Clonac

Clonac Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Clonac is a brand name. Its generic name is Aceclofenac.

Introduction

Clonac is a non-steroidal anti-inflammatory drug (NSAID) used to manage pain, swelling, and inflammation due to various medical conditions. It is the racemic mixture of the two forms of a compound. It was developed in 1968 and approved for medical use in 1993.

Uses

Clonac is used to treat symptoms of osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis. It is also used in the treatment of musculoskeletal disorders, such as neck and back pain, sports injuries, sprains and strains, tendinitis, and bursitis.

Mechanism of Action

Clonac works by blocking the production of prostaglandins, hormones that cause inflammation and pain. By blocking this action, it reduces the pain and inflammation caused by these conditions.

How Long Does It Take to Work?

Clonac typically takes up to 2 weeks for its effect to be fully manifested. However, most patients experience relief within a few days.

Absorption

Clonac is rapidly absorbed from the gastrointestinal tract. It is metabolized in the liver and excreted in the urine and feces.

Route of Elimination

Clonac is secreted in the urine and feces. It is also partially metabolized by the liver.

Dosage

Clonac is available in 50 mg, 100 mg, and 200 mg doses. The recommended dose is one to two tablets taken orally every 8-12 hours as needed for pain relief. The maximum daily dose is 800 mg per day. The dose may be increased or decreased based on individual response and tolerance.

Administration

Clonac tablets should be taken orally, with or without food, as directed by your doctor. The tablets should be swallowed whole and should not be chewed or crushed.

Side Effects

Common side effects of Clonac include gastrointestinal discomfort, nausea, headache, dizziness, and rash. Serious side effects include difficulty breathing, chest pain, and liver or kidney problems. Contact your doctor if you experience severe or persistent side effects.

Toxicity

Clonac is generally well-tolerated, however, overdoses can result in serious toxicity. Symptoms of overdose include blurred vision, difficulty breathing, confusion, seizures, and coma. Seek immediate medical attention if you or someone you know has overdosed on this medication.

Precaution

Clonac should be taken with caution if you have a history of kidney, liver, or gastrointestinal disorder, asthma, dehydration, or blood clotting disorder. You should also avoid taking alcohol or other medications that can irritate the stomach while taking aceclofenac.

Interactions

Clonac may interact with certain other medications. Be sure to inform your doctor of any medications, supplements, or vitamins you are currently taking. This medication may also interact with other medical conditions or lifestyle choices.

Drug Interactions

Clonac can interact with certain other medications, including anti-inflammatory drugs, antidepressants, blood thinners, antibiotics, antifungal medications, and vitamin supplements. Be sure to tell your doctor and pharmacist about all medications you are currently taking, including any over-the-counter medications.

Food Interactions

Clonac may interact with certain foods. It is important to talk to your doctor about any dietary restrictions or food interactions that may occur when taking this medication.

Pregnancy Use

Clonac should not be used during pregnancy as it may cause harm to the fetus. Women who are pregnant or planning to become pregnant should not take this medication.

Lactation Use

Clonac should not be used during lactation as it may be secreted into breast milk. Women who are breastfeeding should not take this medication.

Acute Overdose

Overdose of aceclofenac can be potentially life-threatening. Symptoms of overdose include, blurred vision, difficulty breathing, confusion, seizures, and coma. Seek immediate medical attention if you or someone you know has overdosed on this medication.

Contraindication

Clonac should not be used in people with a history of stomach or intestinal ulcer, liver and kidney disease, and patients with a history of hypersensitivity to other drugs including Clonac.

Use Direction

Clonac should be taken exactly as prescribed by your doctor. Do not take more or less of the medication than directed. Do not take the medication more or less frequently than directed.

Storage Condition

Clonac should be stored at room temperature, away from light, moisture, and heat. Keep away from children and pets.

Volume of Distribution

Clonac has a large volume of distribution and is widely distributed throughout the body.

Half Life

The elimination half-life of aceclofenac is approximately 6 hours.

Clearance

Clonac is cleared from the body primarily by the kidneys. The oral clearance of the drug is approximately 40 mL/min.

Here you find in details version of Clonac

Some Frequently Asked Questions About Clonac

What is Clonac?

