Clocef

Clocef Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Clocef is a brand name. Its generic name is Cefaclor.

Introduction

Clocef, also known as Clocefum or Clocef Extended-Release, is a cephalosporin antibiotic used to treat bacterial infections. It is typically used to treat ear infections, urinary tract infections, sinus infections, and bronchitis. Clocef may also be prescribed for other conditions, as determined by a doctor.

Uses

Clocef is used for the treatment of mild to moderate bacterial infections caused by susceptible bacteria in the following locations:
  • Respiratory tract, including bronchitis and pneumonia
  • Gastrointestinal tract, including infections of the esophagus, stomach and small intestine, gall bladder and bile ducts
  • Urinary tract, including infections of the bladder and kidney
  • Skin and soft tissue, including wound infections and abscesses

Mechanism of Action

Clocef works by inhibiting the synthesis of bacterial cell walls, thus slowing down the growth and multiplication of the bacteria that cause infections. This ultimately leads to the death of the bacteria, clearing the infection and allowing the patient to recover.

How Long Does It Take to Work?

Clocef usually starts to work within a few hours of being taken. However, it may take several days for a full course of treatment to clear the infection fully.

Absorption

Clocef is an oral medication, and is quickly and completely absorbed through the gastrointestinal tract. Peak concentrations in the bloodstream can be seen in 1 to 4 hours after administration.

Route of Elimination

Clocef is eliminated primarily through the kidneys in the form of metabolites, and is excreted in the urine.

Dosage

Clocef is available in several different dosages, and the correct dose will depend on various factors such as the patient's age, weight, and the severity of the infection. The typical dosage for adults and adolescents (12 years and older) is 250 to 500 mg taken two to three times a day. For children under 12, the dosage will depend on the child's weight and will be determined by a doctor.

Administration

Clocef should be taken with a full glass of water and can be taken with or without food. The tablets and capsules should be swallowed whole and should not be crushed or chewed.

Side Effect

As with any medication, there is a chance of side effects when taking Clocef. Common side effects may include nausea, vomiting, flatulence, and diarrhoea. Other less common side effects may include anaphylactic reactions, hepatitis, neuropathy, skin rash, and haemolytic anaemia.

Toxicity

Clocef is generally well tolerated and the risk of toxicity is low. However, if too much of the medication is taken, it can be toxic and cause serious side effects. If a patient suspects they have taken an overdose, they should seek immediate medical attention.

Precautions

Clocef should not be used in patients with known hypersensitivity to cephalosporins or drugs in the same class, or any of the ingredients in the medication. It should also be used cautiously in patients with renal or hepatic impairment, or in pregnant or breastfeeding women.

Interactions

Clocef has the potential to interact with other medications, including non-steroidal anti-inflammatory drugs (NSAIDs), oral anticoagulants, antifungals, and oral contraceptives. Patients should inform their doctor about any medications or supplements they are taking.

Disease Interaction

Patients with pre-existing conditions, such as asthma, kidney or liver disease, or blood disorders, should inform their doctor before taking Clocef. The medication can cause an allergic reaction in some patients.

Drug Interactions

Clocef can interact with other medications, and it is important to inform your doctor about any medications or supplements you are taking so that may be taken into account.

Food Interactions

Clocef should be taken at least two hours before or after a meal. Taking it with food may increase the absorption and reduce the effectiveness of the medication.

Pregnancy Use

Clocef is classified as a Pregnancy Category B drug, which means that it is not known to be harmful to an unborn baby. However, it should only be used if the benefit outweighs the risk.

Lactation Use

It is not known whether Clocef is excreted in breast milk, and therefore it is not recommended for use during lactation.

Acute Overdose

If an overdose of Clocef is suspected, the patient should seek immediate medical attention. Symptoms of an overdose may include nausea, vomiting, and diarrhoea.

Contraindication

Clocef should not be used by patients who are allergic to it or other cephalosporin antibiotics. It should also not be used in patients with renal or hepatic impairment.

