seizures. It is important to talk to your doctor before stopping Closum Md to avoid serious withdrawal symptoms.

What should I do if my symptoms are not improving while taking Closum Md?

If your symptoms are not improving while taking Closum Md, contact your doctor right away. Your doctor may need to adjust your dose or change the medication you are taking.

Can I take Closum Md if I have a kidney or liver disease?

Yes, Closum Md can be taken if you have a kidney or liver disease. However, it is important to talk to your doctor as your dose may need to be adjusted. Your doctor can also advise you on any other precautions you may need to take while taking Closum Md.

Is Closum Md safe for long-term use?

The long-term safety of Closum Md has not been fully established. It is important to take Closum Md exactly as prescribed by your doctor, and not to exceed the recommended dosage. Talk to your doctor if you have any concerns about the long-term safety of Closum Md.