Clonac is a non-steroidal anti-inflammatory drug (NSAID) used for treating pain and inflammation in conditions such as rheumatoid arthritis, ankylosing spondylitis, and osteoarthritis.

What is the mechanism of action of Clonac?

Clonac is thought to work by inhibiting the activity of the enzyme cyclooxygenase (COX). Inhibition of COX leads to decreased synthesis of pro-inflammatory and painmediating prostaglandins, resulting in a reduction in inflammation and pain.

What is the dosage of Clonac?

The recommended adult dose of Clonac is 100 to 200 mg twice daily or as directed by the physician.

What are the side effects of Clonac?

The common side effects of Clonac include stomach upset, heartburn, nausea, vomiting, diarrhea, drowsiness, headache, constipation, joint pain, rash and itching.

What should be avoided while taking Clonac?

Alcohol should be avoided while taking Clonac as it can increase the risk of stomach ulcers and bleeding. ACE inhibitors, anticoagulants, diuretics, NSAIDs, and corticosteroids should also be avoided while taking Clonac.

Can Clonac be used for migraine?

Clonac is not usually recommended for the treatment of migraine headaches, although some patients may find it to be effective. Patients should discuss this with their doctor to determine if Clonac is an appropriate treatment.

Can I take Clonac with paracetamol?

Yes, it is safe to take Clonac with paracetamol. However, it is important to follow the dosages as prescribed by your doctor, and not to exceed the recommended dosages.

Can I take Clonac during pregnancy?

Clonac is not recommended during the first and third trimester of pregnancy. There is limited data on its use and safety during the second trimester of pregnancy, and it should be used only if the potential benefits outweigh the risks.

Is Clonac a muscle relaxant?

No, Clonac is not a muscle relaxant. It is a non-steroidal anti-inflammatory drug (NSAID) used to reduce pain and inflammation in conditions such as rheumatoid arthritis, ankylosing spondylitis, and osteoarthritis.

Can Clonac be used for headaches?

Clonac is not usually recommended for the treatment of headache. Patients should discuss this with their doctor to determine if Clonac is an appropriate treatment.

What are the serious side effects of Clonac?

Serious side effects of Clonac include signs of allergic reactions (hives, difficulty breathing, swelling of the face, lips, tongue, or throat), chest pain, increased blood pressure, shortness of breath, and bloody or black, tarry stools.

What is the difference between Clonac and Ibuprofen?

Clonac and ibuprofen are both non-steroidal anti-inflammatory drugs (NSAIDs) used for reducing pain and inflammation. The main difference between them is that Clonac is thought to have fewer gastrointestinal side effects than ibuprofen.

Can I take Clonac if I have high blood pressure?

Yes, you can take Clonac if you have high blood pressure. However, it is important to follow the dosages as prescribed by your doctor, and not to exceed the recommended dosages.

Is Clonac safe?

Clonac is generally safe and well-tolerated when taken at prescribed doses. However, it can cause side effects such as stomach upset, heartburn, nausea, vomiting, diarrhea, drowsiness, headache, constipation, joint pain, rash and itching.

Can Clonac be used to treat fever?

No, Clonac is not usually recommended for the treatment of fever. It is used to reduce pain and inflammation associated with conditions such as rheumatoid arthritis, ankylosing spondylitis, and osteoarthritis.

How long does Clonac take to work?

Clonac usually starts to work within a few hours of taking it. Maximum effects are usually seen within 1-2 weeks.

Can I take Clonac with warfarin?

No, it is not recommended to take Clonac with warfarin as it could increase the risk of bleeding. If you are taking warfarin then you should discuss this with your doctor before taking Clonac.

What is the maximum daily dose of Clonac?

The maximum daily dose of Clonac is 400 mg per day. Higher doses are not recommended and patients should not exceed the recommended dose.

Is Clonac available over the counter?

No, Clonac is a prescription medication available only through a doctor's prescription.

Is Clonac a strong painkiller?

Clonac is a medium strength painkiller used for treating pain and inflammation in conditions such as rheumatoid arthritis, ankylosing spondylitis, and osteoarthritis.