Use Directions

Clocef tablets should be taken as directed by a doctor. It should be taken with a full glass of water and can be taken with or without food. The tablets and capsules should be swallowed whole and should not be crushed or chewed.

Storage Conditions

Clocef tablets should be stored at room temperature in a tightly sealed container. It should be kept in a dry place away from direct sunlight and out of reach of children.

Volume of Distribution

Clocef is well distributed to some body tissues and fluids, such as pleural and synovial fluids, as well as the gallbladder.

Half-Life

Clocef has a half-life of approximately two hours.

Clearance

Clocef is eliminated primarily through the kidneys in the form of metabolites, and is excreted in the urine.

Here you find in details version of Clocef

Some Frequently Asked Questions About Clocef

What is Clocef?

Clocef is an oral cephalosporin antibiotic used to treat a variety of bacterial infections in the body.

What is Clocef used for?

Clocef is commonly used to treat infections caused by bacteria, such as: bronchitis, otitis media, sinus infections, pneumonia, urinary tract infections, and skin infections.

Is Clocef a broad-spectrum antibiotic?

Yes, Clocef is a broad-spectrum antibiotic, meaning it is effective against a wide range of bacterial infections.

What types of bacteria does Clocef treat?

Clocef is effective against Gram-positive and Gram-negative bacteria, as well as certain anaerobic bacteria.

How quickly does Clocef work?

The effects of Clocef can be seen within the first few days of starting treatment. However, it is important to complete the entire course of treatment to ensure that the infection is totally eradicated.

Do I need a prescription to get Clocef?

Yes, Clocef is a prescription medication and must be obtained from a healthcare professional.

How do I take Clocef?

Clocef should be taken orally with a full glass of water. It is usually taken every 8 or 12 hours, or as directed by your doctor. It is important to take all of the doses in the prescribed course of treatment to ensure that the infection is totally eradicated.

What are the side effects of Clocef?

Common side effects of Clocef include nausea, vomiting, diarrhea, rash, and itching. If these symptoms persist or worsen, it is important to contact your doctor. You should also contact your doctor immediately if you experience any serious side effects, such as difficulty breathing, severe abdominal pain, or dark urine.

What should I avoid while taking Clocef?

It is important to avoid alcohol, grapefruit juice, and other products that may interact with Clocef while taking this medication. Also, you should avoid taking antacids within 2 hours of taking Clocef, as this may reduce its effectiveness.

Does Clocef interact with other medications?

Yes, Clocef can interact with other medications, such as antacids, anticonvulsants, certain diuretics, lithium, methotrexate, phenytoin, probenecid, and certain antibiotics. It is important to tell your doctor about all medications that you are currently taking in order to avoid drug interactions.

What if I forget to take a dose of Clocef?

If you forget to take a dose of Clocef, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take your next dose as scheduled. Do not take a double dose to make up for the missed dose.

Can Clocef cause an allergic reaction?

Yes, Clocef can cause an allergic reaction, which may include symptoms such as: difficulty breathing, hives, swollen face, and rash. Seek medical attention immediately if you experience any of these symptoms.

Can I take Clocef if I am pregnant or breastfeeding?

It is generally not recommended to take Clocef if you are pregnant or breastfeeding. Speak with your doctor to discuss the risks and benefits of taking Clocef while pregnant or breastfeeding.

Can I give Clocef to my child?

Clocef is generally not recommended for children under the age of 12. Speak with your doctor to determine if Clocef is safe for your child.

What should I do if I experience an overdose of Clocef?

It is important to seek medical attention immediately if you experience an overdose of Clocef. Symptoms of an overdose may include nausea, vomiting, and abdominal pain.

Does Clocef cause drowsiness?

Yes, Clocef can cause drowsiness or dizziness. Avoid operating machinery or driving while taking this medication.

Can I take Clocef with food?

Yes, it is safe to take Clocef with food. However, it is important to remember not to take antacids within 2 hours of taking Clocef.

How should I store Clocef?

Clocef should be stored at room temperature in a dry, dark place. Keep the medication away from direct light, heat, and moisture.

