Clarithromycin

Clarithromycin Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Clarithromycin is a brand name. Its generic name is Clarithromycin.

Introduction

Clarthromycin is a type of antibiotic drug, used for treatment of many different bacterial infections. It belongs to the class of macrolide antibiotics, which work by interfering with bacterial protein synthesis.

Uses

Clarthromycin is used for treating a wide range of bacterial infections, such as ear infections, pneumonia, skin infections, urinary tract infections, tonsillitis, and some sexually transmitted disease. It is also used in some cases of Legionnaires' disease, sinusitis, and throat infections.

Mechanism of Action

Clarthromycin works by inhibiting bacterial protein synthesis. It does this by blocking the action of a bacterial enzyme called transpeptidase. This enzyme is responsible for constructing new proteins in the bacteria, which are required for the bacteria to survive and reproduce. By blocking the function of this enzyme, the drug is able to stop bacterial proliferation.

How Long Does it Take to Work?

Clarthromycin usually begins to take effect within 12-24 hours after it is taken. It may take up to 3 days to start feeling relief from the symptoms of the infection.

Absorption

Clarthromycin is typically well absorbed in the digestive tract, with an absorption rate of approximately 60%. It is also rapidly distributed in the tissues and bloodstream.

Route of Elimination

Clarthromycin is eliminated mainly unchanged in the urine. It is also eliminated in smaller amounts by the kidneys and gastrointestinal tract.

Dosage

Clarthromycin is available in generic and brand-name versions as 250 mg or 500 mg tablets. The usual recommended dosage is 250-500 mg twice daily. For severe infections, it is often recommended to be taken every 8 hours.

Administration

Clarthromycin should be taken with food or a glass of milk. It can also be taken with a full glass of water. It should be taken at the same time each day.

Side Effect

Common side effects of clarthromycin include nausea, diarrhea, vomiting, abdominal pain, dizziness, vertigo, headache, and rash. It may also cause liver damage in rare cases, which can lead to liver failure.

Toxicity

Clarthromycin is generally well tolerated. However, an overdose may lead to serious side effects such as seizures, coma, and liver failure. An overdose should be treated as soon as possible.

Precaution

Clarthromycin is not recommended for people who have had an allergic reaction to it before. It should also be used with caution in people with kidney or liver disease, and in people with a history of arrhythmia.

Interaction

Clarthromycin may interact with certain drugs, including antacids, vitamin/mineral supplements, warfarin, or drugs used to treat arrhythmias. It may also interact with other antibiotics, so it is important to check with your doctor before taking it.

Disease Interaction

Clarthromycin may interact with certain medical conditions, including arrhythmias, liver disease, or kidney disease. It may also interact with diseases such as HIV, tuberculosis, or any autoimmune diseases.

Drug Interaction

Clarthromycin may interact with certain drugs, such as antacids, vitamin/mineral supplements, warfarin, or drugs used to treat arrhythmias. It is important to check with your doctor before combining it with any other medications or supplements.

Food Interactions

Clarthromycin may interact with certain foods, such as dairy products, alcohol, or foods that are high in fat. It is important to check with your doctor before taking this medication with any foods.

Pregnancy Use

Clarthromycin is not recommended for pregnant women, as it may cause harm to the unborn baby. Women who are pregnant or breastfeeding should consult a doctor before taking this medication.

Lactation Use

Clarthromycin is not recommended for women who are breastfeeding, as it may pass into breast milk and cause harm to the baby. Women who are breastfeeding should consult a doctor before taking this medication.

Acute Overdose

An overdose of clarthromycin can lead to serious side effects, such as seizures, coma, and liver failure. If an overdose is suspected, it is important to seek medical attention as soon as possible.

Contraindication

Clarthromycin should not be taken by people who have had an allergic reaction to it before. It should also be avoided in people with liver disease and arrhythmias.