Can Clonac be used to treat gout?

Yes, Clonac can be used to treat gout. However, it is important to follow the dosage as prescribed by the doctor and not to exceed the recommended dosage.

Can Clonac be taken with food?

Yes, it is generally recommended to take Clonac with food or after meals to reduce the risk of stomach upset. It is important to follow your doctor's instructions when taking this medication.

Can I take Clonac before surgery?

No, it is not recommended to take Clonac before surgery as it may increase the risk of bleeding. You should discuss this with your doctor before taking this medication.

What should be done in case of an overdose?

If an overdose of Clonac is suspected then medical attention should be sought immediately. Symptoms of an overdose may include nausea, vomiting, dizziness, abdominal pain, and drowsiness.

What precautions should I take while using Clonac?

It is important to follow all the instructions and precautions provided by the doctor while taking Clonac. It is also important to keep your doctor updated about any medical conditions you have and be aware of any medications, supplements, or herbal remedies you are taking that could interact with Clonac.

What drug interactions can occur when taking Clonac?

Clonac may interact with certain drugs, such as ACE inhibitors, anticoagulants, diuretics, NSAIDs, and corticosteroids. It is important to discuss with your doctor any medications, supplements, or herbal remedies you are taking, to prevent any potential drug interactions.

Is Clonac safe for long-term use?

Clonac is generally safe when taken for a short period of time. Long-term use of Clonac can increase the risk of side effects, such as gastrointestinal bleeding, increased risk of heart attack, stroke, and kidney damage. If you are taking Clonac for a long-term period, it is important to discuss this with your doctor.

Can Clonac cause anemia?

Yes, long-term use of Clonac can cause anemia due to decreased production of red blood cells. If you are taking Clonac for long-term use, it is important to discuss with your doctor about the potential risks of anemia.

Can Clonac cause liver damage?

Yes, Clonac can cause liver damage in rare cases. If you experience any signs of liver damage such as yellowing of the eyes or skin, dark urine, or abdominal pain, you should seek medical attention immediately.

Can Clonac cause kidney damage?

Yes, long-term use of Clonac can cause kidney damage in rare cases. If you experience any signs of kidney damage such as decreased urination, nausea, vomiting, or fluid retention, you should seek medical attention immediately.

Can Clonac cause weight gain?

No, Clonac does not usually cause weight gain. However, it is possible for certain side effects, such as abdominal pain, nausea, and vomiting, to lead to decreased appetite and weight loss.

Can I take Clonac with aspirin?

No, it is not recommended to take Clonac with aspirin as it may increase the risk of stomach ulcers and bleeding. If you are taking aspirin then you should discuss this with your doctor before taking Clonac.

Can I take Clonac for menstrual cramps?

Yes, Clonac can be used to treat mild to moderate menstrual cramps. However, it is important to follow the dosage as prescribed by the doctor and not to exceed the recommended dosage.

Does Clonac cause drowsiness?

Yes, Clonac may cause drowsiness. If you experience drowsiness after taking this medication then it is important to avoid activities that require alertness such as driving or operating machinery.

Does Clonac interact with warfarin?

Yes, Clonac can interact with warfarin and increase the risk of bleeding. If you are taking warfarin then you should discuss this with your doctor before taking Clonac.

What is the onset of action of Clonac?

The onset of action of Clonac is usually within a few hours of taking it. Maximum effects are usually seen within 1-2 weeks.

How long does Clonac take to work?

The effects of Clonac may take a few hours to be felt. Maximum effects are usually seen within 1-2 weeks.

Is Clonac safe for children?

Clonac is not recommended for use in children under 12 years of age. If a child needs to take this medication then it should be taken only under the supervision of a doctor.

Can Clonac be taken with food?

Yes, it is generally recommended to take Clonac with food or after meals to reduce the risk of stomach upset. It is important to follow your doctor's instructions when taking this medication.

What is the half-life of Clonac?

The half-life of Clonac is approximately 8 to 12 hours.

Is Clonac addictive?

No, Clonac is not addictive.

Can I take Clonac if I have asthma?

Yes, you can take Clonac if you have asthma. However, it is important to discuss this with your doctor to ensure that Clonac is