Is Clocef safe for long-term use?

It is generally not recommended to use Clocef for long-term use. Speak with your doctor about the risks and benefits of using Clocef for long-term treatment.

Does Clocef affect birth control?

Yes, Clocef can interact with certain birth control medications. Speak with your doctor to determine the best method of birth control to use while taking Clocef.

Can I take Clocef with dairy products?

It is generally safe to take Clocef with dairy products. However, it is important to remember not to take antacids within 2 hours of taking Clocef.

Can I take Clocef for a viral infection?

No, Clocef is only effective against bacterial infections, and will not be effective for treating a viral infection.

Can I take Clocef with ibuprofen?

Yes, it is generally safe to take Clocef with ibuprofen. However, it is important to discuss any drug interactions with your doctor.

Does Clocef cause weight gain?

Weight gain is not a common side effect of Clocef. If you experience unexplained weight gain while taking Clocef, speak with your doctor.

Can Clocef cause kidney damage?

There is a risk of kidney damage with long-term use of Clocef, especially at high doses. It is important to discuss any potential risks with your doctor before taking Clocef.

Can I take Clocef with an ACE inhibitor?

Yes, it is generally safe to take Clocef with an ACE inhibitor. However, it is important to discuss any drug interactions with your doctor.

Is Clocef safe for elderly patients?

Yes, Clocef can be used by elderly patients. However, elderly patients may be more prone to side effects, such as nausea, vomiting, and abdominal pain. Speak with your doctor about the risks and benefits of taking Clocef for elderly patients.

What should I do if I experience an allergic reaction to Clocef?

If you experience an allergic reaction to Clocef, such as difficulty breathing, hives, or rash, seek medical attention immediately. You should also contact your doctor if any of these symptoms persist or worsen.

Can I take Clocef with vitamins?

It is generally safe to take Clocef with vitamins. However, it is important to discuss any potential drug interactions with your doctor before taking Clocef.

Is Clocef effective against MRSA?

Yes, Clocef is effective against Methicillin-resistant Staphylococcus aureus (MRSA).

Can I take Clocef with Tylenol?

Yes, it is generally safe to take Clocef with Tylenol. However, it is important to discuss any potential drug interactions with your doctor before taking Clocef.

Does Clocef treat strep throat?

Yes, Clocef is effective against Streptococcus pyogenes, which can cause strep throat.

Can I take Clocef while breastfeeding?

It is generally not recommended to take Clocef while breastfeeding. Speak with your doctor to discuss the risks and benefits of taking Clocef while breastfeeding.

Is Clocef effective against staph infections?

Yes, Clocef is effective against many types of staph infections, including Methicillin-resistant Staphylococcus aureus (MRSA).

Does Clocef cause nausea?

Yes, nausea is a common side effect of Clocef. If this symptom persists or worsens, it is important to contact your doctor.

Does Clocef treat UTIs?

Yes, Clocef is effective against urinary tract infections (UTIs).

Can I take Clocef if I am allergic to penicillin?

Yes, it is generally safe for those who are allergic to penicillin to take Clocef, as Clocef is not a penicillin-based antibiotic.

Can I take Clocef with other antibiotics?

It is generally not recommended to take Clocef with other antibiotics, as this may increase the risk of drug interactions. Speak with your doctor before taking Clocef with other medications.

Can I take Clocef if I have asthma?

Yes, Clocef can be taken by those with asthma. However, there may be a risk of an allergic reaction. Speak with your doctor to discuss the risks and benefits of taking Clocef if you have asthma.

Does Clocef treat ear infections?

Yes, Clocef is commonly used to treat otitis media (ear infections).

Can I take Clocef with probiotics?

Yes, it is generally safe to take Clocef with probiotics. However, it is important to discuss any potential drug interactions with your doctor before taking Clocef.

Does Clocef have any long-term effects?

Long-term use of Clocef can cause kidney damage, especially at high doses. Speak with your doctor to discuss the risks and benefits of taking Clocef for long-term treatment.