Use Direction

Clarthromycin should be taken as directed by your doctor. It is usually taken once or twice daily with food or a full glass of water.

Storage Condition

Clarthromycin should be stored in a cool, dry place away from light and humidity. It should be stored at room temperature.

Volume of Distribution

The volume of distribution of clarthromycin is approximately 0.4 L/kg.

Half Life

The half-life of clarthromycin is approximately 3-4 hours.

Clearance

The clearance of clarthromycin is approximately 1 ml/min/kg.

Here you find in details version of Clarithromycin

Some Frequently Asked Questions About Clarithromycin

What is Clarithromycin?

Clarithromycin is an antibiotic and is used to treat certain types of bacterial infections.

What is the generic name of Clarithromycin?

The generic name of Clarithromycin is Clarithromycin.

What are the common side effects of Clarithromycin?

Common side effects of Clarithromycin include nausea, vomiting, diarrhea, stomach upset, dizziness, headache, and skin rash.

Is Clarithromycin used to treat bronchitis?

Yes, Clarithromycin may sometimes be used to treat bronchitis, as it is an antibiotic and can help fight bacterial infections.

Does Clarithromycin treat urinary tract infections?

Yes, Clarithromycin may be an effective treatment for urinary tract infections caused by certain bacteria.

Can Clarithromycin be used to treat other illnesses?

Yes, Clarithromycin may be used to treat other conditions as determined by your doctor, such as strep throat, sinus infections, and skin infections.

What are the possible side effects of Clarithromycin?

Possible side effects of Clarithromycin include nausea, vomiting, diarrhea, stomach upset, headaches, dizziness, and skin rash.

Can Clarithromycin interact with other medications?

Yes, Clarithromycin can interact with other medications, including certain antibiotics, antidepressants, antifungals, and heart medications. It is important to discuss with your doctor any medications you are taking before taking Clarithromycin.

Can I drink alcohol while taking Clarithromycin?

No, it is not recommended to drink alcohol while taking Clarithromycin. Alcohol may increase the side effects of the medication and interfere with how the medication works.

How long does it take for Clarithromycin to work?

Clarithromycin begins to work within 24 hours of taking the medication. However, it may take several days for the full effect of the medication to be seen.

What should I do if I have an allergic reaction to Clarithromycin?

If you experience an allergic reaction to Clarithromycin, such as hives, difficulty breathing, or swelling of the face, lips, tongue, or throat, you should stop taking the medication and seek medical attention immediately.

Can Clarithromycin be taken with food?

Yes, Clarithromycin can be taken with food. It is also recommended to take Clarithromycin with a full glass of water and with a meal or snack.

What happens if I miss a dose of Clarithromycin?

If you miss a dose of Clarithromycin, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and take your next dose at the regular time.

Is there anything I should avoid while taking Clarithromycin?

You should avoid taking antacids containing aluminum or magnesium within 2 hours before or after taking Clarithromycin. You should also avoid eating grapefruit or drinking grapefruit juice while taking the medication.

Can children take Clarithromycin?

Yes, Clarithromycin can be used in children, but only after consulting with a doctor. The dosage and length of treatment will depend on the child's weight and the severity of the infection.

Is Clarithromycin safe for pregnant women?

Yes, Clarithromycin is generally considered safe for pregnant women, unless otherwise advised by a doctor. It is important to discuss the risks and benefits of taking Clarithromycin with a doctor before taking the medication.

Does Clarithromycin cause drowsiness?

Clarithromycin may cause drowsiness or dizziness. It is important not to drive or operate heavy machinery until you know how Clarithromycin affects you.

Can Clarithromycin cause liver damage?

Yes, Clarithromycin can cause liver damage. It is important to contact a doctor immediately if you experience any signs of liver damage, such as nausea, vomiting, unusual tiredness, abdominal pain, dark urine, or yellowing of the eyes or skin.

Is Clarithromycin used to treat skin infections?

Yes, Clarithromycin can be used to treat skin infections caused by certain bacteria.

Can Clarithromycin cause hearing loss?

Yes, Clarithromycin can cause hearing loss and tinnitus. It is important to contact a doctor immediately if you experience any hearing loss or ringing in the ears while taking Clarithromycin.

Is Clarithromycin the same as Amoxicillin?

No, Clarithromycin and Amoxicillin are two different antibiotics. While both are used to treat bacterial infections, they are used to treat different types of infections.

Can Clarithromycin treat a urinary tract infection?

Yes, Clarithromycin can be an effective treatment for urinary tract infections caused by certain bacteria.

Should I take Clarithromycin on an empty stomach?

No, it is recommended to take Clarithromycin with a meal or snack and with a full glass of water.

Can Clarithromycin cause changes in blood sugar levels?

Yes, Clarithromycin can cause changes in blood sugar levels. It is important to monitor your blood sugar levels while taking Clarithromycin.

Does Clarithromycin treat strep throat?

Yes, Clarithromycin may be used to treat strep throat, depending on the severity of the infection.

Does Clarithromycin cause constipation?

Yes, Clarithromycin can cause constipation. It is important to hydrate and stay active while taking the medication.

How long does it take for Clarithromycin to clear up an infection?

The length of time it takes for Clarithromycin to clear up an infection will depend on the type of infection. However, it usually takes several days for the infection to improve.

Can I take Clarithromycin if I am allergic to penicillin?

Yes, Clarithromycin can be taken if you are allergic to penicillin. However, it is important to let your doctor know if you are allergic to penicillin before taking Clarithromycin.

Does Clarithromycin cause headaches?

Yes, Clarithromycin may cause headaches. If the headaches become severe or persistent, it is important to contact your doctor.

What should I do if I experience diarrhea while taking Clarithromycin?

If you experience diarrhea while taking Clarithromycin, it is important to drink plenty of fluids and rest. If the diarrhea persists or becomes worse, it is important to contact your doctor.

Can Clarithromycin be used to treat sinus infections?

Yes, Clarithromycin may be used to treat sinus infections caused by certain bacteria.

Should I take Clarithromycin with food?

Yes, it is recommended to take Clarithromycin with food and with a full glass of water.

Can Clarithromycin be used by elderly patients?

Yes, Clarithromycin can be used by elderly patients. However, it is important to discuss the risks and benefits of taking Clarithromycin with your doctor before taking the medication.

Does Clarithromycin cause dry mouth?

Yes, Clarithromycin can cause dry mouth. It is important to drink plenty of fluids while taking Clarithromycin.

Can Clarithromycin be taken with other medications?

Yes, Clarithromycin can be taken with other medications, but it is important to discuss any other medications you are taking with your doctor before taking Clarithromycin.

Is Clarithromycin used to treat ear infections?

Yes, Clarithromycin may be used to treat ear infections caused by certain bacteria.

Does Clarithromycin cause nausea?

Yes, Clarithromycin can cause nausea. If the nausea becomes severe or persistent, it is important to contact your doctor.

Can Clarithromycin cause heartburn?

Yes, Clarithromycin can cause heartburn. It is important to take the medication with food and to avoid lying down for at least 30 minutes after taking the medication.

Does Clarithromycin interact with any supplements?

Yes, Clarithromycin can interact with certain supplements. It is important to discuss any supplements you are taking with your doctor before taking the medication.

Can Clarithromycin cause loss of appetite?

Yes, Clarithromycin can cause loss of appetite. If the loss of appetite becomes severe or persists, it is important to contact your doctor.

Can Clarithromycin be used to treat strep throat?

Yes, Clarithromycin may be used to treat strep throat, depending on the severity of the infection.

Should I continue taking Clarithromycin even if I feel better?

Yes, it is important to continue taking Clarithromycin for the full duration of the treatment prescribed by the doctor, even if you feel better.